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Tachibana, Masako, Inada, Toshiya, Kimura, Hiroki, Ito, Mikako, Kuwatsuka, Yachiyo, Kinoshita, Fumie, Mori, Daisuke, Ohno, Kinji Asian Journal of Psychiatry 96 104036-, 2024-06

...ELF-ELME appears to ameliorate depressive symptoms in patients with major depressive disorder safely and effectively, suggesting that it could be used as an alternative treatment for depressive patients...

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Nagayasu Kazuki Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 47 (3), 556-561, 2024-03-01

...We established quantitative prediction methods for pharmacological activity using only chemical structures to translate the biological understanding of mental disorders, including major depressive disorders...

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水野 康弘, 有木 永子, 北島 正人, 浅川 けい, 津川 律子 人間科学研究 45 99-110, 2024-03-01

自死予防のために、若年うつ病者のLMTの特徴を、SDSで希死念慮の頻度を問う第19項目（SDS_Q19）およびSCTの刺激語「自殺」への記述内容を用いて調べることが本研究の目的であった。対象者は、うつ病群として精神科外来通院中の20代うつ病者30名と、健常群として同年代の大学生48名であった。結果として、SDS_Q19において、うつ病群で希死念慮頻度が最高点「ほとんどいつも」と回答した者が９名（…

DOI 機関リポジトリ

MATSUURA Yuto, YAMAGUCHI Satoru, YASUNO Fumiko, SAKAI Tomomi 日本温泉気候物理医学会雑誌 87 (1), 21-21, 2024-02-29

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Waka Nogami, Atsuo Nakagawa, Noriko Kato, Yohei Sasaki, Taishiro Kishimoto, Masaru Horikoshi, Masaru Mimura Cognitive and Behavioral Practice 30 (4), 635-645, 2023-11

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Naomi Hasegawa, Yuka Yasuda, Norio Yasui‐Furukori, Hisashi Yamada, Hikaru Hori, Kayo Ichihashi, Yoshikazu Takaesu, Hitoshi Iida, Hiroyuki Muraoka, Fumitoshi Kodaka, Jun‐ichi Iga, Naoki Hashimoto, Kazuyoshi Ogasawara, Kazutaka Ohi, Kentaro Fukumoto, Shusuke Numata, Takashi Tsuboi, Masahide Usami, Akitoyo Hishimoto, Ryuji Furihata, Taishiro Kishimoto, Toshinori Nakamura, Eiichi Katsumoto, Shinichiro Ochi, Tatsuya Nagasawa, Kiyokazu Atake, Chika Kubota, Hiroshi Komatsu, Hirotaka Yamagata, Kenta Ide, Masahiro Takeshima, Mikio Kido, Saya Kikuchi, Tsuyoshi Okada, Junya Matsumoto, Kenichiro Miura, Taichi Shimazu, Ken Inada, Koichiro Watanabe, Ryota Hashimoto Psychiatry and Clinical Neurosciences 77 (10), 559-568, 2023-09-08

...., the Guideline for Pharmacological Therapy of Schizophrenia and the Treatment Guidelines for Major Depressive Disorders, in Japan....

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Shindo, Ryota, Tanifuji, Takaki, 岡﨑, 賢志, 大塚, 郁夫, Shirai, Toshiyuki, 毛利, 健太朗, 蓬莱, 政, 菱本, 明豊 npj Aging 9 (1), 19-, 2023-09-06

...Major depressive disorder (MDD) is known to cause significant disability. Genome-wide DNA methylation (DNAm) profiles can be used to estimate biological aging and as epigenetic clocks....

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Po-Han Chou, Wen-Chun Liu, Shao-Cheng Wang, Wei-Hao Lin, Yi-Lun Chung, Chun-Hung Chang, Kuan-Pin Su Frontiers in Psychiatry 14 2023-08-16

...<jats:sec><jats:title>Introduction</jats:title><jats:p>The effects of repetitive transcranial magnetic stimulation (rTMS) on the left dorsolateral prefrontal cortex (DLPFC) in patients with major depressive...

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Risa Yokokawa Shibata, Ryuji Kubota, Kazunori Uenaka, Atsunori Kaibara, Toshihiro Wajima Drug Metabolism and Pharmacokinetics 51 100496-, 2023-08

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Róbert György Vida, Eszter Sághy, Richárd Bella, Sándor Kovács, Dalma Erdősi, Judit Józwiak-Hagymásy, Antal Zemplényi, Tamás Tényi, Péter Osváth, Viktor Voros BMC Psychiatry 23 (1), 2023-07-27

...Depressive Disorder (MDD); however, results are contradictory due to heterogeneity of the included studies....

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Bandu Raju, Lee Hyun Jeong, Lee Hyeong Min, Ha Tae Hyon, Lee Heon-Jeong, Kim Se Joo, Ha Kyooseob, Kim Kwang Pyo Mass Spectrometry 12 (1), A0123-A0123, 2023-07-06

...depressive disorder (MDD)....

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Zhe Li, Ting-Ting Wu, Yi-Ting Xiong, Xin-Yang Zhang, Yan-Ping Bao, Li-Bo Guo, Bao-Jie Han, Su-Xia Li, Yu-Feng Wang, Lin Lu, Xue-Qin Wang Frontiers in Psychiatry 14 2023-06-22

...<jats:sec><jats:title>Objective</jats:title><jats:p>This study aimed to explore both impairments in attention function in patients with major depressive disorder (MDD) and the efficacy of escitalopram...

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Ryuichi Yamazaki, Yuki Matsuda, Mari Oba, Hideki Oi, Shinsuke Kito BMC Psychiatry 23 (1), 2023-06-16

...depressive disorder (MDD), and its effectiveness in preventing relapse/recurrence of MDD has been explored....

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Noboru Matsumoto, Yoshifumi Takahashi, David John Hallford Journal of Behavior Therapy and Experimental Psychiatry 79 101822-, 2023-06

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毛利 彰宏, 長谷川 眞也, 國澤 和生, 齋藤 邦明, 鍋島 俊隆 日本薬理学雑誌 158 (3), 233-237, 2023-05-01

<p>うつ病の病態にはモノアミン仮説が提唱されており，抗うつ薬の主流が選択的セロトニン（5-HT）再取り込み阻害薬であることから，特に5-HT神経系の機能低下が広く受け入れられている．しかし，患者の約1/3は既存の抗うつ薬に対して難治性であるため，新しい創薬ターゲットに対する新規抗うつ薬の開発が求められている．トリプトファン（TRP）は5-HT経路だけでなくキヌレニン（KYN）経路においても代謝…

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衣斐 大祐 日本薬理学雑誌 158 (3), 229-232, 2023-05-01

<p>うつ病の約3～4割は，治療抵抗性うつ病とされている．治療抵抗性うつ病に対する治療薬として，NMDA型グルタミン酸受容体拮抗薬ケタミンの光学異性体「エスケタミン」が欧米の一部の国で使われ始めているが，抵抗性や副作用の点からその使用は制限されている．最近の臨床報告から，マジックマッシュルームに含まれる幻覚成分である「シロシビン」が治療抵抗性うつ病患者に対し，即効かつ持続的な治療効果を示すことが…

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角谷, 寛, 山田, 尚登, NAKAJIMA, Suguru, KANEKO, Yoshiyuki, FUJII, Nobukuni, KIZUKI, Jun, SAITOH, Kaori, NAGAO, Kentaro, KAWAMURA, Aoi, YOSHIIKE, Takuya, KADOTANI, Hiroshi, YAMADA, Naoto, UCHIYAMA, Makoto, KURIYAMA, Kenichi, SUZUKI, Masahiro Frontiers in psychiatry 14 2023-04-24

...Previous studies have found a close relationship between insomnia and depressive symptoms in major depressive disorder (MDD), and that actively improving insomnia heightens the improvement of depressive...

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Yosuke Sato, Go Okada, Satoshi Yokoyama, Naho Ichikawa, Masahiro Takamura, Yuki Mitsuyama, Ayaka Shimizu, Eri Itai, Hotaka Shinzato, Mitsuo Kawato, Noriaki Yahata, Yasumasa Okamoto Scientific Reports 13 (1), 2023-04-18

...depressive disorder, knowledge about the neural basis of StD remains limited....

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Hiroyuki Kimura, Shinichi Kishi, Hisashi Narita, Teruaki Tanaka, Tsuyoshi Okada, Daisuke Fujisawa, Naoko Sugita, Shun’ichi Noma, Yosuke Matsumoto, Ayako Ohashi, Hiroshi Mitsuyasu, Keizo Yoshida, Hiroaki Kawasaki, Katsuji Nishimura, Yasuhiro Ogura, Norio Ozaki BMC Gastroenterology 23 (1), 2023-04-05

...Comorbid psychiatric disorders in the 1006 recipients were insomnia (<jats:italic>N</jats:italic> = 107, 10.6%), delirium (<jats:italic>N</jats:italic> = 103, 10.2%), major depressive disorder (<jats:italic...

