CiNii Articles - TANAKA HARUO

1

gp120-CD 4 Binding Inhibitors Having Anti-HIV Activity [in Japanese]

TANAKA Haruo , MATSUZAKI Keiichi , OMURA Satoshi

Nippon Nōgeikagaku Kaishi 71(5), 530-534, 1997-05

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2

84(P77) STRUCTURE OF CHLOROPEPTIN, A PEPTIDE ANTIBIOTIC INHIBITING gp120-CD4 BINDING [in Japanese]

Matsuzaki Keiichi , Smith Amos B. III , Gouda Hiroaki , Okamoto Megumi , Hirono Shuichi , Tanaka Haruo , Omura Satoshi , McCauley John A. , Sprengeler Paul A. , Furst George T.

Chloropeptin, a novel peptide antibiotic isolated from a culture broth of S treptomyces sp. WK-3419, is a potent inhibitor of the binding between gp120 envelope glycoprotein of HIV-1 and the CD4 recep …

Symposium on the Chemistry of Natural Products, symposium papers 38(0), 499-504, 1996

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3

51(P11) STUDIES ON ANDRASTINS, NEW PROTEIN FARNESYLTRANSFERASE INHIBITORS PRODUCED BY PENICILLIUM sp. [in Japanese]

Uchida Ryuji , Shiomi Kazuro , Inokoshi Junji , Tanaka Haruo , Iwai Yuzuru , Takayanagi Hiroaki , Omura Satoshi

During our screening for protein farnesyltransferase (PFTase) inhibitors of microbial origin, we have found new compounds, andrastins A〜D (1〜4), from the cultured broth of Penicillium sp. FO-3929. The …

Symposium on the Chemistry of Natural Products, symposium papers 38(0), 301-306, 1996

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4

1 THE FIRST TOTAL SYNTHESIS OF (+)-PYRIPYROPENE A; POTENT BIOAVAILABLE INHIBITOR OF ACYL-CoA : CHOLETEROL ACYLTRANSFERASE [in Japanese]

SUNAZUKA Toshiki , NAGAMITSU Tohru , TANAKA Haruo , HARIGAYA Yoshihiro , OBATA Rika , TOMODA Hiroshi , OMURA Satoshi

Rccently we disclosed the isolation, biological properties, and structures of the pyripyropenes which apparently represent the most potent naturally ACAT inhibitors reported to date. Importanly, pyrip …

Symposium on the Chemistry of Natural Products, symposium papers 37(0), 1-6, 1995

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5

A Novel Testosterone 5α-Reductase Inhibitor, 8', 9'-Dehydroascochlorin Produced by Verticillium sp. FO-2787

TAKAMATSU S , RHO Mun-Chual , MASUMA Rokuro , HAYASHI Masahiko , KOMIYAMA Kanki , TANAKA Haruo , OMURA Satoshi

A new testosterone 5α-reductase inhibitor, 8'9'-dehydroascochlorin, was isolated from the cultured mycelium of Verticillium sp. FO-2787. This compound (M.W. : 402,C_<23>H_<27>ClO_4) consis …

Chem. Pharm. Bull. 42, 953-956, 1994

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6

受容体作用物質:概論--探索とそれを用いる細胞機能解明の現状と展望 (細胞機能研究のための低分子プロ-ブ) -- (受容体作用物質) [in Japanese]

田中晴雄

Protein,nucleic acid and enzyme 38(11), p1813-1826, 1993-08

Ichushi Web
7

微生物由来の受容体作用物質 [in Japanese]

田中晴雄 , 大村智

Bioscience & industry 51(4), p283-289, 1993-04

Ichushi Web
8

10 TOTAL SYNTHESIS OF (+)-LACTACYSTIN, THE FIRST NON-PROTEIN NEUROTROPHIC FACTOR [in Japanese]

Sunazuka T. , Omura S. , Nagamitsu T. , Matsuzaki K. , Tanaka H. , Smith Amos B. III

Neurotrophic agents such as nerve growth factor (NGF), a well-characterized protein, are required for the survial and function of neurons. In 1991 we reported the isolation and characterization of the …

Symposium on the Chemistry of Natural Products, symposium papers 35(0), 72-79, 1993

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9

29 MOLECULAR GENETICS OF AVERMECTIN BIOSYNTHESIS [in Japanese]

Ikeda H. , Pang C.-H. , Tanaka H. , Omura S.

