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  • Polypill Strategy in Secondary Cardiovascular Prevention

    Jose M. Castellano, Stuart J. Pocock, Deepak L. Bhatt, Antonio J. Quesada, Ruth Owen, Antonio Fernandez-Ortiz, Pedro L. Sanchez, Francisco Marin Ortuño, Jose M. Vazquez Rodriguez, Alexandra Domingo-Fernández, Iñigo Lozano, Maria C. Roncaglioni, Marta Baviera, Andreana Foresta, Luisa Ojeda-Fernandez, Furio Colivicchi, Stefania A. Di Fusco, Wolfram Doehner, Antje Meyer, François Schiele, Fiona Ecarnot, Aleš Linhart, Jean-Claude Lubanda, Gyorgy Barczi, Bela Merkely, Piotr Ponikowski, Marta Kasprzak, Juan M. Fernandez Alvira, Vicente Andres, Hector Bueno, Timothy Collier, Frans Van de Werf, Pablo Perel, Moises Rodriguez-Manero, Angeles Alonso Garcia, Marco Proietti, Mikkel M. Schoos, Tabassome Simon, Jose Fernandez Ferro, Nicolas Lopez, Ettore Beghi, Yannick Bejot, David Vivas, Alberto Cordero, Borja Ibañez, Valentin Fuster New England Journal of Medicine 387 (11), 967-977, 2022-09-15

    DOI Web Site 被引用文献2件

  • Multidimensional tropical forest recovery

    Lourens Poorter, Dylan Craven, Catarina C. Jakovac, Masha T. van der Sande, Lucy Amissah, Frans Bongers, Robin L. Chazdon, Caroline E. Farrior, Stephan Kambach, Jorge A. Meave, Rodrigo Muñoz, Natalia Norden, Nadja Rüger, Michiel van Breugel, Angélica María Almeyda Zambrano, Bienvenu Amani, José Luis Andrade, Pedro H. S. Brancalion, Eben N. Broadbent, Hubert de Foresta, Daisy H. Dent, Géraldine Derroire, Saara J. DeWalt, Juan M. Dupuy, Sandra M. Durán, Alfredo C. Fantini, Bryan Finegan, Alma Hernández-Jaramillo, José Luis Hernández-Stefanoni, Peter Hietz, André B. Junqueira, Justin Kassi N’dja, Susan G. Letcher, Madelon Lohbeck, René López-Camacho, Miguel Martínez-Ramos, Felipe P. L. Melo, Francisco Mora, Sandra C. Müller, Anny E. N’Guessan, Florian Oberleitner, Edgar Ortiz-Malavassi, Eduardo A. Pérez-García, Bruno X. Pinho, Daniel Piotto, Jennifer S. Powers, Susana Rodríguez-Buriticá, Danaë M. A. Rozendaal, Jorge Ruíz, Marcelo Tabarelli, Heitor Mancini Teixeira, Everardo Valadares de Sá Barretto Sampaio, Hans van der Wal, Pedro M. Villa, Geraldo W. Fernandes, Braulio A. Santos, José Aguilar-Cano, Jarcilene S. de Almeida-Cortez, Esteban Alvarez-Davila, Felipe Arreola-Villa, Patricia Balvanera, Justin M. Becknell, George A. L. Cabral, Carolina Castellanos-Castro, Ben H. J. de Jong, Jhon Edison Nieto, Mário M. Espírito-Santo, Maria C. Fandino, Hernando García, Daniel García-Villalobos, Jefferson S. Hall, Alvaro Idárraga, Jaider Jiménez-Montoya, Deborah Kennard, Erika Marín-Spiotta, Rita Mesquita, Yule R. F. Nunes, Susana Ochoa-Gaona, Marielos Peña-Claros, Nathalia Pérez-Cárdenas, Jorge Rodríguez-Velázquez, Lucía Sanaphre Villanueva, Naomi B. Schwartz, Marc K. Steininger, Maria D. M. Veloso, Henricus F. M. Vester, Ima C. G. Vieira, G. Bruce Williamson, Kátia Zanini, Bruno Hérault Science 374 (6573), 1370-1376, 2021-12-10

    <jats:title>Resilient secondary tropical forests?</jats:title> <jats:p> Although deforestation is rampant across the tropics, forest has a strong capacity to regrow on …

