Handbook of nuclear medicine and molecular imaging for physicists

著者

    • Ljungberg, Michael

書誌事項

Handbook of nuclear medicine and molecular imaging for physicists

edited by Michael Ljungberg

（Series in medical physics and biomedical engineering）

CRC Press, 2022

  • : set
  • 2

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注記

Content Type: text (rdacontent), Media Type: unmediated (rdamedia), Carrier Type: volume (rdacarrier)

Includes bibliographical references

収録内容

  • volume 2. Modelling, dosimetry and radiation, protection

内容説明・目次

巻冊次

2 ISBN 9781138593299

内容説明

Mathematical modelling is an important part of nuclear medicine. Therefore, several chapters of this book have been dedicated towards describing this topic. In these chapters, an emphasis has been put on describing the mathematical modelling of the radiation transport of photons and electrons, as well as on the transportation of radiopharmaceuticals between different organs and compartments. It also includes computer models of patient dosimetry. Two chapters of this book are devoted towards introducing the concept of biostatistics and radiobiology. These chapters are followed by chapters detailing dosimetry procedures commonly used in the context of diagnostic imaging, as well as patient-specific dosimetry for radiotherapy treatments. For safety reasons, many of the methods used in nuclear medicine and molecular imaging are tightly regulated. Therefore, this volume also highlights the basic principles for radiation protection. It discusses the process of how guidelines and regulations aimed at minimizing radiation exposure are determined and implemented by international organisations. Finally, this book describes how different dosimetry methods may be utilized depending on the intended target, including whole-body or organ-specific imaging, as well as small-scale to cellular dosimetry. This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

目次

Contents Preface...............................................................................................................................vii Editor..................................................................................................................................ix Contributors.......................................................................................................................xi Chapter 1 Introduction to Biostatistics..........................................................................1 Johan Gustafsson and Markus Nilsson Chapter 2 Radiobiology....................................................................................................17 Lidia Strigari and Marta Cremonesi Chapter 3 Diagnostic Dosimetry.............................................................................................33 Lennart Johansson and Martin Andersson Chapter 4 Time- activity Curves: Data, Models, Curve Fitting, and Model Selection..........................69 Gerhard Glatting Chapter 5 Tracer Kinetic Modelling and Its Use in PET Quantification..............................................83 Mark Lubberink and Michel Koole Chapter 6 Principles of Radiological Protection in Healthcare..........................................................101 Soren Mattsson Chapter 7 Controversies in Nuclear Medicine Dosimetry..................................................................115 Michael G. Stabin Chapter 8 Monte Carlo Simulation of Photon and Electron Transport in Matter..............................123 Jose M. Fernandez- Varea Chapter 9 Patient Models for Dosimetry Applications..........................................................141 Michael G. Stabin Chapter 10 Patient- specific Dosimetry Calculations.............................................................155 Manuel Bardies, Naomi Clayton, Gunjan Kayal, and Alex Vergara Gil Chapter 11 Whole- body Dosimetry..................................................169 Jonathan Gear Chapter 12 Personalized Dosimetry in Radioembolization........................................................................................183 Remco Bastiaannet and Hugo W.A.M. de Jong Chapter 13 Thyroid Imaging and Dosimetry..........................................................................207 Michael Lassmann and Heribert Hanscheid Chapter 14 Bone Marrow Dosimetry........................................................................................223 Cecilia Hindorf Chapter 15 Cellular and Multicellular Dosimetry...................................................................235 Roger W. Howell Chapter 16 Alpha- particle Dosimetry................................................................267 Stig Palm Chapter 17 Staff Radiation Protection........................................................................275 Lena Jonsson Chapter 18 IAEA Support to Nuclear Medicine...........................................................293 Gian Luca Poli
巻冊次

: set ISBN 9781138593350

内容説明

This state-of-the-art set of handbooks provides medical physicists with a comprehensive overview of the field of nuclear medicine. In addition to describing the underlying, fundamental theories of the field, it includes the latest research and explores the practical procedures, equipment, and regulations that are shaping the field and it's future. This set is split into three volumes, respectively titled: Instrumentation and Imaging Procedures; Modelling, Dosimetry and Radiation Protection; and Radiopharmaceuticals and Clinical Applications. Volume one, Instrumentation and Imaging Procedures, focuses primarily on providing a comprehensive review into the detection of radiation, beginning with an introduction to the history of nuclear medicine to the latest imaging technology. Volume two, Modelling, Dosimetry and Radiation Protection, explores the applications of mathematical modelling, dosimetry, and radiation protection in nuclear medicine. The third and final volume, Radiopharmaceuticals and Clinical Applications, highlights the production and application of radiopharmaceuticals and their role in clinical nuclear medicine practice. These books will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

