Autophagy and senescence in cancer therapy

著者

書誌事項

Autophagy and senescence in cancer therapy

edited by David A. Gewirtz, Paul B. Fisher

(Advances in cancer research / serial editors, Kenneth D. Tew, Paul B. Fisher, v. 150)

Academic Press, an imprint of Elsevier, 2021

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注記

Includes bibliographical references

内容説明・目次

内容説明

Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more.

目次

1.Autophagy and senescence in cancer therapy Nipa H. Patel, Sarah Bloukh, Enas Alwohosh, Ahmad Alhesa, Tareq Saleh, and David A. Gewirtz 2. Targeting the stress support network regulated by autophagy and senescence for cancer treatment Jaejin Kim, Yeonghyeon Lee, Kyeonghwan Roh, Mi-Sung Kim, and Chanhee Kang 3. Autophagy and senescence, converging roles in pathophysiology as seen through mouse models Andrew R.J. Young, Liam D. Cassidy, and Masashi Narita 4. Autophagy and senescence: Insights from normal and cancer stem cells Sarmistha Talukdar, Swadesh K. Das, Luni Emdad, and Paul B. Fisher 5. The role of autophagy in escaping therapy-induced polyploidy/senescence Magdalena Dudkowska, Karolina Staniak, Agnieszka Bojko, and Ewa Sikora 6. Autophagy and PTEN in DNA damage-induced senescence Arishya Sharma and Alexandru Almasan 7. Cellular senescence and tumor promotion: Role of the Unfolded Protein Response Olivier Pluquet and Corinne Abbadie 8. mTOR as a senescence manipulation target: A forked road Sarah Saoudaoui, Monique Bernard, Guillaume B. Cardin, Nicolas Malaquin, Apostolos Christopoulos, and Francis Rodier

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