田村 正和 TAMURA MASAKAZU

ID:9000256162125

徳島大学医学部第三内科 The Third Department of Internal medicine, School of Medicine, Tokushima University (1988年 CiNii収録論文より)

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Articles:  1-19 of 19

  • CLINICAL STUDY ON CS-807

    OZAKI TOSHIO , TAMURA MASAKAZU , YASUOKA SUSUMU , OGURA TAKASHI

    CS-807を呼吸器感染症5例 (急性気管支炎2例, 気管支肺炎1例,慢性気管支炎急性増悪例2例) に使用し, その臨床効果, 細菌学的効果および副作用, 臨床検査値に及ほす影響について検討した。<BR>いずれの症例においても, 咳漱, 喀痰, 発熱の臨床症状は投与後3~7日目に消失した。白血球数増多, 赤沈充進, CRP陽性といった検査所見もCS-807投与により改善し, 臨床的に有 …

    CHEMOTHERAPY 36(Supplement1), 535-537, 1988

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  • CLINICAL STUDIES ON L-105

    TAMURA MASAKAZU , NAKAGAWA MASARU , TSUBURA EIRO , TAKISHITA YOSHIHIRO

    L-105を10例の呼吸器感染症に使用した。その内訳は, 肺炎7例, 慢性気管支炎2例, 急性気管支炎1例であり, そのうち6例が基礎疾患を有していた。投与方法は, 1回1~29を1日2回, one shot静注または点滴静注とした。臨床効果判定は, 除外2例を除く8例について行い, 有効4例, やや有効1例, 無効3例であった。副作用は, 1例に下痢, 4例に発疹を認めたが, いずれも軽度であっ …

    CHEMOTHERAPY 34(Supplement3), 328-331, 1986

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  • Comparative Study of TMS-19-Q and Midecamycin for Respiratory Tract Infection by Double-Blind Method

    KOBAYASHI Hiroyuki , YAMAMOTO Asako , UZUKA Yoshio , ANDO Masayuki , SUGIMOTO Mineharu , SUGA Moritaka , ARAKI Shukuro , FUKUDA Yasutsugu , TOKUNAGA Katsumasa , TOKUOMI Haruhiko , ITOGA Takashi , NASU Masaru , TAKEBE Kazuo , GOTO Jun , GOTO Yoichiro , TASHIRO Takayoshi , KOBARI Kazumine , IRABU Yuei , KINJO Yutoku , NAKATOMI Masao , TANAKA Tsuneo , KOSAKA Shiro , NAKAMURA Teruo , YOSHIDA Shuichiro , TAMURA Masao , ITO Takashi , CHIBA Taro , OGATA Ryoji , TANIFUJI Kazuo , NIHEI Tomoko , ITAKURA Kotaro , KONNO Kiyoshi , OIZUMI Kotaro , NAGAI Kosaku , HAYASHI Izumi , ABE Tatsuya , KATSU Masataka , OKUI Shinji , ADACHI Masanori , SAITO Atsushi , TAKEDA Hiroaki , SHIBA Kohya , MIYAHARA Tadashi , UGAI Tetsuro , YAMANE Yoshiji , MASHIMO Keimei , NAKAGAWA Keiichi , KOYAMA Masaru , AKIYOSHI Ryuji , MURATA Ichiro , FUJIMORI Ippei , KOHNO Kohta , KOBAYASHI Yoshio , OBANA Mitsuo , MATSUMOTO Fumio , ODAGIRI Shigeki , IKEDA Hirotada , SUZUKI Kaneo , MUROHASHI Kou , KANEKO Tamotsu , SEKINE Osamu , USUDA Yoshimaru , SAITO Akira , AOKI Nobuki , YAMASAKU Fusanosuke , OYAMA Kaoru , YAMAMOTO Toshiyuki , KATO Masahito , NANJO Kunio , YAMAMOTO Motoko , HANAKI Hidekazu , NAGASAKA Hirohiko , ITO Tsuyoshi , TOMIZAWA Masumi , TAKEUCHI Toshihiko , KOHNO Masakazu , MIKI Fumio , TAKAMATSU Kenji , OKAMOTO Yuruko , MAEHARA Keigo , IIDA Yube , SOEJIMA Rinzo , MATSUSHIMA Toshiharu , NIKI Yoshihito , NAKAYAMA Ichiro , KAWANE Hiroshi , KAWANISHI Masayoshi , NAKAHAMA Chikara , WATANABE Masatoshi , HINO Jiro , YAMAKIDO Michio , ODA Yuzo , KURIMURA Osamu , SASAKI Hideo , FUKUHARA Hirofumi , HIRAGA Yomei , TAMURA Masakazu , GOTO Toshihiro , TSUBURA Eiro , SAWAE Yoshiro , OKADA Kaoru , KUMAGAI Yukio , HARA Kohei , SAITO Atsushi , IZUMIKAWA Kinichi , YAMAGUCHI Keizo , KIKUCHI Kohki , SUZUYAMA Yoji , SHIGENO Yoshiteru , KOMORI Munetaka , ITO Naomi , SAI Masao , IWASAKI Hiromaru , WATANABE Koichi , IKEBE Akira , YAMADA Kozo , MATSUMOTO Keizo

    新マクロライド系抗生物質TMS-19-Q (TMS) の肺炎を中心とした呼吸器感染症に対する有効性, 安全性および有用性を検討するため, Midecamycin (MDM) を対照として二重盲検比較試験を実施した.投与量は基礎検討, 一般臨床試験等の結果より, TMS1日600mg分3, MDM1日1,200mg分3とし, 以下の結果を得た.<BR>1.全肺炎における臨床効果はTMS群 …

    Kansenshogaku Zasshi 59(2), 201-226, 1985

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  • A Double-Blind Comparative Study of Aspoxicillin and Piperacillin in the Treatment of Respiratory Tract Infections

