From obesity to diabetes
Author(s)
Bibliographic Information
From obesity to diabetes
(Handbook of experimental pharmacology, 274)
Springer, c2022
Available at 2 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Includes bibliographical references
Description and Table of Contents
Description
Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
Table of Contents
Part I Obesity. Epidemiology of Obesity.- The Circadian Clock and Obesity.- Nutrition and Microbiome.- From Obesity to Diabetes: The Role of the Adipose Organ.- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy.- The Enteroendocrine System in Obesity.- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches.- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction.- Obesity, Senescence, and Senolytics.- Obesity and Obstructive Sleep Apnea.- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance.- Islet Inflammation and Cell Dysfunction in Type 2 Diabetes.- NAFLD and NASH: The Metabolically Diseased Liver.- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities.- Diabetic Peripheral Neuropathy.- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies.- Physical Activity, Obesity and Weight Loss Maintenance.- Bariatric/Metabolic Surgery.- Drugs for Treating Obesity.- Novel Drugs for Diabetes Therapy.- Novel Approaches to Restore Pancreatic Beta-Cell Mass
and Function.- Precision Medicine and Obesity.- Targeting the Enteroendocrine System for Treatment of Obesity.
by "Nielsen BookData"