松本 行雄 Matsumoto Yukio

ID:9000256183207

国立霞ヶ浦病院内科 Department of Internal Medicine, Kasumigaura National Hospital (1996年 CiNii収録論文より)

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  • COMPARATIVE STUDY ON THE EFFICACY OF RITIPENEM ACOXIL AND CEFOTIAM HEXETIL IN CHRONIC LOWER RESPIRATORY TRACT INFECTIONS BY THE DOUBLE-BLIND METHOD  [in Japanese]

    SAITO ATSUSHI , OHSAKI YOSHINOBU , NISHIYAMA HIDEKI , SUGITA TAKAKAZU , HORIKAWA SADAO , KISHIMOTO TADAMITSU , TANIO YOSHIRO , IKEDA AKINORI , ITO MASAMI , OKUMOTO TAKESHI , YONEZU SEIBUN , MIKI FUMIO , MATSUMOTO HIROYUKI , OKAWA KENTARO , NAKAJIMA SHIGENORI , NARITA NOBUHIRO , SAWAKI MASAYOSHI , MIKASA KEIICHI , HIGASHINO KAZUYA , NAKANO TAKASHI , MAEBO AKIO , YOSHIMOTO TAKAHIKO , SONODA TAKASHI , INOUE HIROSHI , NOMURA SHIGEO , YAMAGUCHI KAZUYUKI , TOKUMOTO HIROSHI , NAKAGAWA MASAKIYO , HIRABAYASHI MASATAKA , TOGAWA NAOKI , YOSHIDA MASAO , KAWAI YOSHITAKA , SOEJIMA RINZO , OKIMOTO JIRO , YOSHIDA MASAMI , MATSUSHIMA TOSHIHARU , KIMURA MAKOTO , SASAKI TAKAO , MATSUMOTO YUKIO , YAMAKIDO MICHIO , ISHIOKA SHINICHI , KUWAHARA MASAO , MOCHIZUKI NOBUHIRO , MIYAZAWA TERUOMI , YANAGIDA JITSURO , MOURI TAKASHI , ARITA KENICHI , DAIDO KAZUHIRO , EJIMA TSUYOSHI , SONE SABURO , TANI KENJI , MIKI SATOSHI , SAWAE YOSHIRO , TAKAKI KOJI , YOSHIDA MINORU , ARITOMI TAKAMICHI , KOBAYASHI HITOSHI , OIZUMI KOTARO , ICHIKAWA YOICHIRO , SHIRAISHI TSUNEAKI , KAWAHARA MASASHI , KAWAGUCHI SHINZO , KAWAYAMA TOMOTAKA , SATO YOSHIHIRO , HONDA YOSHIAKI , ISHIBASHI TSUNEO , TAKAMOTO MASAHIRO , ITO TAKASHI , KAJIKI AKIRA , HARADA YASUKO , YAMADA HOZUMI , FUJISAWA NOBUMITSU , ANDO MASAYUKI , SUGA MORITAKA , DOI TOSHINORI , TOKUNAGA KATSUMASA , SHIMA KIYOSHI , TAKENAKA SHINOBU , BANDO TAKESHI , HARA KOHEI , KOHNO SHIGERU , KAKU MITSUO , KOGA NOBUHIRO , INOUE YUICHI , YAMASHITA YUKO , SAKATA SHINGO , FUJII TAKESHI , IRIFUNE KENJI , SHIMOGUCHI KAZUNORI , TAKEUCHI KENICHI , MIYAZAKI YOSHITSUGU , WATANABE TAKASHI , SOEJIMA YOSHIFUMI , MATSUMOTO KEIZO , NAGATAKE TSUYOSHI , SAKAMOTO TASUKU , TAO MISAO , YAMASHITA HIROSHI , TAKASUGI MASAKAZU , AKIYAMA MORITOSHI , HIRANO HARUTO , FUJISHITA MIKIO , NASU MASARU , YAMASAKI TOHRU , GOTO YOICHIRO , NAKAMA KAORU , INOUE SOICHI , MATSUKURA SHIGERU , MASHIMOTO HIDEO , MUKAE HIROSHI , SAITO ATSUSHI , SAITO AKIRA , TANIFUJI YUKIO , FUKUHARA HIROSHI , TATEYAMA MASAO , OYAKAWA TOMINORI , DEGUCHI KOICHI , NAKASHIMA MITSUYOSHI , TANNO YASUO , SHIRATO KUNIO , TAKAHASHI MAKOTO , SAKAMOTO MASAHIRO , NUKIWA TOSHIHIRO , WATANABE AKIRA , SATO KAZUO , NAKAMURA TOSHIO , YANASE KENJI , KAWAKAMI YOSHIKAZU , DOTE KUNIO , HOMMA MITSUNOBU , ITO NOBUO , OHISHI AKIRA , FUKUDA KIYOSHI , NAKAZAWA ATSUSHI , KATSU MASATAKA , KOBAYASHI HIROYUKI , SAKAYORI SUSUMU , MIURA HIROSHI , YAMAGUCHI ETSURO , WATANABE HIDEHIRO , SHIMADA KAORU , OKA SHINICHI , SUGIYAMA HIROTAKA , INAMATSU TAKASHI , SANO YASUYUKI , ARAI YASUO , OTOMO MAMORU , KOBAYASHI HIDEO , KURAKI TAKASHIGE , KOBA HIROYUKI , TANAKA HIROYUKI , SHISHIDO HARUMI , TANOUE SHOKO , TSUCHIHASHI KEIKO , HAYASHI IZUMI , KOYAMA MASARU , KUDO KOICHIRO , KOSHINO TAKESHI , AKIYAMA JUN , OKUBO TAKAO , ABE SHOSAKU , TANI KENJI , IKEDA HIROTADA , SHOJI AKIRA , CHIBA JUN , ONO SHIGERU , HONDA ATSURO , IKEHARA KUNIHIKO , IRIMAJIRI SHOICHIRO , MATSUOKA YASUO , OBANA MITSUO , OHMICHI MITSUHIDE , MATSUMOTO FUMIO , SAKURAI IWAO , ODAGIRI SHIGEKI , OGURA TAKASHI , TAKAHASHI HIROSHI , ARAKAWA MASAAKI , WADA KOICHI , IWATA FUMIHIDE , SHIMAZU YOSHINORI , SEGA HIROYUKI , HIRAGA YOHMEI , TSUKADA HIROKI , KAWASHIMA TAKASHI , AOKI NOBUKI , SUZUKI YASUTOSHI , SEKINE OSAMU , SATO ATSUHIKO , CHIDA KINGO , IWATA MASATOSHI , SHICHI IZUMI , YASUDA KAZUMASA , KIKUCHI KENJIRO , TORIKAI KATSUTAKA , TAKAGI KENZO , WATANABE YOSHIAKI , TANIGUCHI HIROYUKI , YAMASHITA NAOHIRO , USUI ISAO , IZUMI SABURO , KUZE FUMIYUKI , BANDO KENJI , OHYAMA SHINICHIRO

