検索結果 289 件

石丸 和佳, 鶴田 朗人, 吉田 優哉, 松永 直哉, 小柳 悟, 大戸 茂弘 日本臨床薬理学会学術総会抄録集 44 (0), 3-C-O16-3-, 2023

...MΦ選択的BMAL1 KOマウス（<i>Bmal1</i>cKOマウス）は、<i>LysM-Cre</i>マウスと<i>Bmal1 ^fl/fl</i>マウスを掛け合わせて作製した。慢性肝炎モデルマウスはDiethylnitrosamine (DEN) 80 mg/L含有水を13週間飲水投与することで作製した。MΦ分化の解析にはフローサイトメーターを用いた。...

DOI

Momoko Takagi, Kei Hotamori, Keigo Naito, Sumire Matsukawa, Mayumi Egusa, Yoko Nishizawa, Yuri Kanno, Mitsunori Seo, Shinsuke Ifuku, Akira Mine, Hironori Kaminaka Frontiers in Plant Science 13 2022-11-28

...The disruption of genes for lysin motif (LysM)-containing chitin receptors, OsCERK1 (Chitin elicitor receptor kinase 1) and OsCEBiP (Chitin elicitor-binding protein), compromised chitin-induced systemic...

DOI Web Site 参考文献65件

Bhaba K Das, Lei Wang, Toshifumi Fujiwara, Jian Zhou, Nukhet Aykin-Burns, Kimberly J Krager, Renny Lan, Samuel G Mackintosh, Ricky Edmondson, Michael L Jennings, Xiaofang Wang, Jian Q Feng, Tomasa Barrientos, Jyoti Gogoi, Aarthi Kannan, Ling Gao, Weirong Xing, Subburaman Mohan, Haibo Zhao eLife 11 2022-06-27

...Consistent with this gender-dependent phenomena, estrogen deficiency induced by ovariectomy decreased trabecular bone mass in Tfr1<jats:sup>ΔLysM</jats:sup> mice....

DOI PDF Web Site ほか1件 参考文献78件

Miyata Kana, Hasegawa Shun, Nakajima Emi, Nishizawa Yoko, Kamiya Kota, Yokogawa Hirotaka, Shirasaka Subaru, Maruyama Shingo, Shibuya Naoto, Kaku Hanae Ｐｌａｎｔ　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ 39 (2), 119-128, 2022-06-25

...<p>In rice, the lysin motif (LysM) receptor-like kinase OsCERK1, originally identified as the essential molecule for chitin-triggered immunity, plays a key role in arbuscular mycorrhizal (AM) symbiosis...

DOI Web Site Web Site 被引用文献2件 参考文献36件

Annie Lebreton, Nianwu Tang, Alan Kuo, Kurt LaButti, William Andreopoulos, Elodie Drula, Shingo Miyauchi, Kerrie Barry, Alicia Clum, Anna Lipzen, Daniel Mousain, Vivian Ng, Ran Wang, Yucheng Dai, Bernard Henrissat, Igor V. Grigoriev, Alexis Guerin‐Laguette, Fuqiang Yu, Francis M. Martin New Phytologist 235 (1), 306-319, 2022-04-28

...A high copy number of genes coding for small secreted LysM proteins and <jats:italic>Lactarius</jats:italic>‐specific lectins were detected, which may be linked to host specificity....

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横田 洸成, 冨松 聖史, 小南 春祐, 梶浦 僚太, 田中 翔大, 尾花 理徳, 岡田 欣晃, 藤尾 慈 日本薬理学会年会要旨集 96 (0), 3-B-O09-3-, 2022

...Double TG mice (DTG mice) were generated by crossing CD11b-DTR TG mice with LysM-Cre mice that express Cre recombinase preferentially in monocytes/macrophages....

DOI Web Site

Jan Ackermann, Lilli Arndt, Michaela Kirstein, Constance Hobusch, Georg Brinker, Nora Klöting, Julia Braune, Martin Gericke The Journal of Immunology 207 (12), 3081-3089, 2021-12-15

...In this study, we examined the metabolic and inflammatory phenotype of C57BL/6J mice (IIl4ra) with LysM-dependent knockout (IIl4raΔmyel) of the IL-4 receptor α-chain (IL-4Rα), the mandatory signaling component...

DOI PDF 被引用文献1件

Fernanda Raya-Tonetti, Melisa Müller, Jacinto Sacur, Haruki Kitazawa, Julio Villena, Maria Guadalupe Vizoso-Pinto Scientific Reports 11 (1), 1-, 2021-11-04

...<jats:title>Abstract</jats:title><jats:p>We characterized two LysM domains of <jats:italic>Limosilactobacillus fermentum</jats:italic>, belonging to proteins Acglu (GenBank: KPH22907.1) and Pgb (GenBank...

DOI PDF Web Site 被引用文献3件

Moira Giovannoni, Damiano Lironi, Lucia Marti, Chiara Paparella, Valeria Vecchi, Andrea A. Gust, Giulia De Lorenzo, Thorsten Nürnberger, Simone Ferrari Plant, Cell & Environment 44 (12), 3775-3792, 2021-09-30

...<jats:title>Abstract</jats:title><jats:p>In <jats:italic>Arabidopsis thaliana</jats:italic>, perception of chitin from fungal cell walls is mediated by three LysM‐containing Receptor‐Like Kinases (LYKs...

DOI Web Site Web Site 被引用文献1件

Diego Rebaque, Irene del Hierro, Gemma López, Laura Bacete, Francisco Vilaplana, Pietro Dallabernardina, Fabian Pfrengle, Lucía Jordá, Andrea Sánchez‐Vallet, Rosa Pérez, Frédéric Brunner, Antonio Molina, Hugo Mélida The Plant Journal 106 (3), 601-615, 2021-03-22

...Cross‐elicitation experiments between MLG43 and the carbohydrate MAMP chitohexaose [β‐1,4‐<jats:sc>d</jats:sc>‐(GlcNAc)<jats:sub>6</jats:sub>], which is also perceived by these LysM PRRs, indicated that...

DOI Web Site Web Site 被引用文献1件

Keiichiro Kumamoto, Takashi Tasaki, Koji Ohnishi, Michihiko Shibata, Shohei Shimajiri, Masaru Harada, Yoshihiro Komohara, Toshiyuki Nakayama Frontiers in Oncology 11 2021-03-19

...The expression on CD169 in LySMs is a predictor of a favorable clinical course in patients with gastric cancer, and might be useful for evaluating anti-cancer immune responses.</jats:p>...

DOI Web Site 被引用文献1件

Shu-Ping Hu, Jun-Jiao Li, Nikhilesh Dhar, Jun-Peng Li, Jie-Yin Chen, Wei Jian, Xiao-Feng Dai, Xing-Yong Yang International Journal of Molecular Sciences 22 (6), 3114-, 2021-03-18

...In contrast, fungal LysM blocks chitin sensing or signaling to inhibit chitin-induced host immunity....

DOI Web Site 被引用文献1件

Longmin Chen, Jing Zhang, Yuan Zou, Faxi Wang, Jingyi Li, Fei Sun, Xi Luo, Meng Zhang, Yanchao Guo, Qilin Yu, Ping Yang, Qing Zhou, Zhishui Chen, Huilan Zhang, Quan Gong, Jiajun Zhao, Decio L. Eizirik, Zhiguang Zhou, Fei Xiong, Shu Zhang, Cong-Yi Wang Cell Death & Differentiation 28 (6), 1880-1899, 2021-01-18

...Herein we found that myeloid-specific knockout of <jats:italic>Kdm2a</jats:italic> (<jats:italic>LysM-</jats:italic>Cre-<jats:italic>Kdm2a</jats:italic><jats:sup>f/f</jats:sup>, <jats:italic>Kdm2a</jats...

DOI PDF Web Site 被引用文献2件

Yuyi Chen, Qiudong Yang, Chunhua Lv, Yue Chen, Wenhua Zhao, Wenlei Li, Hongyu Chen, Hua Wang, Wen Sun, Hua Yuan Cell Proliferation 54 (2), 2020-12-31

...We further used Lysm‐Cre/Rosa<jats:sup>nTnG</jats:sup> mouse to trace the changes of Lysm‐Cre<jats:sup>+</jats:sup> osteoclast precursors in ligature‐induced periodontitis with or without MCC950 treatment...

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Hironori Hara, Sonoko Maemura, Takayuki Fujiwara, Norifumi Takeda, Satoshi Ishii, Hiroki Yagi, Takaaki Suzuki, Mutsuo Harada, Haruhiro Toko, Tsubasa Kanaya, Hideaki Ijichi, Harold L. Moses, Eiki Takimoto, Hiroyuki Morita, Hiroshi Akazawa, Issei Komuro PLOS ONE 15 (11), e0239908-, 2020-11-11

...of<jats:italic>Fbn1</jats:italic><jats:sup><jats:italic>C1039G/+</jats:italic></jats:sup>MFS mice (<jats:italic>Fbn1</jats:italic><jats:sup><jats:italic>C1039G/+</jats:italic></jats:sup>;<jats:italic>LysM-Cre...

DOI Web Site 参考文献34件

Chuieng-Yi Lu, Katherine B. Santosa, Albina Jablonka-Shariff, Bianca Vannucci, Anja Fuchs, Isaiah Turnbull, Deng Pan, Matthew D. Wood, Alison K. Snyder-Warwick The Journal of Neuroscience 40 (50), 9602-9616, 2020-11-06

...Mice with Vegf-A conditionally knocked out in macrophages (<jats:italic>Vegf-A<jats:sup>fl/fl</jats:sup>; LysM<jats:sup>Cre</jats:sup></jats:italic>mice) demonstrated a more prolonged detrimental effect...

DOI Web Site 被引用文献1件

Shuya Zhang, Huan Liu, Meimei Yin, Xiuying Pei, Angelika Hausser, Eri Ishikawa, Sho Yamasaki, Zheng Gen Jin Hepatology 72 (5), 1717-1734, 2020-09-28

...</jats:sup>) mice, and we found that both <jats:italic toggle="yes">Prkd3−/− </jats:italic> mice and <jats:italic toggle="yes">Prkd3∆LysM...

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Suzuki Maruya, Numazaki Ryota, Nakagawa Tomomi, Shibuya Naoto, Kaku Hanae Ｐｌａｎｔ　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ 37 (3), 359-362, 2020-09-25

...These results indicated that such a subtle difference in the cytoplasmic domain of LysM-RLKs could determine the direction of host responses from defense to symbiosis....

DOI Web Site Web Site 参考文献14件

Zoltan Bozsoki, Kira Gysel, Simon B. Hansen, Damiano Lironi, Christina Krönauer, Feng Feng, Noor de Jong, Maria Vinther, Manoj Kamble, Mikkel B. Thygesen, Ebbe Engholm, Christian Kofoed, Sébastien Fort, John T. Sullivan, Clive W. Ronson, Knud J. Jensen, Mickaël Blaise, Giles Oldroyd, Jens Stougaard, Kasper R. Andersen, Simona Radutoiu Science 369 (6504), 663-670, 2020-08-07

<jats:title>Switching perception of friend and foe</jats:title> <jats:p> Lysine motif receptors in plants perceive glycans that signal the presence of pathogenic or symbiotic …

DOI Web Site Web Site 被引用文献2件

Daichi Shirakawa, Takura Wakinaka, Jun Watanabe Bioscience, Biotechnology, and Biochemistry 84 (8), 1724-1735, 2020-08-02

...Functional analysis of truncated CseA derivatives revealed that the LysM domains play an important role in efficient peptidoglycan degradation and cell separation....