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  • Identification of 22 susceptibility loci associated with testicular germ cell tumors

    John Pluta, Louise C. Pyle, Kevin T. Nead, Rona Wilf, Mingyao Li, Nandita Mitra, Benita Weathers, Kurt D’Andrea, Kristian Almstrup, Lynn Anson-Cartwright, Javier Benitez, Christopher D. Brown, Stephen Chanock, Chu Chen, Victoria K. Cortessis, Alberto Ferlin, Carlo Foresta, Marija Gamulin, Jourik A. Gietema, Chiara Grasso, Mark H. Greene, Tom Grotmol, Robert J. Hamilton, Trine B. Haugen, Russ Hauser, Michelle A. T. Hildebrandt, Matthew E. Johnson, Robert Karlsson, Lambertus A. Kiemeney, Davor Lessel, Ragnhild A. Lothe, Jennifer T. Loud, Chey Loveday, Paloma Martin-Gimeno, Coby Meijer, Jérémie Nsengimana, David I. Quinn, Thorunn Rafnar, Shweta Ramdas, Lorenzo Richiardi, Rolf I. Skotheim, Kari Stefansson, Clare Turnbull, David J. Vaughn, Fredrik Wiklund, Xifeng Wu, Daphne Yang, Tongzhang Zheng, Andrew D. Wells, Struan F. A. Grant, Ewa Rajpert-De Meyts, Stephen M. Schwartz, D. Timothy Bishop, Katherine A. McGlynn, Peter A. Kanetsky, Katherine L. Nathanson, Christian Kubisch Nature Communications 12 (1), 2021-07-23

    <jats:title>Abstract</jats:title><jats:p>Testicular germ cell tumors (TGCT) are the most common tumor in young white men and have a high heritability. In this study, the international Testicular …

    DOI PDF Web Site 被引用文献1件

  • The 6-min walk test as a new outcome measure in Amyotrophic lateral sclerosis

    Massimo Russo, Christian Lunetta, Riccardo Zuccarino, Gian L. Vita, Maria Sframeli, Andrea Lizio, Stefania La Foresta, Cristina Faraone, Valeria A. Sansone, Giuseppe Vita, Sonia Messina Scientific Reports 10 (1), 2020-09-23

    <jats:title>Abstract</jats:title><jats:p>One of the issues highlighted in amyotrophic lateral sclerosis (ALS) clinical trials is the lack of appropriate outcome measures. The aim of this …

    DOI PDF Web Site 被引用文献1件

  • The Piancaldoli meteorite: A forgotten primitive LL3.10 ordinary chondrite

    Yves Marrocchi, Lydie Bonal, Jérome Gattacceca, Laurette Piani, Pierre Beck, Richard Greenwood, Jolantha Eschrig, Anne Basque, Pasquale Mario Nuccio, Franco Foresta Martin Meteoritics & Planetary Science 55 (8), 1-, 2020-08

    <jats:title>Abstract</jats:title><jats:p>The Piancaldoli ordinary chondrite fell in northern Italy on August 10, 1968. Preliminary studies led to its classification as an LL3.4 unequilibrated …

    DOI Web Site Web Site 被引用文献1件

  • 「QOL座標理論」補遺,スピリチュアリティ論考

    野尻 雅美 日本健康医学会雑誌 29 (1), 3-8, 2020-04-30

    <p>スピリチュアリティに関する主要な4書と2人の専門家による記述を精読した結果,『スピリチュアリティは無意識の深層にある』とした。禅などにより心の本地に「還帰」することにより,また「接近」することで,いのちの実相が甦り,高いスピリチュアリティになる。それが意識の世界に顕現し,「高いQOL」となり,「幸せな人生」,「美しい人生」へとつながる。</p>

    DOI Web Site 医中誌

  • QOL座標理論の基礎と展開,新しいQOD概念へ

    野尻 雅美 日本健康医学会雑誌 28 (2), 98-106, 2019-07-26

    <p>私は本論文で,抽象的で難解な概念であるQOLを座標化しました。これがQOL座標です。これによりQOLは視覚化され,論理的に理解ができ,万人に共有が可能となりました。座標化の展開は,QOLプロモーションから,ケア論,看護論,人間研究,エイジング曲線などに徐々に広げてゆき,近時は老年的超越にまで広げました。またこれまでに誰もが触れていない「あの世」についても試み,さらに新しいQODの概念にも言…