    新しく開発されたペネム系経口抗生剤, Ritipenem acoxil (RIPM-AC) の慢性下気道感染症に対する有効性, 安全性および有用性を客観的に評価するたあ Cefotiamhexeti1 (CTM-HE) を対照薬として多施設二重盲検群間比較試験を行った。RIPM-ACは1同200mgを, CTM-HEは1回400mgをそれぞれ1日3回, 原則として14日間連続経口投与した。< …

    The Japanese Journal of Antibiotics 49(3), 219-249, 1996

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  • Study on Azithromycin in Treatment of Diffuse Panbronchiolitis

    KOBAYASHI Hiroyuki , SHIMADA Kaoru , SANO Yasuyuki , ARAI Yasuo , SHISHIDO Harumi , WATANABE Hisashi , SAKAMOTO Eriko , NAKATA Koichiro , NAKATANI Tatsuo , TSUBOI Nagayasu , ODAGIRI Shigeki , TAKEDA Hiroaki , SUZUKI Kaneo , YOSHIIKE Yasuhiro , HIRAI Yoshihiro , OKUBO Takao , IKEDA Hirotada , ARAKAWA Masaaki , WADA Kouichi , TSUKADA Hiroki , SATO Atsuhiko , CHIDA Kingo , SAKAYORI Susumu , NARITA Nobuhiro , SAWAKI Masayoshi , MIKASA Keiichi , SOEJIMA Rinzo , NIKI Yoshihito , OKIMOTO Niro , SASAKI Takao , MATSUMOTO Yukio , SUGIMOTO Yuji , KIDO Masamitsu , KAWAKAMI Yoshikazu , NIKAIDO Yoshihiko , ARAKAWA Kikuo , KOHNO Kenji , ISHIBASHI Tsuneo , TAKAMOTO Masahiro , KITAHARA Yoshinari , HARA Kohei , KOHNO Shigeru , KADOTA Junichi , NASU Masaru , OTSUKA Yoshinori , GOTO Yoichiro , YAMASAKI Tohru , SAITO Atsushi , FUKUHARA Hiroshi , INADOME Jun , TAMURA Masashi , KONISHI Kazuki , TANIMOTO Shinichi , FUKAKUSA Motonori

    びまん性汎細気管支炎を対象に, 新規の15員環マクロライド系抗生物質azithromycin (AZM) の有効性, 安全性を検討した.<BR>合計60例の症例にAZM250mgを1週2回, 原則として3カ月間間欠投与し, 臨床効果52例, 安全性55例を検討の対象とした.<BR>AZM投与による有効率は84.6%(44/52) であった.投与12週後の臨床所見では, 喀痰 …

    Kansenshogaku Zasshi 69(6), 711-722, 1995

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  • Fundamental and clinical studies of azithromycin against respiratory infection  [in Japanese]

    Matsumoto Yukio , Sugimoto Yuji , Yamazaki Seiji , Sakata Takuya , Hitsuda Yutaka , Sasaki Takao

    新しい経口アザライド系抗菌薬azithromycinの呼吸器感染症起炎菌に対する抗菌力と, 呼吸器感染症に対する臨床効果ならびに安全性について検討し, 下記の結果を得た。<BR>呼吸器感染症の臨床分離株に対する本剤のMICは, <I>Staphylococcus aureus</I>では0.39~>100μg/ml (MIC<SUB>90< …

    Japanese Journal of Chemotherapy 43(Supplement6), 245-249, 1995

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  • Basic and clinical studies on biapenem in respiratory tract infections

    Sugimoto Yuji , Matsumoto Yukio , Sakata Takuya , Teramoto Hidemi , Konishi Tatsuya , Chikumi Hiroki , Yamasaki Seiji , Hitsuda Yutaka , Sasaki Takao