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Go Okada, Toshinori Yoshioka, Ayumu Yamashita, Eri Itai, Satoshi Yokoyama, Toshiharu Kamishikiryo, Hotaka Shinzato, Yoshikazu Masuda, Yuki Mitsuyama, Shigeyuki Kan, Akiko Kurata, Masahiro Takamura, Atsuo Yoshino, Akio Mantani, Osamu Yamamoto, Norio Yokota, Tatsuji Tamura, Hiroaki Jitsuiki, Mitsuo Kawato, Okito Yamashita, Yuki Sakai, Yasumasa Okamoto Journal of Affective Disorders 326 262-266, 2023-04

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Takaki Tanifuji, Satoshi Okazaki, Ikuo Otsuka, Kentaro Mouri, Tadasu Horai, Ryota Shindo, Toshiyuki Shirai, Akitoyo Hishimoto Psychiatry Research 322 115103-, 2023-04

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Yuko Nakamura, Takuya Ishida, Saori C. Tanaka, Yuki Mitsuyama, Satoshi Yokoyama, Hotaka Shinzato, Eri Itai, Go Okada, Yuko Kobayashi, Takahiko Kawashima, Jun Miyata, Yujiro Yoshihara, Hidehiko Takahashi, Ryuta Aoki, Motoaki Nakamura, Haruhisa Ota, Takashi Itahashi, Susumu Morita, Shintaro Kawakami, Osamu Abe, Naohiro Okada, Akira Kunimatsu, Ayumu Yamashita, Okito Yamashita, Hiroshi Imamizu, Jun Morimoto, Yasumasa Okamoto, Toshiya Murai, Ryu‐Ichiro Hashimoto, Kiyoto Kasai, Mitsuo Kawato, Shinsuke Koike Psychiatry and Clinical Neurosciences 77 (6), 345-354, 2023-03-30

...However, the common and disease‐specific alterations remain to be examined in schizophrenia (SCZ), major depressive disorder (MDD), and autism spectrum disorder (ASD)....

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大島 裕子 産業精神保健 31 (1), 57-61, 2023-03-30

<p>REBT（Rational Emotive Behavior Therapy）は認知行動療法の主要な心理療法として有名であるが，治療効果はあまり知られていない．そこで本論では，大うつ病性障害（MDD: Major Depression Disorder）に関する代表的な介入研究，介入研究のメタ分析，さらにビリーフと抑うつの関係についてのメタ分析の概要を紹介する．REBTはMDDのマニュアル…

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Hirotaka Shoji, Kazutaka Ikeda, Tsuyoshi Miyakawa Molecular Brain 16 (1), 2023-03-29

...These phenotypes of 5-HTT−/− mice partially recapitulate clinical observations in humans with major depressive disorder....

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永井, 佑茉, 木坂, 優里, 野村, 健人, 西谷, 直也, 安藤, 千紘, 好田, 匡志, 河合, 洋幸, 勢力, 薫, 永安, 一樹, 笠井, 淳司, 白川, 久志, 中澤, 敬信, 橋本, 均, 金子, 周司 Cell Reports 42 (3), 112149-, 2023-03-28

...Major depressive disorder (MDD) is among the most common mental illnesses. Serotonergic (5-HT) neurons are central to the pathophysiology and treatment of MDD....

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Takuya Ishida, Yuko Nakamura, Saori C Tanaka, Yuki Mitsuyama, Satoshi Yokoyama, Hotaka Shinzato, Eri Itai, Go Okada, Yuko Kobayashi, Takahiko Kawashima, Jun Miyata, Yujiro Yoshihara, Hidehiko Takahashi, Susumu Morita, Shintaro Kawakami, Osamu Abe, Naohiro Okada, Akira Kunimatsu, Ayumu Yamashita, Okito Yamashita, Hiroshi Imamizu, Jun Morimoto, Yasumasa Okamoto, Toshiya Murai, Kiyoto Kasai, Mitsuo Kawato, Shinsuke Koike Schizophrenia Bulletin 49 (4), 933-943, 2023-03-09

...depressive disorder (MDD), and bipolar disorder (BD), to compare the causal relationships among the large-scale networks, including visual network, somatomotor network (SMN), dorsal attention network...

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谷藤, 貴紀, 大塚, 郁夫, Atarashiya, Toshio, 木村, 敦, 蓬莱, 政, 岡﨑, 賢志, 菱本, 明豊 Psychiatry and Clinical Neurosciences Reports 2 (1), e84-, 2023-03

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中川 伸, 陳 冲, 萩原 康輔, 平田 圭子, 藤井 優子 デサントスポーツ科学 44 (0), 67-75, 2023-02-22

<p>うつ病の薬物療法，精神療法などが進歩し一定の効果を示してきている．しかし，無効な患者が多く存在し，日常生活や社会生活の障害を改善するためには未だ不十分であるため，実臨床では補完療法などの開発，改良が重要になってきている．本研究では，心肺運動負荷検査 （Cardiopulmonary Exercise Test, CPX） …

DOI 医中誌

Kenji Hashimoto European Archives of Psychiatry and Clinical Neuroscience 273 (7), 1513-1525, 2023-02-14

...<jats:title>Abstract</jats:title><jats:p>Cognitive impairment has been observed in patients with various psychiatric disorders, including schizophrenia, major depressive disorder (MDD), and bipolar disorder...

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Minori Machida, Kaho Tanobe, Steve K. Lee, Shintaro Hara, Hiroaki Kumano, Jun Tayama Japanese Psychological Research 2023-01-25

...., generalized anxiety disorder, major depression disorder)....

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Mizuki Amano, Nariko Katayama, Satoshi Umeda, Yuri Terasawa, Hajime Tabuchi, Toshiaki Kikuchi, Takayuki Abe, Masaru Mimura, Atsuo Nakagawa Frontiers in Psychiatry 14 2023-01-25

...A randomized clinical trial (RCT) was conducted with patients diagnosed with major depressive disorder (MDD) to determine whether receiving a course of CBT affects pessimistic future thinking using a future...

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Go Okada, Yuki Sakai, Maki Shibakawa, Toshinori Yoshioka, Eri Itai, Hotaka Shinzato, Osamu Yamamoto, Kenichi Kurata, Tatsuji Tamura, Hiroaki Jitsuiki, Hidehisa Yamashita, Akio Mantani, Norio Yokota, Mitsuo Kawato, Yasumasa Okamoto BMC Psychiatry 23 (1), 2023-01-24

...<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Although many studies have reported the biological basis of major depressive disorder...

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Hiroshi Arinami, Yuichiro Watanabe, Yutaro Suzuki, Misuzu Tajiri, Nobuto Tsuneyama, Toshiyuki Someya Scientific Reports 13 (1), 2023-01-20

...<jats:title>Abstract</jats:title><jats:p>The pathophysiology underlying major depressive disorder (MDD) and schizophrenia is related to endocrine system functions and includes changes in the blood levels...

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Yamagata, Hirotaka, Tsunedomi, Ryouichi, Kamishikiryo, Toshiharu, Kobayashi, Ayumi, Seki, Tomoe, Kobayashi, Masaaki, Hagiwara, Kosuke, Yamada, Norihiro, Chen, Chong, Uchida, Shusaku, Ogihara, Hiroyuki, Hamamoto, Yoshihiko, Okada, Go, Fuchikami, Manabu, Iga, Jun-ichi, Numata, Shusuke, Kinoshita, Makoto, Kato, Takahiro A., Hashimoto, Ryota, Nagano, Hiroaki, Ueno, Shuichi, Okamoto, Yasumasa, Ohmori, Tetsuro, Nakagawa, Shin Heliyon 9 (1), e13059-, 2023-01-16

...We retrospectively divided patients with major depressive disorder into antidepressant responder and non-responder groups....

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Koki Takagaki, Satoshi Yokoyama Behavioral Sciences 13 (1), 72-, 2023-01-13

...Furthermore, subthreshold depression carries a risk for the subsequent development of major depressive disorder (MDD)....

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渡邉, 啓太, Okamoto, Naomichi, Ueda, Issei, Tesen, Hirofumi, Fujii, Rintaro, Ikenouchi, Atsuko, Yoshimura, Reiji, Kakeda, Shingo Brain Communications 5 (1), 2023

...In addition, we found novel bilateral networks in the hippocampus that were disturbed in patients with major depressive disorders, and these bilateral networks could predict major depressive disorders....

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川島, 啓嗣, 山崎, 真平, 久保田, 学, 挾間, 雅章, 伏見, 育崇, 宮田, 淳, 村井, 俊哉, 諏訪, 太朗 NeuroImage: Clinical 38 2023

...[Method] Twenty-nine Japanese participants, including 18 inpatients with major depressive disorder and 11 with schizophrenia, underwent longitudinal voxel-based morphometry before and after ECT....