    DOI Web Site 医中誌

  • Characteristics of a nationwide cohort of patients presenting with isolated hypogonadotropic hypogonadism (IHH)

    Marco Bonomi, Valeria Vezzoli, Csilla Krausz, Fabiana Guizzardi, Silvia Vezzani, Manuela Simoni, Ivan Bassi, Paolo Duminuco, Natascia Di Iorgi, Claudia Giavoli, Alessandro Pizzocaro, Gianni Russo, Mirella Moro, Letizia Fatti, Alberto Ferlin, Laura Mazzanti, Maria Chiara Zatelli, Salvo Cannavò, Andrea M Isidori, Angela Ida Pincelli, Flavia Prodam, Antonio Mancini, Paolo Limone, Maria Laura Tanda, Rossella Gaudino, Mariacarolina Salerno, Pregnolato Francesca, Mohamad Maghnie, Mario Maggi, Luca Persani, _ _, G Aimaretti, M Altobelli, M R Ambrosio, M Andrioli, G Angeletti, F Arecco, G Arnaldi, M Arosio, A Balsamo, M Baldassarri, L Bartalena, N Bazzoni, L Beccaria, P Beck-Peccoz, G Bellastella, M Bellizzi, F Benedicenti, S Bernasconi, C Bizzarri, G Bona, S Bonadonna, G Borretta, M Boschetti, A Brunani, V Brunelli, F Buzi, C Cacciatore, B Cangiano, M Cappa, R Casalone, A Cassio, P Cavarzere, V Cherubini, T Ciampani, D Cicognani, A Cignarelli, M Cisternino, P Colombo, S Corbetta, N Corciulo, G Corona, R Cozzi, C Crivellaro, I Dalle Mule, L Danesi, A V D’Elia, E degli Uberti, S De Leo, E Della Valle, M De Marchi, N Di Iorgi, A Di Mambro, A Fabbri, C Foresta, G Forti, A R Franceschi, A Garolla, M Ghezzi, C Giacomozzi, M Giusti, E Grosso, G Guabello, M P Guarneri, G Grugni, A M Isidori, F Lanfranco, A Lania, R Lanzi, L Larizza, A Lenzi, S Loche, P Loli, V Lombardi, M C Maggio, G Mandrile, C Manieri, G Mantovani, S Marelli, M Marzullo, M A Mencarelli, N Migone, G Motta, G Neri, G Padova, G Parenti, B Pasquino, A Pia, E Piantanida, E Pignatti, A Pilotta, B Pivetta, M Pollazzon, A Pontecorvi, P Porcelli, G B Pozzan, G Pozzobon, G Radetti, P Razzore, L Rocchetti, R Roncoroni, G Rossi, E Sala, A Salvatoni, F Salvini, A Secco, M Segni, R Selice, P Sgaramella, F Sileo, A A Sinisi, F Sirchia, A Spada, A Tresoldi, R Vigneri, G Weber, S Zucchini European Journal of Endocrinology 178 (1), 23-32, 2018-01

    <jats:sec> <jats:title>Objective</jats:title> <jats:p>Isolated hypogonadotropic hypogonadism (IHH) is a rare disorder with pubertal delay, normal (normoosmic-IHH, nIHH) or defective sense of smell …

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  • Expanded access program with Nusinersen in SMA type I in Italy: Strengths and pitfalls of a successful experience