    新しいカルバペネム系抗生物質biapenem (BIPM) の呼吸器病原菌に対する抗菌力と, 呼吸器感染症に対する臨床効果及び有用性について検討を行い, 下記の結果を得た。<BR>呼吸器臨床分離菌に対する本剤のMIC<SUB>80</SUB>は, methicillin-sensitive <I>Staphylococcus aureus</I …

    CHEMOTHERAPY 42(Supplement4), 377-380, 1994

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  • Basic and clinical studies of tazobactam/piperacillin in respiratory infections

    Konishi Tatsuya , Sugimoto Yuji , Matsumoto Yukio , Sakata Takuya , Teramoto Hidemi , Chikumi Hiroki , Yamasaki Seiji , Hitsuda Yutaka , Sasaki Takao

    新しいβ-lactamase阻害剤であるtazobactamとpiperacillinの合剤であるtazobactam/piperacillinの呼吸器病原菌に対する抗菌力と, 呼吸器感染症に対する臨床的効果並びに有用性について検討し, 下記の結果を得た。<BR>呼吸器感染症の臨床分離株に対する本剤のMIC<SUB>90</SUB>はmethicillin-se …

    CHEMOTHERAPY 42(Supplement2), 433-436, 1994

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  • Basic and clinical studies of loracarbef in respiratory infections

    Matsumoto Yukio , Sugimoto Yuji , Chikumi Hiroki , Sakata Takuya , Konishi Tatsuya , Teramoto Hidemi , Hitsuda Yutaka , Sasaki Takao

    はじめての経口用カルバセフェム系抗生物質loracarbefの呼吸器感染症病原菌に対する抗菌力と, 呼吸器感染症における臨床効果ならびに有用性について検討し, 下記の結果を得た。<BR>呼吸器感染症患者より分離された臨床株に対する本剤のMICは, <I>Haemophilus influenzae</I>では0.39~1.56μg/ml (MIC<SUB& …

    CHEMOTHERAPY 41(Supplement3), 223-226, 1993

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  • Basic and clinical studies on temafloxacin in respiratory infections

    Matsumoto Yukio , Sugimoto Yuji , Teramoto Hidemi , Konishi Tatsuya , Chikumi Hiroki , Sakata Takuya , Hitsuda Yutaka , Sasaki Takao

    新しい経口ピリドンカルボン酸系抗菌剤temafloxacin (TMFX) の呼吸器病原菌に対する抗菌力と, 呼吸器感染症に対する臨床的効果ならびに有用性について検討し, 下記の結果を得た。<BR>呼吸器感染症の臨床分離株に対する本剤のMIC<SUB>80</SUB>は, methicillin-sensitive <I>Staphylococcus …

    CHEMOTHERAPY 41(Supplement5), 409-416, 1993

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  • A Comparative Study of Cefepime for Bacterial Pneumonia

    SAITO Atsushi , FUJITA Yuka , TERAMOTO Hidemi , YAMAKIDO Michiro , HASEGAWA Kenji , TSUYA Takashi , SADAMOTO Kenichiro , KUWABARA Masao , OKADA Masanobu , ARITA Kenichi , DOI Masao , DAIDO Kazuhiro , HIROSHIMA Takashi , YANAGIDA Jitsuro , WATANABE Kenichiro , ATA Yuichi , SUGIHARA Motohiro , YUKUTAKE Masato , AWAYA Kouichi , IHARA Yoshihisa , SAWAE Yoshihiro , SHIMONO Nobuyuki , KUMAGAI Yukio , SAKAI Eiichi , HIROSE Takahito , SATO Kei , OHIZUMI Kohtaro , ICHIKAWA Youichiro , TANAKA Masako , MITSUTAKE Yoshiyuki , FUJINO Kazuma , KUBUSHIRO Mikio , HIGASHI Toshihiro , HARA Kohei , SAITO Akira , KOHNO Shigeru , KOGA Hironobu , KAKU Mitsuo , MATSUMOTO Keizo , OHISHI Kazunori , SHIMA Kiyoshi , TAKENAKA Shinobu , NASU Masaru , GOTO Yoichiro , YAMAZAKI Tohru , NAKAYAMA Ichiro , NAGAI Hiroyuki , TASHIRO Takayoshi , NAGAOKA Hiroshi , NAKAMA Kaoru , OGAWA Nobuya , KUSANO Nobuchika , HIRAGA Yohmei , OHMICHI Mitsuhide , TAKEBA Kazuo , OSONOI Ken , SAITO Miyoko , SHIGENO Yoshiteru , KURODA Hirohisa , TAMURA Masao , KONISHI Kazuki , MORI Yoshiaki , OBARA Akiho , OBARA Kazuo , KOBAYASHI Hitoshi , OGAWA Junichi , KUDO Kunio , ISHII Munehiko , IRABU Yuei , MOTOMIYA Masakichi , WATANABE Akira , HONDA Yoshihiro , TOKUE Yutaka , HONMA Mitsunobu , KATSU Masataka , KUGA Keisuke , KABE Junzaburou , ARIOKA Hitoshi , ARIOKA Hiroko , FUKUHARA Hiroshi , KOYAMA Masaru , NAKATA Kouichiro , NAKAMORI Yoshitaka , SAKAI Osamu , SHIMADA Jingorou , SHIBA Kohya , YOSHIDA Masaki , TANIMOTO Hiroichi , OBARA Kazuo , OKAMURA Tetsuo , ONODERA Soukichi , KOBAYASHI Hiroyuki , SAKAYORI Toru , OSHITANI Hiroshi , TAKEDA Hiroaki , IRIMAJIRI Shoichiro , MATSUOKA Yasuo , OBANA Mitsuo , OKUBO Takao , IKEDA Hirotada , MATSUMOTO Fumio , NAKANO Hitoshi , SAKURAI Iwao , TAKAHASHI Takayuki , ODAGIRI Shigeki , TAKAHASHI Hiroshi , TAKAHASHI Kenichi , AMANO Yasutsugu , SAKUMA Takashi , ARAKAWA Masaaki , WADA Koichi , KAWASHIMA Takashi , SHIMIZU Tetsuo , TAKATO Masanaga , HOSHINO Shigeyuki , SEKINE Osamu , SUZUKI Yasutoshi , TAKEUCHI Toshihiko , HAYASHI Yoshimitsu , YAMAMOTO Kazuhide , YAMAMOTO Toshihiko , SUZUKI Kanzo , MATSUURA Toru , SASAKI Nobuhiro , ADACHI Satoru , KUZE Fumiyuki , MURAYAMA Takako , INABA Nobuo , ODA Yoshio , KAGIOKA Akira , MIKI Fumio , SOEJIMA Rinzo , NIKI Yoshihito , HINO Jiro , HASHIZUME Hirotaka , SUMI Masaru , MATSUSHIMA Toshiharu , KAWANISHI Masayoshi , KIMURA Makoto , HIRAKI Shunkichi , WATANABE Yohichi , ARAKI Masashi , SASAKI Takao , MATSUMOTO Yukio , SUGIMOTO Yuji