DOI PDF 被引用文献1件

Jaslyn E. M. M. Wong, Kira Gysel, Thea G. Birkefeldt, Maria Vinther, Artur Muszyński, Parastoo Azadi, Nick S. Laursen, John T. Sullivan, Clive W. Ronson, Jens Stougaard, Kasper R. Andersen Nature Communications 11 (1), 3797-, 2020-07-30

...EPR3 forms a compact structure built of three putative carbohydrate-binding modules (M1, M2 and LysM3)....

DOI PDF Web Site 被引用文献1件

Tomoya Takashima, Ryo Sunagawa, Keiko Uechi, Toki Taira International Journal of Biological Macromolecules 154 1295-1302, 2020-07

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Andrea Sánchez-Vallet, Hui Tian, Luis Rodriguez-Moreno, Dirk-Jan Valkenburg, Raspudin Saleem-Batcha, Stephan Wawra, Anja Kombrink, Leonie Verhage, Ronnie de Jonge, H. Peter van Esse, Alga Zuccaro, Daniel Croll, Jeroen R. Mesters, Bart P. H. J. Thomma PLOS Pathogens 16 (6), e1008652-, 2020-06-23

DOI Web Site 被引用文献1件

Asuka Yasueda, Hisako Kayama, Michiko Murohashi, Junichi Nishimura, Koji Wakame, Ken-ichi Komatsu, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Mamoru Uemura, Chu Matsuda, Toru Kitagawa, Kiyoshi Takeda, Toshinori Ito, Yuichiro Doki, Hidetoshi Eguchi, Shigeomi Shimizu, Tsunekazu Mizushima Scientific Reports 10 (1), 9972-, 2020-06-19

...However, these alterations were not induced in <jats:italic>LysM-cre</jats:italic>; <jats:italic>Atg7</jats:italic><jats:sup><jats:italic>f/f</jats:italic></jats:sup> mice....

DOI PDF Web Site 被引用文献1件 参考文献60件

Geir Mathiesen, Lise Øverland, Katarzyna Kuczkowska, Vincent G. H. Eijsink Scientific Reports 10 (1), 2020-06-15

...The anchors tested were a lipoprotein anchor and two cell wall anchors, one non-covalent (LysM domain) and one covalent (sortase-based anchoring using the LPXTG motif)....

DOI PDF Web Site 被引用文献1件

Ikeda, Yasumasa, Watanabe, Hiroaki, Shiuchi, Tetsuya, Hamano, Hirofumi, Horinouchi, Yuya, Imanishi, Masaki, Goda, Mitsuhiro, Zamami, Yoshito, Takechi, Kenshi, Izawa-Ishizawa, Yuki, Miyamoto, Licht, Ishizawa, Keisuke, Aihara, Ken-ichi, Tsuchiya, Koichiro, Tamaki, Toshiaki Diabetologia 63 (8), 1588-1602, 2020-05-19

...Methods Conditional macrophage-specific H-ferritin knockout (LysM-Cre FthKO) mice were used and divided into 4 groups; Wild-type (WT) and LysM-Cre FthKO mice with normal diet (ND), and WT and LysM-Cre...

DOI 機関リポジトリ PDF ほか1件 被引用文献1件 参考文献46件

Cécilia Cheval, Sebastian Samwald, Matthew G. Johnston, Jeroen de Keijzer, Andrew Breakspear, Xiaokun Liu, Annalisa Bellandi, Yasuhiro Kadota, Cyril Zipfel, Christine Faulkner Proceedings of the National Academy of Sciences 117 (17), 9621-9629, 2020-04-13

...Focusing on chitin signaling, we found that responses in the plasmodesmal PM require the LysM receptor kinases LYK4 and LYK5 in addition to LYM2....

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Qiming Chen, Chaohua Dong, Xiaohong Sun, Yugang Zhang, Hongyi Dai, Suhua Bai BMC Plant Biology 20 (1), 146-, 2020-04-08

...<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Lysin motif (LysM)-containing proteins are involved in the recognition of fungal and bacterial pathogens....

DOI PDF Web Site 被引用文献2件

Abdelrahman Y. Fouda, Zhimin Xu, S. Priya Narayanan, R. William Caldwell, Ruth B. Caldwell Investigative Opthalmology & Visual Science 61 (3), 51-, 2020-03-30

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Fabienne Maillet, Joëlle Fournier, Hajeewaka C. Mendis, Million Tadege, Jiangqi Wen, Pascal Ratet, Kirankumar S. Mysore, Clare Gough, Kathryn M. Jones The Plant Journal 102 (2), 311-326, 2020-01-11

<jats:title>Summary</jats:title><jats:p>The formation of nitrogen‐fixing nodules on legume hosts is a finely tuned process involving many components of both symbiotic partners. Production of the …

DOI Web Site Web Site ほか1件 被引用文献1件

Tomonori Shinya, Naoto Shibuya, Hanae Kaku Methods in Molecular Biology 401-412, 2020

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Bongjin Shin, Justine Kupferman, Ewoud Schmidt, Franck Polleux, Anne M Delany, Sun-Kyeong Lee Journal of Bone and Mineral Research 35 (4), 789-800, 2019-12-27

...The bone phenotype of mice specifically lacking Srgap2 in the myeloid lineage (Srgap2 f/f:LysM-Cre; Srgap2 conditional knockout [cKO]) was investigated using histomorphometric analysis, in vitro cultures...

DOI PDF Web Site ほか2件 被引用文献1件

Jiangman He, Chi Zhang, Huiling Dai, Huan Liu, Xiaowei Zhang, Jun Yang, Xi Chen, Yayun Zhu, Dapeng Wang, Xiaofeng Qi, Weichao Li, Zhihui Wang, Guoyong An, Nan Yu, Zuhua He, Yong-Fei Wang, Youli Xiao, Peng Zhang, Ertao Wang Molecular Plant 12 (12), 1561-1576, 2019-12

DOI Web Site Web Site 被引用文献7件

Tian Zeng, Luis Rodriguez‐Moreno, Artem Mansurkhodzaev, Peng Wang, Willy van den Berg, Virginie Gasciolli, Sylvain Cottaz, Sébastien Fort, Bart P. H. J. Thomma, Jean‐Jacques Bono, Ton Bisseling, Erik Limpens New Phytologist 225 (1), 448-460, 2019-11-23

...for LysM effectors in both symbiotic and pathogenic fungi....

DOI Web Site Web Site ほか2件 被引用文献2件

Chan Hee Lee, Sung Hoon Shin, Gil Myoung Kang, Seongjun Kim, Jiye Kim, Rina Yu, Min-Seon Kim Journal of Neuroinflammation 16 (1), 221-, 2019-11-14

...LysM<jats:sup>GFP</jats:sup> cells appeared in the hypothalamic area from the late embryonic period....

DOI PDF Web Site 被引用文献1件

Vermassen, Talon, Andant, Provot, Desvaux, Leroy Microorganisms 7 (11), 559-, 2019-11-12

...Sle1, which is encoded by chromosomal gene and composed of three anchoring LysM domains and a C-terminal CHAP (cysteine, histidine-dependent amidohydrolase/peptidase) domain, was one of the most active...

DOI Web Site 被引用文献1件

Mizuho Kittaka, Tetsuya Yoshimoto, Collin Schlosser, Robert Rottapel, Mikihito Kajiya, Hidemi Kurihara, Ernst J Reichenberger, Yasuyoshi Ueki Journal of Bone and Mineral Research 35 (2), 382-395, 2019-10-15

...Conditional knockout of SH3BP2 and SYK in myeloid lineage cells with LysM-Cre mice recapitulated the reduced bone loss without affecting both inflammatory cytokine expression and osteoclast induction,...

DOI PDF Web Site ほか1件 被引用文献3件

Helena Volk, Kristina Marton, Marko Flajšman, Sebastjan Radišek, Hui Tian, Ingo Hein, Črtomir Podlipnik, Bart P. H. J. Thomma, Katarina Košmelj, Branka Javornik, Sabina Berne Molecular Plant-Microbe Interactions® 32 (10), 1378-1390, 2019-10

...The recognition of released chitin oligomers via lysin motif (LysM)-containing immune host receptors results in the activation of defense signaling pathways....

DOI Web Site 被引用文献2件

Yordan J. Romero-Contreras, Claudia A. Ramírez-Valdespino, Paulina Guzmán-Guzmán, Juan Ignacio Macías-Segoviano, Julio César Villagómez-Castro, Vianey Olmedo-Monfil Frontiers in Microbiology 10 2019-09-25

DOI Web Site 被引用文献1件

Yoshitake Desaki, Shohei Takahashi, Kenta Sato, Kanako Maeda, Saki Matsui, Ikuya Yoshimi, Takaki Miura, Jun-Ichi Jumonji, Jun Takeda, Kohei Yashima, Masaki Kohari, Takayoshi Suenaga, Hayato Terada, Tomoko Narisawa, Takeo Shimizu, Emi Yumoto, Koji Miyamoto, Mari Narusaka, Yoshihiro Narusaka, Hanae Kaku, Naoto Shibuya Plant and Cell Physiology 60 (11), 2573-2583, 2019-08-01

...<jats:title>Abstract</jats:title> <jats:p>Lysin motif (LysM) receptor-like kinase CERK1 is a co-receptor essential for plant immune responses against carbohydrate microbe-associated molecular...

DOI PDF PDF 被引用文献4件 参考文献63件

Jaslyn E. M. M. Wong, Marcin Nadzieja, Lene H. Madsen, Christoph A. Bücherl, Svend Dam, Niels N. Sandal, Daniel Couto, Paul Derbyshire, Mette Uldum-Berentsen, Sina Schroeder, Veit Schwämmle, Fábio C. S. Nogueira, Mette H. Asmussen, Søren Thirup, Simona Radutoiu, Mickaël Blaise, Kasper R. Andersen, Frank L. H. Menke, Cyril Zipfel, Jens Stougaard Proceedings of the National Academy of Sciences 116 (28), 14339-14348, 2019-06-25

<jats:title>Significance</jats:title> <jats:p> Legume receptors perceive Nod factor signal molecules at the plasma membrane of epidermal cells and initiate a signal …

DOI Web Site Web Site 被引用文献1件

Elisa Nent, Chihiro Nozaki, Anne-Caroline Schmöle, David Otte, Andreas Zimmer Scientific Reports 9 (1), 2019-05-16

...This behavioral pain phenotype was accompanied by an increased staining of microglia in the dorsal horn of the spinal cord, as evidenced by an enhanced Iba 1 expression [CB2KO, p = 0.0175; CB2-LysM, p ...

DOI PDF Web Site 被引用文献1件

Fredrik Dölfors, Louise Holmquist, Christina Dixelius, Georgios Tzelepis Molecular Genetics and Genomics 294 (5), 1211-1218, 2019-05-10

DOI PDF Web Site 被引用文献1件

Cecilia Cheval, Matthew Johnston, Sebastian Samwald, Xiaokun Liu, Annalisa Bellandi, Andrew Breakspear, Yasuhiro Kadota, Cyril Zipfel, Christine Faulkner 2019-04-17

...We found that the plasmodesmal PM employs a receptor complex composed of the LysM receptors LYM2 and LYK4 which respectively change their location and interactions in response to chitin....

DOI Web Site 参考文献57件

Stefanie Finger, Maike Knorr, Michael Molitor, Rebecca Schüler, Venkata Garlapati, Ari Waisman, Moritz Brandt, Thomas Münzel, Tobias Bopp, Sabine Kossmann, Susanne Karbach, Philip Wenzel Cardiovascular Research 115 (13), 1907-1917, 2019-04-05

...Mortality after MI was significantly increased in LysM+ cell-depleted mice within 28 days post-MI....

