Gene delivery : nanotechnology and therapeutic applications

Author(s)

    • Pathak, Yashwant

Bibliographic Information

Gene delivery : nanotechnology and therapeutic applications

edited by Yashwant Pathak

(Drugs and the pharmaceutical sciences)

CRC Press, 2022

  • : hbk

Available at  / 2 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers. Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene therapy and gene delivery. Written by prominent authors in the field, this book covers various aspects of gene delivery including challenges in delivering gene therapy, advances in genome editing, RNA-based gene therapy, Green nanoparticles for oligonucleotide delivery. Additional features include" Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing. Includes knowledge of the current application of CRISPR/Cas9 gene-editing technique; an approach that has recently been given the Noble Prize. Examines the development of mRNA vaccines for Covid -19 in challenging pandemic scenario Discusses siRNA, mRNA, and DNA plasmids.

Table of Contents

Chapter 01 Challenges in delivering gene therapy Chapter 02 Advances in genome editing: the technology of choice for precise and efficient disease treatment, with special focus on nano delivery systems Chapter 03 Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy Chapter 04 Green nanoparticles for oligonucleotide delivery Chapter 05 Development of mRNA vaccines for Covid -19 in challenging Pandemic scenario Chapter 06 Gene therapy for cardiovascular diseases: clinical evidences Chapter 07 Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS Chapter 08 siRNA delivery for therapeutic applications using nanoparticles Chapter 09 Clinical perspectives on Gene therapy for retina and eye diseases Chapter 10 Herpesvirus microRNAs for use in gene therapy immune-evasion strategies Chapter 11 siRNA delivery for therapeutic applications using nanoparticles Chapter 12 Gene therapy and small molecule treatment for cystic fibrosis Chapter 13 CRISPR gene therapy recent trends and clinical applications Chapter 14 Clinical applications of gene therapy for Immuno-deficiencies Chapter 15 Regulatory challenges for nano gene delivery

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