    Sonia Messina, Marika Pane, Valeria Sansone, Claudio Bruno, Michela Catteruccia, Giuseppe Vita, Concetta Palermo, Emilio Albamonte, Marina Pedemonte, Enrico Bertini, Luca Binetti, Eugenio Mercuri, Daniela Lauro, Anita Pallara, Simona Spinoglio, Maria Letizia Solinas, Grazia Zappa, Francesca Penno, Cristina Ponzanelli, Jacopo Casiraghi, Marcello Villanova, Danilo Tiziano, Anna Mandelli, Chiara Mastella, Alberto Fontana, Anna Ambrosini, Daniela Leone, Roberto de Sanctis, Nicola Forcina, Marco Piastra, Orazio Genovese, Alessandro Pedicelli, Maria Sframeli, Antonio Versaci, Imma Rulli, Eloisa Gitto, Cristina Faraone, Stefania La Foresta, Maria Macrì, Adele D'Amico, Giulia Colia, Anna Maria Bonetti, Adelina Carlesi, Renato Cutrera, Maria Beatrice Chiarini, Marta Ferretti, Alberto Garaventa, Giovanni Montobbio, Carlo Gandolfo, Valentina Iurilli, Paola Tacchetti, Emilia Bobeica, Alessia D'Agostino, Alice Pirola, Sara Luppone, Elisa De Mattia, Elisa Falcier, Fabrizio Rao, Fausto Fedeli, Luca Mancini, Paolo Stoia, Maurizio Heinen, Valeria Cozzi, Beatrice Travaglia, Emma Mizzotti Neuromuscular Disorders 27 (12), 1084-1086, 2017-12

    DOI Web Site Web Site 被引用文献1件

  • Osteocalcin and Sex Hormone Binding Globulin Compete on a Specific Binding Site of GPRC6A

    Luca De Toni, Diego Guidolin, Vincenzo De Filippis, Simone Tescari, Giacomo Strapazzon, Maria Santa Rocca, Alberto Ferlin, Mario Plebani, Carlo Foresta Endocrinology 157 (11), 4473-4486, 2016-09-27

    <jats:p>The undercarboxylated form of osteocalcin (ucOC) regulates male fertility and energy metabolism, acting through the G protein-coupled receptor (GPRC)6A, thus forming a new …

    DOI PDF 被引用文献1件

  • Polymorphism rs2274911 of GPRC6A as a Novel Risk Factor for Testis Failure

    Luca De Toni, Andrea Di Nisio, Elena Speltra, Maria Santa Rocca, Marco Ghezzi, Daniela Zuccarello, Nunzio Turiaco, Alberto Ferlin, Carlo Foresta The Journal of Clinical Endocrinology & Metabolism 101 (3), 953-961, 2016-03-01

    <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Context:</jats:title> <jats:p>The G protein-coupled receptor GPRC6A is an emerging …

    DOI PDF 被引用文献1件

  • Conventional and Nuclear Medicine Imaging in Ectopic Cushing's Syndrome: A Systematic Review

    Andrea M. Isidori, Emilia Sbardella, Maria Chiara Zatelli, Mara Boschetti, Giovanni Vitale, Annamaria Colao, Rosario Pivonello, N. Albiger, A. Ambrogio, G. Arnaldi, E. Arvat, R. Berardelli, M. Boscaro, M. Boschetti, S. Cannavò, F. Cavagnini, A. Colao, S. M. Corsello, A. Cozzolino, M. De Leo, C. Di Somma, K. Esposito, D. Ferone, C. Foresta, F. Gatto, C. Giordano, D. Giugliano, C. Graziadio, A. M. Isidori, P. Loli, L. Manetti, M. Mannelli, P. Marzullo, F. Mantero, F. Minuto, R. M. Paragliola, F. Pecori Giraldi, R. Pivonello, G. Reimondo, C. Scaroni, A. Scillitani, C. Simeoli, A. Stigliano, M. Terzolo, F. Tortora, L. Trementino, G. Vitale, M. C. Zatelli The Journal of Clinical Endocrinology & Metabolism 100 (9), 3231-3244, 2015-09

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  • OSAS Surgery and Postoperative Discomfort: Phase I Surgery versus Phase II Surgery

    Giulio Gasparini, Andrea Torroni, Francesco Di Nardo, Sandro Pelo, Enrico Foresta, Roberto Boniello, Mario Romandini, Daniele Cervelli, Camillo Azzuni, Tito Matteo Marianetti BioMed Research International 2015 1-7, 2015

    <jats:p><jats:italic>Introduction</jats:italic>. This study aims to investigate the reasons that discourage the patients affected by OSAS to undergo orthognathic surgery and compares the …

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  • Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

    Simona Blotta, Jana Jakubikova, Teresa Calimeri, Aldo M. Roccaro, Nicola Amodio, Abdel Kareem Azab, Umberto Foresta, Constantine S. Mitsiades, Marco Rossi, Katia Todoerti, Stefano Molica, Fortunato Morabito, Antonino Neri, Piersandro Tagliaferri, Pierfrancesco Tassone, Kenneth C. Anderson, Nikhil C. Munshi Blood 120 (25), 5002-5013, 2012-12-13

