梶波 康二 KAJINAMI Kouji

ID:9000391556698

The Second Department of Internal Medicine, Kanazawa University (1999年 CiNii収録論文より)

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Articles:  1-17 of 17

  • Effects of Combined Therapy Using Two Kinds of HMG-CoA Reductase Inhibitors in Heterozygous Familial Hypercholesterolemia

    NOZUE Tsuyoshi , IZAWA Akira , KATO Fumihiko , NAGASAWA Sinya , NOJI Yoshihiro , KAWASHIRI Masa-aki , TODO Yasuhiro , NOHARA Atsushi , INAZU Akihiro , KAJINAMI Kouji , KOIZUMI Junji , MABUCHI Hiroshi

    The levels of total and LDL-cholesterol are important risk factors for coronary atherosclerosis and recent clinical trials have shown that LDL-cholesterol lowering is benefical in both the primary and …

    The Journal of Japan Atherosclerosis Society 27(1-2), 1-6, 1999

  • Effects of LDL-Apheresis on Coronary Artery Stenosis in Patients with Familial Hypercholesterolemia

    TAKEDA Mitsuaki , MICHISHITA Ichiro , UNO Yoshihide , INAZU Akihiro , FUJITA Hajime , KAJINAMI Kouji , ITO Hideaki , KAMON Nobuo , KOIZUMI Junji , 清水 賢巳 , MABUCHI Hiroshi , 元田 憲 , TAKEDA Ryouyu , TAKEGOSHI Tadami , WAKASUGI Takanobu , UEDA Kosei , MIYAMOTO Susumu , WATANABE Akira , OTA Masayuki

    One homozygous and four heterozygous patients with familial hypercholesterolemia received. LDL-apheresis treatment from 1985 to 1987. In the homozygous patient, LDL-apheresis was carried out every 3 o …

    The Journal of Japan Atherosclerosis Society 17(5), 717-724, 1989

  • LDL Receptor Gene Mutations and Coronary Atherosclerosis

    KAJINAMI Kouji

    Seventy-nine abnormal alleles of low density lipoprotein receptor (LDLR) gene in unrelated Japanese patients with familial hypercholesterolemia (FH) were screened and the following results were obtain …

    The Journal of Japan Atherosclerosis Society 16(8), 1039-1044, 1989

  • LDL Receptor Gene Mutations in Japanese Patients with Familial Hypercholesterolemia

    KAJINAMI Kouji , MABUCHI Hiroshi

    The LDL receptor gene mutations of FH patients from 190 unrelated Japanese families were screened and the following results were obtained:<br>1. Four types of new variants were identified throug …

    The Journal of Japan Atherosclerosis Society 17(5), 675-678, 1989

  • The Effects of LDL-Apheresis and Plasma Exchange on Cholesterol Level and Lipid Composition of Low and High Density Lipoproteins in Homozygous Patients with Familial Hyper-Cholesterolemia

    KOIZUMI Junji , MICHISHITA Ichiro , TAKEDA Mitsuaki , HUJITA Hajime , KAJINAMI Kouji , INAZU Akihiro , MABUCHI Hiroshi , TAKEDA Ryoyu

    The low plasma HDL concentration and cholesterol-rich LDL may play a role in the early onset of atherosclerosis in homozygous patient with familial hypercholesterolemia. We studied effects of plasma e …

    The Journal of Japan Atherosclerosis Society 16(1), 53-57, 1988

    J-STAGE 

  • A New Variant of Low Density Lipoprotein Receptor Gene and its Application to Neonatal Diagnosis of Familial Hypercholesterolemia

    KAJINAMI Kouji , ITO Hideaki , TAKEDA Mitsuaki , MICHISHITA Ichiro , WAKASUGI Takanobu , KOIZUMI Junji , MABUCHI Hiroshi , TAKEDA Ryoyu

    We screened abnormal alleles of the low density lipoprotein receptor (LDLR) gene in 35 unrelated Japanese patients with heterozygous familial hypercholesterolemia (FH), and obtained the results as fol …