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Tomita Ryoko, Hayama Tadashi, Nishijo Nao, Sogawa Rintaro, Shimanoe Chisato, Fujioka Toshihiro ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 71 (1), 10-14, 2023-01-01

...depressive disorder, in human plasma sample....

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吾郷 由希夫, 浅野 智志 日本薬理学雑誌 158 (1), 35-38, 2023

<p>うつ病は，抑うつ気分や，興味または喜びの著しい喪失を主症状とする精神疾患である．齧歯類を用いたうつ病の病態研究や創薬研究では，強制水泳試験や尾懸垂試験といった行動学的手法が広く利用されているが，動物に対して強い身体的ストレスが加わるもので，厳密には動物の抑うつ状態だけではなくストレス抵抗性の要素も評価結果に含まれている．意欲低下は，うつ病を含む精神疾患の重要な指標であり，我々は，マウスにお…

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坂田 昂駿, 毛利 彰宏, 國澤 和生, 長谷川 眞也, 西川 貴也, 竹村 正男, 松波 英寿, 齋藤 邦明, 鍋島 俊隆 日本薬理学会年会要旨集 97 (0), 2-B-SS09-5-, 2023

...</p><p>We analyzed lifestyle habits in high-risk subjects of major depressive disorder (HRMDD). In our analysis of lifestyle habits in HRMDD, we observed elevated sucrose intake....

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柴垣 郁弥 ファルマシア 59 (8), 777-777, 2023

...大うつ病性障害(Major Depression Disorders: MDD)は，ストレスが原因で発症し，不安や抑うつが引き起こされる精神神経疾患である．MDDの治療には抗うつ薬が使用されるが，奏効率が低いため，非薬物療法や予防法が研究されている．なかでも，適度な運動は多くの病気の発症を防ぐことから，運動によるMDDの改善が着目されている．運動は有酸素運動とレジスタンス運動(Resistance...

DOI

INOMATA TAKENORI, SUNG JAEMYOUNG, YEE ALAN, MURAKAMI AKIRA, OKUMURA YUICHI, NAGINO KEN, FUJIO KENTA, AKASAKI YASUTSUGU, MIDORIKAWA-INOMATA AKIE, EGUCHI ATSUKO, FUJIMOTO KEIICHI, HUANG TIANXIANG, MOROOKA YUKI, MIURA MARIA, SHOKIROVA HURRAMHON, HIROSAWA KUNIHIKO, OHNO MIZU, KOBAYASHI HIROYUKI 順天堂醫事雑誌 69 (1), 2-13, 2023

...The studies to date aided in determining the risk factors for severe dry eye, the association between major depressive disorder and dry eye exacerbation, eye drop treatment adherence, app-based stratification...

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吉岡 寿倫, 山田 大輔, 斎藤 顕宜 日本薬理学会年会要旨集 97 (0), 1-B-S13-3-, 2023

...<p>Psychological stress is a major cause of mental disorders such as major depressive disorder and anxiety disorder....

DOI Web Site

椿 美智博, 長島 享史, 辻本 陽子, 安斎 亨, 小泉 秀子, 伊東 由康 日本救急医学会関東地方会雑誌 43 (4), 121-126, 2022-12-28

<p>新型コロナウイルス感染症の流行下において, 医療体制の最前線を担う救急・集中治療領域に所属する看護師のメンタルヘルスは重要な支援課題である。本研究は救急・集中治療領域に所属する看護師が求める政策支援とメンタルヘルスを明らかにする。2021年4月に神奈川県の医療機関に所属する看護師を対象にWeb調査を実施した。調査では, …

DOI 医中誌

Kyou, Yoshitaka, Yasui‑Furukori, Norio, Hasegawa, Naomi, Ide, Kenta, Ichihashi, Kayo, Hashimoto, Naoki, Hori, Hikaru, Shimizu, Yoshihito, Imamura, Yayoi, Muraoka, Hiroyuki, Iida, Hitoshi, Ohi, Kazutaka, Yasuda, Yuka, Ogasawara, Kazuyoshi, Numata, Shusuke, Iga, Jun-ichi, Tsuboi, Takashi, Ochi, Shinichiro, Kodaka, Fumitoshi, Furihata, Ryuji, Onitsuka, Toshiaki, Makinodan, Manabu, Komatsu, Hiroshi, Takeshima, Masahiro, Kubota, Chika, Hishimoto, Akitoyo, Atake, Kiyokazu, Yamagata, Hirotaka, Kido, Mikio, Nagasawa, Tatsuya, Usami, Masahide, Kishimoto, Taishiro, Kikuchi, Saya, Matsumoto, Junya, Miura, Kenichiro, Yamada, Hisashi, Watanabe, Koichiro, Inada, Ken, Hashimoto, Ryota Annals of General Psychiatry 21 52-, 2022-12-26

...Background: Several guidelines recommend monotherapy in pharmacotherapy for schizophrenia and major depressive disorder....

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Yajun Yun, Qi Zhang, Wenxuan Zhao, Ting Ma, Hongzhen Fan, Luyuan Bai, Botao Ma, Siyuan Qi, Zhiren Wang, Huimei An, Fude Yang Journal of Psychosomatic Research 163 111069-, 2022-12

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Rastad Saber, Barjaste Nadia, Lanjanian Hossein, Moeini Ali, Kiani Farzad, Masoudi-nejad Ali Genes & Genetic Systems 97 (6), 311-324, 2022-12-01

...<p>Alzheimer’s disease (AD) and major depressive disorder (MDD) are comorbid neuropsychiatric disorders that are among the leading causes of long-term disability worldwide....

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Kangtao Wang, Fengbo Tan, Zhiming Zhu, Lingyu Kong Frontiers in Psychiatry 13 978763-, 2022-11-30

...<jats:sec><jats:title>Objective</jats:title><jats:p>This study aims to construct and use natural language processing and other methods to analyze major depressive disorder (MDD) and radiology studies’...

DOI Web Site 被引用文献1件

Iida, Hitoshi, Okada, Tsuyoshi, Nemoto, Kiyotaka, Hasegawa, Naomi, Numata, Shusuke, Ogasawara, Kazuyoshi, Miura, Kenichiro, Matsumoto, Junya, Hori, Hikaru, Iga, Jun-ichi, Ichihashi, Kayo, Hashimoto, Naoki, Yamada, Hisashi, Ohi, Kazutaka, Yasui-Furukori, Norio, Fukumoto, Kentaro, Tsuboi, Takashi, Usami, Masahide, Furihata, Ryuji, Takaesu, Yoshikazu, Hishimoto, Akitoyo, Muraoka, Hiroyuki, Katsumoto, Eiichi, Nagasawa, Tatsuya, Ochi, Shinichiro, Komatsu, Hiroshi, Kikuchi, Saya, Takeshima, Masahiro, Onitsuka, Toshiaki, Tamai, Shinichiro, Kubota, Chika, Inada, Ken, Watanabe, Koichiro, Kawasaki, Hiroaki, Hashimoto, Ryota Neuropsychopharmacology Reports 43 (1), 23-32, 2022-11-28

...The degree of satisfaction was similar for the courses on schizophrenia and major depressive disorder....

DOI 機関リポジトリ HANDLE ほか2件 参考文献14件

Kuniyoshi Toyoshima, Jiro Masuya, Miki Ono, Mina Honyashiki, Shogo Hashimoto, Ichiro Kusumi, Takeshi Inoue International Journal of Environmental Research and Public Health 19 (23), 15841-, 2022-11-28

...<jats:p>Depressive symptoms (DepS) associated with major depressive disorder (MDD) are influenced by affective temperaments (ATs), behavioral inhibition system (BIS), and behavioral activation system (...

DOI Web Site 参考文献47件

Krista J. Howard, Caleb Leong, Sidney Chambless, Timothy J. Grigsby, Millie Cordaro, Jessica K. Perrotte, Jeffrey T. Howard International Journal of Environmental Research and Public Health 19 (23), 15748-, 2022-11-26

...The present study’s aims were to: (1) examine the prevalence of major depressive disorder (MDD) in postpartum women during the COVID-19 pandemic, and (2) evaluate whether social support can buffer the...

DOI Web Site 被引用文献1件

Maki Komiyama, Yuka Ozaki, Hiromichi Wada, Hajime Yamakage, Noriko Satoh-Asahara, Akihiro Yasoda, Yoichi Sunagawa, Tatsuya Morimoto, Shinji Tamaki, Masahiro Suzuki, Takuo Shibayama, Toru Kato, Yasumasa Okada, Toshiyuki Kita, Yuko Takahashi, Koji Hasegawa BMC Complementary Medicine and Therapies 22 (1), 2022-11-25

...To examine the efficacy of Yokukansan during smoking cessation (SC) therapy in smokers with depressive tendencies but without major depressive disorders requiring pharmacotherapy....

DOI PDF Web Site 参考文献28件

Shinsuke Hidese, Fuyuko Yoshida, Ikki Ishida, Junko Matsuo, Kotaro Hattori, Hiroshi Kunugi Neuropsychopharmacology Reports 43 (1), 57-68, 2022-11-22

...depressive disorder (MDD), and 350 healthy controls....

