Chiral ligands : evolution of ligand libraries for asymmetric catalysis
Author(s)
Bibliographic Information
Chiral ligands : evolution of ligand libraries for asymmetric catalysis
（New directions in organic and biological chemistry）
CRC Press, 2021
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Note
Includes index
Includes bibliographical references and index
Description and Table of Contents
Description
Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.
Key Features:
The book presents historical content from the time of discovery for each family of ligands.
Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactions
Suitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable production
Edited by a distinguished scientist in the field, the book has a diverse audience including research groups in homogeneous catalysis, particularly asymmetric transformations
Table of Contents
Contents
Preface......................................................................................................................vii
Editor.........................................................................................................................ix
List of Contributors....................................................................................................xi
Abbreviations and Acronyms................................................................................. xiii
Chapter 1 Chiral Bidentate Heterodonor P-Oxazoline Ligands ...........................1
Maria Biosca, Jordi Faiges, Montserrat Dieguez,
and Oscar Pamies
Chapter 2 Chiral Bidentate Heterodonor P-N-Other-Ligands............................. 33
Pep Rojo, Marina Bellido, Xavier Verdaguer, and Antoni Riera
Chapter 3 Chiral Bidentate Heterodonor P,S/O Ligands..................................... 81
Jessica Margalef and Miquel A. Pericas
Chapter 4 Chiral Bidentate Heterodonor P-P' ligands....................................... 109
Antonio Pizzano
Chapter 5 Chiral Tridentate-Based Ligands...................................................... 167
Uchchhal Bandyopadhyay, Basker Sundararaju, Rinaldo Poli,
and Eric Manoury
Chapter 6 Chiral N-Heterocyclic Carbene-Based Ligands................................ 195
Vincent Cesar, Christophe Fliedel, and Agnes Labande
Chapter 7 Chiral Monophosphorus Ligands...................................................... 233
Wenjun Tang, Feng Wan, and He Yang
Chapter 8 Solvent-Oriented Ligand and Catalyst Design in Asymmetric
Catalysis - Principles and Limits ..................................................... 261
Armin Boerner
Index....................................................................................................................... 315
by "Nielsen BookData"