    SAITO Akira , TAKEUCHI Keisuke , FUJIMORI Ippei , KOBAYASHI Yoshio , NAKAMURA Yasushi , FUKAYA Kazufuto , TAKAGI Kenzo , YAMAKAWA Ikuo , HARA Michihiro , SATAKE Tatsuo , TAKEUCHI Toshihiko , KATO Masahito , KOJIMA Aiji , KITAURA Saburo , HANAKI Hidekazu , YAMAMOTO Toshiyuki , SUZUKI Kanzo , KISHIMOTO Akihiko , ABE Youichi , TORIGAI Katsutaka , OHYAMA Kaoru , SUZUKI Kuninori , OHYA Nobuo , SHIMOYAMA Kazuo , HAYASE Mitsuru , MAEKAWA Nobuo , NAKANISHI Michiyasu , AOKI Kohei , MATSUBARA Tsuneo , IKEDA Nobuaki , IWATA Takekuni , INABA Nobuo , TSUJINO Hiroyuki , OKAMOTO Yuruko , TAKASHIRO Yoshinobu , MAEHARA Keigo , YOSHIOKA Muneto , IIDA Yube , OKUBO Hiroshi , UEDA Yoshihiro , MIKI Fumio , TAKAMATSU Kenji , MIYAMOTO Osamu , TSUBURA Eiro , GOTO Toshihiro , OHNISHI Shinji , TAMURA Masakazu , SOEJIMA Rinzo , NIKI Yoshito , WATANABE Masatoshi , YAMAKIDO Michio , HAYASHI Kanoko , SAWAE Yoshiro , KUSABA Tomohiro , KASHIWAGI Seizaburo , UEDA Akira , SHINOHARA Masahide , OKADA Kaoru , ONO Michio , TAKII Masahide , OTONARI Takatoshi , HARA Kohei , SAITO Atsushi , YAMAGUCHI Keizo , SUZUYAMA Yoji , SHIGENO Yoshiteru , WATANABE Koichi , UJIIE Akira , NAGASAWA Masao , MATSUMOTO Keizo , SHISHIDO Harumi , TAKAHASHI Atsushi , TAKASUGI Masakazu , TAMAKI Shigeru , KIMURA Hisao , ANDO Masayuki , SUGIMOTO Mineharu , SUGA Moritaka , YAJIMA Osamu , TOKUNAGA Katsumasa , FUKUDA Yasutsugu , TOKUOMI Haruhiko , NAGAHAMA Fumio , NISHIHARA Hisaji , ISHIKAWA Kiyofumi , SASAKI Yuichi , NAKABAYASHI Takehito , KOROKU Tetsuji , KURODA Rensuke , SHIMOMURA Jutaro , OSHIMA Shin-ichi , ONODERA Sokichi , SASAKI Nobuhiro , SUZUKI Akira , NATSUIZAKA Tohru , NAKAYAMA Ichiro , HIRAGA Yohmei , KIKUCHI Kohki , YAMAMOTO Asako , KIKUIRI Tsuyoshi , MURAKAMI Tadashi , TSUCHIHASHI Kazufumi , TAKEBE Kazuo , OKAMOTO Katsuhiro , TOSHIDA Shuichiro , OHMI Tadanao , TOMIZAWA Masumi , TAKAHASHI Shuichi , KARIYA Katsutoshi , ONUMA Tomio , OCHIAI Shigeru , KUMASAKA Yoshihiro , YANAGIYA Shigetoshi , UEHARA Osamu , WATABIKI Yasukimi , MASAKI Naoyoshi , TAMURA Toyoichi , ABE Morikuni , TAMAZAWA Naoki , INOOKA Hajime , TAMURA Masao , ITOH Takashi , TAKEUCHI Ken-ichi , OGATA Ryoji , KOMURO Jun , ITOH Hiroaki , TAKISHIMA Tamotsu , TANNO Yasuo , SHIBAKI Hidetoshi , KONNO Kiyoshi , OHIZUMI Kotaro , WATANABE Akira , KASHIWAGI Makoto , TOGASHI Hideo , SATO Hidetaka , HAYASHI Masato , ITOH Tsugushi , HAYASHI Izumi , SEKINE Osamu , CHIMOTO Takehisa , USUDA Yoshimaru , AOKI Nobuki , YAMASAKU Fusanosuke , SUZUKI Yasutoshi , KATSU Masataka , ADACHI Masanori , MASHIMO Keimei , UKAI Tetsuro , ITOH Chizuru , SAITO Atsushi , TANAKA Masahiro , MIYAHARA Tadashi , TANIMOTO Hiroichi , TACHIBANA Akio , NAKAMORI Yoshitaka , CHONABAYASHI Naohiko , YOSHIMURA Kunihiko , KABE Junzaburo , ISHIBASHI Hiroyoshi , IKEMOTO Hideo , WATANABE Kazuyoshi , ITO Choei , NAKAGAWA Keiichi , KOYAMA Masaru , KIN Kohjin , UEDA Masami , IIJIMA Fukuo , AKIYOSHI Ryuji , FUNATSU Yuzo , HIGASHI Fuyuhiko , KOBAYASHI Hiroyuki , OSHITANI Hiroshi

    Aspoxicillin (ASPC, 治験番号TA-058) の呼吸器感染症に対する有効性と安全性ならびに有用性をPiperacillin (PIPC) を対照薬とする二重盲検法により比較検討した.投与量は両薬剤とも4g/日 (2g×2回/日) とし, 原則として14日間点滴静注を行い, 以下の成績を得た.<BR>1) 呼吸器感染症に対するASPCとPIPCとの臨床効果は, 全症例で …

    Kansenshogaku Zasshi 59(2), 164-200, 1985

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  • A Comparative Study Between Cefminox (MT-141) and Cefotaxime in Respiratory Tract Infections

