Regulation of downstream targets

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Bibliographic Information

Regulation of downstream targets

edited by Rossen Donev

(Advances in protein chemistry and structural biology, v. 134)

Academic Press, an imprint of Elsevier, 2023

Available at  / 8 libraries

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Includes bibliographical references

Description and Table of Contents

Description

Regulation of Downstream Targets, Volume 134 in the Advances in Protein Chemistry and Structural Biology series, presents interesting chapters on topics such as Transcriptional regulatory mechanisms and signaling networks in Viral Infections, Identification of potential key genes associated with pathogenesis and prognosis of endometrial cancer based on Integrated Bioinformatics Approaches, Differential regulation of genes in stage IB pancreatic cancer associated with increased risk of metastasis, AMPK-related LKB1-downstream targets, A compilation of bioinformatic approaches to identify novel downstream targets for the detection and prophylaxis of cancer, Protein phosphatases and their targets: Critical determinants of signaling pathway in plants, and more. Other sections cover Calcium decoders and their targets: The holy alliance that regulate cellular responses, Importin alpha family NAAT/IBB domain: functions of a multi-faceted long chameleon sequence, Aurora Kinase A and related downstream molecules: A Potential Network for Cancer Therapy, Emerging Role of Heat Shock Proteins in Cardiovascular Diseases, Function, Structure, Evolution, Regulation and Drug Target Relevance of Arylalkylamine N-acetyltransferase, and Analysis of signaling cascades from myeloma cells treated with pristimerin.

Table of Contents

1. Transcriptional regulatory mechanisms and signaling networks in cancer Chandrabose Selvaraj, Karthik Raja Ramalingam, Devadasan Velmurugan, and Sanjeev Kumar Singh 2. Identification of dysregulated canonical pathways associated with pathogenesis and progression of Amyotrophic Lateral Sclerosis-An integrated bioinformatics approach Ankur Datta, S. Udhaya Kumar, Maria D'costa, Anusha Bothe, D. Thirumal Kumar, Hatem Zayed, and C. George Priya Doss 3. Elucidating the mechanism of antimicrobial resistance in Mycobacterium tuberculosis using gene interaction networks Keerthana G., Karthick Vasudevan, Hrituraj Dey, Tasmia Kausar, S. Udhaya Kumar, D. Thirumal Kumar, Hatem Zayed, and C. George Priya Doss 4. AMPK-like proteins and their function in female reproduction and gynecologic cancer Claire Baumgartner, Anil Kumar Yadav, and Ilana Chefetz 5. A compilation of bioinformatic approaches to identify novel downstream targets for the detection and prophylaxis of cancer Mangala Hegde, Sosmitha Girisa, and Ajaikumar B. Kunnumakkara 6. Protein phosphatases and their targets: Comprehending the interactions in plant signaling pathways Lokesh K. Saini, Malathi Bheri, and Girdhar K. Pandey 7. Calcium decoders and their targets: The holy alliance that regulate cellular responses in stress signaling Barkha Ravi, Sibaji K. Sanyal, and Girdhar K. Pandey 8. Importin alpha family NAAT/IBB domain: Functions of a pleiotropic long chameleon sequence Kazuya Jibiki, Takashi S. Kodama, and Noriko Yasuhara 9. AURORA KINASE A and related downstream molecules: A potential network for cancer therapy Homa Fatma, and Hifzur R. Siddique 10. Emerging role of heat shock proteins in cardiovascular diseases Joyita Hazra, Anupama Vijayakumar, and Nitish R. Mahapatra 11. Function, structure, evolution, regulation of a potent drug target, arylalkylamine N-acetyltransferase Lei Zhang, Yu Tang, David J. Merkler, and Qian Han 12. Analysis of signaling cascades from myeloma cells treated with pristimerin Heba Almaghrbi, Rehab Elkardawy, S. Udhaya Kumar, Shilpa Kuttikrishnan, Taghreed Abunada, Manoj Kumar Kashyap, Aamir Ahmad, Shahab Uddin, C. George Priya Doss, and Hatem Zayed 13. Mixed lineage kinase domain-like pseudokinase: Conventional (necroptosis) and unconventional (necroptosisindependent) functions and features Tuna Onal, Melike Ozgul-Onal, and Ilana Chefetz

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