DOI Web Site Web Site 参考文献61件

Ryo Shikimoto, Shoko Nozaki, Norie Sawada, Yoko Shimizu, Thomas Svensson, Atsuo Nakagawa, Masaru Mimura, Shoichiro Tsugane Journal of Alzheimer's Disease 90 (3), 1085-1101, 2022-11-22

...This association remained significant after adjusting for sex, age, education, diagnosis of current major depressive disorder, past history of ischemic heart disease, diabetes, regular alcohol consumption...

DOI Web Site 参考文献48件

Ye Li, Cuiqin Fan, Changmin Wang, Liyan Wang, Yuhang Yi, Xueqin Mao, Xiao Chen, Tian Lan, Wenjing Wang, Shu Yan Yu Science Advances 8 (45), 2022-11-11

...<jats:p> Major depression disorder (MDD) is a neuropsychiatric disorder characterized by abnormal neuronal activity in specific brain regions....

DOI Web Site 被引用文献1件

Takashi Tsuboi, Yoshikazu Takaesu, Naomi Hasegawa, Shinichiro Ochi, Kentaro Fukumoto, Kazutaka Ohi, Hiroyuki Muraoka, Tsuyoshi Okada, Funitoshi Kodaka, Shun Igarashi, Hitoshi Iida, Hiroko Kashiwagi, Hikaru Hori, Kayo Ichihashi, Kazuyoshi Ogasawara, Naoki Hashimoto, Jun‐ichi Iga, Toshinori Nakamura, Masahide Usami, Tatsuya Nagasawa, Mikio Kido, Hiroshi Komatsu, Hirotaka Yamagata, Kiyokazu Atake, Ryuji Furihata, Saya Kikuchi, Tadasu Horai, Masahiro Takeshima, Yoji Hirano, Manabu Makinodan, Junya Matsumoto, Kenichiro Miura, Akitoyo Hishimoto, Shusuke Numata, Hisashi Yamada, Norio Yasui‐Furukori, Ken Inada, Koichiro Watanabe, Ryota Hashimoto Psychiatry and Clinical Neurosciences 77 (1), 30-37, 2022-11-09

...<jats:sec><jats:title>Aim</jats:title><jats:p>We investigated the association of electroconvulsive therapy (ECT) with anxiolytic and sleep medication use in patients with major depressive disorder (MDD...

DOI Web Site Web Site 参考文献45件

Takaesu, Yoshikazu, Yuta, Kanda, Nagahama, Yu, Shiroma, Ayano, Ishii, Miho, Hashimoto, Tasuku, Watanabe, Koichiro Frontiers in Psychiatry 13 2022-11-07

...Background: The delayed sleep-wake phase is commonly observed in major depressive disorder (MDD) and thought to be associated with functional impairments....

DOI 機関リポジトリ HANDLE ほか1件 参考文献30件

Atul Kabra, Ruchika Garg, James Brimson, Jelena Živković, Saud Almawash, Muhammad Ayaz, Asif Nawaz, Syed Shams Ul Hassan, Simona Bungau Frontiers in Pharmacology 13 1046599-, 2022-11-07

...However, only about half of patients with major depressive disorder (MDD) respond effectively to first-line antidepressant therapy....

DOI Web Site 被引用文献1件

Katsuma Miyaho, Kenji Sanada, Shunya Kurokawa, Arisa Tanaka, Tomoyuki Tachibana, Chiharu Ishii, Yoshihiro Noda, Shinichiro Nakajima, Shinji Fukuda, Masaru Mimura, Taishiro Kishimoto, Akira Iwanami Journal of Personalized Medicine 12 (11), 1827-, 2022-11-03

...<jats:p>We aimed to investigate the impact of aging on the relationship among the composition of gut microbiota, gastrointestinal (GI) symptoms, and the course of treatment for major depressive disorder...

DOI Web Site 参考文献51件

Giovanni Pagni, Claudia Tagliarini, Manuel Glauco Carbone, Bruno Pietro Imbimbo, Donatella Marazziti, Nunzio Pomara Current Medicinal Chemistry 29 (36), 5731-5757, 2022-11

...Depressive Disorder or depressive symptoms evaluated with standard scales....

DOI Web Site Web Site 被引用文献1件

Hugo Bottemanne, Orphee Morlaas, Anne Claret, Tali Sharot, Philippe Fossati, Liane Schmidt JAMA Psychiatry 79 (11), 1124-, 2022-11-01

...Patients with TRD were diagnosed with major depressive disorder or bipolar depression, had a Montgomery-Åsberg Depression Rating Scale score greater than 20, a Maudsley Staging Method score greater than...

DOI PDF 被引用文献1件

Tomiki Sumiyoshi, Hiroyuki Uchida, Koichiro Watanabe, Masato Oosawa, Hongye Ren, Yoshiya Moriguchi, Keita Fujikawa, Jovelle Fernandez Neuropsychiatric Disease and Treatment Volume 18 2507-2517, 2022-11

DOI Web Site 被引用文献1件

Natsuko Ikeda, Shinichi Yamada, Kasumi Yasuda, Shinya Uenishi, Atsushi Tamaki, Takuya Ishida, Michiyo Tabata, Tomikimi Tsuji, Sohei Kimoto, Shun Takahashi Journal of Neuropsychology 17 (2), 351-363, 2022-10-28

...Subjects comprised 21 healthy controls, 19 patients with schizophrenia, 20 patients with bipolar disorder and 18 patients with major depressive disorder....

DOI Web Site Web Site 参考文献54件

Akiko Fujita, Kazushige Ihara, Hisashi Kawai, Shuichi Obuchi, Yutaka Watanabe, Hirohiko Hirano, Yoshinori Fujiwara, Yoichi Takeda, Masashi Tanaka, Keiko Kato Discover Mental Health 2 (1), 2022-10-27

...This study aimed to identify novel biomarkers of major depressive disorder (MDD) and anxiety in the elderly....

DOI PDF Web Site 参考文献74件

Erin R. Saito, Cali E. Warren, Cameron M. Hanegan, John G. Larsen, Johannes D. du Randt, Mio Cannon, Jeremy Y. Saito, Rachel J. Campbell, Colin M. Kemberling, Gavin S. Miller, Jeffrey G. Edwards, Benjamin T. Bikman Metabolites 12 (11), 1019-, 2022-10-25

...Ketones have been suggested as therapeutic for their efficacy in epilepsy and other brain pathologies such as Alzheimer’s disease and major depressive disorder....

DOI Web Site 被引用文献1件

Marina Hirose, Toru Nakamura, Akiko Watanabe, Yuichi Esaki, Shigefumi Koike, Yoshiharu Yamamoto, Nakao Iwata, Tsuyoshi Kitajima Frontiers in Psychiatry 13 2022-10-13

...Further, we found that the scaling exponents of resting period distributions significantly decreased in major depressive disorder (MDD)....

DOI Web Site 参考文献38件

Hiral Master, Jeffrey Annis, Shi Huang, Joshua A. Beckman, Francis Ratsimbazafy, Kayla Marginean, Robert Carroll, Karthik Natarajan, Frank E. Harrell, Dan M. Roden, Paul Harris, Evan L. Brittain Nature Medicine 28 (11), 2301-2308, 2022-10-10

...depressive disorder (<jats:italic>n</jats:italic> = 467), with values above 8,200 daily steps associated with protection from incident disease....

DOI PDF Web Site 被引用文献2件

Gabriel R. Fries, Valeria A. Saldana, Johannes Finnstein, Theo Rein Molecular Psychiatry 28 (1), 284-297, 2022-10-06

...<jats:title>Abstract</jats:title><jats:p>Major depressive disorder (MDD) is a psychiatric disease of still poorly understood molecular etiology....

DOI PDF Web Site 被引用文献1件

Xing Chen, Tongtong Zhang, Xiaoyan Shan, Qun Yang, Peiyun Zhang, Haijiao Zhu, Fei Jiang, Chao Liu, Yanzhong Li, Weijun Li, Jian Xu, Hongmei Shen Frontiers in Psychiatry 13 2022-10-03

...depression disorder (MDD) patients and to examine the improvement of HF-rTMS on cognitive impairment evoked by electroconvulsive therapy (ECT)....

DOI Web Site 被引用文献1件

Zui Narita, Shoko Nozaki, Ryo Shikimoto, Hiroaki Hori, Yoshiharu Kim, Masaru Mimura, Shoichiro Tsugane, Norie Sawada Translational Psychiatry 12 (1), 2022-09-26

...<jats:title>Abstract</jats:title><jats:p>We evaluated the association between vegetable and fruit consumption – particularly flavonoid-rich fruits – in mid-life and major depressive disorder (MDD) in later...