    MIKI Fumio , ABE Morikuni , IIDA Yube , SOEJIMA Rinzo , NIKI Yoshito , NAKAHAMA Chikara , ADACHI Michifumi , KURIMURA Osamu , NOMA Koji , TSUBURA Eiro , TAMURA Masakazu , SAWAE Yoshiro , TAKASHIRO Yoshinobu , OKADA Kaoru , KUMAGAI Yukio , MATSUBA Kenichi , NAWATA Takahiro , KAJI Masaro , ICHIKAWA Yoichiro , TANAKA Nisaburo , HAYASHI Toshiharu , MITSUTAKE Yoshiyuki , FUJINO Kazuma , NAKAYAMA Ichiro , HARA Kohei , SAITO Atushi , YAMAGUCHI Keizo , SUZUYAMA Yoji , SHIGENO Yoshiteru , NAKAMURA Isao , KOMORI Munetaka , SHINZATO Ken , OGATA Hirofumi , ITO Naomi , TOMIZAWA Masumi , MATSUMOTO Keizo , NAGATAKE Tsuyoshi , RIKITOMI Naoto , ANDO Masayuki , SUGIMOTO Mineharu , SUGA Moritaka , ITOGA Takashi , NASU Masaru , GOTO Yoichiro , GOTO Jun , NAGAHAMA Fumio , TASHIRO Takayoshi , NAKABAYASHI Takehito , KOROKU Tetsuji , HIRAGA Yomei , SUZUKI Katsuo , KON Hiroshi , INOUE Eiji , YOKOTA Yasumasa , OHASHI Ryoji , SHIMOMURA Jutaro , GOCHO Yoichi , NISHIHARA Hisashi , TAKEBE Kazuo , MASUDA Mitsuo , MURAKAMI Seiichi , KUMASAKA Yoshihiro , NAKAMURA Mitsuo , TERAGAKI Masakazu , IRIE Tatsuro , YONEDA Masashi , TAKISHIMA Tamotsu , TANNO Yasuo , KONNO Kiyoshi , OIZUMI Kotaru , AONUMA Seiichi , HAYASHI Izumi , ABE Tatsuya , KATSU Masataka , AKIOKA Kaname , TAKIZUKA Hisashi , SAITO Reiko , MASHIMO Keimei , UKAI Tetsuro , TANIMOTO Hiroichi , NAKATANI Ryuoh , YOSHIMURA Kunihiko , NAKAMORI Yoshitaka , CHONABAYASHI Naohiko , NAKATA Koichiro , YOSHIYAMA Minoru , KABE Junzaburo , ISHIBASHI Hiroyoshi , SANO Yasuyuki , IKEMOTO Hideo , WATANABE Kazuyoshi , SAITO Atsushi , NAKAGAWA Keiichi , WATANABE Kentaro , KOYAMA Masaru , KOBAYASHI Hiroyuki , HIRAGA Toru , KONO Kota , TAKAMURA Kenji , OSHITANI Hiroshi , FUKUSHIMA Kokichi , ITO Akira , ODAGIRI Shigeki , IKEDA Hirotada , SUZUKI Kaneo , MUROHASHI Kou , KANEKO Tamotsu , MURATA Tetsuto , NOSE Keinosuke , FUKAYA Kazufuto , TAKIGAMI Tadashi , FUJIMORI Ippei , KOBAYASHI Yoshio , OBANA Mitsuo , TAKEDA Hajimu , YAMASAKU Fusanosuke , SUZUKI Yasutoshi , SEKINE Osamu , SAITO Akira , USUDA Yoshimaru , AOKI Nobuki , OYAMA Kaoru , TAKEUCHI Toshihiko , KATO Masahito , HANAKI Hidekazu , YAMAMOTO Toshiyuki , SUZUKI Kanzo , KISHIMOTO Akihiko , TORIKAI Katsutaka , UJIIE Akira , ASHIHARA Mutsumi , SUGIHARA Tatsuo , MAEKAWA Nobuo , NAKANISHI Michiyasu , MATSUBARA Tsuneo , IKEDA Nobuaki , SHIBATA Ataka , TAKAMATSU Kenji , OKAMOTO Yuruko , MAEHARA Keigo

    新しいセファマイシン系抗生物質Cefminox (MT-141以下CMNXと略す) の呼吸器感染症に対する有効性と安全性を, Cefotaxime (以下CTXと略す) を対照薬剤として, well-controlled studyにより比較検討した.<BR>感染症状明確な15歳以上の, 慢性呼吸器感染症 (慢性気管支炎, び漫性汎細気管支炎, 感染を伴った気管支拡張症・肺気腫・肺線維 …

    Kansenshogaku Zasshi 59(2), 115-163, 1985

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  • A comparative Study Between Aztreonam and Cefoperazone in Respiratory Tract Infections

    SAITO Atsushi , SAITO Akira , KOBAYASHI Yoshio , OBANA Mitsuo , YAMAMOTO Toshiyuki , SUZUKI Kanzo , KISHIMOTO Akihiko , TAKAGI Kenzo , YAMAKI Ken-ichi , YOKOYAMA Shigeki , TANO Masao , IWATA Hitoshi , NAKAYAMA Ichiro , SASAMOTO Motohide , SATAKE Tatsuo , MAEKAWA Nobuo , KUZE Fumiyuki , NAKANISHI Michiyasu , NISHIYAMA Hideki , TSUJINO Hiroyuki , INABA Nobuo , ODA Yoshiro , KAGIOKA Akira , TOMIZAWA Masumi , IWATA Takekuni , OIDA Kazukiyo , NAKAI Hitoshi , SAKAMOTO Hiroko , KATAGAMI Nobuyuki , MATSUYAMA Eiichi , USHIDA Shin-ichi , IKEDA Sadao , AOKI Kohei , SHIOTA Kenzo , ISHIKAWA Kiyofumi , YAMADA Yoshio , KOBAYASHI Keiji , YASUNAGA Kojiro , OKAMOTO Yuruko , MAEHARA Keigo , IIDA Yube , UEDA Yoshihiro , OOKUBO Akira , MIKI Fumio , IKUNO Yoshiyasu , SUZUKI Akira , INOUE Eiji , YOSHIYAMA Minoru , MURATA Tetsuro , TANIZAWA Shin-ichi , SAKAMOTO Kazuo , SAKAI Hirozumi , TAKAMATSU Kenji , HIGASHINO Kazuya , HADA Toshikazu , NABESHIMA Kenji , NAKAMURA Mitsunari , HIROSAKI Akitaka , NAKANO Takashi , SOEJIMA Rinzo , NIKI Yoshihito , NISHIMOTO Yukio , YAMAKIDO Michio , KAMITSUNA Akimitsu , HASEGAWA Kenji , KURIMURA Osamu , ARATANI Yoshihiko , NATORI Hiroshi , TSUBURA Eiro , TAMURA Masakazu , SAWAE Yoshiro , OKADA Kaoru , SHIGEMATSU Nobuaki , MATSUMOTO Norichika , KISHIKAWA Reiko , YOKOTA Takeo , NAGANO Hitoshi , HARA Kohei , HIRAGA Yohmei , SAITO Atsushi , YAMAGUCHI Keizo , SUZUYAMA Yoji , SHIGENO Yoshiteru , OKUNO Kazuhiro , WATANABE Koichi , KOTEDA Tsunetoshi , MORI Kenji , MATSUMOTO Keizo , UZUKA Yoshio , KIKUCHI Kohki , RIKITOMI Naoto , NASU Masaru , GOTO Yoichiro , GOTO Jun , TASHIRO Takayoshi , ITOGA Takashi , ANDO Masayuki , SUGIMOTO Mineharu , SUGA Moritake , MIYAZAKI Akira , YAMAMOTO Asako , ARAKI Shukuro , KOBARI Kazumine , NAKATOMI Masao , IRABU Yuei , OHGIMI Tatsuo , KINJO Yutoku , SHIBA Kohya , ONODERA Sokichi , SASAKI Nobuhiro , NAGAHAMA Fumio , KURODA Rensuke , IKEDA Yuji , TAKEBE Kazuo , KOSAKA Shiro , KIMURA Ken-ichi , KITAOKA Masafumi , YOSHIDA Shuichiro , MIYAHARA Tadashi , OKAMOTO Katsuhiro , NAKAMURA Teruo , UEHARA Osamu , YANAGIYA Shigetoshi , TAMURA Toyokazu , YASHIRO Hitoshi , KAWAGISHI Takahiko , TAMURA Masao , ITO Takashi , MURAKAMI Takehisa , UEDA Yasushi , ITAKURA Kohtaroh , KURAMITSU Hiroshi , MORIYA Katsura , GOMI Kazutoshi , TAKISHIMA Tamotsu , IDA Shiro , KONNO Kiyoshi , OIZUMI Kotaro , AONUMA Seiichi , SASAKI Reiko , TERAI Tsugio , HAYASHI Izumi , WADA Koichi , TAKEDA Hajimu , ARAKAWA Masaaki , SEKINE Osamu , USUDA Yoshimaru , AOKI Nobuki , YAMASAKU Fusanosuke , SUZUKI Yasutoshi , OHYAMA Kaoru , ABE Shosaku , SUZUKI Kuninori , TAKIZUKA Hisashi , NAKANO Masato , YAMAGATA Hajime , MURAYAMA Yumiko , TSURUMACHI Kazumichi , TANIMOTO Hiroichi , NAKATANI Tatsuo , YOSHIMURA Kunihiko , NAKAMORI Yoshitaka , YAMAGUCHI Etsuro , CHONABAYASHI Naohiko , NAKATA Koichiro , UENO Katsunori , UKAI Tetsuro , HANAOKA Kazuaki , MASHIMO Keimei , NAKAGAWA Keiichi , KOYAMA Masaru , IIJIMA Fukuo , WATANABE Kentaro , OKAZAKI Nozomu , KABE Junzaburo , ISHIBASHI Hiroyoshi , IKEMOTO Hideo , WATANABE Kazuyoshi , SHIMADA Kaoru , INAMATSU Takashi , URAYAMA Kyoko , KOBAYASHI Hiroyuki , TAKAMURA Kenji , SHIMIZU Kihachiro , KAWAKAMI Yoshikazu , MATSUMOTO Fumio , FUKAYA Kazufuto , ODAGIRI Shigeki , MATSUMURA Masanori , SUZUKI Kaneo , MUROHASHI Kou , NOZE Keinosuke , WATANABE Shin-ichiro , SUZUKI Hisako , FUJIMORI Ippei