DOI PDF PDF 被引用文献1件

Talita L. C. Cezar, Renata M. Martinez, Camila da Rocha, Cristina P. B. Melo, David L. Vale, Sergio M. Borghi, Victor Fattori, Josiane A. Vignoli, Doumit Camilios-Neto, Marcela M. Baracat, Sandra R. Georgetti, Waldiceu A. Verri, Rubia Casagrande Scientific Reports 9 (1), 3062-, 2019-02-28

...The treatment with MaR1 (0.1–10 ng/mice at −10 min relative to the UVB irradiation protocol) reduced UVB-induced skin edema, neutrophil recruitment (MPO; myeloperoxidase activity, and migration of LysM-eGFP...

DOI PDF Web Site 被引用文献4件

Suzanne ABM Aarts, Tom TP Seijkens, Pascal JH Kusters, Claudia M van Tiel, Myrthe E Reiche, Myrthe den Toom, Linda Beckers, Cindy PAA van Roomen, Menno PJ de Winther, Gijs Kooij, Esther Lutgens The Journal of Pathology 247 (4), 471-480, 2019-01-30

...As CD40–TRAF6 interactions predominantly occur in macrophages, we subjected <jats:italic>CD40</jats:italic><jats:sup><jats:italic>flfl</jats:italic></jats:sup><jats:italic>LysM</jats:italic><jats:sup><...

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Federico Lopez-Moya, Marta Suarez-Fernandez, Luis Lopez-Llorca International Journal of Molecular Sciences 20 (2), 332-, 2019-01-15

...LysM effectors shield chitin and protect fungal cell walls from plant chitinases....

DOI Web Site 被引用文献1件

Xiaojing Wang, Marcelle de Carvalho Ribeiro, Arvin Iracheta‐Vellve, Patrick Lowe, Aditya Ambade, Abhishek Satishchandran, Terence Bukong, Donna Catalano, Karen Kodys, Gyongyi Szabo Hepatology 69 (2), 545-563, 2019-01-04

...LysM<jats:sup>Cre</jats:sup> HIF<jats:sup>dPA</jats:sup>fl/fl mice, which have HIF‐1α levels stabilized in macrophages, showed higher steatosis and liver inflammation compared with HIF<jats:sup>dPA</jats...

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Takeya Hiroto, Ohnishi Koji, Shiota Takuya, Saito Yoichi, Fujiwara Yukio, Yagi Taisuke, Kiyozumi Yuki, Baba Yoshifumi, Yoshida Naoya, Asano Kenichi, Tanaka Masato, Baba Hideo, Komohara Yoshihiro Ｊｏｕｒｎａｌ　ｏｆ　Ｃｌｉｎｉｃａｌ　ａｎｄ　Ｅｘｐｅｒｉｍｅｎｔａｌ　Ｈｅｍａｔｏｐａｔｈｏｌｏｇｙ 59 (3), 112-118, 2019

...High Maf expression was seen in the nucleus of macrophages in the gastrointestinal tract and lymph node sinus macrophages (LySMs)....

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Takeyuki Kurosawa, Shion Miyoshi, Soh Yamazaki, Takashi Nishina, Tetuo Mikami, Akira Oikawa, Sakae Homma, Hiroyasu Nakano Genes to Cells 24 (2), 112-125, 2018-12-18

...Transfer of wild‐type BM cells into <jats:italic>LysM‐DTR</jats:italic> mice accelerated the regeneration of AEC2s along with the up‐regulation of several growth factors....

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Hiroto Takeya, Takuya Shiota, Taisuke Yagi, Koji Ohnishi, Yoshifumi Baba, Yuko Miyasato, Yuki Kiyozumi, Naoya Yoshida, Motohiro Takeya, Hideo Baba, Yoshihiro Komohara Pathology International 68 (12), 685-693, 2018-12

...Higher CD169 expression in LySMs was significantly associated with longer cancer‐specific survival (CSS)....

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Katja Zschiebsch, Caroline Fischer, Annett Wilken‐Schmitz, Gerd Geisslinger, Keith Channon, Katrin Watschinger, Irmgard Tegeder Journal of Cellular and Molecular Medicine 23 (2), 985-1000, 2018-11-18

...Unexpectedly, knockout or overexpression in myeloid cells had no effect on nociceptive behaviour, but LysM‐driven <jats:styled-content style="fixed-case">GCH</jats:styled-content>1 knockout reduced, and...

DOI Web Site Web Site 被引用文献1件

Yoshitake Desaki, Masaki Kohari, Naoto Shibuya, Hanae Kaku Journal of General Plant Pathology 85 (1), 1-11, 2018-11-08

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Ekaterina Gubaeva, Airat Gubaev, Rebecca L. J. Melcher, Stefan Cord-Landwehr, Ratna Singh, Nour Eddine El Gueddari, Bruno M. Moerschbacher Molecular Plant-Microbe Interactions® 31 (11), 1145-1153, 2018-11

...a long but off-set chitin-binding groove and are, thus, dimerized by one chitin or chitosan molecule, sharing a central GlcNAc unit with which both LysM domains interact....

DOI Web Site 被引用文献2件

Kent Sakai, Shuichi Nagashima, Tetsuji Wakabayashi, Bayasgalan Tumenbayar, Hiroko Hayakawa, Morisada Hayakawa, Tadayoshi Karasawa, Ken Ohashi, Hisataka Yamazaki, Akihito Takei, Shoko Takei, Daisuke Yamamuro, Manabu Takahashi, Hiroaki Yagyu, Jun-ichi Osuga, Masafumi Takahashi, Shin-ichi Tominaga, Shun Ishibashi Arteriosclerosis, Thrombosis, and Vascular Biology 38 (11), 2590-2600, 2018-11

...>m−</jats:italic> </jats:sup> <jats:sup> <jats:italic>/m</jats:italic> </jats:sup> <jats:sup>−</jats:sup> ) using LysM...

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Luis Buendia, Ariane Girardin, Tongming Wang, Ludovic Cottret, Benoit Lefebvre Frontiers in Plant Science 9 1531-, 2018-10-24

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Carlos W. Wanderley, David F. Colón, João Paulo M. Luiz, Francisco F. Oliveira, Paula R. Viacava, Caio A. Leite, Janaina A. Pereira, Camila M. Silva, Cassia R. Silva, Rangel L. Silva, Cesar A. Speck-Hernandez, José M. Mota, José C. Alves-Filho, Roberto C. Lima-Junior, Thiago M. Cunha, Fernando Q. Cunha Cancer Research 78 (20), 5891-5900, 2018-10-15

...In mice selectively lacking TLR4 on myeloid cells, for example, macrophages (LysM-Cre+/−/TLR4fl/fl), the antitumor effect of paclitaxel was attenuated....

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Dehua Liao, Xun Sun, Ning Wang, Fengming Song, Yan Liang Frontiers in Plant Science 9 1004-, 2018-07-11

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Clare Gough, Ludovic Cottret, Benoit Lefebvre, Jean-Jacques Bono Frontiers in Plant Science 9 923-, 2018-07-04

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Eiichi Murakami, Jeryl Cheng, Kira Gysel, Zoltan Bozsoki, Yasuyuki Kawaharada, Christian Toftegaard Hjuler, Kasper Kildegaard Sørensen, Ke Tao, Simon Kelly, Francesco Venice, Andrea Genre, Mikkel Boas Thygesen, Noor de Jong, Maria Vinther, Dorthe Bødker Jensen, Knud Jørgen Jensen, Michael Blaise, Lene Heegaard Madsen, Kasper Røjkjær Andersen, Jens Stougaard, Simona Radutoiu eLife 7 e33506-, 2018-06-29

...Here we show that an epidermal LysM receptor (NFRe), ensures robust signalling in L. japonicus....

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Girija Goyal, Karrie Wong, Christopher J. Nirschl, Nicholas Souders, Donna Neuberg, Niroshana Anandasabapathy, Glenn Dranoff Cancer Immunology Research 6 (6), 723-732, 2018-05-31

...Mice harboring a deletion of pparg in lysozyme M (LysM)-expressing myeloid cells (KO) showed a decreased ratio of CD8+ T effectors to Tregs and impaired tumor rejection with GVAX....

DOI PDF 被引用文献1件

Zhiyuan Lv, Yan Huang, Bi Ma, Zhonghuai Xiang, Ningjia He Plant Cell Reports 37 (8), 1101-1112, 2018-05-30

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Hongmei Li, Sang Jun Han, Mihwa Kim, Ahyeon Cho, Yewoon Choi, Vivette D’Agati, H. Thomas Lee American Journal of Physiology-Renal Physiology 314 (5), F809-F819, 2018-05-01

...plays a critical role in exacerbating ischemic AKI by utilizing mice lacking PAD4 in renal proximal tubules (PAD4<jats:sup>ff</jats:sup>PEPCK Cre mice) or in granulocytes (PAD4<jats:sup>ff</jats:sup>LysM...

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Zhe Zhou, Yi Tian, Peihua Cong, Yanmin Zhu Plant Science 269 56-65, 2018-04

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Yan Zhang, Nidhi Rohatgi, Deborah J Veis, Joel Schilling, Steven L Teitelbaum, Wei Zou Journal of Bone and Mineral Research 33 (6), 1114-1125, 2018-03-08

...Consequently, bone mass of PGC1βLysM mice is double that of wild type. Mitochondrial biogenesis and function are diminished in PGC1βLysM osteoclasts....

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Takanori Komada, Hyunjae Chung, Arthur Lau, Jaye M. Platnich, Paul L. Beck, Hallgrimur Benediktsson, Henry J. Duff, Craig N. Jenne, Daniel A. Muruve Journal of the American Society of Nephrology 29 (4), 1165-1181, 2018-02-09

...Intravital microscopy of the kidney in <jats:italic toggle="yes">LysM(gfp/gfp) </jats:italic> mice 5–6 days after UUO demonstrated the significant recruitment of GFP<jats:sup...

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Katsuhiko Shinomiya, Mayumi Ueta, Shigeru Kinoshita Scientific Reports 8 (1), 1483-, 2018-01-24

...In the observation of LysM-eGFP<jats:sup>(+/−)</jats:sup> mice tissues, postsurgical infiltration of green fluorescent neutrophils was observed in the ocular surface tissues....

DOI PDF Web Site 被引用文献2件

Lynda Zeboudj, Andréas Giraud, Lea Guyonnet, Yujiao Zhang, Ludivine Laurans, Bruno Esposito, Jose Vilar, Anna Chipont, Nikolina Papac-Milicevic, Christoph J. Binder, Alain Tedgui, Ziad Mallat, Pierre-Louis Tharaux, Hafid Ait-Oufella Arteriosclerosis, Thrombosis, and Vascular Biology 38 (1), 114-119, 2018-01

...lesion size was significantly reduced in irradiated <jats:italic>Ldlr</jats:italic> <jats:sup>−/−</jats:sup> mice reconstituted with <jats:italic>LysM...

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Huo Mingyu, Zhang Hongsong, Tian Danyang, Lau Chi Wai, Wu Yalan, Chawla Ajay, Huang Yu, Tian Xiao Yu 日本薬理学会年会要旨集 WCP2018 (0), OR1-3-, 2018

...</p><p>Methods</p><p>We use the Bmal1 FloxP/FloxP (Bmal1MWT) as control and Bmal1 FloxP/FloxP, LysM Cre/+ (Bmal1MKO) as myeloid specific Bmal1 deficient mice housed under 12 hour light and dark cycle at...

DOI Web Site

Irina Leppyanen, Vlada Shakhnazarova, Oksana Shtark, Nadezhda Vishnevskaya, Igor Tikhonovich, Elena Dolgikh International Journal of Molecular Sciences 19 (1), 8-, 2017-12-21

...In model plants Arabidopsis thaliana and Oryza sativa LysM-receptor like kinases (LysM-RLK) AtCERK1 and OsCERK1 (chitin elicitor receptor kinase 1) were shown to be involved in response to CO signals....

