Critical issues in alcohol and drugs of abuse testing

書誌事項

Critical issues in alcohol and drugs of abuse testing

edited by Amitava Dasgupta

Academic Press, an imprint of Elsevier, c2019

2nd ed

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more.

目次

1. Alcohol: Pharmacokinetics, Health Benefits with Moderate Consumption and Toxicity 2. Alcohol Analysis in Various Matrixes: Clinical versus Forensic Testing 3. Alcohol Biomarkers: Clinical Issues and Analytical Methods 4. Genetic Markers Related to Alcohol Use and Abuse 5. Ethylene Glycol and Other Glycols: Testing and Interpretation Issues 6. Introduction to Drugs of Abuse 7. Legal Aspects of Drug Testing in U.S. Military and Civil Courts 8. Pharmacogenomics of Drugs of Abuse 9. Immunoassay Design for Screening of Drugs of Abuse 10. Issues of Interferences with Immunoassays used for Screening of Drugs of Abuse in Urine 11. Point of Care Devices for Drugs of Abuse Testing: Limitations and Pitfalls 12. Drugs of Abuse Screening and Confirmation with Lower Cutoff values 13. Overview of Analytical Methods in Drugs of Abuse Analysis: Gas Chromatography/Mass Spectrometry, Liquid Chromatography Combined with Tandem Mass Spectrometry and Related Methods 14. High Resolution Mass Spectrometry: An Emerging Analytical method for drug testing 15. Confirmation Methods for SAMHSA Drugs and Other Commonly Abused Drugs 16. Critical Issues when Testing for Amphetamine Type Stimulants: Pitfalls of Immunoassay Screening and Mass Spectrometric Confirmation for Amphetamines, Methamphetamines, and Designer Amphetamines 17. Cocaine, Crack Cocaine and Ethanol: A Deadly Mix 18. Drug assisted sexual assaults: Toxicology, Fatality and Analytical Challenge 19. Overview of Common Designer Drugs 20. Novel Psychoactive Substances: An Overview 21. Review of Bath Salts on Illicit Drug Market 22. Review of Synthetic Cannabinoids on Illicit Drug Market 23. Application of Liquid chromatography combined with high resolution mass spectrometry for urine drug testing 24. Forensic Toxicology in Death Investigation 25. Drug Testing in Pain Management 26. How do people try to beat drugs test? Effects of synthetic urine, substituted urine, diluted urine and in vitro urinary adulterants on drugs of abuse testing 27. When Hospital Toxicology Report is Negative in a Suspected Overdosed Patient: Strategy of Comprehensive Drug Screen using Liquid Chromatography combined with Mass Spectrometry 28. Testing of Drugs in Oral Fluid, Sweat, Hair and Nail: analytical, Interpretative and Specimen Adulteration Issues 29. Advances in Meconium Analysis for Assessment of Neonatal Drug Exposure 30. Analytical True Positive Drug Tests Due to Use of Prescription and Non-Prescription Medications 31. Analytical True Positive: Poppy Seed Products and Opiate Analysis 32. Miscellaneous Issues: Paper Money contaminated with Cocaine and Other Drugs, Cocaine Containing Herbal Teas, Passive Exposure of Marijuana, Ingestion of Hemp Oil and Occupational Exposure to Controlled Substances 33. Abuse of Magic Mushroom, Peyote cactus, LSD, Khat, and Volatiles 34. Performance Enhancing Drugs in Sports

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