目次

Volume I: Instrumentation and Images Processing. 1. The History of Nuclear Medicine 2. Basics of Nuclear Physics 3. Basics of Radiation Interaction in Matter 4. Radionuclide Production 5. Radiometry 6. Scintillation Detectors 7. Semiconductor Detectors 8. Gamma Spectroscopy 9. Properties of the Digital Image 10. Digital Image Processing 11. Machine-Learning 12. Image File Structures in Nuclear Medicine 13. The Scintillation Camera 14. Collimators for Gamma Ray Imaging 15. Image Acquisition Protocols 16. Single Photon Emission Computed Tomography (SPECT) and SPECT/CT Hybrid Imaging 17. Dedicated Tomographic Single Photon Systems 18. Positron Emission Tomography (PET) 19. Dead Time Effects in Nuclear Medicine Imaging Studies 20. Principles of Iterative Reconstruction for Emission Tomography 21. Clinical Molecular PET/CT Hybrid Imaging 22. Clinical Molecular PET/MRI Hybrid Imaging 23. Quality Assurance of Nuclear Medicine Systems 24. Calibration and Traceability 25. Activity Quantification from Planar images 26. Quantitation in Emission Tomography 27. Multicenter studies: Hardware and Software Requirements 28. Pre-Clinical Molecular Imaging Systems 29. Monte Carlo simulations of Nuclear Medicine Imaging Systems 30. Beta and Alpha Particle Autoradiography 31. Principles behind Computed Tomography (CT) 32. Principles behind Magnetic Resonance Imaging (MRI) Volume II: Dosimetry and Radiation Protection . 1. Introduction to Biostatistics 2. Radiobiology 3. Diagnostic Dosimetry 4. Time-Activity Curves: Data, Models, Curve Fitting and Model Selection 5. Tracer Kinetic Modelling and its use in PET Quantification 6. Principles of Radiological Protection in Healthcare 7. Controversies in Nuclear Medicine Dosimetry 8. Monte Carlo Simulation of Photon and Electron Transport in Matter 9. Patient Models for Dosimetry Applications 10. Patient-Specific Dosimetry Calculations 11. Whole Body Dosimetry 12. Personalized Dosimetry in Radioembolization 13. Thyroid Imaging and Dosimetry 14. Bone Marrow Dosimetry 15. Cellular and Multicellular Dosimetry 16. Alpha-Particle Dosimetry 17. Staff Radiation Protection 18. IAEA support to Nuclear Medicine Volume III: Radiopharmaceuticals and Clinical Applications. 1. Principles behind Radiopharmacy 2. Radiopharmaceuticals for diagnostics: Planar/SPECT 3. Radiopharmaceuticals for diagnostics: PET 4. Radiopharmaceuticals for radionuclide therapy 5. Design Considerations for a Radiopharmaceutical Production Facility 6. Methods and Equipment for Quality Control of Radiopharmaceuticals 7. Environmental Compliance and Control for Radiopharmaceutical Production: Commercial Manufacturing and Extemporaneous Preparation 8. GMP - rules and recommendations 9. Management of Radioactive Waste in Nuclear Medicine 10. Translation of Radiopharmaceuticals: Mouse to Man 11. Radionuclide Bone Scintigraphy 12. Radionuclide Examinations of the Kidneys 13. Neuroimaging in Nuclear Medicine 14. Methodology and Clinical Implementation of Ventilation/Perfusion Tomography for Diagnosis and Follow-up of Pulmonary Embolism and Other Pulmonary Diseases Clinical use of hybrid V/P SPECT-CT 15. Myocardiac Perfusion Imaging 16. Infection and Inflammation 17. Special Considerations In Pediatric Nuclear Medicine 19. Antibody-Based Radionuclide Imaging 18. Radionuclide-Based Diagnosis and Therapy of Prostate Cancer 20. Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors 21. Lymphoscintigraphy 22. Diagnostic Ultrasound Tomas Jansson 23. Clinical Trials - Purpose and Procedures 24. Introduction to Patient Safety and Improvement Knowledge 25. Closing remarks

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