DOI PDF Web Site 参考文献44件

Shinichiro Ochi, Takaaki Mori, Jun-ichi Iga, Shu-ichi Ueno Journal of Alzheimer's Disease Reports 6 (1), 589-598, 2022-09-24

...Objective: We aimed to investigate the prevalence of dementia in patients with late-life major depressive disorder (MDD) or bipolar disorder (BD) and to clarify the clinical characteristics associated...

DOI Web Site 参考文献57件

Aleksandra Góralczyk-Bińkowska, Dagmara Szmajda-Krygier, Elżbieta Kozłowska International Journal of Molecular Sciences 23 (19), 11245-, 2022-09-24

...We review the microbiota alterations and their results in the development of psychiatric disorders, including major depressive disorder (MDD), schizophrenia (SCZ), bipolar disorder (BD), autism spectrum...

DOI Web Site 被引用文献1件

Yuko Toshishige, Masaki Kondo, Junya Okazaki, Hiroko Mizushima, Tatsuo Akechi Case Reports in Psychiatry 2022 1-7, 2022-09-19

...<jats:p>Bereavement-related major depressive disorder (MDD) is a common disorder with both mental and physical effects....

DOI PDF XML 参考文献18件

Maiko Satomoto Ketamine Revisited - New Insights into NMDA Inhibitors 2022-09-14

...<jats:p>Electroconvulsive therapy (ECT) is highly effective both Major Depressive Disorder (MDD) and Bipolar Disorder (BD)....

DOI Web Site 参考文献42件

Masakazu Higuchi, Mitsuteru Nakamura, Shuji Shinohara, Yasuhiro Omiya, Takeshi Takano, Daisuke Mizuguchi, Noriaki Sonota, Hiroyuki Toda, Taku Saito, Mirai So, Eiji Takayama, Hiroo Terashi, Shunji Mitsuyoshi, Shinichi Tokuno International Journal of Environmental Research and Public Health 19 (18), 11397-, 2022-09-10

...Lastly, the proposed metric could serve as a new measure for evaluation of major depressive disorder.</jats:p>...

DOI Web Site 参考文献33件

Maxime Richard, Clémence Noiseux, Véronique Desbeaumes Jodoin, Daniel M. Blumberger, Jack Sheen, Farrokh Mansouri, Laurent Elkrief, Christophe Longpré-Poirier, Paul Lespérance, Jean-Philippe Miron Psychiatry Research 315 114709-, 2022-09

DOI Web Site Web Site 被引用文献1件

Dominik Kriesche, Christian F. J. Woll, Nadja Tschentscher, Rolf R. Engel, Susanne Karch European Archives of Psychiatry and Clinical Neuroscience 273 (5), 1105-1128, 2022-09-01

...<jats:title>Abstract</jats:title><jats:p>Previous research suggests a broad range of deficits in major depressive disorder....

DOI PDF Web Site 被引用文献1件

Fabian Schumacher, Alexander Carpinteiro, Michael J. Edwards, Gregory C. Wilson, Simone Keitsch, Matthias Soddemann, Barbara Wilker, Burkhard Kleuser, Katrin Anne Becker, Christian P. Müller, Johannes Kornhuber, Erich Gulbins Journal of Molecular Medicine 100 (10), 1493-1508, 2022-08-31

...<jats:sec> <jats:title>Abstract</jats:title> <jats:p>Major depressive disorder (MDD) is a very common, severe disease with a lifetime prevalence of ~ 10%....

DOI PDF Web Site 被引用文献1件

Weiping Dai, Mengqian Yang, Pei Xia, Chuan Xiao, Shuying Huang, Zhan Zhang, Xin Cheng, Wenchang Li, Jian Jin, Jingyun Zhang, Binghuo Wu, Yingying Zhang, Pei-hui Wu, Yangyang Lin, Wen Wu, Hu Zhao, Yan Zhang, Wei-Jye Lin, Xiaojing Ye Nature Communications 13 (1), 2022-08-16

...<jats:title>Abstract</jats:title><jats:p>Major depressive disorder is one of the most common mental health conditions....

DOI PDF Web Site 被引用文献1件

Takaesu, Yoshikazu, Aoki, Yumi, Tomo, Yui, Tsuboi, Takashi, Ishii, Miho, Imamura, Yayoi, Tachimori, Hisateru, Watanabe, Koichiro Frontiers in Psychiatry 13 2022-08-12

...The aim of this study was to assess whether a shared decision-making (SDM) training program for clinicians based on the major depressive disorder (MDD) guidelines improved the perceived involvement of...

DOI 機関リポジトリ HANDLE ほか1件 参考文献31件

Damien Prouzeau, Ismaël Conejero, Peter L. Voyvodic, Carine Becamel, Mocrane Abbar, Jorge Lopez-Castroman Current Psychiatry Reports 24 (10), 573-581, 2022-08-12

DOI PDF Web Site 被引用文献1件

Aet O’Leary, Noèlia Fernàndez-Castillo, Gabriela Gan, Yunbo Yang, Anna Y. Yotova, Thorsten M. Kranz, Lena Grünewald, Florian Freudenberg, Ester Antón-Galindo, Judit Cabana-Domínguez, Anais Harneit, Janina I. Schweiger, Kristina Schwarz, Ren Ma, Junfang Chen, Emanuel Schwarz, Marcella Rietschel, Heike Tost, Andreas Meyer-Lindenberg, Christiane A. Pané-Farré, Tilo Kircher, Alfons O. Hamm, Demian Burguera, Nina Roth Mota, Barbara Franke, Susann Schweiger, Jennifer Winter, Andreas Heinz, Susanne Erk, Nina Romanczuk-Seiferth, Henrik Walter, Andreas Ströhle, Lydia Fehm, Thomas Fydrich, Ulrike Lueken, Heike Weber, Thomas Lang, Alexander L. Gerlach, Markus M. Nöthen, Georg W. Alpers, Volker Arolt, Stephanie Witt, Jan Richter, Benjamin Straube, Bru Cormand, David A. Slattery, Andreas Reif Molecular Psychiatry 27 (11), 4464-4473, 2022-08-10

...disorder and schizophrenia....

DOI PDF Web Site 被引用文献1件

Xiangdong Du, Siyun Zou, Yan Yue, Xiaojia Fang, Yuxuan Wu, Siqi Wu, Haitao Wang, Zhe Li, Xueli Zhao, Ming Yin, Gang Ye, Hongyan Sun, Xiaochu Gu, Xiaobin Zhang, Zhigang Miao, Jeff Wang Jin, Hanjing Emily Wu, Yansong Liu, Xingshun Xu BMC Psychiatry 22 (1), 2022-08-05

...<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Interleukin-18 (IL-18) may participate in the development of major depressive disorder...

DOI PDF Web Site 被引用文献1件

Kazuhiro Ishikawa, Kiyotaka Nemoto, Yuki Shiratori, Noriko Sodeyama, Kikuko Kodama, Hitoshi Usuniwa, Noriko Yamada, Chie Yaguchi, Takafumi Hori, Tetsuaki Arai, Hirokazu Tachikawa Psychiatry and Clinical Neurosciences Reports 1 (3), 2022-08-03

...</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The subjects were 29 patients with major depressive disorder, nine of whom had attempted suicide....

DOI Web Site Web Site ほか1件 参考文献55件

Takehiro Tamura, Genichi Sugihara, Kyoji Okita, Yohei Mukai, Hiroshi Matsuda, Hiroki Shiwaku, Shunsuke Takagi, Hiromitsu Daisaki, Ukihide Tateishi, Hidehiko Takahashi Translational Psychiatry 12 (1), 2022-08-03

...We performed SPECT using <jats:sup>123</jats:sup>I-ioflupane to measure DAT binding in 150 patients with major depressive disorder (<jats:italic>N</jats:italic> = 112) and bipolar disorder (<jats:italic...

DOI PDF Web Site 参考文献44件

Fujika Katsuki, Norio Watanabe, Atsurou Yamada, Takaaki Hasegawa BJPsych Open 8 (5), 2022-08-02

...depressive disorder (MDD)....

DOI Web Site 参考文献63件

Muraoka, Hiroyuki, Kodaka, Fumitoshi, Hasegawa, Naomi, Yasui-Furukori, Norio, Fukumoto, Kentaro, Kashiwagi, Hiroko, Tagata, Hiromi, Hori, Hikaru, Atake, Kiyokazu, Iida, Hitoshi, Ichihashi, Kayo, Furihata, Ryuji, Tsuboi, Takashi, Takeshima, Masahiro, Komatsu, Hiroshi, Kubota, Chika, Ochi, Shinichiro, Takaesu, Yoshikazu, Usami, Masahide, Nagasawa, Tatsuya, Makinodan, Manabu, Nakamura, Toshinori, Kido, Mikio, Ueda, Ikki, Yamagata, Hirotaka, Onitsuka, Toshiaki, Asami, Takeshi, Hishimoto, Akitoyo, Ogasawara, Kazuyoshi, Katsumoto, Eiichi, Miura, Kenichiro, Matsumoto, Junya, Ohi, Kazutaka, Yamada, Hisashi, Watanabe, Koichiro, Inada, Ken, Nishimura, Katsuji, Hashimoto, Ryota Asian Journal of Psychiatry 74 103174-, 2022-08

...Purpose: In the treatment guidelines for major depressive disorder (MDD), the recommended treatment differs based on the severity....

