Oxytocin : methods and protocols
著者
書誌事項
Oxytocin : methods and protocols
(Methods in molecular biology / John M. Walker, series editor, 2384)(Springer protocols)
Humana Press, c2022
大学図書館所蔵 全1件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
This detailed book explores techniques for further elucidating the peripheral and central roles of oxytocin as well as techniques key to oxytocin receptor-related drug discovery. The first set of chapters explore this neuropeptide's peripheral and central effects, such as regulation of myometrial contraction, induction of cardioprotective effects, and the facilitation of pro-social behaviors. The book then continues by delving into a comprehensive pharmacological characterization of oxytocin receptor ligands and ligands of other key receptors such as the vasopressin receptor family. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Oxytocin: Methods and Protocols is an ideal guide for researchers seeking to further our knowledge of the varied and power effects of oxytocin within the central nervous system.
目次
1. The Importance of Experimental Investigation of the Peripheral Oxytocin System
Stephen J. Assinder
2. Human Myometrial Contractility Assays
Sarah Arrowsmith
3. The Effect of Oxytocin on Intracellular Ca2+ Release in Cardiac Cells
Anatoliy Shmygol, Sanaa H.S.H. Alameri, Khadeijah Y.K.M. Almemari, Naema M.A.J. Alsuwaidi, and Ifrah I. Ali
4. The Importance of Experimental Investigation of the CNS Oxytocin System
Kelsie A. Boulton and Adam J. Guastella
5. The Role of Oxytocin in Social Circuits and Social Behavior in Dementia
Olivier Piguet, Rebekah M. Ahmed, and Fiona Kumfor
6. Evaluating Methylation of the Oxytocin Receptor Gene and the Oxytocin Intergenic Region
Leonora King, Stephanie Robins, Gary Chen, Gustavo Turecki, and Phyllis Zelkowitz
7. Using Receptor Autoradiography to Visualize and Quantify Oxytocin and Vasopressin 1a Receptors in the Human and Nonhuman Primate Brain
Sara M. Freeman
8. Linking Central Gene Expression Patterns and Mental States Using Transcriptomics and Large-Scale Meta-Analysis of fMRI Data: A Tutorial and Example Using the Oxytocin Signaling Pathway
Jaroslav Rokicki, Daniel S. Quintana, and Lars T. Westlye
9. CRISPR/Cas9-Mediated Genetic Engineering to Generate a Disease Model Prairie Vole, Based on the Species-Optimized Assisted Reproductive Technology
Kengo Horie and Katsuhiko Nishimori
10. The Current Status of Drug Discovery for the Oxytocin Receptor
Philippe E. Nashar, Aidan Whitfield, Jiri Mikusek, and Tristan A. Reekie
11. Fmoc Solid Phase Peptide Synthesis of Oxytocin and Analogues
Thomas Kremsmayr and Markus Muttenthaler
12. Employing the Operational Model to Measure System-Independent OTR Efficacy
Kiyan Afzali and Mark Connor
13. Use of BRET to Measure -Arrestin Recruitment at Oxytocin and Vasopressin Receptors
Edin Muratspahic, Jasmin Gattringer, and Christian W. Gruber
14. Measuring Affinity of Ligands to the Oxytocin Receptor Using Radioligand Binding
Eryn L. Werry and Michael Kassiou
15. Use of Co-Cultures to Measure the Blood-Brain Barrier Permeability of Oxytocin
Yasuhiko Yamamoto, Ai Harashima, Sei-ichi Munesue, and Haruhiro Higashida
16. Intracerebral Delivery of an OTR Antagonist and Subsequent Behavioral Testing in Prairie Voles
Yu Hirota, Chisato Otsuki, Erika Kamura, and Shinichi Mitsui
「Nielsen BookData」 より