    グラム陰性菌が起炎菌と推定される呼吸器感染症に対する新しいモノバクタム系抗生剤Aztreonam (AZT) の有効性と安全性を客観的に評価する目的で, Cefoperazone (CPZ) を対照薬として, well controlled comparative studyにより比較検討を行った.<BR>投与法は, 両薬剤とも1回1g (力価) を1日2回, 原則として14日間点滴静 …

    Kansenshogaku Zasshi 59(11), 1084-1120, 1985

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  • CLINICAL STUDIES ON BAY o 9867 (CIPROFLOXACIN)

    TAMURA MASAKAZU , GOTO TOSHIHIRO , TSUBURA EIRO

    BAY o 9867を呼吸器感染症13例 (急性気管支炎4例, 肺炎3例, 気管支拡張症2例, マイコプラズマ肺炎2例, 慢性気管支炎1例, 急性化膿性扁桃腺炎1例) に使用した。<BR>投与は, 1回200mg 1日3回, 又は1回400mg1日2回とし, 総投与量は2.8-17.4gであった。<BR>基礎疾患の増悪がみとめられた3例を除く10例について効果判定をおこなっ …

    CHEMOTHERAPY 33(Supplement7), 486-489, 1985

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  • CLINICAL STUDIES OF IMIPENEM/CILASTATIN SODIUM

    TAMURA MASAKAZU , NAKAGAWA MASARU , TSUBURA EIRO , TAKISHITA YOSHIHIRO

    新しく開発されたカルバペネム系抗生剤imipenem (MK-0787) とrenal dipeptidase阻害剤であるcilastatin sodium (MK-0791) の配合剤MK-0787/MK-0791を12例の呼吸器感染症, 1例の慢性腎孟腎炎の患者に使用し, その有効性ならびに安全性について検討した。<BR>1) 効果判定は13例中12例について行い, 著効6例, 有 …

    CHEMOTHERAPY 33(Supplement4), 667-671, 1985

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  • CLINICAL EVALUATION OF KW-1100 IN URINARY TRACT INFECTIONS

    TAMURA MASAKAZU , NAKAGAWA MASARU , TSUBURA EIRO

    新しく開発されたペニシリン系抗生剤KW-1100の尿路感染症に対する有用性について検討した。<BR>外来, 入院を含む14例 (急性膀胱炎9例, 慢性膀胱炎3例, 慢性腎盂腎炎1例, 尿管・回腸・皮膚吻合術術後尿路感染症1例) に本剤を1回40~80mg, 1日3~4回, 4~21日間, 経口投与した。3例を除く11例について臨床効果判定を行い, 著効2例, 有効5例, やや有効1例, …

    CHEMOTHERAPY 33(Supplement3), 116-120, 1985

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  • CLINICAL STUDIES ON AZTHREONAM

    TAMURA MASAKAZU , NAKAGAWA MASARU , TSUBURA EIRO

    新しく開発されたmonobactam系抗生剤Azthreonamを感染症患者8例に投与し, その臨床効果, 副作用について検討した。<BR>対象患者は, 呼吸器感染症6例, 胆のう炎1例, 多発性肝膿瘍1例であった。<BR>投与方法は, 1回1~29, 1日2~3回, one shot静注, もしくは点滴静注とした。<BR>臨床効果は, 著効, 有効, やや有効 …

    CHEMOTHERAPY 33(Supplement1), 478-480, 1985

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  • Comparative Clinical Study of Ceftazidime and Cefotiam for Respiratory Tract Infections by a Double-blind Method

