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Tomoko Nakatsuka, Hideyuki Aoki, Mikiko Kida, Akimitsu Kugimiya Bioscience, Biotechnology, and Biochemistry 83 (9), 1616-1623, 2019-09-02

...> <jats:p>Abbreviations: L-His: L-histidine; L-Tyr: L-tyrosine; aaRSs: aminoacyl-tRNA synthetases; ATP: adenosine-5′-triphosphate; aminoacyl-AMP-aaRS: aminoacyl-adenylate intermediate; Ap4A...

DOI PDF 被引用文献3件

María J. Pérez de Lara, Ana Guzmán-Aranguez, Rosa Gómez-Villafuertes, Javier Gualix, María Teresa Miras-Portugal, Jesús Pintor Purinergic Signalling 14 (3), 259-270, 2018-06-08

DOI PDF Web Site 被引用文献1件

Darius Ebrahimi‐Fakhari, Chi Cheng, Kira Dies, Amelia Diplock, Danielle B. Pier, Conor S. Ryan, Brendan C. Lanpher, Jennifer Hirst, Wendy K. Chung, Mustafa Sahin, Elisabeth Rosser, Basil Darras, James T. Bennett American Journal of Medical Genetics Part A 176 (2), 311-318, 2017-11-28

...AP4B1 is a subunit of the adapter protein complex 4 (AP‐4), a heterotetrameric protein complex that regulates the transport of membrane proteins....

DOI Web Site Web Site ほか1件 被引用文献1件

Yoshio Kimura, Chihiro Tanaka, Katsuho Sasaki, Masashi Sasaki Microbiology 163 (1), 86-93, 2017-01-01

DOI Web Site 被引用文献4件 参考文献30件

Andres M Lebensohn, Ramin Dubey, Leif R Neitzel, Ofelia Tacchelly-Benites, Eungi Yang, Caleb D Marceau, Eric M Davis, Bhaven B Patel, Zahra Bahrami-Nejad, Kyle J Travaglini, Yashi Ahmed, Ethan Lee, Jan E Carette, Rajat Rohatgi eLife 5 e21459-, 2016-12-20

...These include a requirement for the transcription factor AP-4, a role for the DAX domain of AXIN2 in controlling β-catenin transcriptional activity, a contribution of glycophosphatidylinositol anchor biosynthesis...

DOI PDF Web Site ほか1件 被引用文献1件

Sayuri Tanaka, Makoto Kihara, Manabu Sugimoto Bioscience, Biotechnology, and Biochemistry 79 (3), 394-401, 2015-03-04

...HvNUDX12 gene, belonging to diadenosine tetraphosphates (Ap4A) pyrophosphohydrolase subfamily gene and up-regulated by UV-C, was expressed in Escherichia coli cells....

DOI PDF 被引用文献2件

Shigetarou Mori, Hyun Kim, Emiko Rimbara, Yoshichika Arakawa, Keigo Shibayama Bioscience, Biotechnology, and Biochemistry 79 (2), 236-238, 2015-02-01

...<jats:title>Abstract</jats:title> <jats:p>Diadenosine 5′,5′′′-P1,P4-tetraphosphate (Ap4A) phosphorylase from Mycobacterium tuberculosis H37Rv (MtAPA) belongs to the histidine triad motif...

DOI PDF 被引用文献1件 参考文献13件

Wen-Tao Hou, Wen-Zhe Li, Yuxing Chen, Yong-Liang Jiang, Cong-Zhao Zhou Journal of Molecular Biology 425 (15), 2687-2698, 2013-08

DOI Web Site Web Site 被引用文献1件

Ronald A. Albright, William C. Chang, Donna Robert, Deborah L. Ornstein, Wenxiang Cao, Lynn Liu, Meredith E. Redick, J. Isaac Young, Enrique M. De La Cruz, Demetrios T. Braddock Blood 120 (22), 4432-4440, 2012-11-22

...We demonstrate that NPP4 is present on the surface of vascular endothelium, where it hydrolyzes Ap3A into AMP and ADP, and Ap4A into AMP and ATP....