    新しい注射用セフェム系抗生物質Cefepime (CFPM) の細菌性肺炎に対する有効性, 安全性および有用性を検討するためCeftazidime (CAZ) を対照薬として比較試験を実施した. CFPMおよびCAZの投与量はともに1回1.0g (力価), 1日2回, 点滴静注にて原則として14日間投与とし, 以下の結果を得た.<BR>1. 総投与症例183例中臨床効果判定可能症例14 …

    Kansenshogaku Zasshi 66(7), 859-885, 1992

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  • A Comparative Study between cefpirome (CPR) and ceftazidime (CAZ) in Respiratory Tract Infections

    SOEJIMA Rinzo , SAITO Akira , SAKURAI Iwao , IMAI Takeo , MATSUMOTO Fumio , ODAGIRI Shigeki , MATSUMURA Masanori , SUZUKI Kaneo , MUROHASHI Kou , TAKAHASHI Hiroshi , TAKAHASHI Kenichi , YOSHIOKA Teruaki , TOMIZAWA Masumi , KOYAMA Izumi , OGURA Takashi , ARAKAWA Masaaki , WADA Koichi , KAWASHIMA Takashi , TAKATO Masanaga , KUMANO Hidenori , AOKI Nobuki , SATAKE Tatsuo , YAMAKI Kenichi , NAKAYAMA Ichiro , SUZUKI Ryujiro , TAKAGI Kenzo , TANAKA Hitoshi , IMAI Masatoshi , TSUNODA Toshiaki , WATANABE Yoshiaki , TAKEUCHI Toshihiko , HAYASHI Yoshimitsu , YAMAMOTO Kazuhide , YAMADA Yasuo , SHIBAKI Hidetoshi , KUZE Fumiyuki , MURAYAMA Takako , SUZUKI Katsuhiro , KATO Motokazu , CHIBA Masaru , YAMAGUCHI Riyo , NAGAI Hitoshi , UMEDA Fumikazu , TOMIOKA Hiromi , EBISUI Osamu , TANEICHI Koji , IWASAKI Hironobu , BANDO Kenji , NISHIMURA Takashi , OYAIZU Tatsuki , ISHIDA Sunao , OHSHIMA Shunsaku , KADO Masao , YASUBA Hirotaka , SUGIMOTO Kikuo , YONEZU Seibun , KIKUIRI Tsuyoshi , UEDA Yoshihiro , YASUNAGA Kojiro , MIKI Fumio , TSUBURA Eiro , NAKAGAWA Masaru , OGURA Takeshi , OGUSHI Fumitaka , KAWANISHI Masashi , ICHIKAWA Waka , MIZUNO Kazuhito , SHINOHARA Masahide , ISHIKAWA Seiko , TAKISHITA Yoshihiro , BANDO Hiroyasu , HASHIMOTO Yoshihiro , NARITA Nobuhiro , SAWAKI Masayoshi , MIKASA Keiichi , KONISHI Mitsuru , MATSUSHIMA Toshiharu , KIMURA Makoto , MIWA Akira , KAWANISHI Masayasu , KURIMURA Tadasu , SASAKI Hideo , FUKUHARA Hirofumi , SASAKI Takao , MATSUMOTO Yukio , SUGIMOTO Yuji , SAWAE Yoshiro , ISHIMARU Toshiyuki , TAKAGI Koji , ITO Choei , SHIMONO Nobuyuki , SHIGEMATSU Nobuaki , YAGAWA Katsuro , HAYASHI Shinichiro , KONO Kenji , ONUKI Keisuke , TOHARA Shinichi , TAKEDA Seiji , TAKII Masahide , OKUDAIRA Katsumi , SATO Mitsuo , SAKAUE Akihiko , SHINOHARA Koichi , OIZUMI Kotaro , ICHIKAWA Yoichiro , KAWAHARA Masashi , HARA Kohei , HIROTA Masaki , YAMAGUCHI Keizo , KONO Shigeru , KOGA Hironobu , SUMI Masaru , SUZUKI Akira , KAKU Mitsuo , DOTSU