    HARA Kohei , SAITO Akira , HASEGAWA Hideyuki , KURIHARA Makio , ODAGIRI Shigeki , IKEDA Hirotada , MUROHASHI Kohu , SUZUKI Kaneo , KANEKO Tamotsu , FUKAYA Kazufuto , MATSUMOTO Fumio , YAMAMOTO Toshiyuki , TOMIZAWA Masumi , SUZUKI Kanzo , KISHIMOTO Akihiko , TAKEDA Hajimu , YAMASAKU Fusanosuke , SUZUKI Yasutoshi , SEKINE Osamu , USUDA Yoshimaru , AOKI Nobuki , YUASA Yasuko , NITTA Isao , NAKAYAMA Ichiro , WATANABE Kyoko , OYAMA Kaoru , SHIMIZU Ryusaku , SUZUKI Kuninori , MIKI Fumio , OKAMOTO Yuruko , MAEHARA Keigo , IIDA Yube , YOSHIOKA Muneto , YASUNAGA Kojiro , YASUDA Shinya , UEDA Yoshihiro , OKUBO Hiroshi , SOEJIMA Rinzo , NIKI Yoshihito , KURIHARA Osamu , SASAKI Hideo , MIKITANI Masao , ARATANI Yoshihiko , KANETO Eiji , TSUBURA Eiro , NAKABAYASHI Takehito , GOTO Toshihiro , TAMURA Masakazu , SAWAE Yoshiro , OKADA Kaoru , KUMAGAI Yukio , HIROSE Nobuyuki , SHIGEMATSU Nobuaki , NAGANO Hitoshi , KIHARA Hiromi , KAJI Masaro , KOROKU Tetsuji , ICHIKAWA Yoichiro , TANAKA Fumio , HAYASHI Syunji , MITSUTAKE Yoshiyuki , FUJINO Kazuma , MATSUMOTO Keizo , HARADA Tomoyuki , ISHIZAKI Takeshi , MATSUMOTO Taketsune , KOTEDA Tsunetoshi , SAITO Takahisa , KOHNO Shigeru , NASU Masaru , GOTO Jun , ITOGA Takashi , YAMAZAKI Tsutomu , NOMURA Kunio , MIYAZAKI Shigetake , SUETSUNA Junichi , KOBARI Kazumine , NAKATOMI Masao , HORIKAWA Hiromichi , KINJO Yutoku , AOKI Yoshio , MARUMO Kenji , HIRAGA Yomei , KIKUCHI Kohki , SAITO Atsushi , YAMAMOTO Asako , NAKAMURA Mitsunari , ASAKAWA Mitsuo , SUZUKI Akira , ISHII Yoshiro , TAKEBE Kazuo , SAGARA Morio , YOSHIDA Shuichiro , TAMURA Toyokazu , MURABAYASHI Hideya , YAMAGUCHI Keizo , TAMAZAWA Naoki , ONUMA Tomio , UEHARA Osamu , ENOOKA Gen , OKAMOTO Katsuhiro , MASAKI Naoyoshi , YANAGIYA Shigetoshi , TAKAHASHI Hiroshi , HONMA Mitsunobu , KANAZAWA Tomohiro , SUZUYAMA Yoji , TAKAHASHI Keiji , SASAKI Hideki , YASUI Shoji , IDA Shiro , NISHIOKA Kiyo , TAKISHIMA Tamotsu , AONUMA Seiichi , ONUMA Kikuo , WATANABE Akira , SASAKI Masako , SHIGENO Yoshiteru , OIZUMI Kotaro , KONNO Kiyoshi , HAYASHI Izumi , ABE Tatsuya , TAMAKI Shigeru , KATSU Masataka , OKUI Shinji , KAWAI Mieko , HIGASHI Fuyuhiko , IKEMOTO Hideo , NAKAMURA Isao , WATANABE Kazuyoshi , MASHIMO Keimei , UKAI Tetsuro , SHIMADA Kaoru , INAMATSU Takashi , URAYAMA Kyoko , TANIMOTO Hiroichi , NAKATANI Tatsuo , NAKATA Koichiro , NAKAMORI Yoshitaka , ODA Toshiro , CHONABAYASHI Naohiko , YOSHIMURA Kunihiko , KABE Junzaburo , ISHIBASHI Hiroyoshi , SANO Yasuyuki , UEDA Yasushi , SAITO Atsushi , SHIMADA Jingoro , SHIBA Kohya , YAMAJI Takehisa , OKUNO Kazuhiro , IHARA Hironobu , MIYAHARA Tadashi , NAKAGAWA Keiichi , KOYAMA Masaru , KIN KOUJIN , IIJIMA Fukuo , AKIYOSHI Ryuji , KAWAHARA Hiroyuki , YAMAMOTO Takashi , KOBAYASHI Hiroyuki , IWASAKI Hiromaru , TAKAMURA Kenji , KOHNO Kohta , MITA Seiji , KOBAYASHI Yoshio , FUJIMORI Ippei , ITO Akira , SHINDO Kunihiko , CHIBA Jun , NAGAOKA Shohei , FUKUSHIMA Kokichi

    新しいセフェム系抗生物質Ceftazidime (CAZ) の呼吸器感染症に対する有効性と安全性を客観的に評価する目的で, Cefotiam (CTM) を対照薬として, 二重盲検法により比較検討を行った.<BR>投与法は, 両薬剤とも1回1g (力価) を1日2回, 14日間点滴静注とし, 以下の成績を得た.<BR>1.小委員会判定による総合臨床床効果は, CAZ群で73 …

    Kansenshogaku Zasshi 58(7), 663-702, 1984

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  • Comparison of DL-8280 and Amoxicillin in the Treatment of Respiratory Tract Infections

