Macro-glycoligands : methods and protocols
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Macro-glycoligands : methods and protocols
（Methods in molecular biology, 1367）（Springer protocols）
Springer , Humana Press, c2016
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume details methods and protocols for the synthesis and characterization of glycopolymers and their biomedical applications. Chapters are divided into three parts covering synthesis and characterization of glycopolymers; glycopolymer-nanoparticle conjugates; and surface immobilized glycopolymers. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Macro-Glycoligands: Methods and Protocols aims to ensure successful results in the further study of this vital field.
目次
Part I: Synthesis and Characterization of Glycopolymers
1. Synthesis of Chain-end Functionalized Glycopolymers via Cyanoxyl Mediated Free Radical Polymerization (CMFRP)
Valentinas Gruzdys, Jinshan Tang, Elliot Chaikof, Xue-Long Sun
2. Protecting-group-free Synthesis of Well-defined Glycopolymers Featuring Negatively Charged Oligosaccharides
Luca Albertin
3. Glycopolymers Prepared by Ring-opening Metathesis Polymerization Followed by Glycoconjugation Using a Triazole Forming 'Click' Reaction
Ronald Okoth and Amit Basu
4. Protecting-group-free Synthesis of Glycopolymers and Their Binding Assay with Lectin and Influenza Virus
Tomonari Tanaka, Tadanobu Takahashi, and Takashi Suzuki
5. Carbohydrate-based Initiators for the Cationic Ring-opening Polymerization of 2-Ethyl-2-oxazoline
Christine Weber,Michael Gottschaldt, Richard Hoogenboom, Ulrich S. Schubert
6. Heterofunctional Glycopolypeptides by Combination of Thiol-ene Chemistry and NCA Polymerization
Kai-Steffen Krannig and Helmut Schlaad
7. Preparation of Proteoglycan Mimetic Graft Copolymers
Matt J. Kipper and Laura W. Place
Part II: Glycopolymer Nanoparticle Conjugates
8. Galactosylated Polymer Nano-objects by Polymerization-Induced Self-Assembly, Potential Drug Nanocarriers
Mona Semsarilar, Irene Canton, and Vincent Ladmiral
9. Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical Applications
Christian K. Adokoh, James Darkwa, and Ravin Narain
10. Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer using Thiol-Halogen Click Chemistry
Wentao Song and Anthony M. Granville
11. Glycopolymer-grafted Polymer Particles for Lectin Recognition
Michinari Kohri, Tatsuo Taniguchi, and Keiki Kishikawa
12. Synthesis of Non-spherical Glycopolymer-decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry
Xiao Li, Weidong Zhang,and Gaojian Chen
13. Synthetic Approach To Glycopolymer Base Nanoparticle Gold(I) Conjugate: A New Generation Of Therapeutic Agents
Christian K. Adokoh, James Darkwa, and Ravin Narain
14. Multivalent Glycopolymer-coated Gold Nanoparticles
Sarah-Jane Richards, Caroline I. Biggs, and Matthew I. Gibson
Part III: Surface Immobilized Glycopolymers
15. Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry
Kai Yu, A. Louise Creagh, Charles A. Haynes, Jayachandran N. Kizhakkedathu
16. Oriented Immobilized Sialyloligo-Macroligand Microarray
Satya Nandana Narla and Xue-Long Sun
17. Glycocalyx Remodeling with Glycopolymer-based Proteoglycan Mimetics
Mia L. Huang, Raymond A. A. Smith, Greg W. Trieger, and Kamil Godula
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