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Nakamura Motoki, Uemura Kentaro, Saito-Tarashima Noriko, Sato Akihiko, Orba Yasuko, Sawa Hirofumi, Matsuda Akira, Maenaka Katsumi, Minakawa Noriaki ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 70 (3), 220-225, 2022-03-01

...<p>We previously showed that 5-ethynyl-(1-β-D-ribofuranosyl)imidazole-4-carboxamide (<b>1</b>; EICAR) is a potent anti-dengue virus (DENV) compound but is cytotoxic to some cell lines, while its 4-thio...

DOI Web Site PubMed ほか1件 参考文献29件

Yannick Debing, Suzanne U. Emerson, Yijin Wang, Qiuwei Pan, Jan Balzarini, Kai Dallmeier, Johan Neyts Antimicrobial Agents and Chemotherapy 58 (1), 267-273, 2014-01

...depletion of intracellular GTP pools, which is evident from the facts that (i) other GTP-depleting agents (5-ethynyl-1-β- <jats:sc>d</jats:sc> -ribofuranosylimidazole-4-carboxamide [EICAR...

DOI Web Site 被引用文献4件

Fabiana Dal Pozzo, Viola Galligioni, Francesca Vaccari, Laura Gallina, Mara Battilani, Alessandra Scagliarini Research in Veterinary Science 88 (2), 339-344, 2010-04

DOI Web Site Web Site 被引用文献1件

M. C. Georges-Courbot, H. Contamin, C. Faure, P. Loth, S. Baize, P. Leyssen, J. Neyts, V. Deubel Antimicrobial Agents and Chemotherapy 50 (5), 1768-1772, 2006-05

...We report here that EICAR, the 5-ethynyl analogue of ribavirin, and the OMP-decarboxylase inhibitors 6-aza-uridine and pyrazofurin have strong antiviral activity against Nipah virus replication in vitro...

DOI Web Site 被引用文献1件

Pieter Leyssen, Jan Balzarini, Erik De Clercq, Johan Neyts Journal of Virology 79 (3), 1943-1947, 2005-02

...A linear correlation was observed over a broad concentration range between the antiviral activities of ribavirin, EICAR, and MPA and the effects of these compounds on GTP pool depletion....

DOI Web Site 被引用文献4件

Erik De Clercq Clinical Microbiology Reviews 14 (2), 382-397, 2001-04

...., EICAR); (ii) SAH hydrolase inhibitors (e.g., 5′-noraristeromycin, 3-deazaneplanocin A, and various neplanocin A derivatives); (iii) OMP decarboxylase inhibitors (e.g., pyrazofurin) and CTP synthetase...

DOI Web Site 被引用文献1件

M Jashés, G Mlynarz, E De Clercq, A.M Sandino Antiviral Research 45 (1), 9-17, 2000-01

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Noriaki Minakawa, Akira Matsuda Current Medicinal Chemistry 6 (7), 615-628, 1999-07

...The mode of action of EICAR is also discussed.</jats:p> </jats:sec>...

DOI Web Site Web Site 被引用文献1件

J. Balzarini, L. Stet, A. Matsuda, L. Wiebe, E. Knauss, E. De Clercq Advances in Experimental Medicine and Biology 723-728, 1998

DOI Web Site 被引用文献1件

Noriaki Minakawa, Akira Matsuda, Zuping Xia, Leonard I. Wiebe, Edward E. Knaus Journal of Labelled Compounds and Radiopharmaceuticals 38 (9), 809-824, 1996-09

DOI Web Site Web Site 被引用文献1件

MORI SHUICHI, WATANABE WATARU, SHIGETA SHIRO The Tohoku Journal of Experimental Medicine 177 (4), 315-325, 1995

...The 50% effective concentration (EC₅₀) of 1-β-D-ribofuranosyl- 1, 2, 4-triazol-3-carboxamide (ribavirin) and 5-ethynyl-1-β-D-ribofuranosyl- imidazole-4-carboxamide (EICAR) against orthomyxo-...

DOI Web Site PubMed

Y. Kosugi, Y. Saito, S. Mori, J. Watanabe, M. Baba, S. Shigeta Antiviral Chemistry and Chemotherapy 5 (6), 366-371, 1994-12

...EICAR and mycophenolic acid showed higher potency than mizoribine and ribavirin against all myxoviruses examined....

DOI Web Site 被引用文献3件

J Balzarini, A Karlsson, L Wang, C Bohman, K Horská, I Votruba, A Fridland, A Van Aerschot, P Herdewijn, E De Clercq Journal of Biological Chemistry 268 (33), 24591-24598, 1993-11

DOI Web Site Web Site 被引用文献2件

S Shigeta, S Mori, M Baba, M Ito, K Honzumi, K Nakamura, H Oshitani, Y Numazaki, A Matsuda, T Obara Antimicrobial Agents and Chemotherapy 36 (2), 435-439, 1992-02

...The 50% virus-inhibitory concentrations of EICAR and TJ13025 were generally within the 0.1- to 1-microgram/ml range....

DOI Web Site 被引用文献1件

E De Clercq, M Cools, J Balzarini, R Snoeck, G Andrei, M Hosoya, S Shigeta, T Ueda, N Minakawa, A Matsuda Antimicrobial Agents and Chemotherapy 35 (4), 679-684, 1991-04

...EICAR inhibited vaccinia virus tail lesion formation at doses that were not toxic to the host....

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Noriaki Minakawa, Takayuki Takeda, Takuma Sasaki, Akira Matsuda, Tohru Ueda Journal of Medicinal Chemistry 34 (2), 778-786, 1991-02

DOI Web Site 被引用文献6件