検索結果 33 件

堀 泰典, 須賀 川圭子, 落合 英彦, 中井 康光 昭和医学会雑誌 57 (1), 56-63, 1997

ラット視床下部・下垂体系におけるグルタミン酸含有ニューロンの分布と微細構造を免疫電顕的に観察し, さらにグルタミン酸含有ニューロンとソマトスタチン含有ニューロン間のシナプス相関について, 二重免疫電顕的に観察した.グルタミン酸様免疫陽性ニューロンは, 視床下部の室周囲核および弓状核に多数分布していた.これらグルタミン酸様免疫陽性ニューロンには免疫陰性で性質不明のニューロンから多数のシナプス入力を…

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池田 直也, 藤木 薫, 二宮 半三, 後藤 俊文, 藤木 芳成, 金久 純也, 堀 泰典, 竹内 宏, 村田 晴彦 歯科放射線 30 (1), 23-28, 1990

Keratoakanthoma is a benign lesion of epithelial hyperplasia originating from the surface epithelium. This lesion is frequently mistaken for squamous-cell carcinoma because of its similar clinical …

DOI 医中誌

玉木 直子, 于 世鳳, 上田 裕康, 田島 一範, 堀 泰典, 金久 純也, 竹内 宏, 佐藤 勝, 藤井 輝久 日本歯周病学会会誌 26 (4), 696-700, 1984

It is well known that the fibronectin shows affinity to various components of biological and nonbiological substances. Thus, fibronectin which exists in salivary flow, may produce acquired pellicle, …

DOI PubMed 医中誌

田島 一範, 于 世鳳, 玉木 直子, 上田 裕康, 堀 泰典, 金久 純也, 竹内 宏, 村上 純一, 白木 雅文, 河内 準治, 岩山 幸雄 日本歯周病学会会誌 26 (4), 701-709, 1984

This study was attempted in order to clalify a distribution of fibronectin in supragingival and sub-gingival calculus by using immunohistological technique.<br>The component of fibronectin was …

DOI PubMed 医中誌

竹内 宏, 堀 泰典, 于 世鳳, 金久 純也, 阿部 公生, 佐藤 勝, 兼松 宣武, 藤井 輝久 日本歯周病学会会誌 26 (1), 83-87, 1984

Fibronectin has a nature which combins with various components of biological and nonbiological substances by its specific molecular formula. On the assumption that fibronectin which has such …

DOI PubMed 医中誌

竹内 宏, 于 世鳳, 堀 泰典, 金久 純也, 藤井 輝久, 佐藤 勝, 並河 勇, 巽 幹雄, 高木 順彦 日本歯周病学会会誌 26 (2), 257-261, 1984

The fibronectin in acquired pellicle on the surface of tooth enamel was demonstrated by a fluorescence antibody technique (FITC-labeled anti goat serum to human plasma fibronectin, Sera Lab.). The …

DOI PubMed 医中誌

金久 純也, 干世 鳳, 堀 泰典, 竹内 宏 歯科基礎医学会雑誌 26 (4), 1046-1053, 1984

The expression of the murine leukemia virus (MuLV) antigen was demonstrated in the parotid and submandibular salivary glands and exorbital lacrimal glands of NZB mice by using the indirect …

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于 世鳳, 堀 泰典, 金久 純也, 竹内 宏, 佐藤 勝, 並河 勇 歯科基礎医学会雑誌 26 (2), 326-331, 1984

The purpose of this investigation was to study the localization of bacterial chondroitinase ABC in the human gingival tissue with periodontal disease and influence of the periodontal tissue due to …

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藤木 薫, 黒川 貞幸, 池田 直也, 二宮 半三, 後藤 俊文, 金久 純也, 堀 泰典, 竹内 宏 歯科放射線 24 (2), 132-137, 1984

Adenoid cystic carcinoma is a malignant salivaly gland tumor that occurs most commonly in the hard palate.<br>A case of adenoid cystic carcinoma in an 85-year-old male is presented with special …

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堀 泰典, 竹内 宏, 佐藤 勝, 並河 勇 日本歯周病学会会誌 25 (1), 195-199, 1983

We reported thet oral bacteria in dental plaque were arrested to penetrate into periodontal tissue by secretory IgA coating to the bacteria.<br>In this study, the presence and degree of non-specific …

