MーCSFによる粥状動脈硬化症治療の試み
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MーCSFによる粥状動脈硬化症治療の試み
山田信博, 1993
- Title Transcription
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M-CSF ニヨル カユジョウ ドウミャク コウカショウ チリョウ ノ ココロミ
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研究分担者 : 島野仁,後藤田貴也,原田賢治,渡辺嘉郎
論文執筆者 : 高久文磨,矢崎義雄,齋藤康,吉田尚,岡輝明,渡邊嘉雄
平成4年度科学研究費補助金(試験研究(B)1)研究成果報告書(研究課題番号02557110)
Contents of Works
- Human monocyte clony-stimulating factor enhances the clearance of lipoproteins containing apolipoprotein B-100 via both low density lipoprotein receptor-dependent and -independent pathways in rabbits
- Monocyte colony-stimulating factor enhances uptake and degradation of acetylated low density lipoproteins and cholesterol esterification in human monocyte-derived macrophages
- Expression of M-CSF receptor encoded by c-fms on smooth muscle cells derived from arteriosclerotic lesion
- Platelet-derived growth factor induces c-fms and scavenger receptor genes in vascular smooth muscle cells
- Macrophage colony stimulating factor prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits
- Platelet-derived growth factor BB-dimer suppresses the expression of macrophage colony-stimulating factor in human vascular smooth muscle cells
- Role of monocyte colony-stimulating factor in foam cell generation