Yasumasa , YAMADA Hiroshi , FUKUSHIMA Kiyoyasu , SUYAMA Naofumi , HAYASHI Toshiaki , MATSUMOTO Keizo , YOSHIDA Toshiaki , NAGATAKE Tsuyoshi , AKIYAMA Moritoshi , HONDA Yasuhito , TAKASUGI Masakazu , TAGUCHI Mikio , WATANABE Kiwao , SHISHIDO Harumi , SHIMA Kiyoshi , TAKENAKA Shinobu , NASU Masaru , GOTO Jun , SHIGENO Hideaki , GOTO Yoichiro , SEKINE Kyuichiro , TASHIRO Takayoshi , NAGAI Hiroyuki , YAMAZAKI Toru , AKASHI Mitsunobu , SAITO Atsushi , FUKUHARA Hiroshi , KANESHIMA Hiroshi , IRABU Yuei , SHIMOJI Katsuyoshi , KITSUKAWA Keizo , HIRAGA Yomei , SHIGENO Yoshiteru , OGAWA Nobuya , OMICHI Mitsuhide , YASUDA Shinya , KOROKU Tetsuji , ITO Susumu , KASAGI Shoji , ONODERA Sokichi , HINO Jiro , OSAKI Yoshinobu , MATSUMOTO Hiroyuki , OTA Takafumi , SAKAI Eiichi , SHIMIZU Tetsuo , SASAKI Nobuhiro , FUJIKANE Toshiaki , FUJIUCHI Satoshi , SHISHIDO Toshiaki , TAKEBE Kazuo , OKIMOTO Niro , YANADA Atsuko , MASUDA Mitsuo , MURAKAMI Seiichi , IMAMURA Kenichi , TAMURA Toyokazu , ENDO Katsumi , MURABAYASHI Hideya , OCHIAI Shigeru , SAWADA Hidekazu , SHIMURA Michitaka , KAWAKAMI Yoshikazu , TAMURA Masashi , KONISHI Kazuki , YOSHIDA Taiji , SUDO Morio , BANDO Takeshi , SATO Nobuhisa , OURA Masayuki , UNOURA Tetsuro , MOURI Takashi , TAKISHIMA Tamotsu , YAMAGUCHI Etsuro , TANNO Yasuo , KUDO Kunio , ISHII Munehiko , SUGIYAMA Masaharu , MOTOMIYA Masakichi , WATANABE Akira , NAGAI Kosaku , SATO Kazuo , KONNO Kiyoshi , HASUIKE Teruo , TERAI Tsugio , SHIDA Kuniharu , SHINDO Satoshi , HAYASHI Izumi , SHIMADA Jingoro , YOSHIDA Masaki , SAITO Atsushi , SHIBA Koya , KAJI Masanobu , HORI Seiji , SAKAI Osamu , YOSHIKAWA Takashi , MIYASHITA Hideo , ONO Yasuo , BABA Masumi , KOBAYASHI Hiroyuki , OSHITANI Hiroshi , MIURA Hiroshi , INOUE Takashi , SHIMADA Kaoru , GOTO Mieko , GOTO Hajime , TAKAOKA Kazuo , SANO Yasuyuki , MIYAMOTO Yasufumi , ARAI Yasuo , MATSUMURA Kanzaburo , SUZUKI Akira , NAKAMORI Yoshitaka , NARUI Koji , NOGUCHI Masayuki , NAKATANI Tatsuo , NAKATA Koichiro

    新しい注射用セフェム系抗生物質cefpirome sulfate (以下CPR) の呼吸器感染症に対する有効性と安全性を, ceftazidime (以下CAZ) を対照薬とし比較検討した. CPR0.5g×2/日, 1.0g×2/日, 及び CAZ1.0g×2/日 (以下 CPR 0.5g群, CPR 1.0g群, CAZ群) を原則として14日間投与し, 以下の成績を得た.<BR> …

    Kansenshogaku Zasshi 65(4), 400-422, 1991

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  • An Optimum Dose-Finding Study of HR810 (CPR) in Chronic Respiratory Tract Infections

