CRISPR genome surgery in stem cells and disease tissues

著者

    • Tsang, Stephen H.

書誌事項

CRISPR genome surgery in stem cells and disease tissues

edited by Stephen H. Tsang

Academic Press, an imprint of Elsevier, c2022

  • : [pbk.]

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature.

目次

1. History of CRISPR 2. Different Kinds of CRISPR (SpCas9, CjCas9, CaCas9, etc.) 3. Genome engineering in iPSC cells 4. CRISPR manipulations in stem cell lines for neurological diseases 5. Gene editing for the cornea 6. CRISPR screening for eye diseases 7. Employing Non-homologous End Joining and Homology-directed Repair for Treatment of Leber Congenital Amaurosis and Retinal Degeneration 8. Ethics of Gene Editing in Human Stem Cells 9. sGRNA 10. CRISPR vs ZFN/TALEN

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詳細情報

  • NII書誌ID(NCID)
    BC11195486
  • ISBN
    • 9780128178768
  • 出版国コード
    uk
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    London
  • ページ数/冊数
    ix, 126 p.
  • 大きさ
    24 cm
  • 分類
  • 件名
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