    KOBAYASHI Hiroyuki , TANIMURA Kazunori , YAMAMOTO Toshiyuki , TORIKAI Katsutaka , ABE Yoichi , MAEKAWA Nobuo , NAKANISHI Michiyasu , IWATA Takekuni , OIDA Kazukiyo , AMITANI Ryoichi , MOCHIZUKI Yoshiro , TAGUCHI Yoshio , INOUE Mikio , INABA Nobuo , ODA Yoshiro , KAGIOKA Akira , TSUJINO Hiroyuki , NAKAI Hitoshi , ISHIHARA Kyosuke , SAKAMOTO Hiroko , YAMAGATA Yoko , MIKI Fumio , TAKAMATSU Kenji , SAITO Akira , OKAMOTO Yuruko , MAEHARA Keigo , YOSHIOKA Muneto , IIDA Yube , YASUNAGA Kohjiro , OKUBO Hiroshi , UEDA Yoshihiro , SOEJIMA Rinzo , NIKI Yoshito , NAKAHAMA Chikara , TOMIZAWA Masumi , WATANABE Masatoshi , HINO Jiro , KURIMURA Osamu , ARATANI Yoshihiko , SASAKI Hideo , FUKUHARA Hirofumi , NISHIMOTO Yukio , YAMAKIDO Michio , IWAMOTO Keiko , KODOMARI Naomi , NAKAYAMA Ichiro , TSUBURA Eiro , TAMURA Masakazu , OHGUCHI Hidetoshi , SAWAE Yoshiro , OKADA Kaoru , KUMAGAI Yukio , NAGANO Hitoshi , TSURUTANI Hideto , KISHIKAWA Reiko , ITOGA Takashi , HIRAGA Yomei , NASU Masaru , GOTO Jun , HARA Kohei , SAITO Atsushi , YAMAGUCHI Keizo , SUZUYAMA Yoji , SHIGENO Yoshiteru , WATANABE Koichi , NAKANO Masamoto , IKEBE Akira , KIKUCHI Kohki , Ishizaki Makoto , KOTEDA Tsunetoshi , MATSUMOTO Keizo , SHISHIDO Harumi , KUDO Kunio , KIMURA Hisao , ANDO Masayuki , SUGIMOTO Mineharu , SUGA Moritaka , FUKUDA Yasutsugu , YAMAMOTO Asako , TOKUNAGA Katsumasa , TOKUOMI Haruhiko , SHIMA Kiyoshi , HIGUCHI Sadanobu , TAKENAKA Shinobu , KOBARI Kazumine , NAKATOMI Masao , IRABU Yuei , TAKEBE Kazuo , ONUMA Tomio , TAKAMURA Kenji , TAMURA Toyokazu , YOSHIDA Shuichiro , OCHIAI Shigeru , KARIYA Katsutoshi , YAMANAKA Akiko , MASAKI Naoyoshi , OKAMOTO Katsuhiro , TAMURA Masao , ITO Takashi , NEMOTO Yoshikatsu , KONO Kota , SATOH Seiki , IDA Shiroh , TAKISHIMA Tamotsu , KONNO Kiyoshi , OIZUMI Kotaro , AONUMA Seiichi , HAYASHI Izumi , ABE Tatsuya , AOYAGI Teruo , KOIZUMI Yuichi , ONODERA Sokichi , KATSU Masataka , ADACHI Masanori , TAKEDA Hajimu , SEKINE Osamu , USUDA Yoshimaru , AOKI Nobuki , NITTA Isao , WATANABE Kyoko , YAMASAKU Fusanosuke , SUZUKI Yasutoshi , SASAKI Nobuhiro , SAITO Atsushi , SHIBA Kohya , MIYAHARA Tadashi , NAKAGAWA Keiichi , WATANABE Kentaro , KOYAMA Masaru , FUKUI Ko , MASHIMO Keimei , YAMANE Yoshiji , HANAOKA Kazuaki , NAGAHAMA Fumio , TANIMOTO Hiroichi , NAKAMORI Yoshitaka , CHONABAYASHI Naohiko , YOSHIMURA Kunihiko , NAKATANI Ryuo , NAKATA Koichiro , IKEMOTO Hideo , WATANABE Kazuyoshi , SHIMADA Kaoru , URAYAMA Kyoko , KAWAKAMI Yoshikazu , INAMATSU Takashi , FUNATSU Yuzo , HIGASHI Fuyuhiko , TAKIZAWA Takao , TAMAOKI Jun , KABE Junzaburo , ISHIBASHI Hiroyoshi , KATO Masako , ITO Toshio , FUJIMORI Ippei , HONMA Yukihiko , KOBAYASHI Yoshio , OBANA Mitsuo , ODAGIRI Shigeki , IKEDA Hirotada , SUZUKI Kaneo , MUROHASHI Kou , KANEKO Tamotsu , FUKAYA Kazufuto , MATSUMOTO Fumio , OYAMA Kaoru , MATSUZAKI Michiyuki , SUZUKI Kuninori , SHIMOKATA Kaoru , NISHIWAKI Keisuke , SAKAI Shuzo , MORISE Masanori , TOTANI Yasunobu , KATO Masahito , TAKEUCHI Toshihiko , HANAKI Hidekazu , KITAURA Saburo

    ピリドンカルボン酸系の合成経口抗菌剤DL8280の呼吸器感染症に対する有効性, 安全性及び有用性を検討する目的で, Amoxicillin (AMPC) を対照として二重盲検比較試験を実施した.<BR>対象疾患は慢性気管支炎, び漫性汎細気管支炎の感染性増悪及び気道感染を伴った慢性呼吸器疾患 (気管支拡張症, 気管支喘息, 肺気腫, 肺線維症, 陳旧性肺結核など) ならびに細菌性肺炎と …

    Kansenshogaku Zasshi 58(6), 525-555, 1984

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  • Enhancement of Antimicrobial Defense Activities of Immunoglobulins in Lung

    KAMEOKA Yoko , NAKAGAWA Masaru , TAMURA Masakazu , YASUOKA Isao , TSUBURA Eiro

    好中球による<I>E. coli</I>殺菌能に及ぼす, 免疫グロブリン (secretory IgA, monomeric IgA, monomeric IgG) および気管支・肺胞洗瀞液の影響について検討した.<BR>1. 免疫グロブリンによる<I>E. coli</I>殺菌能を検討した結果, <I>E. coli< …

    Kansenshogaku Zasshi 58(11), 1139-1143, 1984

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  • Comparative Study of the Effectiveness of Enoxacin and Amoxicillin on Bacterial Pneumonia by Double Blind Method

    MIKI Fumio , SASAKI Masako , SUZUKI Hiroshi , SHISHIDO Harumi , TSUCHIHASHI Kenji , RIKITOMI Naoto , ARAKI Yoshiro , ANDO Masayuki , SUGIMOTO Mineharu , SUGA Moritaka , SHIMA Kiyoshi , HIGUCHI Sadanobu , WATANABE Akira , TAKENAKA Shinobu , NASU Masaru , GOTO Jun , GOTO Yoichiro , TASHIRO Takayoshi , ITOGA Takashi , IRABU Yuei , KINJO Yutoku , NAKATOMI Masao , KOBARI Kazumine , ONUMA Kikuo , HAYASHI Izumi , AONUMA Seiichi , KATSU Masataka , MURAYAMA Yumiko , AOYAGI Teruo , HANYA Mantaro , NAGATOMI Hoichi , MIYAHARA Tadashi , SAITO Akira , SHIBA Kohya , IKEMOTO Hideo , WATANABE Kazuyoshi , KOBAYASHI Hiroyuki , OSHITANI Hiroshi , KAWAI Shin , SHIMADA Kaoru , INAMATSU Takashi , NAKAGAWA Keiichi , WATANABE Kentaro , TOMIZAWA Masumi , KOYAMA Masaru , KABE Junzabro , ISHIBASHI Hiroyoshi , TANIMOTO Hiroichi , CHONABAYASHI Naohiko , NAKAMORI Yoshitaka , YOSHIMURA Kunihiko , NAKATANI Tatsuo , NAKATA Koichiro , FUJIMORI Ippei , NAKAYAMA Ichiro , KOBAYASHI Yoshio , OBANA Mitsuo , FUKAYA Kazufuto , MATSUMOTO Fumio , ODAGIRI Shigeki , IKEDA Hirotada , SUZUKI Kaneo , MUROHASHI Kou , KANEKO Tamotsu , TAKEDA Hazimu , TAKEBE Kazuo , SEKINE Osamu , AOKI Nobuki , YAMASAKU Fusanosuke , SUZUKI Yasutoshi , OYAMA Kaoru , TAKEUCHI Toshihiko , KATO Masahito , HANAKI Hidekazu , YAMAMOTO Toshiyuki , MAEKAWA Nobuo , TAKASHIMA Tamotsu , NAKANISHI Michiyasu , MUTO Makoto , MURAYAMA Takako , SHIBATA Yasutaku , MIKAMI Riichiro , SAWAKI Masayoshi , KUNIMATSU Mikikazu , HAMADA Kaoru , FUJIMURA Masashi , CHOU Sumito , IDA Shiroh , OKAMOTO Yuruko , MAEHARA Keigo , UEDA Yoshiro , OKUBO Hiroshi , TAKAMATSU Kenji , SOEJIMA Rinzo , NIKI Yoshihito , AISAKA Tadakazu , TUBURA Eiro , TAMURA Masakazu , KONNO Kiyoshi , OGUCHI Hidetoshi , SAWAE Yoshiro , OKADA Kaoru , KUMAGAI Yukio , HARA Kohei , SAITO Atsushi , IZUMIKAWA Kinichi , YAMAGUCHI Keizo , SUZUYAMA Yoji , SHIGENO Yoshiteru , OIZUMI Kotaro , WATANABE Koichi , KOMORI Munetaka , YAMASHITA Kyoko , MIYAZAKI Yukishige , OE Toshiyuki , OKA Rokushi , OKUNO Kazuhiro , SAI Masao , UEDA Yasuko , MATSUMOTO Keizo