DOI Web Site 被引用文献1件

Hugo Mélida, Sara Sopeña‐Torres, Laura Bacete, María Garrido‐Arandia, Lucía Jordá, Gemma López, Antonio Muñoz‐Barrios, Luis F. Pacios, Antonio Molina The Plant Journal 93 (1), 34-49, 2017-12-02

...Recognition of 1,3‐β‐<jats:sc>d</jats:sc>‐(Glc)<jats:sub>6</jats:sub> was impaired in <jats:italic>cerk1</jats:italic> but not in mutants defective in either each of the LysM <jats:styled-content style...

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Takayuki Ohnuma, Toki Taira, Naoyuki Umemoto, Yoshihito Kitaoku, Morten Sørlie, Tomoyuki Numata, Tamo Fukamizo Biochemical and Biophysical Research Communications 494 (3-4), 736-741, 2017-12

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Mary Y. Chang, Inkyung Kang, Michael Gale, Anne M. Manicone, Michael G. Kinsella, Kathleen R. Braun, Tara Wigmosta, William C. Parks, William A. Altemeier, Thomas N. Wight, Charles W. Frevert American Journal of Physiology-Lung Cellular and Molecular Physiology 313 (6), L1069-L1086, 2017-12-01

...poly(I:C)-treated LysM/ Vcan<jats:sup>−/−</jats:sup>mice compared with control mice....

DOI Web Site 被引用文献3件

Yoshitake Desaki, Yusuke Kouzai, Yusuke Ninomiya, Ryosuke Iwase, Yumi Shimizu, Keito Seko, Antonio Molinaro, Eiichi Minami, Naoto Shibuya, Hanae Kaku, Yoko Nishizawa New Phytologist 217 (3), 1042-1049, 2017-11-30

...Os<jats:styled-content style="fixed-case">CERK</jats:styled-content>1 is a multifunctional <jats:styled-content style="fixed-case">RLK</jats:styled-content> in rice that contains lysin motifs (LysMs) and...

DOI Web Site Web Site ほか1件 被引用文献7件 参考文献50件

Yoshitake Desaki, Kana Miyata, Maruya Suzuki, Naoto Shibuya, Hanae Kaku Innate Immunity 24 (2), 92-100, 2017-11-06

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Zarha Vermeulen, Anne-Sophie Hervent, Lindsey Dugaucquier, Leni Vandekerckhove, Miche Rombouts, Matthias Beyens, Dorien M. Schrijvers, Guido R. Y. De Meyer, Stuart Maudsley, Gilles W. De Keulenaer, Vincent F. M. Segers American Journal of Physiology-Heart and Circulatory Physiology 313 (5), H934-H945, 2017-11-01

...Furthermore, mice with myeloid-specific deletion of the ErbB4 gene ( ErbB4<jats:sup>F/F</jats:sup>LysM-Cre<jats:sup>+/−</jats:sup>) showed an intensified myocardial fibrotic response to ANG II....

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Zhaoyu Liu, Huaiping Zhu, Xiaoyan Dai, Cheng Wang, Ye Ding, Ping Song, Ming-Hui Zou Circulation Research 121 (9), 1047-1057, 2017-10-13

...To further investigate the role of macrophage LKB1 in vivo, ApoE <jats:sup>−/−</jats:sup> LKB1 <jats:sup>fl/fl</jats:sup> LysM <jats...

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Simon Kelly, Simona Radutoiu, Jens Stougaard Current Opinion in Plant Biology 39 152-158, 2017-10

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Jun Xu, Guilin Wang, Jing Wang, Yongqing Li, Liangliang Tian, Xinyu Wang, Wangzhen Guo BMC Plant Biology 17 (1), 148-, 2017-09-04

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Qian Wu, Yuanyuan Shen, Yunlong Tao, Jiayu Wei, Hao Wang, Peng An, Zhuzhen Zhang, Hong Gao, Tianhua Zhou, Fudi Wang, Junxia Min Cell Discovery 3 (1), 2017-08-15

...italic>−/−</jats:italic></jats:sup>), and macrophage-specific<jats:italic>ferroportin-1</jats:italic>(<jats:italic>Fpn1</jats:italic><jats:sup><jats:italic>fl/fl</jats:italic></jats:sup>;<jats:italic>LysM-Cre...

DOI PDF Web Site ほか1件 被引用文献1件

Ryan N. C. Buensuceso, Martin Daniel-Ivad, Sara L. N. Kilmury, Tiffany L. Leighton, Hanjeong Harvey, P. Lynne Howell, Lori L. Burrows Journal of Bacteriology 199 (16), 2017-08-15

...Both cytoplasmic and periplasmic domains of FimV were important for its cAMP-dependent and -independent roles, while its septal peptidoglycan-targeting LysM motif was required only for twitching motility...

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Zbigniew Zasłona, Sarah Case, James O. Early, Stephen J. Lalor, Rachel M. McLoughlin, Anne M. Curtis, Luke A. J. O’Neill American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (6), L855-L860, 2017-06-01

...We used mice lacking BMAL1 in myeloid cells (BMAL1-LysM<jats:sup>−/−</jats:sup>) to determine the role of BMAL1 in allergic asthma....

DOI Web Site 被引用文献4件

Can Martin Sag, Moritz Schnelle, Juqian Zhang, Colin E. Murdoch, Sabine Kossmann, Andrea Protti, Celio X.C. Santos, Greta Sawyer, Xiaohong Zhang, Heloise Mongue-Din, Daniel A. Richards, Alison C. Brewer, Oleksandra Prysyazhna, Lars S. Maier, Philip Wenzel, Philip J. Eaton, Ajay M. Shah Circulation 135 (22), 2163-2177, 2017-05-30

...</jats:p> </jats:sec> <jats:sec> <jats:title>Methods:</jats:title> <jats:p>We generated a novel mouse model with a floxed Nox2 gene and used Tie2-Cre, LysM Cre...

DOI Web Site 被引用文献3件

Livia A. Alves, Erika N. Harth‐Chu, Thais H. Palma, Rafael N. Stipp, Flávia S. Mariano, José F. Höfling, Jacqueline Abranches, Renata O. Mattos‐Graner Molecular Oral Microbiology 32 (5), 419-431, 2017-05-25

...italic>vicK</jats:italic><jats:sub><jats:italic>Sm</jats:italic></jats:sub><jats:italic>‐</jats:italic>downstream genes (<jats:italic>smaA</jats:italic>,<jats:italic> smu.2146c</jats:italic>,<jats:italic> lysM...

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Jan Erwig, Hassan Ghareeb, Michaela Kopischke, Ronja Hacke, Alexandra Matei, Elena Petutschnig, Volker Lipka New Phytologist 215 (1), 382-396, 2017-05-17

...To investigate the ligand‐induced spatial dynamics of chitin receptor components, we studied the subcellular behaviour of two <jats:italic>Arabidopsis thaliana</jats:italic> LysM‐RLKs involved in chitin...

DOI Web Site Web Site ほか2件 被引用文献4件

Qian Cong, Hao Jia, Ping Li, Shoutao Qiu, James Yeh, Yibin Wang, Zhen-Lin Zhang, Junping Ao, Baojie Li, Huijuan Liu Scientific Reports 7 (1), 45964-, 2017-04-06

...Here we investigated the potential roles of p38 MAPKs, which are activated by growth factors and cytokines including RANKL and BMPs, in osteoclastogenesis and bone resorption by ablating p38α MAPK in LysM...

DOI PDF Web Site ほか1件 被引用文献1件

Gennaro Carotenuto, Mireille Chabaud, Kana Miyata, Martina Capozzi, Naoya Takeda, Hanae Kaku, Naoto Shibuya, Tomomi Nakagawa, David G. Barker, Andrea Genre New Phytologist 214 (4), 1440-1446, 2017-03-29

...<jats:title>Summary</jats:title><jats:p> <jats:list list-type="bullet"> <jats:list-item><jats:p>The rice lysin‐motif (LysM) receptor‐like kinase <jats:italic>Os</jats:italic><jats:styled-content style...

DOI Web Site Web Site ほか2件 被引用文献7件 参考文献35件

Yinjing Song, Lihua Lai, Zhenlu Chong, Jia He, Yuanyuan Zhang, Yue Xue, Yiwei Xie, Songchang Chen, Ping Dong, Luoquan Chen, Zhimin Chen, Feng Dai, Xiaopeng Wan, Peng Xiao, Xuetao Cao, Yang Liu, Qingqing Wang Nature Communications 8 (1), 14654-, 2017-03-13

...When infected with VSV or influenza A virus, FBXW7 conditional knockout mice (Lysm<jats:sup>+</jats:sup>FBXW7<jats:sup>f/f</jats:sup>) show impaired antiviral immunity....

DOI PDF Web Site 被引用文献2件

KAWAHARADA, Yasuyuki, NIELSEN, Mette W., KELLY, Simon, JAMES, Euan K., ANDERSEN, Kasper R., RASMUSSEN, Sheena R., FÜCHTBAUER, Winnie, MADSEN, Lene H., HECKMANN, Anne B., RADUTOIU, Simona, STOUGAARD, Jens Nature communications 8 14534-, 2017-02-23

...In Lotus japonicus, a LysM receptor kinase, EPR3, distinguishes compatible and incompatible rhizobial exopolysaccharides at the epidermis....

機関リポジトリ

Yasuyuki Kawaharada, Mette W. Nielsen, Simon Kelly, Euan K. James, Kasper R. Andersen, Sheena R. Rasmussen, Winnie Füchtbauer, Lene H. Madsen, Anne B. Heckmann, Simona Radutoiu, Jens Stougaard Nature Communications 8 (1), 14534-, 2017-02-23

...<jats:title>Abstract</jats:title><jats:p>In <jats:italic>Lotus japonicus</jats:italic>, a LysM receptor kinase, EPR3, distinguishes compatible and incompatible rhizobial exopolysaccharides at the epidermis...

DOI PDF Web Site 被引用文献9件

Koji Shido, Deebly Chavez, Zhongwei Cao, Jane L Ko, Shahin Rafii, Bi-Sen Ding Signal Transduction and Targeted Therapy 2 (1), 16044-, 2017-02-17

.../lysM</jats:sup>)....

DOI PDF Web Site 被引用文献1件

Masaki Honda, Takayuki Takeichi, Shintaro Hashimoto, Daiki Yoshii, Kaori Isono, Shintaro Hayashida, Yuki Ohya, Hidekazu Yamamoto, Yasuhiko Sugawara, Yukihiro Inomata The Journal of Immunology 198 (4), 1718-1728, 2017-02-15

...LysM-eGFP mice were subjected to partial warm hepatic I/R. They were pretreated with an FPR1 antagonist, cyclosporine H (CsH), or formyl peptide, fMLF....

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Anja Kombrink, Hanna Rovenich, Xiaoqian Shi‐Kunne, Eduardo Rojas‐Padilla, Grardy C. M. van den Berg, Emmanouil Domazakis, Ronnie de Jonge, Dirk‐Jan Valkenburg, Andrea Sánchez‐Vallet, Michael F. Seidl, Bart P. H. J. Thomma Molecular Plant Pathology 18 (4), 596-608, 2017-02-14

...Remarkably, and in contrast with the previously studied LysM effectors of other plant pathogens, no expression of core LysM effectors was monitored <jats:italic>in planta</jats:italic> in a taxonomically...

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Ting Wang, Huiying Liu, Guan Lian, Song-Yang Zhang, Xian Wang, Changtao Jiang Mediators of Inflammation 2017 1-10, 2017

...Cellular bioenergetics analysis showed lower cellular oxygen consumption rates in the Lysm HIF1<jats:italic>α</jats:italic>lsl mice....

