Chiral separations : methods and protocols

書誌事項

Chiral separations : methods and protocols

edited by Gerhard K.E. Scriba

(Methods in molecular biology / John M. Walker, series editor, 1985)(Springer protocols)

Humana Press, c2019

3rd ed

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This detailed book focuses on analytical separations by chromatographic and electrophoretic techniques, providing some overview along with numerous practically-oriented applications of the most important analytical techniques in chiral separation sciences. While some compounds may only be enantioseparated with one technique based on the physico-chemical properties, often the analyst can choose between two or more analytical techniques for a given analyte, which requires knowledge of the strengths and weaknesses of each technique in order to select the most appropriate method for the given problem. This collection binds that knowledge in one volume. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Chiral Separations: Methods and Protocols, Third Edition serves as a helpful guide for analytical chemists working on stereochemical problems in the fields of pharmacy, chemistry, biochemistry, food chemistry, molecular biology, forensics, environmental sciences, or cosmetics in academia, government, or industry.

目次

1. Recognition Mechanisms of Chiral Selectors: An Overview Gerhard K.E. Scriba 2. Enantioseparation by Thin Layer Chromatography Rituraj Dubey and Ravi Bhushan 3. Enantioseparations by Gas Chromatography Using Porous Organic Cages as Stationary Phase Sheng-Ming Xie, Jun-Hui Zhang, and Li-Ming Yuan 4. Chiral Metabolomics Using Triazine-Based Chiral Labeling Reagents by UPLC-ESI-MS/MS Toshimasa Toyo'oka 5. Chiral Mobile Phase Additives in HPLC Enantioseparations Lushan Yu, Shengjia Wang, and Su Zeng 6. Polysaccharide-Based Chiral Stationary Phases for Enantioseparations by High Performance Liquid Chromatography: An Overview Bezhan Chankvetadze 7. HPLC Enantioseparations with Polysaccharide-Based Chiral Stationary Phases in HILIC Conditions Roberto Cirilli 8. Functional Cyclodextrin-Clicked Chiral Stationary Phases for Versatile Enantioseparations by HPLC Jie Zhou, Jian Tang, and Weihua Tang 9. HPLC Enantioseparation on Cyclodextrin-Based Chiral Stationary Phases Xiaoxuan Li and Yong Wang 10. Hybrid Organic-Inorganic Materials Containing a Nanocellulose Derivative as Chiral Selector Liang Zhao, Hui Li, Shuqing Dong, and Yanping Shi 11. Cyclofructans as Chiral Selectors: An Overview Garrett Hellinghausen and Daniel W. Armstrong 12. High-Performance Liquid Chromatography Enantioseparations Using Macrocyclic Glycopeptide-Based Chiral Stationary Phases: An Overview Istvan Ilisz, Timea Orosz, and Antal Peter 13. Application of Sub-2 Micron Particles Silica Hydride Derivatized with Vancomycin for Chiral Separations by Nano-Liquid Chromatography Chiara Fanali and Salvatore Fanali 14. Cinchona Alkaloid-Based Zwitterionic Chiral Stationary Phases Applied for Liquid Chromatographic Enantiomer Separations: An Overview Istvan Ilisz, Attila Bajtai, Antal Peter, and Wolfgang Lindner 15. Enantioseparations by High Performance Liquid Chromatography Based on Chiral Ligand-Exchange Federica Ianni, Lucia Pucciarini, Andrea Carotti, Roccaldo Sardella, and Benedetto Natalini 16. Applications of Chiral Supercritical Fluid Chromatography Emmanuelle Lipka 17. Chiral Separations by Countercurrent Chromatography Sheng-Qiang Tong 18. Cyclodextrins as Chiral Selectors in Capillary Electrophoresis Enantioseparations Gerhard K.E. Scriba and Pavel Jac 19. Application of Dual Cyclodextrin-Systems in Capillary Electrophoresis Enantioseparations Anne-Catherine Servais and Marianne Fillet 20. Enantioseparation by Capillary Electrophoresis Using Cyclodextrins in an Amino Acid-Based Ionic Liquid Running Buffer Joachim Wahl and Ulrike Holzgrabe 21. Enantioseparations in Nonaqueous Capillary Electrophoresis Using Charged Cyclodextrins Anne-Catherine Servais and Marianne Fillet 22. Chiral Separation by NACE Using Polyol Derivative-Boric Acid Complexes Lijuan Wang, Xu Hou, Fan Zhang, Ying Liu, Yimeng Ren, and Hongyuan Yan 23. Chiral Capillary Electrophoresis-Mass Spectrometry Maria Castro-Puyana and Maria Luisa Marina 24. Enantioseparation of Selected Imidazole Drugs Using Dual Cyclodextrin-Modified Micellar Electrokinetic Chromatography Wan Aini Wan Ibrahim, Siti Munirah Abd Wahib, Dadan Hermawan, and Mohd Marsin Sanagi 25. Carbohydrate-Based Polymeric Surfactants for Chiral Micellar Electrokinetic Chromatography (CMEKC) Coupled to Mass Spectrometry Vijay Patel and Shahab A. Shamsi 26. Application of a (18-Crown-6)-2,3,11,12-Tetracarboxylic Acid-Based Chiral Stationary Phase in Capillary Electrochromatography Wonjae Lee, Kyung Tae Kim, and Jong Seong Kang 27. Experimental Design Methodologies for the Optimization of Chiral Separations: An Overview Luiz Carlos Klein-Junior, Debby Mangelings, and Yvan Vander Heyden

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