Macropinocytosis : functions and mechanisms

著者

    • Commisso, Cosimo

書誌事項

Macropinocytosis : functions and mechanisms

Cosimo Commisso, Editor

(Subcellular biochemistry, v. 98)

Springer, c2022

  • : hbk

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students.

目次

Table of Contents Macropinocytosis - Functions and Mechanisms Preface Part 1: Functions of Macropinocytosis1. Functional Diversity of Macropinocytosis - Mishra et al. 2. Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathways - Lambies et al.3. The amoebal model for micropinocytosis - Kay et al.4. Extracellular ATP and macropinocytosis - Evers et al.5. Macropinocytosis and Cell Migration: Don't drink an drive - Delgado et al. 6. Macropinocytosis in phagocyte function and immunity - Canton et al. Part 2: Signaling Mechanisms Driving Macropinocytosis7. Roles of 3' Phosphoinositides in Macropinocytosis - Swanson et al.8. Signaling pathways that regulate macropinocytosis in mammalian cells - Palm9. Wnt, GSK3 and Macropinocytosis - Munoz et al.10. Kras addiction promotes cancer cell adapation in harsh microenvironment through micropinocytosis - Seguin et al. 11. Kras-independent macropinocytosis in pancreatic cancer - Hobbs et al.

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詳細情報

  • NII書誌ID(NCID)
    BC12599549
  • ISBN
    • 9783030940034
  • 出版国コード
    sz
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    Cham
  • ページ数/冊数
    xi, 224 p.
  • 大きさ
    25 cm
  • 分類
  • 件名
  • 親書誌ID
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