中崎 敦夫 Nakazaki Atsuo

ID:9000006709949

東理大薬 Faculty of Pharmaceutical Sciences, Tokyo University of Science (2010年 CiNii収録論文より)

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Articles:  1-8 of 8

  • Total Synthesis of (+)-TMC-151C Using Vinylogous Mukaiyama Aldol Reaction and Ring Closing Metathesis  [in Japanese]

    Matsui Ryosuke , Seto Kentaro , Sato Yuna , Fujita Kazuhiro , Suzuki Takahiro , Nakazaki Atsuo , Kobayashi Susumu

    We have previously developed a highly stereoselective vinylogous Mukaiyama aldol reaction (VMAR) usin gvinylketene silyl N,O-acetal 1, which provides a unique and remarkable entry to a remote asymmetr …

    Symposium on the Chemistry of Natural Products, symposium papers 52(0), 13-18, 2010

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  • Total Synthesis of Fomitellic Acid B  [in Japanese]

    Yamaoka Makoto , Fukatsu Yuichi , Kanatsu Kazuki , Nakazaki Atsuo , Kobayashi Susumu

    Fomitellic acids, isolated from the mycelium of a basidiomycete, Fomitella fraxinea, are specific inhibitors of DNA polymerase α and β. It was also reported that inhibition of DNA polymerase activity …

    Symposium on the Chemistry of Natural Products, symposium papers 51(0), 199-204, 2009

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  • Stereoselective Synthesis of Highly Functionalized Spirocyclic Compounds based on Claisen Rearrangement and its Application to the Synthesis of Natural Products  [in Japanese]

    NAKAZAKI Atsuo , KOBAYASHI Susumu

    Spirocyclic scaffolds are embedded in many biologically active natural compounds, including candidates for medicines, perfumes and agricultural chemicals. Therefore, a development of efficient synthet …

    Journal of Synthetic Organic Chemistry, Japan 66(2), 124-138, 2008-02-01

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  • 38 Total Synthesis of Norzoanthamine(Oral Presentation)  [in Japanese]

    Yamashita Daisuke , Murata Yoshihisa , Nakazaki Atsuo , Kobayashi Susumu

    Norzoanthamine (1), isolated from zoanthid Zoanthus sp. by Uemura and co-workers in 1995, exhibits inhibition of IL-6 production. Further its hydrochloride was found to suppress the loss of bone weigh …

    Symposium on the Chemistry of Natural Products, symposium papers 50(0), 251-256, 2008

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  • 26 Synthesis of Highly Functionalized Spirocyclic Compounds based on Claisen Rearrangement and its Application to the Synthesis of Natural Products  [in Japanese]

    Nakazaki Atsuo , Miyamoto Hiroshi , Era Tomohiro , Okawa Yoichiro , Hirano Tomohiro , Kobayashi Susumu

    Spirocyclic scaffolds are embedded in many biologically active natural compounds, including candidates for medicines, perfumes and agricultural chemicals. Therefore, a development of efficient synthet …

    Symposium on the Chemistry of Natural Products, symposium papers 49(0), 151-156, 2007

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  • P-45 Synthesic Study on Telomerase Inhibitor, D8646-2-6  [in Japanese]

    Kanai Akira , Nakazaki Atsuo , Kobayashi Susumu , Kuramochi Kouji

    D8646-2-6 (1) was isolated as an inhibitor of telomerase from the culture broth of Epicoccum purpurascens. It has a unique C^3-pyranosyl 4-hydroxypyrone structure with a conjugated heptaene side chain …

    Symposium on the Chemistry of Natural Products, symposium papers 48(0), 373-378, 2006

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  • P-39 Synthesis and Structure Determination of Pseudodeflectusin  [in Japanese]

    Saito Fumiyo , Ogawa Akitsu , Kamisuki Shinji , Takeda Yoshifumi , Nakazaki Atsuo , Mizushina Yoshiyuki , Sugawara Fumio , Kobayashi Susumu

    In the course of our program for the constructon of small molecule library from natural resources, we isolated pseudodeflectusin (1), a new isochroman derivative, from a culture broth of Aspergillus p …

    Symposium on the Chemistry of Natural Products, symposium papers 47(0), 349-354, 2005

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  • P-37 Synthetic Study on Antitumor Antibiotic, PD113271  [in Japanese]

    Takeuchi Toshifumi , Kuramochi Kouji , Sugawara Fumio , Nakazaki Atsuo , Kobayashi Susumu

    Fostriecin(1), along with two structurally related compounds PD113270(2), PD113271(3), are structurally unique and naturally-occurring phoshate monoesteres that exhibit potent and efficacious antitumo …

    Symposium on the Chemistry of Natural Products, symposium papers 47(0), 343-348, 2005

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