CiNii Articles - HAYASHI Jun-Ichi

1

Pathogeneses of mitochondrial DNA-based disorders [in Japanese]

石川香 , 林純一 , 中田和人

医学のあゆみ 254(5), 452-458, 2015-08-01

Ichushi Web
2

Specific mtDNA Mutations in Mouse Carcinoma Cells Suppress Their Tumor Formation via Activation of the Host Innate Immune System

Imanishi Hirotake , Takibuchi Gaku , Kobayashi Toshihiko , Ishikawa Kaori , Nakada Kazuto , Mori Masayuki , Kikkawa Yoshiaki , Takenaga Keizo , Toyama-Sorimachi Noriko , Hayashi Jun-Ichi , 中田和人 , 林純一

mammalian species, mitochondrial DNA (mtDNA) with pathogenic mutations that induce mitochondrial respiration defects has been proposed to be involved in tumor phenotypes via induction of enhanced glyc …

PLOS ONE 8(9), UNSP e75981, 2013-09-16

IR
3

Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development

Hashizume Osamu , Shimizu Akinori , Yokota Mutsumi , Sugiyama Atsuko , Nakada Kazuto , Miyoshi Hiroyuki , Itami Makiko , Ohira Miki , Nagase Hiroki , Takenaga Keizo , Hayashi Jun-Ichi , 橋爪脩 , 中田和人 , 林純一

It has been hypothesized that respiration defects caused by accumulation of pathogenic mitochondrial DNA (mtDNA) mutations and the resultant overproduction of reactive oxygen species (ROS) or lactates …

Proceedings of the National Academy of Sciences of the United States of America 109(26), 10528-10533, 2012-06

IR
4

Mitochondrial DNA Mutations Regulate Metastasis of Human Breast Cancer Cells

Imanishi Hirotake , Hattori Keisuke , Wada Reiko , Ishikawa Kaori , Fukuda Sayaka , Takenaga Keizo , Nakada Kazuto , Hayashi Jun-Ichi , 今西泰赳 , 中田和人 , 林純一

Mutations in mitochondrial DNA (mtDNA) might contribute to expression of the tumor phenotypes, such as metastatic potential, as well as to aging phenotypes and to clinical phenotypes of mitochondrial …

PLoS ONE 6(8), e23401, 2011-08

IR
5

Mitochondrial diseases [in Japanese]

中田和人 , 林純一

医学のあゆみ 238(5), 498-504, 2011-07-30

Ichushi Web
6

Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system

Nishiyama Satoshi , Shitara Hiroshi , Nakada Kazuto , Ono Tomio , Sato Akitsugu , Suzuki Hidenori , Ogawa Tetsuhiro , Masaki Haruhiko , Hayashi Jun-Ichi , Yonekawa Hiromichi , 西山哲史 , 中田和人 , 林純一

The phenotypes of mitochondrial diseases caused by mutations in mitochondrial DNA (mtDNA) have been proposed to be strictly regulated by the proportion of wild-type and pathogenically mutated mtDNAs. …

Biochemical and biophysical research communications 401(1), 26-31, 2010-10-08

IR
7

The innate immune system in host mice targets cells with allogenic mitochondrial DNA

Ishikawa Kaori , Toyama-Sorimachi Noriko , Nakada Kazuto , Morimoto Mami , Imanishi Hirotake , Yoshizaki Mariko , Sasawatari Shigemi , Niikura Mamoru , Takenaga Keizo , Yonekawa Hiromichi , Hayashi Jun-Ichi , 中田和人 , 林純一

Mitochondrial DNA (mtDNA) has been proposed to be involved in respiratory function, and mtDNA mutations have been associated with aging, tumors, and various disorders, but the effects of mtDNA importe …

Journal of experimental medicine 207(11), 2297-2305, 2010-10

IR
8

Pathogenesis by failures of mitochondrial central dogma [in Japanese]

中田和人 , 石川香 , 林純一

Cell technology 29(5), 466-473, 2010
9

Mitochondria theory of tumor metastasis: ROS-generating mtDNA mutations reversibly regulate tumor cell metastasis [in Japanese]

石川香 , 林純一

Protein, nucleic acid and enzyme 54(1), 40-48, 2009-01

Ichushi Web
10

A model mouse for mitochondrial DNA-based diseases [in Japanese]

