The guinea pig model : an alternative method for vaccine potency testing

Author(s)

    • Parreño, Viviana

Bibliographic Information

The guinea pig model : an alternative method for vaccine potency testing

Viviana Parreño

(Pocket guides to biomedical sciences / series editor, Dongyou Liu)

CRC Press/Taylor & Francis Group, 2023

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Includes bibliographical references and index

Description and Table of Contents

Description

This book summarizes the development and statistical validation of a guinea pig model as an alternative for potency testing of the viral antigens included in combined vaccines applied in cattle to control the respiratory, reproductive, and neonatal calf diarrhea syndromes. The model allows, in one serum sample, to test the vaccine quality for all the viral antigens included in aqueous as well as in oil-adjuvanted formulations of bovine vaccines. The methodology proposed for the control of bovine herpes virus, parainfluenza, and rotavirus were recommended by CAMEVET as guidelines for the 30 countries in the forum, including the US. Key Features Reviews combined vaccines used for cattle Summarizes animal models used for vaccine testing Focuses on bovine herpesviruses, rotaviruses, parainfluenza, and bovine viral diarrhea virus Provides guidance on the effectiveness of the Guinea Pig model for testing vaccine immunogenicity

Table of Contents

Chapter 1 - Vaccination of cattle Chapter 2 - Guinea pig model to test the potency of IBR vaccines Chapter 3 - Guinea pig model to test the potency of Rotavirus vaccines Chapter 4 - Guinea pig model to test the potency of Bovine Parainfluenza Type 3 Virus vaccines Chapter 5 - Guinea pig model to test the potency of BVDV vaccines Chapter 6 - Guinea pig model application References

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