    SOEJIMA Rinzo , OHMICHI Mitsuhide , WATANABE Akira , OIZUMI Kotaro , HONDA Yoshihiro , TOKUE Yutaka , MOTOMIYA Masakichi , SATO Kazuo , NAGAI Kosaku , SHIMODA Shigeru , KONNO Kiyoshi , HINO Jiro , HAYASHI Izumi , OSHITANI Hiroshi , MIURA Hiroshi , INOUE Takashi , KOBAYASHI Hiroyuki , SHIMADA Kaoru , INAMATSU Takashi , GOTO Mieko , OKA Shinichi , GOTO Hajime , SUMI Masaru , NAKAMORI Yoshitaka , NARUI Koji , NOGUCHI Masayuki , NAKAYA Tatsuo , NAKATA Koichiro , SAKURAI Iwao , IMAI Takeo , MATSUMOTO Fumio , ODAGIRI Shigeki , SUZUKI Kaneo , OKIMOTO Niro , MUROHASHI Kou , TAKAHASHI Hiroshi , ASHIKARI Yasuhiko , KOYAMA Izumi , ISHII Toshikazu , TSUBURA Eiro , NAKAGAWA Masaru , NISHIKAWA Hideki , TAKISHITA Yoshihiro , BANDO Hiroyasu , YAGI Susumu , HASHIMOTO Yoshihiro , ATAGI Shinji , MATSUMOTO Yukio , YAMAMOTO Mitsunobu , KONISHI Tatsuya , SUGIMOTO Yuji , SAKATA Takuya , HIRAI Hiroaki , HITSUDA Yutaka , SASAKI Takao , TSUKIYAMA Kuninori , HARA Kohei , HIROTA Masaki , KOHNO Shigeru , HAYASHI Toshiaki , SUYAMA Naofumi , MIYAZAKI Yukishige , DOHTSU Yasumasa , YASUOKA Akira , KATSUMATA Tatsuya , YAMADA Hiroshi , MATSUSHIMA Toshiharu , YOSHIDA Toshiaki , NAGATAKE Tsuyoshi , AKIYAMA Moritoshi , TAKASUGI Masakazu , TAGUCHI Mikio , WATANABE Kiwao , MATSUMOTO Keizo , NASU Masaru , GOTO Jun , SHIGENO Hideaki , KAWANISHI Masayoshi , GOTO Yoichiro , TASHIRO Takayoshi , NAGAI Hiroyuki , YAMAZAKI Toru , AKASHI Mitsunobu , SAITO Atsushi , FUKUHARA Hiroshi , KANESHIMA Hiroshi , IRABU Yuei , SHIMOJI Katsuyoshi , HIRAGA Yohmei , KITSUKAWA Keizo , SHIGENO Yoshiteru , OGAWA Nobuya

    呼吸器感染症に対するcefpirome sulfate (HR810, CPR) の呼吸器感染症に対する至適用量を検索する為に, 慢性気道感染症を対象として至適用量検索試験を実施し, また, 本剤の臨床的特性をceftazidime (CAZ) と比較した. 慢性気道感染症の入院患者に対しCPR 0.5g×2/日 (HR0.5g群), CPR1.0g×2/日 (HR 1.0g群) CAZ 1.0g …

    Kansenshogaku Zasshi 65(1), 96-109, 1991

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  • A Comparative Study Between Cefodizime (CDZM) and Cefotaxime (CTX) in Respiratory Tract Infections