DOI PDF XML 被引用文献3件

Xiao-Ming Meng, Shuang Wang, Xiao-Ru Huang, Chen Yang, Jun Xiao, Yang Zhang, Ka-Fai To, David J Nikolic-Paterson, Hui-Yao Lan Cell Death & Disease 7 (12), e2495-e2495, 2016-12-01

...Fate-mapping studies in <jats:italic>LysM</jats:italic><jats:sup><jats:italic>Cre</jats:italic></jats:sup><jats:italic>Tomato</jats:italic> mice identified substantial numbers of Tomato<jats:sup>+</jats...

DOI PDF Web Site 被引用文献4件

Serra Ucer, Srividhya Iyer, Ha-Neui Kim, Li Han, Christine Rutlen, Kelly Allison, Jeff D Thostenson, Rafael de Cabo, Robert L Jilka, Charles O'Brien, Maria Almeida, Stavros C Manolagas Journal of Bone and Mineral Research 32 (3), 560-574, 2016-10-07

...CXCL12, an osteoclastogenic cytokine whose effects were abrogated in macrophages from mitoCAT;LysM-Cre mice....

DOI PDF Web Site 被引用文献1件

Paaqua Grant, Tara Maga, Anna Loshakov, Rishi Singhal, Aminah Wali, Jennifer Nwankwo, Kaitlin Baron, Diana Johnson G3 Genes|Genomes|Genetics 6 (10), 3185-3196, 2016-10-01

...and its product is part of the HOPS complex, which participates in transport and organelle fusion. red Malpighian tubule is the CG12207 gene, which encodes a protein of unknown function that includes a LysM...

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Kana Miyata, Masahiro Hayafune, Yoshihiro Kobae, Hanae Kaku, Yoko Nishizawa, Yoshiki Masuda, Naoto Shibuya, Tomomi Nakagawa Plant and Cell Physiology 57 (11), 2283-2290, 2016-08-12

DOI PDF 被引用文献4件 参考文献37件

S. R. Rasmussen, W. Füchtbauer, M. Novero, V. Volpe, N. Malkov, A. Genre, P. Bonfante, J. Stougaard, S. Radutoiu Scientific Reports 6 (1), 2016-07-20

...Here we show that divergence of <jats:italic>Lys11</jats:italic> and <jats:italic>Nfr5</jats:italic> LysM receptor kinase paralogs of <jats:italic>Lotus japonicus</jats:italic> has affected their specificity...

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Hanae Kaku, Naoto Shibuya Physiological and Molecular Plant Pathology 95 60-65, 2016-07

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Xiu-Zhen Shi, Xiao-Wu Feng, Jie-Jie Sun, Ming-Chong Yang, Jiang-Feng Lan, Xiao-Fan Zhao, Jin-Xing Wang Fish & Shellfish Immunology 54 489-498, 2016-07

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Clément Ricard, Aurélie Tchoghandjian, Hervé Luche, Pierre Grenot, Dominique Figarella-Branger, Geneviève Rougon, Marie Malissen, Franck Debarbieux Scientific Reports 6 (1), 26381-, 2016-05-19

...To address the cellular basis and dynamics of the inflammatory microenvironment in GBM, we established an orthotopic syngenic model by grafting GL261-DsRed cells in immunocompetent transgenic LysM-EGFP...

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Thomas Blank, Marco Prinz European Journal of Immunology 46 (6), 1340-1342, 2016-05-19

...<jats:p>The antibacterial enzyme lysozyme M (LysM) encoded by the Lyz2 gene is broadly expressed in myeloblasts, macrophages, and neutrophils, and thus has been used for a long time as a cell‐specific...

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Hiroyuki Takahara, Stéphane Hacquard, Anja Kombrink, H. Bleddyn Hughes, Vivek Halder, Guillaume P. Robin, Kei Hiruma, Ulla Neumann, Tomonori Shinya, Erich Kombrink, Naoto Shibuya, Bart P. H. J. Thomma, Richard J. O'Connell New Phytologist 211 (4), 1323-1337, 2016-05-13

...jats:list-item><jats:p>The genome of the hemibiotrophic anthracnose fungus, <jats:italic>Colletotrichum higginsianum</jats:italic>, encodes a large repertoire of candidate‐secreted effectors containing LysM...

DOI Web Site Web Site ほか2件 被引用文献10件 参考文献58件

Johannes Orthgiess, Martin Gericke, Kerstin Immig, Angela Schulz, Johannes Hirrlinger, Ingo Bechmann, Jens Eilers European Journal of Immunology 46 (6), 1529-1532, 2016-04-24

DOI Web Site Web Site 被引用文献2件

L-x Xia, W Hua, Y Jin, B-p Tian, Z-w Qiu, C Zhang, L-q Che, H-b Zhou, Y-f Wu, H-q Huang, F Lan, Y-h Ke, J J Lee, W Li, S-m Ying, Z-h Chen, H-h Shen Cell Death & Disease 7 (4), e2175-e2175, 2016-04-07

...Myeloid shp2 conditional knockout mice (<jats:italic>LysM</jats:italic><jats:sup><jats:italic>cre</jats:italic></jats:sup><jats:italic>shp2</jats:italic><jats:sup><jats:italic>flox/flox</jats:italic></...

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José M. Sanz‐Martín, José Ramón Pacheco‐Arjona, Víctor Bello‐Rico, Walter A. Vargas, Michel Monod, José M. Díaz‐Mínguez, Michael R. Thon, Serenella A. Sukno Molecular Plant Pathology 17 (7), 1048-1062, 2016-04-04

...fungus employs both Cgfl‐mediated and LysM protein‐mediated strategies to control chitin signalling....

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Phillip E. Klebba Journal of Bacteriology 198 (7), 1013-1021, 2016-04

...length of rigid polypeptide that spans the periplasm and a dimeric<jats:underline>C</jats:underline>-<jats:underline>t</jats:underline>erminal-ββαβ-<jats:underline>d</jats:underline>omain (CTD) with LysM...

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大沼 貴之 応用糖質科学：日本応用糖質科学会誌 6 (1), 15-20, 2016-02-20

...キチナーゼの構造機能相関およびその有効利用に関する研究はあまり進んでいなかった.本総説では筆者らが植物キチナーゼに焦点を当てて行った以下の研究の成果,(1)GH19キチナーゼ-基質複合体の立体構造の決定およびグライコシンターゼへの変換とそれらを利用したキチンオリゴ糖の化学-酵素合成法の確立,(2)植物クラスVキチナーゼの立体構造の決定と糖転移反応を増強した変異型酵素の開発,(3)キチンに結合性を示すLysM...

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Gautam Rishi, Eriza S. Secondes, Daniel F. Wallace, V. Nathan Subramaniam American Journal of Physiology-Gastrointestinal and Liver Physiology 310 (3), G171-G180, 2016-02-01

...We examined the role of TFR2 in macrophages by analysis of transgenic mice lacking Tfr2 in macrophages by crossing Tfr2<jats:sup> f/f</jats:sup> mice with LysM-Cre mice....

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Mattéa J. Finelli, Luis Sanchez-Pulido, Kevin X Liu, Kay E. Davies, Peter L. Oliver Journal of Biological Chemistry 291 (6), 2751-2763, 2016-02

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Luis Buendia, Tongming Wang, Ariane Girardin, Benoit Lefebvre New Phytologist 210 (1), 184-195, 2015-11-27

<jats:title>Summary</jats:title><jats:p> <jats:list list-type="bullet"> <jats:list-item><jats:p>Most plants have the ability to establish a symbiosis with arbuscular mycorrhizal …

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Mayumi Ueta, Ayaka Koga, Junichi Kikuta, Keiko Yamada, Sachi Kojima, Katsuhiko Shinomiya, Masaru Ishii, Shigeru Kinoshita British Journal of Ophthalmology 100 (3), 432-435, 2015-11-16

DOI Web Site 参考文献9件

Sweena M. Chaudhari, Judith C. Sluimer, Miriam Koch, Thomas L. Theelen, Helga D. Manthey, Martin Busch, Celia Caballero-Franco, Frederick Vogel, Clément Cochain, Jaroslav Pelisek, Mat J. Daemen, Manfred B. Lutz, Agnes Görlach, Stephan Kissler, Heike M. Hermanns, Alma Zernecke Arteriosclerosis, Thrombosis, and Vascular Biology 35 (11), 2316-2325, 2015-11

...Notably, deletion of<jats:italic>Hif1a</jats:italic>in LysM<jats:sup>+</jats:sup>bone marrow cells in<jats:italic>Ldlr</jats:italic><jats:sup>−/−</jats:sup>mice did not affect lesion formation or T-cell...

DOI Web Site 被引用文献3件

Amelia K. Pinto, James D. Brien, Chia-Ying Kao Lam, Syd Johnson, Cindy Chiang, John Hiscott, Vanessa V. Sarathy, Alan D. Barrett, Sujan Shresta, Michael S. Diamond mBio 6 (5), e01316-, 2015-10-30

...Here, we demonstrate that the specific deletion of<jats:italic>Ifnar</jats:italic>expression on subsets of murine myeloid cells (LysM Cre<jats:sup>+</jats:sup><jats:italic>Ifnar</jats:italic><jats:sup>...

DOI Web Site 被引用文献3件

Michael Gliem, Luisa Klotz, Nico van Rooijen, Hans-Peter Hartung, Sebastian Jander Stroke 46 (10), 2935-2942, 2015-10

...The role of PPARγ-dependent MO/MP differentiation was addressed in mice with myeloid cell–specific PPARγ-knockout (LysM-PPARγ(KO))....

DOI Web Site 被引用文献1件

Florian Rossmann, Susanne Brenzinger, Carina Knauer, Anja K. Dörrich, Sebastian Bubendorfer, Ulrike Ruppert, Gert Bange, Kai M. Thormann Molecular Microbiology 98 (4), 727-742, 2015-09-10

...Mediated by its periplasmic <jats:styled-content style="fixed-case">N</jats:styled-content>‐terminal <jats:styled-content style="fixed-case">LysM</jats:styled-content> domain, <jats:italic>Sp</jats:italic...

DOI Web Site Web Site 被引用文献6件

Sandra Hoegl, Kelley S. Brodsky, Michael R. Blackburn, Harry Karmouty-Quintana, Bernhard Zwissler, Holger K. Eltzschig The Journal of Immunology 195 (4), 1815-1824, 2015-08-15

...Interestingly, a head-to-head comparison of mice with deletion of Adora2b in the myeloid lineage (Adora2bloxP/loxP LysM Cre+), endothelial cells (Adora2bloxP/loxP VE-cadherin Cre+), or alveolar epithelial...

DOI PDF 被引用文献1件

Erik Limpens, Arjan van Zeijl, Rene Geurts Annual Review of Phytopathology 53 (1), 311-334, 2015-08-04

...Plants perceive microbial LCO molecules by specific LysM-domain-containing receptor-like kinases....

DOI Web Site 被引用文献2件

Saki Inamine, Shoko Onaga, Takayuki Ohnuma, Tamo Fukamizo, Toki Taira Bioscience, Biotechnology, and Biochemistry 79 (8), 1296-1304, 2015-08-03

...This is the first report of a chitinase from Equisetopsida, a class of fern plants, and the second report of a LysM-containing chitinase from a plant.</jats:p>...

DOI PDF 被引用文献2件

Shinichi Miyagawa, Ryohei Yatsu, Satomi Kohno, Brenna M. Doheny, Yukiko Ogino, Hiroshi Ishibashi, Yoshinao Katsu, Yasuhiko Ohta, Louis J. Guillette, Taisen Iguchi Endocrinology 156 (8), 2795-2806, 2015-08

...In turn, increased osteoclast activity in LysM-Cre Runx1fl/fl mice likely contributed to a decrease in bone mass....

