Fundamentals of preparative and nonlinear chromatography

Author(s)

Bibliographic Information

Fundamentals of preparative and nonlinear chromatography

Georges Guiochon, Attila Felinger, Dean G. Shirazi, Anita M. Katti

Elsevier Academic Press, c2006

2nd ed

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Description and Table of Contents

Description

Fundamentals of Preparative and Nonlinear Chromatography, Second Edition is devoted to the fundamentals of a new process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography. This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography. It presents the models used in chromatography and their solutions, discusses the applications made, describes the different processes used, their numerous applications, and the methods of optimization of the experimental conditions of this process.

Table of Contents

1. Introduction, Definitions, Goal 2. The Mass Balance Equation of Chromatography and Its General Properties 3. Single-Component Equilibrium Isotherms 4. Competitive Equilibrium Isotherms 5. Transfer Phenomena in Chromatography 6. Linear Chromatography 7. Band Profiles of Single-Components with the Ideal Model 8. Band Profiles of Two Components with the Ideal Model 9. Band Profiles in Displacement Chromatography with the Ideal Model 10. Single- Component Profiles with the Equilibrium Dispersive Model 11. Two-Component Band Profiles with the Equilibrium-Dispersive Model 12. Frontal Analysis, Displacement and the Equilibrium-Dispersive Model 13. System Peaks with the Equilibrium-Dispersive Model 14. Kinetic Models and Single-Component Problems 15. Gradient Elution Chromatography under Nonlinear Conditions 16. Kinetic Models and Multicomponent Problems 17. Simulated Moving Bed Chromatography 18. Optimization of the Experimental Conditions

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Details

  • NCID
    BC13213964
  • ISBN
    • 9780123705372
  • LCCN
    94015955
  • Country Code
    us
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Original Language Code
    eng
  • Place of Publication
    San Diego
  • Pages/Volumes
    xiv, 975 p.
  • Size
    26 cm
  • Classification
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