    TAKEBE Kazuo , NAKAZONO Makoto , KAWAI Shin , SHIMADA Kaoru , SATO Yasuyuki , MIYAMOTO Yasufumi , TANIMOTO Hiroichi , YOSHIMURA Kunihiko , NAKATANI Tatsuo , CHONABAYASHI Naohiko , NAKAMORI Yoshitaka , NOGUCHI Masayuki , KAWAGISHI Takahiko , NAKATA Koichiro , YAMANE Yoshiji , UENO Katsunori , KATO Tatsuo , WATANABE Kentaro , KOYAMA Masaru , KAWAGUCHI Yoshiaki , IKEMOTO Hideo , WATANABE Kazuyoshi , KOHARA Tomoo , TAMAZAWA Naoki , INAGAKI Masayoshi , FUJIMORI Ippei , KAWABE Hiroshi , KOBAYASHI Yoshio , MATSUOKA Yasuo , OKUBO Takao , ITO Akira , FUKAYA Kazufuto , MATSUMOTO Fumio , ODAGIRI Shigeki , MIYAZAWA Tadashi , MATSUNAGA Keiichiro , SUZUKI Kaneo , MUROHASHI Kou , TAKAHASHI Kenichi , NUMATA Hiroyuki , WATANUKI Yuji , YAMAKI Izumi , ISHII Shunichi , ARAKAWA Masaaki , WADA Koichi , KIMURA Kenichi , TAKATO Masanaga , SEKINE Makoto , AOKI Nobuki , OYAMA Kaoru , OHYA Nobuo , HAYASE Mitsuru , TAKEUCHI Toshihiko , KATO Masahito , HANAKI Hidekazu , KATO Joichi , KOSAKA Shirou , YAMAMOTO Toshiyuki , SUZUKI Kanzo , ADACHI Satoru , YAMAMOTO Kazuhide , MIKI Fumio , IKUNO Yoshiyasu , INOUE Eiji , MURATA Akihito , TANIZAWA Shinichi , SAKAMOTO Kazuo , SAGARA Morio , KAWASE Yoshio , KINUGAWA Fumiaki , SOEJIMA Rinzo , NIKI Yoshito , TASAKA Yoshikazu , NAKAJIMA Masamitus , TSUKIYAMA Kuninori , UMEKI Shigenobu , HINO Jiro , WATANABE Masatoshi , OKAMOTO Katsuhiro , YAGI Susumu , KAWANE Hiroshi , SASAKI Takao , MATSUMOTO Yukio , SUGIMOTO Yuji , HITSUDA Yutaka , HIRAI Hiroaki , YAMAKIDO Michio , HASEGAWA Kenji , KAMIGAKI Ikuo , UEHARA Osamu , YOKOTA Yoshihiro , KAMITSUNA Akimitsu , KURIMURA Osamu , SASAKI Hideo , FUKUHARA Hirofumi , SAWAE Yoshiro , TAKAGI Koji , HARA Kohei , HIROTA Masaki , YAMAGUCHI Keizo , OSONOI Ken , KOHNO Sigeru , HAYASHI Toshiaki , KOGA Hironobu , SUYAMA Naofumi , DOTSU Yasumasa , MASUYAMA Yasuharu , MASHIMOTO Hideo , MASAKI Miyako , INOUE Yuichi , YASUOKA Akira , IMAMURA Kenichi , SAITOU Miyoko , SASAYAMA Kazuo , TOMONO Kazunori , KOMORI Munetaka , NAKANO Masamoto , ITO Naomi , MATSUMOTO Keizo , OISHI Kazunori , TAKAHASHI Atsushi , SHISHIDO Harumi , YAMAMOTO Masashi , HAYASHI Shigeki , ARAKI Shukuro , ANDO Masayuki , SUGA Moritaka , NASU Masaru , GOTO Yoichiro , SHIGENO Hideaki , GOTO Jun , TASHIRO Takayoshi , SHIMIZU Kihachiro , SAITO Akira , TOMIZAWA Masumi , FUJINE Masaru , SHINOHARA Masahide , SATO Mikiya , KUMANO Hiroyuki , KIMURA Osamu , MINAKAMI Hirotoshi , MASUDA Mitsuo , TAKEUCHI Keisuke , AMASAKI Yoshiharu , NAKAYAMA Ichiro , UEHARA Soichiro , HIRAYAMA Akio , HIRAGA Yohmei , OHMICHI Mitsuhide , SASAOKA Shoichi , HAYASHI Masato , HOSOYA Kenichi , MURAKAMI Seiichi , TAMURA Masao , ITO Takashi , KOKUBU Kumi , KURAMITSU Hiroshi , MORIYA Katsura , SATO Nobuhisa , TANIFUJI Kazuo , MIYA Kazumichi , KOBAYASHI Hiroshi , YOSHIDA Tsukasa , TOMIYAMA Masahiko , TAKEUCHI Kenichi , KANAYAMA Hiromi , ITO Toshiharu , TAKAHASHI Keiji , IKEDA Hideki , ITASAKA Miyoko , TAKISHIMA Tamotsu , TANNO Yasuo , NISHIOKA Kiyo , KONNO Kiyoshi , TAMURA Toyokazu , AONUMA Seiichi , TOKUE Yutaka , KITAMURA Naoto , HONDA Yoshihiro , ONO Reiko , WATANABE Akira , SASAKI Masako , OIZUMI Kotaro , SATO Kazuo , HAYASHI Izumi , ENDOU Katsumi , OHNUMA Kikuo , FUKUI Toshio , MIZUKOSHI Kazuo , OKUI Shinji , KATSU Masataka , ABE Tohru , TAKANO Makoto , HOSONO Osamu , KAWAI Takeshi , ONAKA Akio , ISHIMARU Kouhei , HIGASHI Fuyuhiko , FUNATSU Yuzo , UEDA Yasushi , SAITO Atsushi , SHIMADA Jingoro , SHIBA Kohya , MIYAHARA Tadashi , UEDA Yuichiro , ONO Yasuo , BABA Masumi , OKUSHIMA Toshimi , NISHIYA Hajime , NOZUE Norio , MURAOKA Akira , HAGA Toshiaki , MIYASHITA Hideo , UZUKA Yoshio , KOBAYASHI Hiroyuki , OSHITANI Hiroshi , INOUE Hisashi , KAWAHIRA Masahide

    新しいセフェム系抗生物質Cefodizime (CDZM) の呼吸器感染症に対する有効性と安全性を客観的に評価する目的で, Cefotaxime (CTX) を対照薬として, 比較試験 (well-controlled comparative study) を実施した.<BR>両薬剤ともに1回1gを1日2回, 点滴静注にて原則として14日間投与した.<BR>臨床効果, 細菌 …

    Kansenshogaku Zasshi 63(4), 318-351, 1989

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  • <I>IN VITRO</I> ANTIBACTERIAL ACTIVITY AND PHARMACOKINETICS OF OFLOXACIN IN CHRONIC RESPIRATORY TRACT INFECTIONS  [in Japanese]

    SUGIMOTO YUJI , MATSUMOTO YUKIO , HITSUDA YUTAKA , YAMAMOTO YOSHIMARO , ISHITOBI KAZUYUKI , SASAKI TAKAO

    慢性呼吸器感染症5例にOfioxacin (OFLX) を投与し, 血中及び喀痰中への移行濃度を測定し, 抗菌力と比較検討した。<BR>1.<I>Haemophilus influenzae</I>, <I>Klebsiella pneumoniae</I>に対するMICを上回る喀痰中濃度が連続投与中に維持されていた。<BR> …

    The Japanese Journal of Antibiotics 40(2), 325-330, 1987

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  • Clinical Evaluation of Carumonam in Chronic Respiratory Infections:Double-Blind Study Using Cefoperazone as a Positive Control

