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  • Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation

    Mostafa Mahmoud, Elsadek Nehal E., Emam Sherif E., Ando Hidenori, Shimizu Taro, Abdelkader Hamdy, Ishima Yu, Aly Usama Farghaly, Sarhan Hatem A., Ishida Tatsuhiro Biological & Pharmaceutical Bulletin 45 (1), 129-135, 2022-01-01

    ...antibodies (mAbs); HIK-M11 mAbs; and antiserum containing polyclonal anti-PEG IgMs. 1,2-Distearoyl-<i>sn</i>-glycero-3-phosphoethanolamine-<i>n</i>-[methoxy (polyethylene glycol)-2000] (mPEG<sub>2000</sub>-DSPE...

    DOI Web Site Web Site ほか1件 参考文献36件

  • Design of a Novel PEGylated Liposomal Vector for Systemic Delivery of siRNA to Solid Tumors

    Song Furan, Sakurai Naoyuki, Okamoto Ayaka, Koide Hiroyuki, Oku Naoto, Dewa Takehisa, Asai Tomohiro Biological & Pharmaceutical Bulletin 42 (6), 996-1003, 2019-06-01

    ...The <i>in vivo</i> effects of PEGylation were observed only when distearoylphosphatidylethanolamine (DSPE)-PEG but not distearoylglycerol (DSG)-PEG were used....

    DOI Web Site Web Site ほか2件 被引用文献3件 参考文献22件

  • Targeting c-MYC in Platinum-Resistant Ovarian Cancer

    Jeyshka M. Reyes-González, Guillermo N. Armaiz-Peña, Lingegowda S. Mangala, Fatma Valiyeva, Cristina Ivan, Sunila Pradeep, Ileabett M. Echevarría-Vargas, Adrian Rivera-Reyes, Anil K. Sood, Pablo E. Vivas-Mejía Molecular Cancer Therapeutics 14 (10), 2260-2269, 2015-10-01

    ...In addition, single weekly doses of c-MYC–siRNA incorporated into 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG...

    DOI PDF 被引用文献1件

  • Sensitizing cancer cells to TRAIL-induced death by micellar delivery of mitoxantrone

    Taraka Sai Pavan Grandhi, Thrimoorthy Potta, David J Taylor, Yanqing Tian, Roger H Johnson, Deirdre R Meldrum, Kaushal Rege Nanomedicine 9 (12), 1775-1788, 2014-08

    ...Mitoxantrone, a previously unknown TRAIL sensitizer identified in the screen, was successfully encapsulated in methoxy-, amine- and carboxyl-terminated PEG-DSPE micelles in order to facilitate delivery...

    DOI Web Site 被引用文献1件

  • Terpene-Containing PEGylated Liposomes as Transdermal Carriers of a Hydrophilic Compound

    Rangsimawong Worranan, Opanasopit Praneet, Rojanarata Theerasak, Ngawhirunpat Tanasait Biological & Pharmaceutical Bulletin 37 (12), 1936-1943, 2014

    ...PLs composed of <i>N</i>-(carbonyl-methoxypolyethyleneglycol-2000)–1,2-distearoyl-<i>sn</i>-glycero-3-phosphoethanolamine (PEG<sub>2000</sub>–DSPE), the sodium salt of PEG<sub>2000</sub>–DSPE, phosphatidylcholine...

    DOI Web Site Web Site ほか2件 被引用文献4件 参考文献30件

  • 感染症におけるDDSの応用と将来の展望  アムホテリシンB封入イムノリポソーム

    丸山 一雄, 滝澤 知子, 鈴木 亮, 宇都口 直樹 Drug Delivery System 21 (5), 516-522, 2006

    ポリエンマクロライド系抗真菌剤であるアムホテリシンB (AmB) は, 深在性真菌症の治療に用いられているが, 腎障害などの重篤な副作用を示すため, その使用に制限がある. したがって, DDSによる副作用の軽減が望まれている. AmBは水やほとんどの有機溶媒に不溶なため, そのリポソーム化は困難であったが, ポリエチレングリコールのリン脂質誘導体 (DSPE-PEG) と9% …

    DOI Web Site 医中誌 参考文献27件

  • リポソームの肝移行に及ぼすラット血清アルブミンの影響

    古本 健太朗, 天野 小百合, 東 由子, 横江 淳一, 大河原 賢一, 檜垣 和孝, 甲斐 俊哉, 木村 聰城郎 日本薬物動態学会年会講演要旨集 18 (0), 177-177, 2003

    ...<BR>【方法】リポソームは Egg phosphatidylcholine (EPC):Cholesterol (Chol):N-glutaryl phosphatidylethanolamine (NGPE)=60:30:10 及び EPC:Chol:NGPE:PEG2000-DSPE=55:30:10:5 の組成となるように調製し、トレーサーとして [<SUP>3</SUP>H] Cholesteryl...

    DOI

  • PEG-Immunoliposome

    Kazuo Maruyama Bioscience Reports 22 (2), 251-266, 2002-04-01

    ....% of DSPE-PEG-COOH or DPPE-PEG-Mal....

    DOI PDF 被引用文献9件

  • Physicochemical Properties of PEG-Grafted Liposomes.

    Sriwongsitanont Supaporn, Ueno Masaharu CHEMICAL & PHARMACEUTICAL BULLETIN 50 (9), 1238-1244, 2002

    ...The permeability for calcein increased with increase in concentration of distearoylphosphatidylethanolamine (DSPE)-PEG....

    DOI Web Site Web Site ほか1件 被引用文献7件 参考文献66件

  • In Vivo Targeting by Liposomes.

    MARUYAMA Kazuo Biological & Pharmaceutical Bulletin 23 (7), 791-799, 2000

    ...Small unilamellar liposomes (90-130 nm in diameter) were prepared from phosphatidylcholine and cholesterol (2 : 1, m/m) containing 6 mol% of DSPE-PEG-COOH or DPPE-PEG-Mal....

    DOI Web Site Web Site ほか2件 被引用文献4件 参考文献49件

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