Kasuga Masato

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  • PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

    Matsumoto Michihiro , Ogawa Wataru , Akimoto Kazunori , Inoue Hiroshi , Miyake Kazuaki , Furukawa Kensuke , Hayashi Yoshitake , Iguchi Haruhisa , Matsuki Yasushi , Hiramatsu Ryuji , Shimano Hitoshi , Yamada Nobuhiro , Ohno Shigeo , Kasuga Masato , Noda Tetsuo , 島野 仁 , 山田 信博

    PKCλ is implicated as a downstream effector of PI3K in insulin action. We show here that mice that lack PKCλ specifically in the liver (L-λKO mice), produced with the use of the Cre-loxP system, exhib …

    The journal of clinical investigation 112(6), 935-944, 2003-09

    IR 

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