DOI PDF 被引用文献3件

Agnieszka Krakowiak, Róża Pęcherzewska, Renata Kaczmarek, Agnieszka Tomaszewska, Barbara Nawrot, Wojciech J. Stec Bioorganic & Medicinal Chemistry 19 (16), 5053-5060, 2011-08

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Marta Castany, Isabel Jordi, Jaume Catala, Arcadi Gual, Miguel Morales, Xavier Gasull, Jesus Pintor Experimental Eye Research 92 (3), 221-226, 2011-03

DOI Web Site Web Site 被引用文献1件

Kimako Oka, Takashi Suzuki, Yoshiaki Onodera, Yasuhiro Miki, Kiyoshi Takagi, Shuji Nagasaki, Jun‐Ichi Akahira, Takanori Ishida, Mika Watanabe, Hisashi Hirakawa, Noriaki Ohuchi, Hironobu Sasano International Journal of Cancer 128 (8), 1770-1782, 2011-02-22

...<jats:title>Abstract</jats:title><jats:p>Nudix‐type motif 2 (NUDT2) hydrolyzes diadenosine 5′,5′′′‐p1,p4‐tetraphosphate (Ap4A) associated with various cellular functions....

DOI Web Site Web Site 被引用文献6件 参考文献33件

Russell D. Monds, Peter D. Newell, Jeffrey C. Wagner, Julia A. Schwartzman, Wenyun Lu, Joshua D. Rabinowitz, George A. O'Toole Journal of Bacteriology 192 (12), 3011-3023, 2010-06-15

...In addition, we characterized a Pho-independent role for Ap4A metabolism in regulation of biofilm formation....

DOI Web Site 被引用文献7件

Masuoka Takayoshi, Mikami Azusa, Kamei Chiaki Journal of Pharmacological Sciences 113 (1), 41-47, 2010

...mGlu-receptor agonist; however, intrahippocampal injection of (2<I>R</I>,4<I>R</I>)-4-aminopyrrolidine-2,4-dicarboxylate (APDC), a group II mGlu-receptor agonist, and L-(+)-2-amino-4-phosphonobutyric acid (L-AP4...

DOI Web Site 医中誌 参考文献46件

Rey-Ting Guo, Yeeting E. Chong, Min Guo, Xiang-Lei Yang Journal of Biological Chemistry 284 (42), 28968-28976, 2009-10

DOI Web Site Web Site ほか1件 被引用文献2件

Dao-Qi Zhang, Kwoon Y. Wong, Patricia J. Sollars, David M. Berson, Gary E. Pickard, Douglas G. McMahon Proceedings of the National Academy of Sciences 105 (37), 14181-14186, 2008-09-16

...responses were driven by cationic currents and persisted <jats:italic>in vitro</jats:italic> and <jats:italic>in vivo</jats:italic> in the presence of L-AP4...

DOI Web Site 被引用文献3件

田丸 文信, 金子 優子, 渡辺 修一 日本生理学会大会発表要旨集 2007 (0), 011-011, 2007

...We found that the spike frequency increased in proportion to the concentration of puffer-applied glutamate to the arboreal dendrite and was suppressed by the puffer-applied L-AP-4, a glutamate analogue...

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BANG V. BUI, BRAD FORTUNE Visual Neuroscience 23 (2), 155-167, 2006-03

...The cone a-wave was isolated using PDA/L-AP4 or CNQX/L-AP4....

DOI Web Site 被引用文献1件

Yu-Nee Lee, Hovav Nechushtan, Navah Figov, Ehud Razin Immunity 20 (2), 145-151, 2004-02

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Andrzej Guranowski Acta Biochimica Polonica 50 (4), 947-972, 2003-12-31

...Certain Ap4A analogs were alternative substrates of Ap4A-degrading enzymes and/or acted as enzyme inhibitors, some other helped to establish enzyme mechanisms, increased the sensitivity of certain enzyme...

DOI Web Site 被引用文献1件

Adam IWANICKI, Anna HERMAN-ANTOSIEWICZ, Marcin PIERECHOD, Simone J. SÉROR, Michał OBUCHOWSKI Biochemical Journal 366 (3), 929-936, 2002-09-15

...This enzyme shares homology with other PPP phosphatases as well as with symmetrical diadenosine tetraphosphatases related to ApaH (symmetrical Ap4A hydrolase) from Escherichia coli....

DOI PDF 被引用文献1件

Stephen W. INGRAM, Larry D. BARNES Biochemical Journal 350 (3), 663-669, 2000-09-08

...Disruption of aph1 resulted in an 85% decrease in Ap4A hydrolase activity and a 290-fold increase in the intracellular Ap4A concentration....