DOI 機関リポジトリ HANDLE ほか2件 被引用文献3件 参考文献20件

Fabian Schumacher, Michael J. Edwards, Christiane Mühle, Alexander Carpinteiro, Greg C. Wilson, Barbara Wilker, Matthias Soddemann, Simone Keitsch, Norbert Scherbaum, Bernhard W. Müller, Undine E. Lang, Christoph Linnemann, Burkhard Kleuser, Christian P. Müller, Johannes Kornhuber, Erich Gulbins Journal of Biological Chemistry 298 (8), 102185-, 2022-08

DOI Web Site Web Site 被引用文献1件

Audrey G. Evers, James W. Murrough, Dennis S. Charney, Sara Costi Frontiers in Psychiatry 13 2022-07-28

...<jats:p>Stress exposure is one of the greatest risk factors for psychiatric illnesses, including major depressive disorder (MDD) and posttraumatic stress disorder (PTSD)....

DOI Web Site 被引用文献1件

Nuojin Li, Tian Zhou, Erkang Fei International Journal of Molecular Sciences 23 (15), 8281-, 2022-07-27

...depressive disorder (MDD), Alzheimer’s disease (AD) and Fragile X syndrome (FXS); however, the mechanism underlying metformin in the brain is not fully understood....

DOI Web Site 被引用文献1件

Zaiquan Dong, Xiaoling Shen, Yanni Hao, Jin Li, Haizhen Xu, Li Yin, Weihong Kuang Frontiers in Neuroscience 16 2022-07-22

...<jats:p>The therapeutic outcomes in major depressive disorder (MDD), one of the most common and heterogeneous mental illnesses, are affected by factors that remain unclear and often yield unsatisfactory...

DOI Web Site 被引用文献1件

Yuanxi Li, Bing Zhang, Xiaochuan Pan, Yihong Wang, Xuying Xu, Rubin Wang, Zhiqiang Liu Frontiers in Cellular Neuroscience 16 923039-, 2022-07-22

...<jats:p>Major depressive disorder (MDD) is a serious psychiatric disorder, with an increasing incidence in recent years....

DOI Web Site 被引用文献1件

Rajeev Joshi, Stephen R. J. Salton Frontiers in Molecular Neuroscience 15 932497-, 2022-07-15

...depressive disorder (MDD) and Alzheimer’s disease (AD)....

DOI Web Site 被引用文献1件

Alessandra Alciati, Angelo Reggiani, Daniela Caldirola, Giampaolo Perna 2022-07-14

...Here, we review the use of iPSC technology to model and potentially treat neuropsychiatric disorders by illustrating the key studies on a series of mental disorders, including schizophrenia, major depression...

DOI 被引用文献1件

Marian Lueno, Henrik Dobrowolny, Dorothee Gescher, Laila Gbaoui, Gabriele Meyer-Lotz, Christoph Hoeschen, Thomas Frodl Frontiers in Psychiatry 13 2022-07-12

...<jats:p>Major depressive disorder (MDD) is a widespread common disorder. Up to now, there are no easy and frequent to use non-invasive biomarkers that could guide the diagnosis and treatment of MDD....

DOI Web Site 被引用文献1件

Ines Chendo, Carlos Silva, Gonçalo S. Duarte, Luisa Prada, João Vian, Ana Quintão, Valerie Voon, Joaquim J. Ferreira Journal of Parkinson's Disease 12 (5), 1409-1418, 2022-07-08

...Mean baseline PD duration and major depressive disorder frequency were positively correlated.</jats:p>...

DOI Web Site 被引用文献1件

Aoki, Yumi, Takaesu, Yoshikazu, Baba, Hajime, Iga, Jun-ichi, Hori, Hikaru, Inoue, Takeshi, Mishima, Kazuo, Tajika, Aran, Kato, Masaki Neuropsychopharmacology Reports 42 (3), 306-314, 2022-07-01

...Aim: While evidence-based antidepressant treatment is available for major depressive disorder, standard approaches for discontinuation of antidepressants after remission have not yet been established....

DOI 機関リポジトリ HANDLE ほか3件 被引用文献1件 参考文献32件

Herriot Tabuteau, Amanda Jones, Ashley Anderson, Mark Jacobson, Dan V. Iosifescu American Journal of Psychiatry 179 (7), 490-499, 2022-07-01

DOI Web Site 被引用文献1件

C. Sophia Albott, Kelvin O. Lim, Christopher Erbes, Paul Thuras, Joseph Wels, Susanna J. Tye, Paulo R. Shiroma Journal of Affective Disorders 308 289-297, 2022-07

DOI Web Site Web Site 被引用文献1件

Maki Umeda, Norito Kawakami, Haruki Shimoda, Karin Miyamoto, Hanako Ishikawa, Hisateru Tachimori, Tadashi Takeshima Psychiatry and Clinical Neurosciences Reports 1 (3), 2022-06-30

...</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Risk for major depressive disorders were three to four times higher in an early‐menarche group, and the differences in survival functions...

DOI Web Site Web Site 参考文献40件

Yuka Shirakawa, Ryuichi Yamazaki, Yosuke Kita, Yuzuki Kitamura, Yasuko Okumura, Yuki Inoue, Yuki Matsuda, Fumitoshi Kodaka, Masahiro Shigeta, Shinsuke Kito NeuroReport 33 (11), 470-475, 2022-06-27

...<jats:p>Patients with major depressive disorder (MDD) exhibit several clinical symptoms including difficulties in flexible thinking....

DOI Web Site 参考文献23件

Nobuyuki Kobayashi, Shunichiro Shinagawa, Tomoyuki Nagata, Masahiro Shigeta, Kazuhiro Kondo Journal of Personalized Medicine 12 (7), 1040-, 2022-06-25

...<jats:p>There is strong evidence for an association between major depressive disorder (MDD) and inflammation....

DOI Web Site 参考文献33件

Man-Man Zhang, Min-Xia Guo, Qiu-Ping Zhang, Xue-Qin Chen, Na-Zhi Li, Qing Liu, Jie Cheng, Shi-Le Wang, Guang-Hui Xu, Cheng-Fu Li, Ji-Xiao Zhu, Li-Tao Yi Cell & Bioscience 12 (1), 2022-06-17

...<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Major depressive disorder is characterized by not only monoamine neurotransmitters...

DOI PDF Web Site 被引用文献1件

Tsutomu Takahashi, Daiki Sasabayashi, Murat Yücel, Sarah Whittle, Valentina Lorenzetti, Mark Walterfang, Michio Suzuki, Christos Pantelis, Gin S. Malhi, Nicholas B. Allen Frontiers in Human Neuroscience 16 917270-, 2022-06-13

...depressive disorder (MDD)....

DOI Web Site 被引用文献1件 参考文献68件

Paulo R. Shiroma, Mario Renato Velit-Salazar, Yelena Vorobyov Clinical Drug Investigation 42 (7), 549-566, 2022-06-07

DOI PDF Web Site 被引用文献1件

Haixia Wang, Yi He, Zuoli Sun, Siyu Ren, Mingxia Liu, Gang Wang, Jian Yang Journal of Neuroinflammation 19 (1), 132-, 2022-06-06

...<jats:title>Abstract</jats:title><jats:p>Major depressive disorder is a highly debilitating psychiatric disorder involving the dysfunction of different cell types in the brain....

DOI PDF Web Site 被引用文献1件

Chika Sumiyoshi, Kazutaka Ohi, Haruo Fujino, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Yota Uno, Junichi Takahashi, Kentaro Morita, Asuka Katsuki, Maeri Yamamoto, Yuko Okahisa, Ayumi Sata, Eiichi Katsumoto, Michihiko Koeda, Yoji Hirano, Masahito Nakataki, Junya Matsumoto, Kenichiro Miura, Naoki Hashimoto, Manabu Makinodan, Tsutomu Takahashi, Kiyotaka Nemoto, Toshifumi Kishimoto, Michio Suzuki, Tomiki Sumiyoshi, Ryota Hashimoto BJPsych Open 8 (4), 2022-06-03

...depression disorder or autism spectrum disorder and 1030 healthy control subjects were recruited from facilities in various regions of Japan....

DOI Web Site 参考文献41件

岡田, 知久, 藤本, 晃司, 伏見, 育崇, 赤坂, 太, Thuy, Dinh H. D., 島, 淳, 澤本, 伸克, 大石, 直也, Zhang, Zhilin, 舟木, 健史, 中本, 裕士, 村井, 俊哉, 宮本, 享, 髙橋, 良輔, 伊佐, 正 Quantitative Imaging in Medicine and Surgery 12 (6), 3406-3435, 2022-06-01

...depressive disorder, and schizophrenia....

