Essentials of laboratory animal science : principles and practices
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Essentials of laboratory animal science : principles and practices
Springer, c2021
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Includes bibliographical references
Description and Table of Contents
Description
This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.
Table of Contents
Chapter 1. Introduction to Laboratory Animal Medicine. -Chapter 2. Policies, Principles and regulations Governing the Care and Use of Animal in India. -Chapter 3. Ethics and Animal welfare. -Chapter 4. Designing of Lab animal facilities. -Chapter 5. Quality control of Laboratory animals. -Chapter 6. Biostatistics and design of experiments in Laboratory animal science. -Chapter 7. Alternatives to animal models. -Chapter 8. Anatomy, Physiology and husbandry - Mice and Rat. -Chapter 9. Anatomy, Physiology and Husbandry - Rabbits and Guinea Pigs. -Chapter 10. Genetics and Breeding of Laboratory animals. -Chapter 11. Nutrition and feeding in Laboratory animals. -Chapter 12. Microbiology and infectious diseases of Laboratory animals. -Chapter 13. Pathology of infectious and non-infectious diseases affecting Laboratory animals. -Chapter 14. Behaviour of laboratory animals. -Chapter 15. Drug administration and collection of blood in rodents and rabbits. -Chapter 16. Clinical examination of Rodents and Rabbits. -Chapter 17. Anaesthesia, Analgesia and euthanasia in Rodents and Rabbits. -Chapter 18. Techniques of animal experimentation: Surgical animal models and Non-invasive techniques. -Chapter 19. Bio safety consideration in Lab animal facilities and working on infectious agents. -Chapter 20. Histology, Systemic Dissection and Necropsy Techniques, organ collection in Laboratory animals. -Chapter 21. Occupational health hazards and disaster management in lab animal facility. -Chapter 22. Imaging modalities for preclinical research. -Chapter 23. Efficacy studies pathology scoring and digital image analysis of histopathology Images.
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