    SHIMADA Kaoru , KOROKU Tetsuji , SAWAE Yoshiro , HAYASHI Shinichiro , ASO Hiroshi , SHIGEMATSU Nobuaki , TAKII Masahide , SHIGEOKA Hidenobu , NAGANO Hitoshi , INOUE Torao , MATSUO Shinichi , KASHIDA Yuichi , HIRAGA Yohmei , SHINODA Atsushi , ISHIBASHI Tsuneo , TAKAGI Masahiro , HARA Kohei , SAITO Atsushi , YAMAGUCHI Keizo , KOHNO Shigeru , MIURA Naoki , IDE Takashi , RIKITAKE Teruhiko , KIKUCHI Kohki , MATSUMOTO Keizo , RIKITOMI Naoto , NASU Masaru , GOTO Jun , GOTO Yoichiro , TASHIRO Takayoshi , ANDO Masayuki , SUGA Moritake , YAMAMOTO Asako , ITO Susumu , KASAGI Akiji , TAMURA Masao , KONISHI Kazuki , ITO Takashi , HAYASHI Masato , KAWAKAMI Yoshikazu , KONNO Kiyoshi , OIZUMI Kotaro , AONUMA Seiichi , HAYASHI Izumi , KATSU Masataka , FUKUI Toshio , KAWAI Mieko , YOKOSE Takashi , UEDA Yasushi , SAITO Atsushi , ABE Shosaku , MIYAHARA Tadashi , IKEMOTO Hideo , WATANABE Kazuyoshi , KOBAYASHI Hiroyuki , TAKEDA Hiroaki , MASHIMO Keimei , TANIMOTO Hiroichi , CHONABAYASHI Naohiko , YOSHIMURA Kunihiko , NAKAMORI Yoshitaka , SAITO Akira , WATANABE Kentaro , KOYAMA Masaru , SANO Yasuyuki , INAMATSU Takashi , URAYAMA Kyoko , OKUBO Takao , ITO Akira , FUJIMORI Ippei , KOBAYASHI Yoshio , KITAGAWA Yasuhisa , NAKAYAMA Ichiro , ODAGIRI Shigeki , ARAKAWA Masaaki , WADA Koichi , SEKINE Osamu , AOKI Nobuki , SATAKE Tatsuo , TAKAGI Kenzo , YAMAMOTO Kenichi , TAKEUCHI Toshihiko , KATO Masahito , TOMIZAWA Masumi , HANAKI Hidekazu , KATO Joichi , YAMAMOTO Toshiyuki , SUZUKI Kanzo , SUGIMOTO Kikuo , KUZE Fumiyuki , KURASAWA Takuya , OSHIMA Shunsaku , IZUMI Takahide , NISHIMURA Koichi , SUZUKI Akira , HAYASHI Hideo , ONODERA Hideki , IKEDA Sadao , NAKAJIMA Michio , ASAMOTO Hitoshi , OKUBO Hiroshi , UEDA Yoshihiro , YONEZU Seibun , IIDA Yube , OKAMOTO Yuruko , ONODERA Tsugutami , YASUNAGA Kojiro , MIKI Fumio , NAKAJIMA Shigenori , TOHDA Aritomo , TAKAHASI Hisao , OCHI Norio , ITAKURA Norio , NARITA Nobuhiro , SAWAKI Masayoshi , MIKASA Keiichi , YASUDA Naoya , HIGASHINO Kazuya , NABESHIMA Kenji , SOEJIMA Rinzo , NIKI Yoshihito , NISHIMOTO Yukio , YAMAKIDO Michio , KAMITSUNA Akimitsu , ITASAKA Kazumasa , SASAKI Takao , MATSUMOTO Yukio

    For an objective evaluation of the clinical efficacy and safety of carumonam (CRMN) in chronic respiratory infections due to gram-negative rod bacteria, a double-blind study was conducted using cefope …

    Kansenshogaku Zasshi 61(3), 333-355, 1987

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  • SERUM LEVELS AND SPUTUM LEVELS OF CEFOTETAN USED ON RESPIRATORY TRACT INFECTIONS  [in Japanese]

    MATSUMOTO YUKIO , HITSUDA YUTAKA , SUGIMOTO YUJI , ISHIKAWA JUJIRO , SASAKI TAKAO

    慢性呼吸器感染症の起炎菌として, グラム陰性桿菌の重要なことは今日でも変らず, その対策が慢性呼吸器感染症のキーポイントとなつている。<BR>Cefbtetan (CTT) は, 山之内製薬中央研究所で開発されたCephamycin系抗生物質で従来のCephamycin系抗生物質と比べて, グラム陰性桿菌に対する抗菌スペクトルの拡大と抗菌力の強化, 又, ヒトに静注した時の血中濃度の持 …

    The Japanese Journal of Antibiotics 39(10), 2690-2694, 1986

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  • SERUM LEVELS AND SPUTUM LEVELS OF CEFMENOXIME ON RESPIRATORY TRACT INFECTIONS  [in Japanese]

    ISHIKAWA JUJIRO , NAKATANI SHIGERU , NINOMARU SHINYA , SASAKI TAKAO , KOSHOBU TOMOAKI , MATSUMOTO YUKIO

    呼吸器感染症, 特に気道内細菌性感染症を扱う場合, 抗生物質の気道内動態を知ることは重要である。今回我々は, 呼吸器感染症 (慢性細気管支炎, 慢性気管支炎, 肺気腫, 気管支拡張症, 気管支肺炎) に, 新しいセファロスポリン系抗生物質であり, β-Lactamaseに強い抵抗性を示すとされているCefmenoxime (CMX) を投与し, 血中濃度, 喀痰中濃度を測定し, CMXの体内動態を …

    The Japanese Journal of Antibiotics 38(6), 1638-1642, 1985

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