DOI HANDLE Web Site

Mate Abraham, Annakarina Mundorf, Katja Brodmann, Nadja Freund Brain and Behavior 12 (7), e2629-, 2022-06

...depressive disorder, as well as on rodents and primates subjected to an animal model of depression....

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Ilya Demchenko, Vanessa K. Tassone, Sidney H. Kennedy, Katharine Dunlop, Venkat Bhat Frontiers in Psychiatry 13 864902-, 2022-05-26

...<jats:p>Conventional monoamine-based pharmacotherapy, considered the first-line treatment for major depressive disorder (MDD), has several challenges, including high rates of non-response....

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Ning Sun, Jie Zhang, Jizhi Wang, Zhifen Liu, Xin Wang, Pengli Kang, Chunxia Yang, Penghong Liu, Kerang Zhang Psychiatry and Clinical Neurosciences 76 (7), 321-328, 2022-05-23

...<jats:sec><jats:title>Aim</jats:title><jats:p>Gut microbiota and its metabolite bile acids may play a significant role in the occurrence and development of major depressive disorder (MDD)....

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Yosuke Koshikawa, Keiichiro Nishida, Tomonari Yamane, Masafumi Yoshimura, Ai Onohara, Satsuki Ueda, Ryouhei Ishii, Toshihiko Kinoshita, Yosuke Morishima Psychiatry and Clinical Neurosciences 76 (7), 329-337, 2022-05-14

...<jats:sec><jats:title>Background</jats:title><jats:p>Cognitive dysfunction is a persistent residual symptom in major depressive disorders (MDDs) that hinders social and occupational recovery....

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Kamishikiryo, Toshiharu, Okada, Go, Itai, Eri, Masuda, Yoshikazu, Yokoyama, Satoshi, Takamura, Masahiro, Fuchikami, Manabu, Yoshino, Atsuo, Mawatari, Kazuaki, Numata, Shusuke, Takahashi, Akira, Ohmori, Tetsuro, Okamoto, Yasumasa Psychiatry and Clinical Neurosciences 76 (8), 367-376, 2022-05-11

...depressive disorder in response to escitalopram treatment....

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Zhifei Li, Roger S. McIntyre, Syeda F. Husain, Roger Ho, Bach X. Tran, Hien Thu Nguyen, Shuenn-Chiang Soo, Cyrus S. Ho, Nanguang Chen eBioMedicine 79 104027-, 2022-05

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Jenny Borkent, Magdalini Ioannou, Jon D. Laman, Bartholomeus C. M. Haarman, Iris E. C. Sommer Psychological Medicine 52 (7), 1222-1242, 2022-05

...<jats:title>Abstract</jats:title><jats:p>Major depressive disorder (MDD), bipolar disorder (BD) and schizophrenia-spectrum disorders (SSD) are heterogeneous psychiatric disorders, which place significant...

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森下, 千尋, 桝屋, 二郎, 市来, 真彦, 井上, 猛 東京医科大学雑誌 80 (2), 133-, 2022-04-30

機関リポジトリ 医中誌

Yamada, Hisashi, Motoyama, Mikuni, Hasegawa, Naomi, Miura, Kenichiro, Matsumoto, Junya, Ohi, Kazutaka, Yasui-Furukori, Norio, Numata, Shusuke, Takeshima, Masahiro, Sugiyama, Nobuhiro, Nagasawa, Tatsuya, Kubota, Chika, Atake, Kiyokazu, Tsuboi, Takashi, Ichihashi, Kayo, Hashimoto, Naoki, Inagaki, Takahiko, Takaesu, Yoshikazu, Iga, Jun-Ichi, Hori, Hikaru, Onitsuka, Toshiaki, Komatsu, Hiroshi, Hishimoto, Akitoyo, Fukumoto, Kentaro, Fujimoto, Michiko, Nakamura, Toshinori, Nemoto, Kiyotaka, Furihata, Ryuji, Yamamura, Satoshi, Yamagata, Hirotaka, Ogasawara, Kazuyoshi, Katsumoto, Eiichi, Murata, Atsunobu, Iida, Hitoshi, Ochi, Shinichiro, Makinodan, Manabu, Kido, Mikio, Kishimoto, Taishiro, Yasuda, Yuka, Usami, Masahide, Suwa, Taro, Inada, Ken, Watanabe, Koichiro, Hashimoto, Ryota BJPsych Open 8 (3), e83-, 2022-04-21

...Background Clinical practice guidelines for schizophrenia and major depressive disorder have been published. However, these have not had sufficient penetration in clinical settings....

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David John Hallford, Noboru Matsumoto International Journal of Psychology 57 (5), 577-584, 2022-04-16

...<jats:p>Major depressive disorder (MDD) is associated with reduced specificity in autobiographical memory....

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Kento Ogawa, Kokoro Shirai, Shoko Nozaki, Ryo Shikimoto, Norie Sawada, Masaru Mimura, Hiroyasu Iso, Shoichiro Tsugane Translational Psychiatry 12 (1), 2022-04-11

...The study diagnosed a major depressive disorder (MDD) assessed by well-trained certified psychiatrists through medical examinations....

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Guo Zheng, Zhang Yingli, Chen Shengli, Zhou Zhifeng, Peng Bo, Hou Gangqiang, Qiu Yingwei Frontiers in Neurology 13 2022-04-08

...<jats:sec><jats:title>Objective</jats:title><jats:p>Inter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD)....

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IWASAKI Shinichi, DEGUCHI Yasuhiko, HIROTA Tomoyuki, SHIRAHAMA Yoshiki, NAKAMICHI Yoko, OKAWA Yutaro, UESAKA Yuki, INOUE Koki Ｉｎｄｕｓｔｒｉａｌ　ｈｅａｌｔｈ 61 (1), 68-77, 2022-04-04

<p>Sickness absences are a significant public health and economic problem worldwide. However, sickness absence diagnoses and trends have not been reported in much detail in Japan. This study was a …

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Takuya Saito, Mitsuhiro Ishida, Atsushi Nishiyori, Toshimitsu Ochiai, Hideaki Katagiri, Hideo Matsumoto Journal of Child and Adolescent Psychopharmacology 32 (3), 132-142, 2022-04-01

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鄶, 弘智 前橋工科大学研究紀要 2022-03-31

...In this context, the GIM-based brain patterns were computed to classify the populations between healthy controls and patients with major depressive disorder, which obtained the excepted recognition performance...

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Masaki Kato, Haruhiko Ogata, Hidetoshi Tahara, Akira Shimamoto, Yoshiteru Takekita, Yosuke Koshikawa, Keiichiro Nishida, Shinpei Nonen, Koichiro Higasa, Toshihiko Kinoshita International Journal of Molecular Sciences 23 (7), 3873-, 2022-03-31

...<jats:p>Major depressive disorder (MDD) is a life-impairing disorder, and early successful treatment is important for a favorable prognosis....

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Michaela Krivosova, Eduard Gondas, Radovan Murin, Matus Dohal, Igor Ondrejka, Ingrid Tonhajzerova, Peter Hutka, Nikola Ferencova, Zuzana Visnovcova, Igor Hrtanek, Juraj Mokry Diagnostics 12 (4), 813-, 2022-03-26

...<jats:p>Major depressive disorder (MDD) is a serious mental disease with a pathophysiology that is not yet fully clarified....

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Åsa Hammar, Eivind Haga Ronold, Guro Årdal Rekkedal Frontiers in Psychiatry 13 2022-03-08

...<jats:p>Increasingly, studies have investigated cognitive functioning from the perspective of acute <jats:italic>state</jats:italic>- to remitted phases of Major Depressive Disorder (MDD)....

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永安, 一樹 Journal of Pharmacological Sciences 148 (3), 295-299, 2022-03

Serotonin transporter (SERT) is a membrane transporter which terminates neurotransmission of serotonin through its reuptake. This transporter as well as its substrate have long drawn attention as a …

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Kai Sun, Zhenyu Liu, Guanmao Chen, Zhifeng Zhou, Shuming Zhong, Zhenchao Tang, Shuo Wang, Guifei Zhou, Xuezhi Zhou, Lizhi Shao, Xiaoying Ye, Yingli Zhang, Yanbin Jia, Jiyang Pan, Li Huang, Xia Liu, Jiangang Liu, Jie Tian, Ying Wang Journal of Affective Disorders 300 1-9, 2022-03

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Scott T. Aaronson, Linda L. Carpenter, Todd M. Hutton, Stacia Kraus, Miriam Mina, Kenneth Pages, Luoxi Shi, W. Scott West, Harold A. Sackeim Brain Stimulation 15 (2), 326-336, 2022-03

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Takaki Tanifuji, Shinsuke Aoyama, Yutaka Shinko, Kentaro Mouri, Saehyeon Kim, Seimi Satomi‐Kobayashi, Masakazu Shinohara, Seiji Kawano, Ichiro Sora Psychiatry and Clinical Neurosciences Reports 1 (1), 2022-03

...Those who treated COVID‐19 patients were at greater risk of developing major depressive disorder than those who treated non‐COVID‐19 patients.</jats:p></jats:sec>...