DOI DOI PDF ほか1件 被引用文献4件 参考文献28件

Esther Parada, Izaskun Buendia, Elisa Navarro, Carlos Avendaño, Javier Egea, Manuela G. López Molecular Nutrition & Food Research 59 (9), 1690-1700, 2015-06-30

...Most interesting was the observation that the glial protective effects related to HO‐1 induction were microglial specific as shown in glial cultures from LysM<jats:sup>Cre</jats:sup>Hmox<jats:sup>∆/∆</...

DOI Web Site Web Site 被引用文献1件

Neng-Yu Lin, Chih-Wei Chen, Rosebeth Kagwiria, Ruifang Liang, Christian Beyer, Alfiya Distler, Julia Luther, Klaus Engelke, Georg Schett, Jörg HW Distler Annals of the Rheumatic Diseases 75 (6), 1203-1210, 2015-06-25

...</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Selective deletion of Atg7 in monocytes from Atg7<jats:sup>fl/fl</jats:sup>_x_LysM-Cre mice mitigated glucocorticoid-induced and OVX-induced...

DOI Web Site 被引用文献2件

Ryohei Sekimoto, Shiro Fukuda, Norikazu Maeda, Yu Tsushima, Keisuke Matsuda, Takuya Mori, Hideaki Nakatsuji, Hitoshi Nishizawa, Ken Kishida, Junichi Kikuta, Yumiko Maijima, Tohru Funahashi, Masaru Ishii, Iichiro Shimomura Proceedings of the National Academy of Sciences 112 (16), E2058-, 2015-04-06

...Mobility of LysM <jats:sup>EGFP</jats:sup> -positive macrophages was activated just 5 d after high-fat and high-sucrose (HF/HS) diet before the development of obesity....

DOI Web Site Web Site 被引用文献9件 参考文献34件

Jaslyn E. M. M. Wong, Søren Roi Midtgaard, Kira Gysel, Mikkel B. Thygesen, Kasper K. Sørensen, Knud J. Jensen, Jens Stougaard, Søren Thirup, Mickaël Blaise Acta Crystallographica Section D Biological Crystallography 71 (3), 592-605, 2015-02-26

...LysM domains and short or long chitin oligomers....

DOI PDF 被引用文献2件

Gunseli Bayram Akcapinar, Lisa Kappel, Osman Ugur Sezerman, Verena Seidl-Seiboth Current Genetics 61 (2), 103-113, 2015-01-15

DOI PDF Web Site ほか1件 被引用文献5件

谷口 隆志, 浅野 善英, 赤股 要, 野田 真史, 高橋 岳浩, 市村 洋平, 遠山 哲夫, 三枝 良輔, 吉崎 歩, Trojanowska Maria, 佐藤 伸一 日本臨床免疫学会会誌 38 (4), 332a-332a, 2015

...はこれまでに血管内皮細胞におけるFli1の恒常的発現低下が血管新生の異常活性化を引き起こし，SScにおける血管の恒常性の破綻や血管障害を再現することを明らかにしてきたが，骨髄系細胞におけるFli1の発現低下が血管の恒常性に及ぼす影響については未だ明らかではない．そこで今回我々は，骨髄系細胞におけるFli1の恒常的発現低下が血管の恒常性に及ぼす影響を明らかにするため，骨髄系細胞特異的Fli1欠失マウス（LysM-Cre...

DOI Web Site PubMed ほか1件

新着論文レビュー 96-, 2015

DOI

Xiaowei Zhang, Wentao Dong, Jongho Sun, Feng Feng, Yiwen Deng, Zuhua He, Giles E.D. Oldroyd, Ertao Wang The Plant Journal 81 (2), 258-267, 2014-12-12

...Chitin oligosaccharides also act as microbe associated molecular patterns that promote plant immunity via similar LysM receptor‐like kinases....

DOI Web Site Web Site 被引用文献13件

Ying Ao, Zhangqun Li, Dongru Feng, Feng Xiong, Jun Liu, Jian‐Feng Li, Menglong Wang, Jinfa Wang, Bing Liu, Hong‐Bin Wang The Plant Journal 80 (6), 1072-1084, 2014-12

...Here, we demonstrate that the rice LysM receptor‐like kinase Os<jats:styled-content style="fixed-case">CERK</jats:styled-content>1, a key component of the chitin elicitor signaling pathway, also plays...

DOI Web Site Web Site 被引用文献12件

Jack C. Leo, Philipp Oberhettinger, Manish Chaubey, Monika Schütz, Daniel Kühner, Ute Bertsche, Heinz Schwarz, Friedrich Götz, Ingo B. Autenrieth, Murray Coles, Dirk Linke Molecular Microbiology 95 (1), 80-100, 2014-11-24

...We further show that dimerisation and peptidoglycan binding are general features of <jats:styled-content style="fixed-case">LysM</jats:styled-content>‐containing inverse autotransporters....

DOI Web Site Web Site ほか1件 被引用文献2件

Meritxell Antolín‐Llovera, Elena Kristin Petutsching, Martina Katharina Ried, Volker Lipka, Thorsten Nürnberger, Silke Robatzek, Martin Parniske New Phytologist 204 (4), 791-802, 2014-11-04

...A critical step in their activation is ligand‐induced homo‐ or hetero‐oligomerization of leucine‐rich repeat (<jats:styled-content style="fixed-case">LRR</jats:styled-content>)‐ and/or lysin motif (LysM...

DOI Web Site Web Site ほか2件 被引用文献3件

Yusuke Kouzai, Susumu Mochizuki, Keisuke Nakajima, Yoshitake Desaki, Masahiro Hayafune, Hideo Miyazaki, Naoki Yokotani, Kenjirou Ozawa, Eiichi Minami, Hanae Kaku, Naoto Shibuya, Yoko Nishizawa Molecular Plant-Microbe Interactions® 27 (9), 975-982, 2014-09

...<jats:p> OsCERK1 is a rice receptor-like kinase that mediates the signal of a fungal cell wall component, chitin, by coordinating with a lysin motif (LysM)-containing protein CEBiP....

DOI Web Site 被引用文献25件 参考文献45件

Roland Züst, Ying-Xiu Toh, Iris Valdés, Daniela Cerny, Julia Heinrich, Lisset Hermida, Ernesto Marcos, Gerardo Guillén, Ulrich Kalinke, Pei-Yong Shi, Katja Fink Journal of Virology 88 (13), 7276-7285, 2014-07

...We show that mice lacking the IFN receptor on either CD11c- or LysM-expressing cells (conditional IFNAR mice) are susceptible to dengue virus infection....

DOI Web Site 被引用文献3件

Stéphane Mesnage, Mariano Dellarole, Nicola J. Baxter, Jean-Baptiste Rouget, Jordan D. Dimitrov, Ning Wang, Yukari Fujimoto, Andrea M. Hounslow, Sébastien Lacroix-Desmazes, Koichi Fukase, Simon J. Foster, Michael P. Williamson Nature Communications 5 (1), 4269-, 2014-06-30

...Our results suggest that peptide stems modulate LysM binding to peptidoglycan....

DOI PDF Web Site 被引用文献8件 参考文献62件

Eileen M. Bauer, R. Savanh Chanthaphavong, Chhinder P. Sodhi, David J. Hackam, Timothy R. Billiar, Philip M. Bauer Circulation Research 114 (10), 1596-1600, 2014-05-09

...However, the deletion of TLR4 from myeloid lineage cells had no effect on the development of PH because we found no difference in RV systolic pressure or RV hypertrophy in wild-type versus LysM-TLR4...

DOI Web Site 被引用文献1件

Ganesh Ram R. Visweswaran, Kees Leenhouts, Maarten van Roosmalen, Jan Kok, Girbe Buist Applied Microbiology and Biotechnology 2014-03-21

DOI PDF Web Site ほか1件 被引用文献1件

Chiara Paparella, Daniel Valentin Savatin, Lucia Marti, Giulia De Lorenzo, Simone Ferrari Plant Physiology 165 (1), 262-276, 2014-03-17

...<jats:title>Abstract</jats:title><jats:p>Transmembrane receptor-like kinases characterized by the presence of one or more lysin motif (LysM) domains in the extracytoplasmic portion (LysM-containing receptor-like...

DOI PDF 被引用文献2件

Wing-Sham Lee, Jason J. Rudd, Kim E. Hammond-Kosack, Kostya Kanyuka Molecular Plant-Microbe Interactions® 27 (3), 236-243, 2014-03

...(homologue of Ecp6) deletion mutant, while the Mg1LysM deletion mutant was fully pathogenic toward both silenced and wild-type wheat leaves....

DOI Web Site 被引用文献3件

Xiao-Lin Chen, Tao Shi, Jun Yang, Wei Shi, Xusheng Gao, Deng Chen, Xiaowen Xu, Jin-Rong Xu, Nicholas J. Talbot, You-Liang Peng The Plant Cell 26 (3), 1360-1376, 2014-03-01

...In this study, the ASPARAGINE-LINKED GLYCOSYLATION3 (ALG3)-mediated N-glycosylation of the effector, Secreted LysM Protein1 (Slp1), was found to be essential for its activity in the rice blast fungus Magnaporthe...

DOI PDF 被引用文献5件

Ning Lu, Lihong Wang, Hailong Cao, Liping Liu, Luc Van Kaer, Mary K. Washington, Michael J. Rosen, Philip E. Dubé, Keith T. Wilson, Xiubao Ren, Xishan Hao, D. Brent Polk, Fang Yan The Journal of Immunology 192 (3), 1013-1023, 2014-02-01

...DSS-induced acute colitis was ameliorated, and recovery from colitis was promoted in Egfrfl/flLysM-Cre mice with myeloid cell–specific deletion of EGFR, compared with LysM-Cre mice....

DOI PDF 被引用文献1件

Louise Grant, Kirsty D. Shearer, Alicja Czopek, Emma K. Lees, Carl Owen, Abdelali Agouni, James Workman, Cristina Martin-Granados, John V. Forrester, Heather M. Wilson, Nimesh Mody, Mirela Delibegovic Diabetes 63 (2), 456-470, 2014-01-16

...We assessed the role of macrophage PTP1B in inflammation and whole-body metabolism using myeloid-cell (LysM) PTP1B knockout mice (LysM PTP1B)....

DOI PDF PDF 被引用文献5件

Jaslyn E. M. M. Wong, Husam M. A. B. Alsarraf, Jørn Døvling Kaspersen, Jan Skov Pedersen, Jens Stougaard, Søren Thirup, Mickaël Blaise The FEBS Journal 281 (4), 1196-1208, 2014-01-13

<jats:p>Cellulose, chitin and peptidoglycan are major long‐chain carbohydrates in living organisms, and constitute a substantial fraction of the biomass. Characterization of the biochemical basis of …

DOI Web Site Web Site 被引用文献1件

北奥 喜仁, 平良 東紀, 沼田 倫征, 深溝 慶, 大沼 貴之 応用糖質科学：日本応用糖質科学会誌 4 (3), B55-, 2014

DOI Web Site

Iván Ballesteros, María I Cuartero, Jesús M Pradillo, Juan de la Parra, Alberto Pérez-Ruiz, Ángel Corbí, Mercedes Ricote, John A Hamilton, Mónica Sobrado, José Vivancos, Florentino Nombela, Ignacio Lizasoain, María A Moro Journal of Leukocyte Biology 95 (4), 587-598, 2013-12-12

...BMMs were obtained from Lys-M Cre+ PPARγf/f and Lys-M Cre− PPARγf/f mice....

DOI PDF 被引用文献4件

Anja Kombrink, Bart P. H. J. Thomma PLoS Pathogens 9 (12), e1003769-, 2013-12-12

DOI Web Site 被引用文献2件

Yvonne G. Y. Chan, Matthew B. Frankel, Vanina Dengler, Olaf Schneewind, Dominique Missiakas Journal of Bacteriology 195 (20), 4650-4659, 2013-10-15

...Further, Δ <jats:italic>lcp</jats:italic> mutant staphylococci no longer restricted the deposition of LysM-type murein hydrolases to cell division sites, which was associated with...