    The Journal of Japan Atherosclerosis Society 15(8), 1675-1678, 1988

    J-STAGE 

  • The Effects of LDL-Apheresis and Plasma Exchange on Cholesterol Level and Lipid Composition of Low and High Density Lipoproteins in Homozygous Patients with Familial Hyper-Cholesterolemia

    KOIZUMI Junji , MICHISHITA Ichiro , TAKEDA Mitsuaki , HUJITA Hajime , KAJINAMI Kouji , INAZU Akihiro , MABUCHI Hiroshi , TAKEDA Ryoyu

    The low plasma HDL concentration and cholesterol-rich LDL may play a role in the early onset of atherosclerosis in homozygous patient with familial hypercholesterolemia. We studied effects of plasma e …

    The Journal of Japan Atherosclerosis Society 16(1), 53-57, 1988

  • A New Variant of Low Density Lipoprotein Receptor Gene and its Application to Neonatal Diagnosis of Familial Hypercholesterolemia

    KAJINAMI Kouji , ITO Hideaki , TAKEDA Mitsuaki , MICHISHITA Ichiro , WAKASUGI Takanobu , KOIZUMI Junji , MABUCHI Hiroshi , TAKEDA Ryoyu

    We screened abnormal alleles of the low density lipoprotein receptor (LDLR) gene in 35 unrelated Japanese patients with heterozygous familial hypercholesterolemia (FH), and obtained the results as fol …

    The Journal of Japan Atherosclerosis Society 15(8), 1675-1678, 1988

  • Apolipoprotein A-I Gene Polymorphism in Patients with Coronary Heart Disease and Normolipidemic Controls

    ITO Hideaki , KOIZUMI Junji , MABUCHI Hiroshi , TAKEDA Ryoyu , INAZU Akihiro , MATSUSHITA Hiroyuki , FUJITA Hajime , KAJINAMI Kouji , TAKEDA Mitsuaki , MICHISHITA Ichiro , KAMON Nobuo , WAKASUGI Takanobu

    A low level of high-density-lipoprotein (HDL) has been reported to be a predictive indicator of coronary heart disease (CHD). Apolipoprotein A-I is a principal protein constituent of HDL and decreased …

    The Journal of Japan Atherosclerosis Society 15(7), 1521-1525, 1987

    J-STAGE 

  • DNA Polymorphism in the Low Density Lipoprotein Receptor Gene

    KAJINAMI Kouji , ITO Hideaki , TAKEDA Mitsuaki , FUJITA Hajime , MICHISHITA Ichiro , WAKASUGI Takanobu , MABUCHI Hiroshi , TAKEDA Ryoyu

    Abnormal low density lipoprotein receptor (LDL-R) causes familial hypercholesterolemia (FH).<br>Some abnormalities of the LDL-R gene were revealed in FH patients, and common polymorphism in the …

    The Journal of Japan Atherosclerosis Society 15(4), 919-923, 1987

    J-STAGE 

  • DNA Polymorphism in the Low Density Lipoprotein Receptor Gene

    KAJINAMI Kouji , ITO Hideaki , TAKEDA Mitsuaki , FUJITA Hajime , MICHISHITA Ichiro , WAKASUGI Takanobu , MABUCHI Hiroshi , TAKEDA Ryoyu

    Abnormal low density lipoprotein receptor (LDL-R) causes familial hypercholesterolemia (FH).<br>Some abnormalities of the LDL-R gene were revealed in FH patients, and common polymorphism in the …

    The Journal of Japan Atherosclerosis Society 15(4), 919-923, 1987

  • Apolipoprotein A-I Gene Polymorphism in Patients with Coronary Heart Disease and Normolipidemic Controls