    Enoxacin (以下ENXと略す) の細菌性肺炎に対する有効性と安全性を, Amoxicillin (以下AMPCと略す) を対照薬剤とし, 二重盲検法により比較検討した.<BR>肺炎存在明確な16歳以上の患者を対象とし, ENX (1日600mg) またはAMPC (1日1g) を原則として14日間経口投与し, 以下の成績を得た.<BR>1) 全体の採用症例数は139 …

    Kansenshogaku Zasshi 58(10), 1083-1113, 1984

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  • Comparative Clinical Study of Enoxacin (AT-2266, ENX) and Cefaclor (CCL) for Chronic Respiratory Tract Infections by a Double-Blind Method

    HARA Kohei , MIYAZAKI Yukishige , FUKUHARA Hirofumi , TUBURA Eiro , TAMURA Masakazu , OGUCHI Hidetoshi , SAWAE Yoshiro , OKADA Kaoru , KUMAGAI Yukio , MATSUMOTO Keizo , SUZUKI Hiroshi , SHISHIDO Harumi , OE Toshiyuki , TSUCHIHASHI Kenji , RIKITOMI Naoto , ARAKI Yoshiro , ANDO Masayuki , SUGIMOTO Mineharu , SUGA Moritaka , SHIMA Kiyoshi , HIGUCHI Sadanobu , TAKENAKA Shinobu , NASU Masaru , SAI Masao , GOTO Juyn , GOTO Yoichiro , TASHIRO Takayoshi , IRABU Yuuei , NAKATOMI Masao , KOBARI Kazumine , UEDA Yasuko , SAITO Akira , TOMIZAWA Masumi , NAKAYAMA Ichiro , TAKEBE Kazuo , TAKISHIMA Tamotsu , IDA Shiroh , SAITO Atsushi , KONNO Kiyoshi , OIZUMI Kotaro , SASAKI Masako , WATANABE Akira , ONUMA Kikuo , AONUMA Seiichi , HAYASHI Izumi , ABE Tatsuya , KATSU Masataka , MURAYAMA Yumiko , IZUMIKAWA Kinichi , AOYAGI Teruo , HANYA Mantaro , NAGATOMI Hoichi , MIYAHARA Tadashi , SHIBA Kohya , IKEMOTO Hideo , WATANABE Kazuyoshi , KOBAYASHI Hiroyuki , OSHITANI Hiroshi , KAWAI Shin , YAMAGUCHI Keizo , MASHIMO Keimei , YAMANE Yoshiji , MATSUMOTO Koichi , SHIMADA Kaoru , INAMATSU Takashi , NAKAGAWA Keiichi , WATANABE Kentaro , KOYAMA Masaru , KABE Junzaburo , ISHIBASHI Hiroyoshi , SUZUYAMA Yoji , TANIMOTO Hiroichi , CHONABAYASHI Naohiko , NAKAMORI Yoshitaka , YOSHIMURA Kunihiko , NAKATANI Tatsuo , NAKATA Koichiro , FUJIMORI Ippei , KOBAYASHI Yoshio , OBANA Mitsuo , FUKAYA Kazufuto , SHIGENO Yoshiteru , MATSUMOTO Fumio , ODAGIRI Shigeki , IKEDA Hirotada , SUZUKI Kaneo , MUROHASHI Kou , KANEKO Tamotsu , TAKEDA Hazimu , SEKINE Osamu , AOKI Nobuki , YAMASAKU Fusanosuke , WATANABE Koichi , OYAMA Kaoru , TAKEUCHI Toshihiko , KATO Masahito , HANAKI Hidekazu , YAMAMOTO Toshiyuki , MAEKAWA Nobuo , NAKANISHI Michiyasu , SHIBATA Yasutaku , NISHIYAMA Hideki , MIKAMI Riichiro , KOMORI Munetaka , SAWAKI Masayoshi , KUNIMATSU Mikikazu , HAMADA Kaoru , FUJIMURA Masashi , CHOU Sumito , MIKI Fumio , OKAMOTO Yuruko , OKUBO Hiroshi , MAEHARA Keigo , TAKAMATSU Kenji , YAMASHITA Kyoko , SOEJIMA Rinzo , NIKI Yoshihito , NAKAHAMA Tsutomu , WATANABE Masatoshi , YAMAKIDO Michio , TSUKIYAMA Fumiaki , NOMURA Toshiya , AISAKA Tadakazu , KURIMURA Osamu , SASAKI Hideo

    慢性気道感染症に対するEnoxacin (AT-2266, ENX) とCefaclorの臨床効果と副作用を比較検討する目的で, 全国40施設の協同研究として二重盲検比較試験を行い, 以下の成績を得た.<BR>1) 慢性気道感染症に対するEnoxacinl日600mgとCefaclorl日750mgの臨床効果については, 両群間に有意な差は認められなかった.<BR>2) 細 …

    Kansenshogaku Zasshi 58(10), 1046-1072, 1984

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  • Therapeutic Evaluation on Combination Therapy with IG-100, pH4-Treated Human Immunoglobulin Preparation for i.v. Administration, and Antibiotics Against Severe Infections