DOI Web Site 被引用文献2件

Caroline Gutjahr, Martin Parniske Annual Review of Cell and Developmental Biology 29 (1), 593-617, 2013-10-06

...Calcium spiking is triggered by chitooligosaccharides released by AM fungi that are probably perceived via LysM domain receptor kinases....

DOI Web Site 被引用文献13件

Heidi A. Schreiber, Jakob Loschko, Roos A. Karssemeijer, Amelia Escolano, Matthew M. Meredith, Daniel Mucida, Pierre Guermonprez, Michel C. Nussenzweig Journal of Experimental Medicine 210 (10), 2025-2039, 2013-09-16

...Here, we describe a two-gene approach that requires overlapping expression of LysM and Csf1r to define and deplete monocytes and macrophages....

DOI PDF 被引用文献3件

Keith K. Fenrich, Pascal Weber, Geneviève Rougon, Franck Debarbieux The Journal of Physiology 591 (19), 4895-4902, 2013-09-10

...Using chronic, quantitative intravital two‐photon microscopy of adult mice with SCI, here we show that infiltrating lysozyme M (LysM(+)) and resident CD11c(+) myelomonocytic cells have distinct spatiotemporal...

DOI Web Site Web Site 被引用文献1件

Eric S. Wohleb, Nicole D. Powell, Jonathan P. Godbout, John F. Sheridan The Journal of Neuroscience 33 (34), 13820-13833, 2013-08-21

...LysM-GFP<jats:sup>+</jats:sup>mice showed that RSD increased recruitment of GFP<jats:sup>+</jats:sup>macrophages to the brain and increased their presence within the perivascular space (PVS)....

DOI Web Site 被引用文献26件

Andrea Sánchez-Vallet, Raspudin Saleem-Batcha, Anja Kombrink, Guido Hansen, Dirk-Jan Valkenburg, Bart PHJ Thomma, Jeroen R Mesters eLife 2 e00790-, 2013-07-02

...Structural analysis of the LysM effector Ecp6 of the fungal tomato pathogen Cladosporium fulvum reveals a novel mechanism for chitin binding, mediated by intrachain LysM dimerization, leading to a chitin-binding...

DOI PDF Web Site ほか1件 被引用文献8件

Xiu-Zhen Shi, Jing Zhou, Jiang-Feng Lan, Yu-Ping Jia, Xiao-Fan Zhao, Jin-Xing Wang Developmental & Comparative Immunology 40 (3-4), 311-319, 2013-07

DOI Web Site Web Site 被引用文献1件

Jiro Ikeda, Toshihiro Ichiki, Hirohide Matsuura, Eriko Inoue, Junji Kishimoto, Aya Watanabe, Chikahiro Sankoda, Shiro Kitamoto, Tomotake Tokunou, Kotaro Takeda, Guo‐Hua Fong, Kenji Sunagawa Journal of the American Heart Association 2 (3), 2013-05-20

...styled-content style="fixed-case">PHD</jats:styled-content> 2‐deficient mice (MyPHD2KO) were generated by crossing <jats:italic>Phd2</jats:italic> ‐floxed mice with LysM‐Cre...

DOI Web Site 被引用文献2件 参考文献35件

Meihong Deng, Melanie J. Scott, Patricia Loughran, Gregory Gibson, Chhinder Sodhi, Simon Watkins, David Hackam, Timothy R. Billiar The Journal of Immunology 190 (10), 5152-5160, 2013-05-15

...LysM-TLR4 was required for phagocytosis and efficient bacterial clearance in the absence of antibiotics....

DOI PDF 被引用文献5件

Toru Kariu, Xiuli Yang, Carolyn B. Marks, Xinyue Zhang, Utpal Pal Molecular Microbiology 88 (3), 510-522, 2013-03-26

...However, the <jats:styled-content style="fixed-case">LysM</jats:styled-content> domain or the precisely processed <jats:styled-content style="fixed-case">BB</jats:styled-content>0323 product is essential...

DOI Web Site Web Site 被引用文献1件

Kiwamu Tanaka, Cuong T. Nguyen, Yan Liang, Yangrong Cao, Gary Stacey Plant Signaling & Behavior 8 (1), e22598-, 2013-01

DOI Web Site 被引用文献1件

Carly Page, Lindsay Goicochea, Krystal Matthews, Yong Zhang, Peter Klover, Michael J. Holtzman, Lothar Hennighausen, Matthew Frieman Journal of Virology 86 (24), 13334-13349, 2012-12-15

...Following infection, LysM/STAT1 mice display severe lung pathology, while FoxJ1/STAT1 mice display normal lung pathology....

DOI Web Site 被引用文献1件

Nicholas J. Roberts, Giulia Morieri, Gurpreet Kalsi, Alan Rose, Jiri Stiller, Anne Edwards, Fang Xie, Peter M. Gresshoff, Giles E.D. Oldroyd, J. Allan Downie, Marilynn E. Etzler Plant Physiology 161 (1), 556-567, 2012-11-07

...Genetic studies have revealed that the perception of Nod factors involves LysM domain receptor-like kinases, while biochemical approaches have identified LECTIN NUCLEOTIDE PHOSPHOHYDROLASE (LNP) as a Nod...

DOI PDF 被引用文献3件

Diego A. Martinez, Brian G. Oliver, Yvonne Gräser, Jonathan M. Goldberg, Wenjun Li, Nilce M. Martinez-Rossi, Michel Monod, Ekaterina Shelest, Richard C. Barton, Elizabeth Birch, Axel A. Brakhage, Zehua Chen, Sarah J. Gurr, David Heiman, Joseph Heitman, Idit Kosti, Antonio Rossi, Sakina Saif, Marketa Samalova, Charles W. Saunders, Terrance Shea, Richard C. Summerbell, Jun Xu, Sarah Young, Qiandong Zeng, Bruce W. Birren, Christina A. Cuomo, Theodore C. White mBio 3 (5), e00212-, 2012-11

...These LysM domains differ in sequence from those in other species in regions of the peptide that could affect substrate binding....

DOI Web Site 被引用文献6件

Eliseo F. Castillo, Alexander Dekonenko, John Arko-Mensah, Michael A. Mandell, Nicolas Dupont, Shanya Jiang, Monica Delgado-Vargas, Graham S. Timmins, Dhruva Bhattacharya, Hongliang Yang, Julie Hutt, C. Rick Lyons, Karen M. Dobos, Vojo Deretic Proceedings of the National Academy of Sciences 109 (46), 3168-, 2012-10-23

...Macrophages from uninfected Atg5 <jats:sup>fl/fl</jats:sup> LysM-Cre <jats:sup>+</jats:sup> mice displayed a cell-autonomous IL-1α hypersecretion phenotype...

DOI Web Site 被引用文献9件

Angela M. Kaindl, Vincent Degos, Stéphane Peineau, Elodie Gouadon, Vibol Chhor, Gauthier Loron, Tifenn Le Charpentier, Julien Josserand, Carine Ali, Denis Vivien, Graham L. Collingridge, Alain Lombet, Lina Issa, Frédérique Rene, Jean‐Philippe Loeffler, Annemieke Kavelaars, Catherine Verney, Jean Mantz, Pierre Gressens Annals of Neurology 72 (4), 536-549, 2012-10

...We generated <jats:italic>Nr1 LoxP</jats:italic><jats:sup>+/+</jats:sup><jats:italic>LysM Cre</jats:italic><jats:sup>+/−</jats:sup> mice lacking the NMDAR subunit NR1 in cells of the myeloid lineage....

DOI Web Site Web Site 被引用文献5件

Pauline Rival, Françoise de Billy, Jean-Jacques Bono, Clare Gough, Charles Rosenberg, Sandra Bensmihen Development 139 (18), 3383-3391, 2012-09-15

...Here, we have addressed the roles of two key symbiotic genes of Medicago truncatula, the lysin motif (LysM) domain-receptor like kinase gene NFP and the calcium- and calmodulin-dependent protein kinase...

DOI PDF 被引用文献4件

Meritxell Antolín-Llovera, Martina K. Ried, Andreas Binder, Martin Parniske Annual Review of Phytopathology 50 (1), 451-473, 2012-09-08

...RLKs with lysin-motif (LysM) ectodomains confer recognitional specificity toward N-acetylglucosamine-containing signaling molecules, such as chitin, peptidoglycan (PGN), and rhizobial nodulation factor...

DOI Web Site 被引用文献7件

Yariv Brotman, Udi Landau, Smadar Pnini, Jan Lisec, Salma Balazadeh, Bernd Mueller-Roeber, Aviah Zilberstein, Lothar Willmitzer, Ilan Chet, Ada Viterbo Molecular Plant 5 (5), 1113-1124, 2012-09

DOI Web Site Web Site 被引用文献6件

Monica Guma, Deepa Hammaker, Katharyn Topolewski, Maripat Corr, David L. Boyle, Michael Karin, Gary S. Firestein Arthritis & Rheumatism 64 (9), 2887-2895, 2012-08-27

...Antigen‐induced arthritis was also induced in p38α<jats:sup>ΔLysM</jats:sup> mice....

DOI Web Site Web Site 被引用文献1件

Andrea A. Gust, Roland Willmann, Yoshitake Desaki, Heini M. Grabherr, Thorsten Nürnberger Trends in Plant Science 17 (8), 495-502, 2012-08

DOI Web Site Web Site 被引用文献5件

Yoshinaga Kawano, Jun Nakae, Nobuyuki Watanabe, Shiho Fujisaka, Kristy Iskandar, Risa Sekioka, Yoshitake Hayashi, Kazuyuki Tobe, Masato Kasuga, Tetsuo Noda, Akihiko Yoshimura, Masafumi Onodera, Hiroshi Itoh Diabetes 61 (8), 1935-1948, 2012-07-17

...), or a transactivation-defective Foxo1 (Δ256Foxo1LysM)....

DOI PDF PDF 被引用文献9件 参考文献37件

Jinrong Wan, Kiwamu Tanaka, Xue-Cheng Zhang, Geon Hui Son, Laurent Brechenmacher, Tran Hong Nha Nguyen, Gary Stacey Plant Physiology 160 (1), 396-406, 2012-06-28

...sativa), the LysM-containing protein, CEBiP (for chitin elicitor-binding protein), was shown to be involved in chitin recognition....

DOI PDF 被引用文献13件

Hanneke LDM Willemen, Xiao-Jiao Huo, Qi-Liang Mao-Ying, Jitske Zijlstra, Cobi J Heijnen, Annemieke Kavelaars Journal of Neuroinflammation 9 (1), 143-, 2012-06-25

...The miR-124 treatment also normalized expression of spinal M1/M2 markers of LysM-GRK2<jats:sup>+/−</jats:sup> mice....

DOI PDF Web Site ほか1件 被引用文献3件

Sergey V Novitskiy, Michael W Pickup, Anna Chytil, Dina Polosukhina, Philip Owens, Harold L Moses Journal of Leukocyte Biology 92 (3), 641-651, 2012-06-08

...</jats:p> <jats:p>By crossing LysM-Cre and TGF-β type II receptor (Tgfbr2) floxed mice we achieved specific deletion of Tgfbr2 in myeloid cells (Tgfbr2MyeKO mice). S.c....

DOI PDF 被引用文献2件

Lisa F. Czaja, Claudia Hogekamp, Patrick Lamm, Fabienne Maillet, Eduardo Andres Martinez, Eric Samain, Jean Dénarié, Helge Küster, Natalija Hohnjec Plant Physiology 159 (4), 1671-1685, 2012-05-31

...Irrespective of different outcomes, the perception of symbiotic LCOs in Medicago truncatula is mediated by the LysM receptor kinase M. truncatula Nod factor perception (MtNFP)....