The anthelmintic antibiotic avermectin complex produced by Streptomyces avermitilis is a family of eight closely related components. Our interests are focused breeding mutants which produce new compon …

Symposium on the Chemistry of Natural Products, symposium papers 34(0), 220-226, 1992

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10

秦藤樹博士・大村智博士日本学士院賞受賞 [in Japanese]

TANAKA HARUO

Farumashia 26(8), 843, 1990

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11

骨芽細胞様細胞(MC3T3-E1)に及ぼすTGF-βの影響(動物-細胞培養-) [in Japanese]

竹嶋秀雄 , 片桐岳信 , 李富雄 , 田中晴雄 , 大村智

Journal of the Agricultural Chemical Society of Japan 62(3), 331, 1988-03-15

Ichushi Web
12

Effects of Phytosterols on Anti-complementary Activity(Pharmacognosy,Chemical)

YAMADA H. , YOSHINO MASAMI , MATSUMOTO TSUKASA , NAGAI TAKAYUKI , KIYOHARA HIROAKI , CYONG JONG-CHOL , NAKAGAWA AKIRA , TANAKA HARUO , OMURA SATOSHI

Several phytosterols, stigmasterol, campesterol and β-sitosterol, were shown to have potent anti-complementary activities. Stigmasterol was the most potent. A marked consumption of C4 was observed to …

Chem. Pharm. Bull. 35, 4851, 1987

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13

日本薬学会学術賞紹介大村智氏の業績 [in Japanese]

TANAKA HARUO

Farumashia 22(5), 501-502, 1986

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14

Quantitative Structure-Activity Relationships of O-Acyl Derivatives of Leucomycin for Antimicrobial and Ribosome-Binding Activities

TANAKA HARUO , MORIGUCHI IKUO , HIRONO SHUICHI , OMURA SATOSHI

Quantitative structure-activity relationships analyses of O-acylleucomycins for antimicrobial and ribosome-binding activities were carried out based on partition coefficient values. The analyses indic …

Chemical & pharmaceutical bulletin 33(7), 2803-2808, 1985-07-25

Ichushi Web
15

75 Structure and Biosynthesis of Setomimycin [in Japanese]

Kakinuma K. , Imamura N. , Ikekawa N. , Tanaka H. , Minami S. , Omura S.

The Structure of an antibacterial and antitumor antibiotic Setomimycin produced by Streptomyces pseudovenezuelae AM-2947, was determined to be a unique substituted 9,9'-bianthryl (1), first to be …

Symposium on the Chemistry of Natural Products, symposium papers 23(0), 576-583, 1980

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16

新しいモノサイクリックβ-ラクタム抗生物質-nocardicin A(トピックス) [in Japanese]

田中晴雄 , 大村智

化学と工業 29(8), p703-704, 1976-08

Ichushi Web
17

2 STRUCTURE OF NEW ANTIBIOTICS, NANAOMYCINS [in Japanese]

Omura S. , Tanaka H. , Koyama Y. , Nagai T. , Marumo H.

In the course of our research for new antibiotics produced by actinomycetes, new antibiotics, nanaomycins A, B, C and D, effective against mycoplasma, fungi and Gram-positive bacteria were obtained fr …

Symposium on the Chemistry of Natural Products, symposium papers 20(0), 9-15, 1976

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田中晴雄 TANAKA HARUO

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田中 晴雄 TANAKA HARUO

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田中晴雄 TANAKA HARUO

Articles:　 1-17 of 17