DOI PDF 被引用文献1件

Esteban C. Dell'Angelica, Chris Mullins, Juan S. Bonifacino Journal of Biological Chemistry 274 (11), 7278-7285, 1999-03

DOI Web Site Web Site ほか1件 被引用文献2件

M. G. Rae, E. G. Rowan, C. Kennedy British Journal of Pharmacology 124 (1), 176-180, 1998-05

...The rank order of agonist potency was ATP>AP5A∼amp;AP4A>β,γ‐me‐<jats:sc>D</jats:sc>‐ATP>UTP>>β,γ‐methylene‐<jats:sc>L</jats:sc>‐ATP....

DOI Web Site Web Site 被引用文献1件

Akiko Nishimura Trends in Biochemical Sciences 23 (5), 157-159, 1998-05

DOI Web Site Web Site 被引用文献1件

Ludwig MISSIAEN, Jan B. PARYS, Humbert DE SMEDT, Ilse SIENAERT, Henk SIPMA, Sara VANLINGEN, Karlien MAES, Rik CASTEELS Biochemical Journal 325 (3), 661-666, 1997-08-01

...Ap4A and Ap5A also interacted with a lower EC50 than ATP....

DOI PDF 被引用文献2件

A. Bigiani, R. J. Delay, N. Chaudhari, S. C. Kinnamon, S. D. Roper Journal of Neurophysiology 77 (6), 3048-3059, 1997-06-01

...glutamate responses were voltage dependent and Na<jats:sup>+</jats:sup> dependent, and appeared to be generated by nonspecific cation channels activated by glutamate. l(+)-2-amino-4-phosphonobutyric acid (l-AP4...

DOI Web Site 被引用文献1件

Alexander G. McLENNAN, Elaine MAYERS, David G. ADAMS Biochemical Journal 320 (3), 795-800, 1996-12-15

...A search of the GenBank non-redundant database revealed a putative Ap4A phosphorylase gene in the cyanobacterium Synechocystis sp....

DOI PDF 被引用文献1件

笹沼, 明美, 小林, 恭子, 倉富, 一興 東京医科大学雑誌 54 (5), 557-, 1996-09-01

機関リポジトリ 医中誌

Nirupa Chaudhari, Hui Yang, Cynthia Lamp, Eugene Delay, Claire Cartford, Trang Than, Stephen Roper The Journal of Neuroscience 16 (12), 3817-3826, 1996-06-15

...Finally, behavioral studies have indicated that MSG and<jats:sc>l</jats:sc>-2-amino-4-phosphonobutyrate (<jats:sc>l</jats:sc>-AP4), a ligand for mGluR4, elicit similar tastes in rats....

DOI Web Site 被引用文献21件

Y Huang, P N Garrison, L D Barnes Biochemical Journal 312 (3), 925-932, 1995-12-15

...<jats:p>Diadenosine 5′,5‴-P1,P4-tetraphosphate (Ap4A) asymmetric hydrolase (EC 3.6.1.17) is a specific catabolic enzyme of Ap4A found in Schizosaccharomyces pombe....

DOI PDF 被引用文献3件

笹沼, 明美, 小林, 恭子, 倉富, 一興, Sasanuma, Akemi, Kobayashi, Yasuko, Kuratomi, Kazuoki 東京医科大学雑誌 53 (5), 607-615, 1995-09-01

機関リポジトリ 医中誌 参考文献25件

笹沼, 明美, 小林, 恭子, 倉富, 一興, 久嶋, 道広 東京医科大学雑誌 53 (5), 732-, 1995-09-01

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Mayur D. Baxi, Jamboor K. Vishwanatha Biochemistry 34 (30), 9700-9707, 1995-08-01

DOI Web Site 被引用文献3件

Hassan Belrhali, Anya Yaremchuk, Michael Tukalo, Carmen Berthet-Colominas, Bjarne Rasmussen, Peter Bösecke, Olivier Diat, Stephen Cusack Structure 3 (4), 341-352, 1995-04

DOI Web Site Web Site 被引用文献2件

V Ralevic, C H Hoyle, G Burnstock The Journal of Physiology 483 (3), 703-713, 1995-03-15

...The nucleotides AP4A, AP5A, AP6A and alpha,beta‐meATP had no vasodilator effects. 6....

DOI Web Site Web Site 被引用文献1件

木村 聰城郎, 畑野 徳久, 和田 昌子, 岩田 建, 黒崎 勇二, 中山 太二, 山浦 哲明, 中島 宏 Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 18 (11), 1556-1559, 1995

...The disposition of diadenosine 5', 5'''-P<SUP>1</SUP>, P<SUP>4</SUP>-tetraphosphate (Ap4A), an endogenous dinucleotide, was investigated in rats....