    <jats:title>Abstract</jats:title> <jats:p>The Hedgehog (Hh) pathway is required for cell-fate determination during the embryonic life, as well as cell growth and differentiation in …

    DOI PDF 被引用文献3件

  • Effect of Relaxin on Human Sperm Functions

    Alberto Ferlin, Massimo Menegazzo, Lisa Gianesello, Riccardo Selice, Carlo Foresta Journal of Andrology 33 (3), 474-482, 2012-05-06

    <jats:p><jats:bold>ABSTRACT: </jats:bold> Relaxin is a circulating hormone with functions in pregnancy, parturition, and other aspects of female reproduction. It is also secreted from the prostate …

    DOI Web Site Web Site 被引用文献1件

  • Insulin‐like factor 3 as a marker of testicular function in obese men

    Carlo Foresta, Antonella Di Mambro, Claudio Pagano, Andrea Garolla, Roberto Vettor, Alberto Ferlin Clinical Endocrinology 71 (5), 722-726, 2009-10-05

    <jats:title>Summary</jats:title><jats:p><jats:bold>Objectives </jats:bold> Testicular function declines with obesity as a result of central and peripheral mechanisms, including a primary dysfunction …

    DOI Web Site Web Site 被引用文献6件

  • INSL3/RXFP2 Signaling in Testicular Descent

    Shu Feng, Alberto Ferlin, Anne Truong, Ross Bathgate, John D. Wade, Sean Corbett, Shuo Han, Mounia Tannour‐Louet, Dolores J. Lamb, Carlo Foresta, Alexander I. Agoulnik Annals of the New York Academy of Sciences 1160 (1), 197-204, 2009-04

    <jats:p>Mutations of the insulin‐like peptide 3 (INSL3) hormone or its receptor, RXFP2, cause intraabdominal cryptorchidism in male mice. Specific RXFP2 expression in mouse gubernacula was detected …

    DOI Web Site Web Site 被引用文献1件

  • New Roles for INSL3 in Adults

    Alberto Ferlin, Anastasia Pepe, Lisa Gianesello, Andrea Garolla, Shu Feng, Arianna Facciolli, Roy Morello, Alexander I. Agoulnik, Carlo Foresta Annals of the New York Academy of Sciences 1160 (1), 215-218, 2009-04

    <jats:p>Insulin‐like factor 3 (INSL3) is produced primarily by testicular Leydig cells and acts by binding to its specific G‐protein‐coupled receptor, RXFP2 (relaxin family peptide 2). INSL3 is …

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  • Comparative Analysis of DNA Repair in Stem and Nonstem Glioma Cell Cultures

    Monica Ropolo, Antonio Daga, Fabrizio Griffero, Mara Foresta, Gianluigi Casartelli, Annalisa Zunino, Alessandro Poggi, Enrico Cappelli, Gianluigi Zona, Renato Spaziante, Giorgio Corte, Guido Frosina Molecular Cancer Research 7 (3), 383-392, 2009-03-17

    <jats:title>Abstract</jats:title> <jats:p>It has been reported that cancer stem cells may contribute to glioma radioresistance through preferential activation of the DNA damage …

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  • Role of Hormones, Genes, and Environment in Human Cryptorchidism

    Carlo Foresta, Daniela Zuccarello, Andrea Garolla, Alberto Ferlin Endocrine Reviews 29 (5), 560-580, 2008-08-01

    <jats:title>Abstract</jats:title><jats:p>Cryptorchidism is the most frequent congenital birth defect in male children (2–4% in full-term male births), and it has the potential to impact the health …

    DOI PDF 被引用文献8件

  • Mutations in the Insulin-Like Factor 3 Receptor Are Associated With Osteoporosis

    Alberto Ferlin, Anastasia Pepe, Lisa Gianesello, Andrea Garolla, Shu Feng, Sandro Giannini, Manuela Zaccolo, Arianna Facciolli, Roy Morello, Alexander I Agoulnik, Carlo Foresta Journal of Bone and Mineral Research 23 (5), 683-693, 2008-05-01

