In silico systems biology
著者
書誌事項
In silico systems biology
（Methods in molecular biology / John M. Walker, series editor, 1021）（Springer protocols）
Humana Press, c2013
- : [hardback]
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Systems biology can now be considered an established and fundamental field in life sciences. It has moved from the identification of molecular 'parts lists' for living organisms towards synthesising information from different 'omics'-based approaches to generate and test new hypotheses about how biological systems work. In In Silico Systems Biology: Methods and Protocols, expert researchers in the field detail a practical set of chapters based often on actual materials used and develop for face-to-face training with examples and case studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step workflows, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, In Silico Systems Biology: Methods and Protocols seeks to aid scientists in the further study of network biology and mathematical models of biological systems.
目次
1. Defining Systems Biology: A Brief Overview of the Term and Field
Maria Victoria Schneider
2. Approaches to Modelling Gene Regulatory Networks - A Gentle Introduction Thomas Schlitt
3. Integration of Genomic Information with Biological Networks using Cytoscape
Anna Bauer-Menren
4. Visualization and Analysis of Biological Networks
Pablo Porras Millan
5. Modeling Signaling Networks with Different Formalisms: A Preview
Aidan MacNamara, David Henriques, and Julio Saez-Rodriguez
6. From a Biological Hypothesis to the Construction of a Mathematical ModelDavid Cohen, Inna Kuperstein, Emmanuel Barillot, Andrei Zinovyev and Laurence Calzone
7. Practical use of BiNoM, a Biological Network Manager Software
Eric Bonnet, Laurence Calzone, Daniel Rovera, Gautier Stoll, Emmanuel Barillot, and Andrei Zinovyev
8. Using Chemical Kinetics to Model Biochemical Pathways
Nicolas Le Novere and Lukas Endler
9. Simulation of Stochastic Kinetic
Models
Andrew Golightly and Colin S. Gillespie
10. BioModels Database: A Repository of Mathematical Models of Biological Processes
Vijayalakshmi Chelliah, Camille Laibe, and Nicolas Le Novere
11. Supporting SBML as a Model Exchange Format in Software
Applications
Sarah M. Keating and Nicolas Le Novere
12. Controlled Annotations for Systems Biology
Nick Juty, Camille Laibe, and Nicolas Le Novere
13. Bayesian Approaches for Mechanistic
Ion Channel Modelling
Ben Calderhead, Michael Epstein, Lucia Sivilotti, Mark Girolami
14. Building Models using Reactome Pathways as Templates
David Croft
15. Uniform Curation Protocol of Metazoan Signaling Pathways to Predict Novel Signaling Components
Mate Palfy, Illes J. Farkas, Tibor Vellai, and Tamas Korcsmaros
16. Bioinformatics Workflows and Web-services in Systems Biology Made Easy for Experimentalists
Rafael C. Jimenez and Manuel Corpas
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