CiNii Articles - HOSHINO Tsutomu

1

P-85 Biosynthesis of a novel cyclic C_<35>-terpene by the cyclisation of a Z-type C_<35>-polyprenyl diphosphate obtained from a nonpathogenic Mycobacterium species(Poster Presentation) [in Japanese]

Sato Tsutomu , Kigawa Atsushi , Takagi Ryosuke , Adachi Tomomi , Hoshino Tsutomu

Lipid components from 12 nonpathogenic Mycobacterium species were analysed. A novel cyclic C_<35>-terpene, named heptaprenylcycline 1, was obtained from 3 species, while octahydroheptaprenol 2, …

Symposium on the Chemistry of Natural Products, symposium papers 50(0), 517-522, 2008

J-STAGE
2

4 Novel Halimane-type Diterpenes Produced by Pathogenic Mycobacterium tuberculosis : Molecular Cloning, Functional Analyses, Substrate Specificity and Biological Activity [in Japanese]

Nakano Chiaki , Okamura Tomoo , Sato Tsutomu , Hara Takashi , Dairi Tohru , Toyomasu Tomonobu , Sassa Takeshi , Hoshino Tsutomu

Based upon the genomic database of Mycobacterium tuberculosis H37Rv, the gene Rv3377c,which is a putative terpene cyclase, was amplified by PCR and ligated into BamH I/Hind III site of pET 22b(+), and …

Symposium on the Chemistry of Natural Products, symposium papers 48(0), 19-24, 2006

J-STAGE
3

オキシドスクアレン-ラノステロール環化酵素欠損型の酵母変異株の取得 [in Japanese]

SATO Tsutomu , HOSHINO Tsutomu

我々はオキシドスクアレン-ラノステロール環化酵素(OLC)の触媒機構を解明するため、酵母の発現糸を構築することを計画した。しかし、野生型の酵母は自身のOLCを持っていることから、そのまま発現宿主として用いることはできない。したがって、 OLC欠損型の酵母変異株を取得することを目的に実験を行った。酵母OLC欠損型二倍体から胞子形成を経て一倍体を分離した。得られた株(3-5-1)について、抗生物質に対 …

Bulletin of the Faculty of Agriculture,Niigata University 56(2), 113-118, 2004-03

IR JASI
4

Candida albicans由来のオキシドスクアレン-ラノステロール環化酵素の大腸菌における発現について [in Japanese]

SATO Tsutomu , HOSHINO Tsutomu

In order to investigate the catalytic mechanism of oxidosqualene-lanosterol cyclase (OLC), we have tried to construct the overexpression system of OLC from C. albicans in E. colt. First, a natural typ …

Bulletin of the Faculty of Agriculture,Niigata University 56(2), 105-112, 2004-03

IR JASI
5

スクアレン : ホペン環化酸素に保存されているフェニルアラニン残基とチロシン残基の触媒機能 [in Japanese]

佐藤努 , 星野力

Nippon Nōgeikagaku Kaishi 77(4), 430-431, 2003-04-01

J-STAGE References (3)
6

Squalene cyclase : Cyclization mechanism and creation of unnatural natural triterpenes [in Japanese]

HOSHINO Tsutomu

Nippon Nōgeikagaku Kaishi 76(12), 1187-1190, 2002-12-01

J-STAGE References (17) Cited by (1)
7

Insight into the active sites of squalene cyclase and the cyclization mechanism [in Japanese]

HOSHINO Tsutomu

Bioscience & industry 59(3), 23-26, 2001-03-01

Ichushi Web References (10)
8

46(P-3) Biosynthesis of Violacein, a Purple-colored Bacterial Pigment : Biosynthetic Mechanism and Structures of Hypothetical Intermediates [in Japanese]

Hoshino T. , Mizuoka T. , Ruhul Momen A. Z. M. , Hayashi T. , Yamamoto M.

In this symposium, we present the biosynthetic studies of violacein, a bacterial pigment colored with purplish-blue, which shows antibiotic activity, the induction of apoptosis to V79 cell-line, cytot …

Symposium on the Chemistry of Natural Products, symposium papers 43(0), 269-274, 2001

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9

34 Cyclization Mechanism of Squalene Proposed on the Basis of Site-directed Mutagenesis Experiments [in Japanese]

HOSHINO Tsutomu , SATO Tsutomu , Kouda Masanori , Ohhasi Shumi , Abe Takamasa

Squalene cyclization mechanism and the active sites of the cyclase are discussed on the basis of the site-directed mutagenesis experiments. 1. DXDDTA motif: the initiation of the polycyclization and s …

Symposium on the Chemistry of Natural Products, symposium papers 41(0), 199-204, 1999

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10

25 Substrate Recognition of Squalene and Oxidosqualene Cyclases : Substrate Conformations are Controlled by Molecular Recognition of the Cyclase Enzymes toward Methyl Groups of the Substrates? [in Japanese]

HOSHINO Tsutomu , SATO Tsutomu , KONDO Tomohiro , SAKAI Yoshiyuki , ISHIBASHI Eiichi

There has been remarkable advances in the studies of oxidosqualene and squalene cyclases in the past ten years. First, complete purifications of the enzymes have been attained from several species suc …

Symposium on the Chemistry of Natural Products, symposium papers 39(0), 145-150, 1997

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11

好熱好酸菌Alicyclobacillus acidocaldarius由来スクアレン-ホペン閉環酵素(SHC)の大腸菌における高発現系の構築 : 有機化学・天然物化学 [in Japanese]

佐藤努 , 金井芳則 , 星野力

Journal of the Agricultural Chemical Society of Japan 70(臨時増刊), 241, 1996-03-05
12

微生物色素ピオラセインの生合成 : 化合物12の構造 : 有機化学・天然物化学 [in Japanese]

水岡敬晶 , 金子喜三好 , 星野力

Journal of the Agricultural Chemical Society of Japan 70(臨時増刊), 241, 1996-03-05
13

ステロールシクラーゼによる化合物(±)1の反応生成物の構造 : 有機化学・天然物化学 [in Japanese]

石橋英一 , 金子喜三好 , 星野力

Journal of the Agricultural Chemical Society of Japan 69(臨時増刊), 232, 1995-07-05
14

10、15-位をエチル基に置換した2、3-オキシドスクアレン(±)1の合成とステロールシクラーゼ反応 : 有機化学・天然物化学 [in Japanese]

石橋英一 , 橋本修司 , 星野力

Journal of the Agricultural Chemical Society of Japan 69(臨時増刊), 232, 1995-07-05
15

微生物色素ビオラセインの生合成遺伝子群のクローニング : 有機化学・天然物化学 [in Japanese]

樋熊学 , 二階堂直樹 , 金井芳則 , 渡辺剛志 , 星野力

Journal of the Agricultural Chemical Society of Japan 69(臨時増刊), 232, 1995-07-05
16

微生物色素ビオラセインの生合成 : Compound 10と11の構造 : 有機化学・天然物化学 [in Japanese]

水岡敬晶 , 小田島太郎 , 星野力

Journal of the Agricultural Chemical Society of Japan 69(臨時増刊), 232, 1995-07-05

星野力 HOSHINO Tsutomu

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星野 力 HOSHINO Tsutomu

Articles: 1-16 of 16

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星野力 HOSHINO Tsutomu

Articles:　 1-16 of 16