DOI Web Site PubMed 被引用文献1件 参考文献11件

岩田 建, 中島 宏, 木村 聰城郎 Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 18 (5), 788-790, 1995

...Diadenosine 5', 5'''-p<SUP>1</SUP>, p<SUP>4</SUP>-tetraphosphate (Ap4A) degradation in dog plasma was inhibited by the addition of EDTA....

DOI Web Site PubMed 被引用文献2件 参考文献21件

Wietse Mulder, Inge H.J.M. Scholten, Henny van Roon, Leslie A. Grivell Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1219 (3), 719-723, 1994-11

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Xuenong Bo, Bilha Fischer, Michel Maillard, Kenneth A. Jacobson, Geoffrey Burnstock British Journal of Pharmacology 112 (4), 1151-1159, 1994-08

...The rank order of potency was Ap6A > Ap5A > Ap4A >> Ap3A >> Ap2A....

DOI Web Site Web Site 被引用文献1件

A G McLennan, E Mayers, S Hankin, N M H Thorne, M Prescott, R Powls Biochemical Journal 300 (1), 183-189, 1994-05-15

...The enzyme also catalyses Ap4A synthesis (Keq. = [Ap4A] [Pi]/[ATP][ADP] = 9 x 10(-4)) and ADP arsenolysis....

DOI PDF 被引用文献2件

吉川,源一, 川瀬,至道, 山元,英樹, 鈍宝,宗彦, 岳田,健治, 中島,宏 日本生物工学会大会講演要旨集 平成5年度 32-, 1993-11-10

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笹沼, 明美, 小林, 恭子, 倉富, 一興, Sasanuma, Akemi, Kobayashi, Yasuko, Kuratomi, Kazuoki 東京医科大学雑誌 51 (5), 469-480, 1993-09-01

機関リポジトリ 医中誌

笹沼, 明美, 小林, 恭子, 倉富, 一興 東京医科大学雑誌 51 (5), 513-, 1993-09-01

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笹沼, 明美, 小林, 恭子, 倉富, 一興 東京医科大学雑誌 50 (5), 877-, 1992-09-01

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笹沼, 明美, 小林, 恭子, 倉富, 一興 東京医科大学雑誌 49 (5), 762-, 1991-09-01

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Z Pálfi, G Surányi, G Borbély Biochemical Journal 276 (2), 487-491, 1991-06-01

...., strain PCC 6301, under both light and dark conditions led to the accumulation of bis(5′-nucleosidyl)oligophosphates: Ap4A, Ap4G, Ap3A, Ap3G and Ap3Gp2....

DOI PDF 被引用文献2件

P Plateau, M Fromant, J M Schmitter, S Blanquet Journal of Bacteriology 172 (12), 6892-6899, 1990-12

...They can also produce Ap4A at the expense of ATP and ADP. The gene (APA2) encoding Ap4A phosphorylase II was isolated and sequenced....

DOI Web Site 被引用文献3件

P Plateau, M Fromant, J M Schmitter, J M Buhler, S Blanquet Journal of Bacteriology 171 (12), 6437-6445, 1989-12

...of a second Ap4A phosphorylase activity in yeast cells....

DOI Web Site 被引用文献2件

J Charlier, R Sanchez Biochemical Journal 248 (1), 43-51, 1987-11-15

...Ap4A synthesis was measured by a new assay using DEAE-cellulose filters....

DOI PDF 被引用文献1件

Morioka,M., Shimada,H. Zoological science 3 (6), 1049-, 1986-12-15

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森岡,瑞枝, 嶋田,拓 動物学雑誌 92 (4), 491-, 1983-12-25

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H Flodgaard, H Klenow Biochemical Journal 208 (3), 737-742, 1982-12-15

...In the present paper human platelets have been shown to contain relatively large amounts of Ap4A....

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Adaling Ogilvie Analytical Biochemistry 115 (2), 302-307, 1981-08

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E Rapaport, P C Zamecnik Proceedings of the National Academy of Sciences 73 (11), 3984-3988, 1976-11

...The metabolic lability of Ap4A is also demonstrated by its rapid depletion after decreases in the ATP/ADP ratio....

DOI Web Site 被引用文献1件

Morioka,M., Shimada,H. Zoological science 1 (6), 939-,

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