DOI PDF 被引用文献7件

Anna Bertram, Hong Zhang, Sibylle von Vietinghoff, Carmen de Pablo, Hermann Haller, Nelli Shushakova, Klaus Ley The Journal of Immunology 188 (8), 4043-4051, 2012-04-15

...To investigate the role of PKC-θ in neutrophil adhesion, we performed intravital microscopy in cremaster venules of mice reconstituted with bone marrow from LysM-GFP+ (wild-type [WT]) and PKC-θ gene-deficient...

DOI PDF 被引用文献1件

Zhipeng Wang, Cristin D. Berkey, Paula I. Watnick The Journal of Immunology 188 (8), 3993-4000, 2012-04-15

...This genetic locus, which we have named mustard (mtd), contains a LysM domain, often involved in carbohydrate recognition, and a TLDc domain of unknown function....

DOI PDF 被引用文献1件

Nadin Wimmer, Barbara Huber, Nicola Barabas, Johann Röhrl, Klaus Pfeffer, Thomas Hehlgans The Journal of Immunology 188 (7), 3426-3433, 2012-04-01

...Furthermore, we have generated cell type-specific LTβR-deficient mice with ablation of LTβR expression on macrophages/neutrophils (LTβRflox/flox × LysM-Cre)....

DOI PDF 被引用文献3件

Jun Li, Hui‐Chen Hsu, PingAr Yang, Qi Wu, Hao Li, Laura E. Edgington, Matthew Bogyo, Robert P. Kimberly, John D. Mountz Arthritis & Rheumatism 64 (4), 1098-1109, 2012-03-27

...In human/mouse DR5‐transgenic LysM.Cre mice, transgenic DR5 was restrictively expressed on macrophages....

DOI Web Site Web Site 被引用文献1件

Carla M. Cuda, Hemant Agrawal, Alexander V. Misharin, G. Kenneth Haines, Jack Hutcheson, Evan Weber, Joseph A. Schoenfeldt, Chandra Mohan, Richard M. Pope, Harris Perlman Arthritis & Rheumatism 64 (3), 808-820, 2012-02-28

...The genotype for Cre<jats:sup>LysM</jats:sup>Fas<jats:sup>flox/flox</jats:sup> mice was verified by polymerase chain reaction and flow cytometric analysis....

DOI Web Site Web Site 被引用文献1件

Cecilia A. Silva, Carlos J. Blondel, Carolina P. Quezada, Steffen Porwollik, Helene L. Andrews-Polymenis, Cecilia S. Toro, Mercedes Zaldívar, Inés Contreras, Michael McClelland, Carlos A. Santiviago Infection and Immunity 80 (2), 839-849, 2012-02

...SEN1970 to SEN1999</jats:italic> ), and a type VI secretion system remnant <jats:italic>SEN1001</jats:italic> , encoding a hypothetical protein containing a lysin motif (LysM...

DOI Web Site 被引用文献1件

Thomas A. Mentlak, Anja Kombrink, Tomonori Shinya, Lauren S. Ryder, Ippei Otomo, Hiromasa Saitoh, Ryohei Terauchi, Yoko Nishizawa, Naoto Shibuya, Bart P.H.J. Thomma, Nicholas J. Talbot The Plant Cell 24 (1), 322-335, 2012-01-01

...Here, we show that the rice blast fungus Magnaporthe oryzae overcomes this first line of plant defense by secreting an effector protein, Secreted LysM Protein1 (Slp1), during invasion of new rice cells...

DOI PDF 被引用文献25件 参考文献41件

賀来 華江, 新屋 友規, 渋谷 直人 化学と生物 50 (1), 52-58, 2012

DOI Web Site 医中誌 参考文献34件

香山 尚子, 竹田 潔 日本臨床免疫学会会誌 35 (4), 315a-315a, 2012

...sup>+</sup>制御性ミエロイド細胞（M_reg細胞）がCD4⁺ T細胞と極めて高い親和性で結合すること，さらにIL-10/Stat3シグナル依存的にCD80/86の発現を低下させることでT細胞の増殖を抑制することを明らかにした．また，ナイーブT細胞移入腸炎モデルマウスへのM_reg細胞投与が腸炎発症を抑制すること，腸炎を自然発症するLysM-cre...

DOI Web Site 医中誌

大沼 貴之, 北奥 喜仁, 翁長 彰子, 平良 東紀, 深溝 慶 応用糖質科学：日本応用糖質科学会誌 2 (3), B51-, 2012

DOI Web Site

Niccolò Terrando, Lars I. Eriksson, Jae Kyu Ryu, Ting Yang, Claudia Monaco, Marc Feldmann, Malin Jonsson Fagerlund, Israel F. Charo, Katerina Akassoglou, Mervyn Maze Annals of Neurology 70 (6), 986-995, 2011-12

...:</jats:title><jats:p>C57BL/6J, <jats:italic>Ccr2<jats:sup>RFP/+</jats:sup>Cx3cr1<jats:sup>GFP/+</jats:sup></jats:italic>, <jats:italic>Ikk<jats:sup>F/F</jats:sup></jats:italic> mice and <jats:italic>LysM‐Cre...

DOI Web Site Web Site 被引用文献5件

Roland Willmann, Heini M. Lajunen, Gitte Erbs, Mari-Anne Newman, Dagmar Kolb, Kenichi Tsuda, Fumiaki Katagiri, Judith Fliegmann, Jean-Jacques Bono, Julie V. Cullimore, Anna K. Jehle, Friedrich Götz, Andreas Kulik, Antonio Molinaro, Volker Lipka, Andrea A. Gust, Thorsten Nürnberger Proceedings of the National Academy of Sciences 108 (49), 19824-19829, 2011-11-21

...Here we show that PGN sensing and immunity to bacterial infection in <jats:italic>Arabidopsis thaliana</jats:italic> requires three lysin-motif (LysM) domain proteins....

DOI Web Site 被引用文献30件

Einar E. Eriksson Circulation 124 (19), 2129-2138, 2011-11-08

...jats:sup>−/−</jats:sup> mice carrying a knock-in mutation for enhanced green fluorescent protein (EGFP) in the lysozyme M locus (ApoE <jats:sup>−/−</jats:sup> /lysM...

DOI Web Site 被引用文献1件

Rebecca L. Schmidt, Holly C. Filak, Jack D. Lemon, Terry A. Potter, Laurel L. Lenz PLoS Pathogens 7 (11), e1002368-, 2011-11-03

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Lirong Zeng, André C. Velásquez, Kathy R. Munkvold, Jingwei Zhang, Gregory B. Martin The Plant Journal 69 (1), 92-103, 2011-10-14

...The F173A substitution disrupts the interaction of AvrPtoB with Bti9 and SlLyk13, suggesting that these LysM‐RLKs are its virulence targets....

DOI Web Site Web Site 被引用文献1件

Philip Wenzel, Maike Knorr, Sabine Kossmann, Jan Stratmann, Michael Hausding, Swenja Schuhmacher, Susanne H. Karbach, Melanie Schwenk, Nir Yogev, Eberhard Schulz, Matthias Oelze, Stephan Grabbe, Helmut Jonuleit, Christian Becker, Andreas Daiber, Ari Waisman, Thomas Münzel Circulation 124 (12), 1370-1381, 2011-09-20

...Selective ablation of lysozyme M-positive (LysM <jats:sup>+</jats:sup> ) myelomonocytic cells by low-dose diphtheria toxin in mice with inducible expression of the diphtheria...

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Chris S. Rae, Aimee Geissler, Paul C. Adamson, Daniel A. Portnoy Infection and Immunity 79 (9), 3596-3606, 2011-09

...Each of the<jats:italic>in vitro</jats:italic>phenotypes was rescued upon infection of LysM<jats:sup>−</jats:sup>macrophages....

DOI Web Site 被引用文献1件

Zhuzhen Zhang, Fan Zhang, Peng An, Xin Guo, Yuanyuan Shen, Yunlong Tao, Qian Wu, Yuchao Zhang, Yu Yu, Bo Ning, Guangjun Nie, Mitchell D. Knutson, Gregory J. Anderson, Fudi Wang Blood 118 (7), 1912-1922, 2011-08-18

...We found that expression levels of TNF-α and IL-6 were significantly enhanced in Fpn1LysM/LysM macrophages lacking Fpn1....

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Clare Gough, Julie Cullimore Molecular Plant-Microbe Interactions® 24 (8), 867-878, 2011-08

...Together these studies show that structurally related signals and the LysM receptor family are key components of both nodulation and mycorrhization....

DOI Web Site 被引用文献1件

Nirupa Sachithanandan, Kate L. Graham, Sandra Galic, Jane E. Honeyman, Stacey L. Fynch, Kimberly A. Hewitt, Gregory R. Steinberg, Thomas W. Kay Diabetes 60 (8), 2023-2031, 2011-07-18

...promoter (SOCS1 LysM-Cre)....

DOI PDF PDF 被引用文献3件

Judith Fliegmann, Sandra Uhlenbroich, Tomonori Shinya, Yves Martinez, Benoit Lefebvre, Naoto Shibuya, Jean-Jacques Bono Plant Physiology and Biochemistry 49 (7), 709-720, 2011-07

DOI Web Site Web Site 被引用文献2件 参考文献52件

Leonardus M.I. Koharudin, Arturo R. Viscomi, Barbara Montanini, Michael J. Kershaw, Nicholas J. Talbot, Simone Ottonello, Angela M. Gronenborn Structure 19 (5), 662-674, 2011-05

DOI Web Site Web Site 被引用文献2件

Rosalind Marshall, Anja Kombrink, Juliet Motteram, Elisa Loza-Reyes, John Lucas, Kim E. Hammond-Kosack, Bart P.H.J. Thomma, Jason J. Rudd Plant Physiology 156 (2), 756-769, 2011-04-05

...Three LysM effector homologs are present in the M. graminicola genome, referred to as Mg3LysM, Mg1LysM, and MgxLysM....

DOI PDF 被引用文献9件

Rik Op den Camp, Arend Streng, Stéphane De Mita, Qingqin Cao, Elisa Polone, Wei Liu, Jetty S. S. Ammiraju, Dave Kudrna, Rod Wing, Andreas Untergasser, Ton Bisseling, René Geurts Science 331 (6019), 909-912, 2011-02-18

<jats:p> <jats:italic>Parasponia</jats:italic> uses a mycorrhizal signaling receptor essential for arbuscle formation to control rhizobium nodule symbiosis. </jats:p>

DOI Web Site 被引用文献10件

Hania Wehbi, Eder Portillo, Hanjeong Harvey, Anthony E. Shimkoff, Edie M. Scheurwater, P. Lynne Howell, Lori L. Burrows Journal of Bacteriology 193 (2), 540-550, 2011-01-15

...PG pulldown assays showed that the N terminus of FimV bound PG in a LysM motif-dependent manner, and a mutant with an in-frame chromosomal deletion of the LysM motif had reduced motility, secretin levels...

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Claire Gordy, Heather Pua, Gregory D. Sempowski, You-Wen He Blood 117 (2), 618-629, 2011-01-13

...develop severe neutrophilia, splenomegaly, extramedullary hematopoiesis, decreased body weight, and increased production of granulocyte colony-stimulating factor (G-CSF) and IL-1β, but not IL-17. c-FLIPf/f LysM-Cre...

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下田 宜司, 韓 路, 林 晃之, 征矢野 敬, 横田 圭祐, 林 誠, 今泉(安楽) 温子 植物の生長調節 46 (2), 94-102, 2011

...., (1) Perception of host-specific NFs by LysM receptor kinases, (2) Induction of Ca^<2+> spiking and transduction of Ca^<2+> signals through common symbiosis pathway, and (3) Rhizobial infection via intracellular...

DOI Web Site 参考文献25件