DOI PubMed 医中誌

竹内 宏, 堀 泰典, 佐藤 勝, 並河 勇 歯科基礎医学会雑誌 25 (2), 443-447, 1983

The purpose of the present investigation was to detect bacterial chondroitinase and hyaluronidase in bacteria of 15 species as shown in Table 1.<BR>Smear specimens obtained from their pure culturing …

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竹内 宏, 堀 泰典, 金久 純他, 谷 明, 橋本 政明, 佐川 寛典 歯科基礎医学会雑誌 25 (1), 31-36, 1983

Existence of Actinomyces products in inflamed human gingiva has been well known but the effects on periodontal tissue were yet to be clarified fully.<BR>In this study, the effects of tissue injuries …

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兼松 宣武, 竹内 宏, 堀 泰典, 谷 明, 元島 泉, 佐川 寛典 歯科基礎医学会雑誌 25 (1), 91-94, 1983

The purpose of this investigation has been to demonstrate the presence of direct tissue damage agents in extract of Actinomyces viscosus and A. naeslundii to cultured cell. L-cells were cultured in …

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竹内 宏, 堀 泰典, 金久 純也, 上田 雅俊, 谷 明, 佐川 寛典 歯科基礎医学会雑誌 25 (2), 437-442, 1983

The purpose of this investigation was to study the presence of bacteria chondroitinase ABC and basterial hyaluronidase in inflamed human gingiva by a fluorescence antibody technique. The presence of …

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竹内 宏, 堀 泰典, 金久 純也 歯科基礎医学会雑誌 25 (1), 130-135, 1983

Immunopathological study of the salivary and lacrymal glands of SD-rats which inoculated with DNA antigen once a week over a period of ten months was attempted. Histopathological observation …

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竹内 宏, 堀 泰典, 佐藤 勝, 並河 勇 日本歯周病学会会誌 24 (4), 580-583, 1982

We reported that bacteria in dental plaque were arrested to penetrate into periodontal tissue by secretory IgA coating to the bacteria. It was clarified wheather some bacteria were coated by …

DOI PubMed 医中誌

竹内 宏, 堀 泰典, 兼松 宣武, 阿部 公生 日本歯周病学会会誌 24 (4), 584-588, 1982

It is well known that the fibronctin composed of cell surface and plasma fibronectin plays a role of promoting cell proliferation and then regeneration of injured tissue by its biological function. …

DOI PubMed 医中誌

竹内 宏, 金久 純也, 堀 泰典, 上田 雅俊, 今津 智子, 今井 久夫, 谷 明, 倉松 常俊, 佐川 寛典 日本歯周病学会会誌 24 (3), 421-426, 1982

The localization of fibronectin in the human inflamed gingiva was demonstrated by a immunofluorescent technique which used monoclonal antibody by product of a hybridoma formed by the PEG fusion of …

DOI PubMed 医中誌

竹内 宏, 堀 泰典, 金久 純也, 佐藤 勝, 並河 勇 歯科基礎医学会雑誌 24 (4), 986-992, 1982

Existence of bacterial enzymes (chondroitinase ABC and hyaluronidase) in the dental plaque obtained from 50 volunteers (22 years old) and clinical health demonstrated by fluorescence antibody …

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金久 純也, 堀 泰典, 竹内 宏, 谷 明, 佐川 寛典 歯科基礎医学会雑誌 24 (3), 738-745, 1982

Endotoxin has been considered as playing an important role in bone resorption of periodontitis. Many <I>in vitro</I> studies show evidences to strengthen this concept. The aim of this study is to …

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竹内 宏, 金久 純也, 堀 泰典 歯科基礎医学会雑誌 24 (3), 727-732, 1982

Immunopathological studies of salivary glands and lacrymal glands which, through repeated injection of DNA antigens, suffered from injury with the infiltration and proliferation of lymphocytes …

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竹内 宏, 金久 純也, 堀 泰典 歯科基礎医学会雑誌 24 (3), 733-737, 1982

The anti DNA serum is a kind of autoantibody which sometimes brings about various autoimmune diseases. The mechanism of tissue injuries caused by and DNA serum are not well known. It is however …

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竹内 宏, 金久 純也, 堀 泰典, 上田 雅俊, 今井 久夫, 谷 明, 佐川 寛典 日本歯周病学会会誌 24 (1), 114-120, 1982