    MATSUMOTO Keizo , MIKUNI Chikara , KUBO Akemi , YONEZAWA Tsuyoshi , KANAYAMA Yoshio , SHIBATA Hirotoshi , SAKAI Katsuji , UEDA Takami , KITANI Teruo , KONISHI Ichiro , YASUNAGA Kojiro , OKAMOTO Yuruko , TAKEBE Kazuo , MAEHARA Keigo , UEDA Yoshihiro , HORIUCHI Atsushi , HASEGAWA Hirofumi , UCHINO Haruto , SAWADA Hiroyoshi , NAKAYAMA Shiro , NAGAI Kenichi , NAGAI Kiyoyasu , KANAMURA Akihisa , OKAMOTO Katsuhiro , YOSHIYASU Soichiro , HATTORI Takao , NIIMOTO Minoru , MIYOSHI Yukihisa , HAMAMOTO Sadanori , TANADA Minoru , NAKANE Hideyuki , SOEJIMA Rinzo , NIKI Yoshito , NAKAHAMA Chikara , YOSHIDA Shuichiro , KANEKO Toshio , SHINOHARA Kenji , KAKU Kohei , TSUBURA Eiro , TAMURA Masakazu , KUSABA Tomohiro , NIHO Yoshiyuki , OKAMURA Seiichi , TAKII Masahide , ONO Michio , KARIYA Katsutoshi , HARA Kohei , SAITO Atsushi , YAMAGUCHI Keizo , SUZUYAMA Yoji , SHIGENO Yoshiteru , TOMITA Hiroshi , NAGASAWA Masao , ICHIMARU Michito , IKEDA Shuichi , HARADA Tomoyuki , TOYAMA Yoko , NAGATAKE Tsuyoshi , ARAKI Shukuro , Ando Masayuki , SUGIMOTO Mineharu , SUGA Moritaka , ONUMA Tomio , NAKAMURA Teruo , OSONOI Takeshi , OCHIAI Shigeru , MASAOKA Toru , SAGARA Morio , YANAGIYA Shigetoshi , UEHARA Osamu , MASAKI Naoyoshi , TAMURA Toyokazu , TAMURA Masao , ITO Takashi , NEMOTO Yoshikatsu , KONNO Kiyoshi , OIZUMI Kotaro , NAKAMURA Toru , WATANABE Akira , KARIYONE Shigeo , UCHIKA Tatsumi , MATSUDA Shin , MAEKAWA Tadashi , SHINONOME Shogo , MIURA Yasusada , SAKAMOTO Shinobu , TSUBOYAMA Akihiro , MIWA Shiro , SHIMADA Kaoru , MIYAHARA Tadashi , SHIMADA Jingoro , TANIMOTO Hiroichi , NAKAMORI Yoshitaka , CHONABAYASHI Naohiko , KATSUNUMA Hideyo , MIYAMOTO Yoshinori , KABE Junzaburo , MIYAMOTO Yasufumi , OKABE Kazuko , URUSHIZAKI Ichiro , MASHIMO Keimei , YAMAOKA Sumio , UKAI Tetsuro , UENO Katsunori , NAKAGAWA Keiichi , KIN Kohjin , IIJIMA Fukuo , ABE Takeshi , KINOSHITA Tadatoshi , MATSUDA Jyuzo , KOGO Yutaka , KAWASUGI Kazuo , OYAMA Toshiro , AMAKI Ichita , OSHIMA Toshiteru , TAKEO Hiroshi , KOBAYASHI Hiroyuki , TAKEDA Hiroaki , KAWAI Shin , TERADA Hideo , HAGIWARA Shoji , SAITO Akira , NIIKURA Haruo , MATSUNO Kazuhiko , MORI Hiraku , KIN Kunikane , TAKIZAWA Yoshio , FUJIMORI Ippei , KOBAYASHI Yoshio , ONAKA Akio , NAKAMURA Hiroshi , SHIBATA Akira , TOMIZAWA Masumi , MORIYAMA Yoshiaki , TAKEDA Hajime , SEKINE Osamu , OYAMA Kaoru , KANAKI Michiko , HATTORI Kenichi , YOSHIDA Takashi , TAKEUCHI Toshihiko , KATO Masahito , YAMAMOTO Toshiyuki , NAKAYANA Ichiro , SUZUKI Kanzo , HANAKI Hidekazu , YAMAMOTO Motoko , YURA Jiro , SHINAGAWA Nagao , TAKAOKA Tetsuro , NAKAMURA Akishige , HIROTA Yutaka , FUJIWARA Yoshihisa , SASADA Masataka

    IG-100はスイス赤十字社により開発された静注用ヒト免疫グロブリン製剤であり, Cohnのエタノール分画法に基づきpH4処理により調製される. 本邦では1982年以来, 抗生剤療法に抵抗性の重症細菌感染症並びに重症真菌感染症に対するIG-100の臨床的検討が行なわれてきた.<BR>IG-100の投与を受けた340例の患者のうち, 安全性評価に供された症例は332例 (97.6%) で …

    Kansenshogaku Zasshi 58(10), 1001-1024, 1984

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  • CLINICAL STUDIES ON AC-1370

    TAMURA MASAKAZU , GOTO TOSHIHIRO , TAKISHITA YOSHIHIRO , TSUBURA EIRO

    新しいセファロスポリン剤であるAC-1370を内科的感染症7例に投与し, その臨床的効果, 副作用について検討した。<BR>対象は呼吸器感染症6例, 胆道感染症1例であっな。そのうち4例は基礎疾患を有していた。投与方法は1回0.5~1.0gを1日2回, 7~25日間one shot静注した。臨床効果の判定は, 著効, 有効, 無効の3段階にて行った。臨床効果の内訳は, 呼吸器感染症6例 …

    CHEMOTHERAPY 32(Supplement9), 407-410, 1984

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  • STUDIES ON THE ENHANCEMENT OF ANTIMICROBIAL DEFENCE ACTIVITIES OF AC-1370 AND ITS DERIVATIVES

    KAMEOKA YOKO , MUTSUURA SEIJI , YOSHIMOTO SACHIKO , TAMURA MASAKAZU , TSUBURA EIRO

    新抗生物質AC-1370 (以下AC) が, <I>in vitro</I>効果以上に<I>in vivo</I>での感染防禦効果を示すため, 抗菌作用以外のACのもつ宿主賦活作用について検討した。ACを加水分解し, 抗菌活性を除いた物質 (H-AC) およびACの誘導体について, <I>E.coli</I>感染に対する防禦効 …

    CHEMOTHERAPY 32(Supplement9), 103-107, 1984

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  • CLINICAL STUDIES ON CEFTRIAXONE (Ro 13-9904)

    TAMURA MASAKAZU , GOTO TOSHIHIRO , TAKISHITA YOSHIHIRO , TSUBURA EIRO

    新しいセフェム系抗生剤てあるceftriaxone (CTRX, Ro 13-9904) を内科的感染症8例に投与し, その臨康的効果, 副作用について検討したので報告する。<BR>対象は呼吸器感染症5例, 尿路感染症2例, 敗血症疑い1例で, いすれも気管支喘息, 肺癌等何らかの基礎疾患を有する症例である投与は, 1日2~4g, 6日から18日間one shot静注した。臨床効果の判 …

    CHEMOTHERAPY 32(Supplement7), 424-426, 1984

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