    <jats:title>Abstract</jats:title> <jats:p>Introduction: Insulin-like factor 3 (INSL3) is produced primarily by testicular Leydig cells. It acts by binding to its specific G …

    DOI PDF Web Site 被引用文献4件

  • Population genetics of the frog-killing fungus <i>Batrachochytrium dendrobatidis</i>

    Jess A. T. Morgan, Vance T. Vredenburg, Lara J. Rachowicz, Roland A. Knapp, Mary J. Stice, Tate Tunstall, Rob E. Bingham, John M. Parker, Joyce E. Longcore, Craig Moritz, Cheryl J. Briggs, John W. Taylor Proceedings of the National Academy of Sciences 104 (34), 13845-13850, 2007-08-21

    <jats:p> Global amphibian decline by chytridiomycosis is a major environmental disaster that has been attributed to either recent fungal spread or environmental change that promotes …

    DOI Web Site 被引用文献2件

  • Oestrogen stimulates endothelial progenitor cells via oestrogen receptor‐α

    Carlo Foresta, Daniela Zuccarello, Andrea Biagioli, Luca De Toni, Elisa Prana, Valentina Nicoletti, Guido Ambrosini, Alberto Ferlin Clinical Endocrinology 67 (4), 520-525, 2007-05-24

    <jats:title>Summary</jats:title><jats:p><jats:bold>Context </jats:bold> Oestrogens play an important protective role on the vascular system. The endothelial cell layer is a direct target for these …

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  • Changes in Serum Insulin-Like Factor 3 during Normal Male Puberty

    Alberto Ferlin, Andrea Garolla, Franco Rigon, Lucia Rasi Caldogno, Andrea Lenzi, Carlo Foresta The Journal of Clinical Endocrinology & Metabolism 91 (9), 3426-3431, 2006-09-01

    <jats:title>Abstract</jats:title> <jats:p>Context: Insulin-like factor 3 (INSL3) is produced by the Leydig cells, and in adults, its secretion is dependent on the state of …

    DOI PDF 被引用文献9件

  • Androgen receptor gene CAG and GGC repeat lengths in cryptorchidism

    Alberto Ferlin, Andrea Garolla, Andrea Bettella, Lucia Bartoloni, Cinzia Vinanzi, Alberto Roverato, Carlo Foresta European Journal of Endocrinology 152 (3), 419-425, 2005-03

    <jats:p><jats:italic>Objective</jats:italic>: Cryptorchidism is the most common congenital birth defect in male children, and accumulating evidence suggests that genetic abnormalities may be …

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  • 豊田フォレスタヒルズの渓流におけるAlの流出(__II__)

    金 ミンシク, 竹中 千里, 吉田 恭司, 朴 ホタク 日本林学会大会発表データベース 114 (0), 287-287, 2003

    1. 緒論愛知県豊田市の豊田フォレスタヒルズの渓流水のpH値は約6__から__7で、一般的な渓流水の安定した数値を示しているにもかかわらず、土壌の酸性化によって溶出する物質であるアルミニウム濃度は他の渓流水と比較して約10__から__100倍高く、その流出メカニズムは非常に興味深い。前回はろ過の際のフィルタ孔径の違いによる分析結果の解析から、0.20m__から__0.45mの大きさのAl, …

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  • Role of P2-purinergic receptors in rat Leydig cell steroidogenesis

    Carlo FORESTA, Marco ROSSATO, Andrea NOGARA, Francesco GOTTARDELLO, Paola BORDON, Francesco DI VIRGILIO Biochemical Journal 320 (2), 499-504, 1996-12-01

    <jats:p>The present study investigated the effects of extracellular ATP on the intracellular calcium ion concentration ([Ca2+]i) and testosterone production in isolated adult rat Leydig cells. This …

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  • Mechanism of human sperm activation by extracellular ATP

    C. Foresta, M. Rossato, P. Chiozzi, F. Di Virgilio American Journal of Physiology-Cell Physiology 270 (6), C1709-C1714, 1996-06-01

    <jats:p>We have identified the mechanism whereby extracellular ATP (ATPe) triggers the acrosome reaction in human spermatozoa. This nucleotide opens a ligand-gated ion channel expressed on the sperm …

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