NAKADA Kazuto , SATO Akitsugu , HAYASHI Jun-Ichi

Patient studies suggested that accumulation of pathogenic mitochondrial (mt) DNAs having large-scale deletion or point mutation and the resultant mitochondrial respiratory abnormalities are associated …

Rinsho Shinkeigaku 48(11), 1013-1015, 2008-11-01

J-STAGE Ichushi Web References (10)
11

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis

Ishikawa Kaori , Hashizume Osamu , Koshikawa Nobuko , Fukuda Sayaka , Nakada Kazuto , Takenaga Keizo , Hayashi Jun-Ichi , 中田和人 , 林純一

We addressed the issue of whether enhanced glycolysis caused by mtDNA mutations independently induces metastasis in tumor cells using mtDNA transfer technology. The resultant trans-mitochondrial cybri …

FEBS letters 582(23), 3525-3530, 2008-10

IR
12

Generation of model mice expressing mitochondrial-genome diseases [in Japanese]

HAYASHI Jun-Ichi

DNA多型 = DNA polymorphism 16, 1-6, 2008-05-30

Ichushi Web References (13)
13

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

ISHIKAWA K , Takenaga Keizo , Akimoto Miho , Koshikawa Nobuko , Yamaguchi Aya , Imanishi Hirotake , Nakada Kazuto , Honma Yoshio , Hayashi Jun-Ichi , 中田和人 , 林純一

Mutations in mitochondrial DNA (mtDNA) occur at high frequency in human tumors, but whether these mutations alter tumor cell behavior has been unclear. We used cytoplasmic hybrid (cybrid) technology t …

Science 320(5876), 661-664, 2008-05

IR Cited by (8)
14

フリーラジカルとエイジング--ミトコンドリア間相互作用から老化ミトコンドリア原因説を再考する (特集エイジングの科学) [in Japanese]

中田和人 , 林純一

Journal of health,physical education and recreation 58(4), 242-246, 2008-04

Ichushi Web
15

Special Review 哺乳類ミトコンドリアDNAにおける組換え [in Japanese]

佐藤晃嗣 , 中田和人 , 林純一

Cell technology. 25(1), 54-59, 2006-01

Ichushi Web
16

生きているGFPミトコンドリアの長期観察 (二層膜オルガネラの遺伝学) -- (オルガネラテクノロジー動物ミトコンドリアのテクノロジー) [in Japanese]

設楽浩志 , 林純一 , 米川博通

Protein, nucleic acid and enzyme 50(14), 1909-1911,1712, 2005-11
17

ミトコンドリア移植による病原性ミトコンドリアDNAの診断 (二層膜オルガネラの遺伝学) -- (オルガネラテクノロジー動物ミトコンドリアのテクノロジー) [in Japanese]

石川香 , 林純一

Protein, nucleic acid and enzyme 50(14), 1904-1906, 2005-11

Ichushi Web
18

ミトコンドリアゲノムの相補作用 (二層膜オルガネラの遺伝学) -- (オルガネラダイナミクス動物オルガネラダイナミクス) [in Japanese]

佐藤晃嗣 , 林純一

Protein, nucleic acid and enzyme 50(14), 1863-1867,1712, 2005-11

Ichushi Web
19

ミトコンドリア遺伝子病モデルマウス (二層膜オルガネラの遺伝学) -- (哺乳類のミトコンドリア哺乳類ミトコンドリアゲノムの変異と疾患) [in Japanese]

中田和人 , 林純一

Protein, nucleic acid and enzyme 50(14), 1774-1777, 2005-11

Ichushi Web
20

ミトコンドリアDNAの母性遺伝と組換え (二層膜オルガネラの遺伝学) -- (哺乳類のミトコンドリア哺乳類ミトコンドリアゲノムの遺伝と進化) [in Japanese]

佐藤晃嗣 , 設楽浩志 , 林純一 [他]

Protein, nucleic acid and enzyme 50(14), 1744-1748, 2005-11

Ichushi Web

林純一 HAYASHI Jun-Ichi

Articles:　 1-20 of 40

Search this author

Related Authors

Related Journals

林 純一 HAYASHI Jun-Ichi

Articles: 1-20 of 40

Search this author

Related Authors

Related Journals

林純一 HAYASHI Jun-Ichi

Articles:　 1-20 of 40