Rat lymphocytes sensitized with <i>Actinomyces naeslundii</i> ATCC 12104 strain and <i>Actinomyces viscosus</i> ATCC 19246 strain showed positive fluorescence from one week to four weeks after …

DOI PubMed 医中誌

堀 泰典, 金久 純也, 竹内 宏, 上田 雅俊, 大塚 健司, 信藤 孝博, 倉松 常倍, 谷 明, 佐川 寛典 日本歯周病学会会誌 24 (4), 575-579, 1982

Discrepancy in quantity of secretory IgA between buccal and lingual dental plaque was clarified by immunopathological study.<br>Extensive fuorescence which showed existence of secretory IgA was …

DOI PubMed 医中誌

堀 泰典, 金久 純也, 竹内 宏, 上田 雅俊, 橋本 光示, 今井 久夫, 佐波 義連, 谷 明, 佐川 寛典 日本歯周病学会会誌 24 (4), 571-574, 1982

The object of present investigation was to demonstrate the levels of secretory IgA in the human dental plaque scraped from buccal sulcus.<br>The dental plaques which were obstained from 50 …

DOI PubMed 医中誌

竹内 宏, 金久 純也, 堀 泰典, 上田 雅俊, 小早川 博昭, 木村 雅年, 橋本 政明, 谷 明, 佐川 寛典 日本歯周病学会会誌 24 (3), 416-420, 1982

Secretory IgA and serum IgA in human inflammatory gingiva were demonstrated by immunopathological observation. Secretory IgA localized in the dental plaque, on the surface of gingiva, in the …

DOI PubMed 医中誌

竹内 宏, 金久 純也, 堀 泰典, 上田 雅俊, 河野 忠雄, 谷 明, 佐川 寛典 歯科基礎医学会雑誌 24 (3), 746-751, 1982

To detect the subpopulation or subset of immunecompetent cells which specifically react with oral bacterial antigens, it is most significant to clarify the correlation of immune reaction to …

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竹内 宏, 金久 純也, 堀 泰典 歯科基礎医学会雑誌 23 (3), 451-463, 1981

Repeated injections of DNA antigen gave rise to acinous cell injuries and T-cell infiltration with proliferation of the rat parotid glands and internal lacrymal glands following the formation of …

DOI 医中誌

竹内 宏, 金久 純也, 堀 泰典, 谷 明, 佐川 寛典 歯科基礎医学会雑誌 23 (4), 739-744, 1981

By use of immunofluorescent technique, we found Actinomyces naeslundii in the intra-and intercellular spaces of the sulcular epithelium and in the subepithelial connective tissue of the gingiva of …

DOI 医中誌

竹内 宏, 金久 純也, 堀 泰典, 谷 明, 佐川 寛典 歯科基礎医学会雑誌 23 (4), 745-749, 1981

By use of indirect Immunofluorescent technique, immunocytes which reacted with thesoluble antigen of <I>Actnomyces naeslundii</I> were demonstrated in 23 gingivae of 24 individuals with periodontal …

DOI 医中誌

竹内 宏, 金久 純也, 堀 泰典, 上田 雅俊, 今井 久夫 日本歯周病学会会誌 23 (4), 610-615, 1981

This study was made to clarify the existense of antibiotic factors to oral bacteria in the gingival pocket fluid of individuals with periodontal disease by using fluorescent antibody techniques. …

DOI PubMed 医中誌

金久 純也, 堀 泰典, 竹内 宏, 谷 明, 佐川 寛典 歯科基礎医学会雑誌 23 (3), 464-472, 1981

This study was made to clarify the localization of Fusobacterium endotoxin in the human ginigival tissue with periodontal disease by utilizing FITC-labeled anti-endotoxin sera; the antisera were …

DOI 医中誌

竹内 宏, 金久 純也, 松田 信介, 堀 泰典 歯科基礎医学会雑誌 22 (4), 594-605, 1980

口腔内細菌によって感作されたT-cellが再度対応抗原と遭遇した際に, 歯周組織が如何なる影響を蒙むるかを免疫病理学的に検討した。その結果, 今回の実験の如くnon-specific mitogenのCon AとPHAにほぼ同等の芽球化率を示すようなT-cellのsubsetは組織傷害性に作用することなく, むしろ傷害に対して防御的に作用することが分った。一方, …

DOI 医中誌