    ITO Hideaki , INAZU Akihiro , MATSUSHITA Hiroyuki , FUJITA Hajime , KAJINAMI Kouji , TAKEDA Mitsuaki , MICHISHITA Ichiro , KAMON Nobuo , WAKASUGI Takanobu , KOIZUMI Junji , MABUCHI Hiroshi , TAKEDA Ryoyu

    A low level of high-density-lipoprotein (HDL) has been reported to be a predictive indicator of coronary heart disease (CHD). Apolipoprotein A-I is a principal protein constituent of HDL and decreased …

    The Journal of Japan Atherosclerosis Society 15(7), 1521-1525, 1987

  • Studies of pLDLR-1: A Partial cDNA Clone for the Bovine Adrenal Low Density Lipoprotein Receptor

    KAJINAMI Kouji , TAKEDA Ryoyu , TAKEDA Mitsuaki , ITO Hideaki , SAKAI Yasuyuki , MICHISHITA Ichiro , KAMON Nobuo , SAKAI Takeshi , WAKASUGI Takanobu , MABUCHI Hiroshi

    pLDLR-1 is a cDNA clone for the LDL receptor. This clone was obtained from a bovine adrenal cDNA library that was constructed by Okayama-Berg method and corresponds to approximately half of the mRNA f …

    The Journal of Japan Atherosclerosis Society 13(6), 1353-1356, 1986

    J-STAGE 

  • Studies of Human Low Density Lipoprotein Receptor Gene

    KAJINAMI Kouji , TAKEDA Mitsuaki , ITO Hideaki , MICHISHITA Ichiro , KAMON Nobuo , SAKAI Yasuyuki , WAKASUGI Takanobu , MABUCHI Hiroshi , TAKEDA Ryoyu

    Familial hypercholesterolemia (FH) is an autosomal dominant disease due to abnormality of the low density lipoprotein receptor (LDL-R), and is characterized by hypercholesterolemia and premature coron …

    The Journal of Japan Atherosclerosis Society 14(3), 485-489, 1986

    J-STAGE 

  • Studies of pLDLR-1: A Partial cDNA Clone for the Bovine Adrenal Low Density Lipoprotein Receptor

    KAJINAMI Kouji , TAKEDA Mitsuaki , ITO Hideaki , SAKAI Yasuyuki , MICHISHITA Ichiro , KAMON Nobuo , SAKAI Takeshi , WAKASUGI Takanobu , MABUCHI Hiroshi , TAKEDA Ryoyu

    pLDLR-1 is a cDNA clone for the LDL receptor. This clone was obtained from a bovine adrenal cDNA library that was constructed by Okayama-Berg method and corresponds to approximately half of the mRNA f …

    The Journal of Japan Atherosclerosis Society 13(6), 1353-1356, 1986

    J-STAGE 

  • Studies of Human Low Density Lipoprotein Receptor Gene

    KAJINAMI Kouji , TAKEDA Mitsuaki , ITO Hideaki , MICHISHITA Ichiro , KAMON Nobuo , SAKAI Yasuyuki , WAKASUGI Takanobu , MABUCHI Hiroshi , TAKEDA Ryoyu

    Familial hypercholesterolemia (FH) is an autosomal dominant disease due to abnormality of the low density lipoprotein receptor (LDL-R), and is characterized by hypercholesterolemia and premature coron …

    The Journal of Japan Atherosclerosis Society 14(3), 485-489, 1986

    J-STAGE 

  • cDNA Cloning of Human Apo-E and Analysis of the Apo-E Gene in a Patient with Apo-E Absence

    TAKEDA Mitsuaki , KAJINAMI Kouji , ITO Hideaki , SAKAI Kenji , MICHISHITA Ichiro , KAMON Nobuo , YOSHIMURA Akira , WAKASUGI Takanobu , MABUCHI Hiroshi , TAKEDA Ryoyu

    Recombinant clones containing cDNA sequences coding for human Apo-E have been isolated from a human adult liver cDNA library. The library was constructed by the Okayama-Berg method and screened with t …

    The Journal of Japan Atherosclerosis Society 13(4), 843-847, 1985

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