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Kayo Ichihashi, Yoshitaka Kyou, Naomi Hasegawa, Norio Yasui-Furukori, Yoshihito Shimizu, Hikaru Hori, Naoki Hashimoto, Kenta Ide, Yayoi Imamura, Hisashi Yamada, Shinichiro Ochi, Jun-ichi Iga, Yoshikazu Takaesu, Kazutaka Ohi, Takashi Tsuboi, Hitoshi Iida, Hirotaka Yamagata, Akitoyo Hishimoto, Tadasu Horai, Masahide Usami, Manabu Makinodan, Tatsuya Nagasawa, Hiroshi Komatsu, Mikio Kido, Hiroyuki Muraoka, Kiyokazu Atake, Masahiro Takeshima, Chika Kubota, Takahiko Inagaki, Shinichiro Tamai, Taishiro Kishimoto, Ryuji Furihata, Junya Matsumoto, Kenichiro Miura, Ken Inada, Koichiro Watanabe, Kiyoto Kasai, Ryota Hashimoto Asian Journal of Psychiatry 69 103007-, 2022-03

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Micah Cearns, Azmeraw T. Amare, Klaus Oliver Schubert, Anbupalam Thalamuthu, Joseph Frank, Fabian Streit, Mazda Adli, Nirmala Akula, Kazufumi Akiyama, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlund, Abesh Kumar Bhattacharjee, Frank Bellivier, Antonio Benabarre, Susanne Bengesser, Joanna M. Biernacka, Armin Birner, Clara Brichant-Petitjean, Pablo Cervantes, Hsi-Chung Chen, Caterina Chillotti, Sven Cichon, Cristiana Cruceanu, Piotr M. Czerski, Nina Dalkner, Alexandre Dayer, Franziska Degenhardt, Maria Del Zompo, J. Raymond DePaulo, Bruno Étain, Peter Falkai, Andreas J. Forstner, Louise Frisen, Mark A. Frye, Janice M. Fullerton, Sébastien Gard, Julie S. Garnham, Fernando S. Goes, Maria Grigoroiu-Serbanescu, Paul Grof, Ryota Hashimoto, Joanna Hauser, Urs Heilbronner, Stefan Herms, Per Hoffmann, Andrea Hofmann, Liping Hou, Yi-Hsiang Hsu, Stephane Jamain, Esther Jiménez, Jean-Pierre Kahn, Layla Kassem, Po-Hsiu Kuo, Tadafumi Kato, John Kelsoe, Sarah Kittel-Schneider, Sebastian Kliwicki, Barbara König, Ichiro Kusumi, Gonzalo Laje, Mikael Landén, Catharina Lavebratt, Marion Leboyer, Susan G. Leckband, Mario Maj, Mirko Manchia, Lina Martinsson, Michael J. McCarthy, Susan McElroy, Francesc Colom, Marina Mitjans, Francis M. Mondimore, Palmiero Monteleone, Caroline M. Nievergelt, Markus M. Nöthen, Tomas Novák, Claire O'Donovan, Norio Ozaki, Vincent Millischer, Sergi Papiol, Andrea Pfennig, Claudia Pisanu, James B. Potash, Andreas Reif, Eva Reininghaus, Guy A. Rouleau, Janusz K. Rybakowski, Martin Schalling, Peter R. Schofield, Barbara W. Schweizer, Giovanni Severino, Tatyana Shekhtman, Paul D. Shilling, Katzutaka Shimoda, Christian Simhandl, Claire M. Slaney, Alessio Squassina, Thomas Stamm, Pavla Stopkova, Fasil Tekola-Ayele, Alfonso Tortorella, Gustavo Turecki, Julia Veeh, Eduard Vieta, Stephanie H. Witt, Gloria Roberts, Peter P. Zandi, Martin Alda, Michael Bauer, Francis J. McMahon, Philip B. Mitchell, Thomas G. Schulze, Marcella Rietschel, Scott R. Clark, Bernhard T. Baune The British Journal of Psychiatry 220 (4), 219-228, 2022-02-28

...This model stratified patients based on their meta-polygenic loadings for major depressive disorder and schizophrenia and was then trained using clinical data....

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Eun‐Jin Cheon, Carrie E. Bearden, Daqiang Sun, Christopher R. K. Ching, Ole A. Andreassen, Lianne Schmaal, Dick J. Veltman, Sophia I. Thomopoulos, Peter Kochunov, Neda Jahanshad, Paul M. Thompson, Jessica A. Turner, Theo G.M. van Erp Psychiatry and Clinical Neurosciences 76 (5), 140-161, 2022-02-26

...<jats:p>This review compares the main brain abnormalities in schizophrenia (SZ), bipolar disorder (BD), major depressive disorder (MDD), and 22q11.2 Deletion Syndrome (22q11DS) determined by ENIGMA (Enhancing...

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A. J. McGuinness, J. A. Davis, S. L. Dawson, A. Loughman, F. Collier, M. O’Hely, C. A. Simpson, J. Green, W. Marx, C. Hair, G. Guest, M. Mohebbi, M. Berk, D. Stupart, D. Watters, F. N. Jacka Molecular Psychiatry 27 (4), 1920-1935, 2022-02-22

...In this systematic review, we synthesised the current literature investigating differences in gut microbiota composition in people with the major psychiatric disorders, major depressive disorder (MDD),...

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Jessica P. K. Doll, Jorge F. Vázquez-Castellanos, Anna-Chiara Schaub, Nina Schweinfurth, Cedric Kettelhack, Else Schneider, Gulnara Yamanbaeva, Laura Mählmann, Serge Brand, Christoph Beglinger, Stefan Borgwardt, Jeroen Raes, André Schmidt, Undine E. Lang Frontiers in Psychiatry 13 2022-02-17

...Here, we present the first two patients with major depressive disorder ever treated with fecal microbiota transplantation as add-on therapy....

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Mai Sakai, Zhiqian Yu, Ryo Hirayama, Masa Nakasato, Yoshie Kikuchi, Chiaki Ono, Hiroshi Komatsu, Miharu Nakanishi, Hatsumi Yoshii, David Stellwagen, Tomoyuki Furuyashiki, Masaaki Komatsu, Hiroaki Tomita Neural Plasticity 2022 1-13, 2022-02-16

...<jats:p>Major depressive disorder (MDD) is associated with repeated exposure to environmental stress....

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Yuta Inagawa, Katsutoshi Shioda, Rika Kato, Tsuyoshi Okada, Toshiyuki Kobayashi, Shiro Suda International Journal of Psychiatry in Clinical Practice 26 (4), 376-380, 2022-02-13

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Koji Fujimoto, Masako Hosoi, Ryoko Katsuki, Toshio Matsushima, Keitaro Matsuo, Tomohiro Nakao, Nobuyuki Sudo, Takahiro A. Kato Frontiers in Psychiatry 13 2022-02-10

...Analysis was also done of patients with Major Depressive Disorder (MDD).</jats:p></jats:sec><jats:sec><jats:title>Result</jats:title><jats:p>Of the 221 patients, 139 had chronic pain....

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Qun Li, Yuichi Takeuchi, Jiale Wang, Livia Barcsai, Lizeth K Pedraza, Gábor Kozák, Shinya Nakai, Shigeki Kato, Kazuto Kobayashi, Masahiro Ohsawa, Magor L Lőrincz, Orrin Devinsky, Gyorgy Buzsaki, Antal Berényi 2022-02-04

...<jats:title>Abstract</jats:title><jats:p>Although the etiology of major depressive disorder remains poorly understood, impairment of gamma oscillations recently emerged as a potential biomarker for major...

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Meghann C. Ryan, L. Elliot Hong, Kathryn S. Hatch, Si Gao, Shuo Chen, Krystl Haerian, Jingtao Wang, Eric L. Goldwaser, Xiaoming Du, Bhim M. Adhikari, Heather Bruce, Stephanie Hare, Mark D. Kvarta, Neda Jahanshad, Thomas E. Nichols, Paul M. Thompson, Peter Kochunov Human Brain Mapping 43 (6), 1997-2010, 2022-02-03

...<jats:title>Abstract</jats:title><jats:p>Severe mental illnesses (SMI) including major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia spectrum disorder (SSD) elevate accelerated brain...

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Davide Cappon, Tim den Boer, Caleb Jordan, Wanting Yu, Alexander Lo, Nicole LaGanke, Maria Chiara Biagi, Pawel Skorupinski, Giulio Ruffini, Oscar Morales, Eran Metzger, Bradley Manor, Alvaro Pascual-Leone Frontiers in Aging Neuroscience 13 765370-, 2022-02-02

...<jats:p>Major depressive disorder (MDD) is a worldwide cause of disability in older age, especially during the covid pandemic....

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Fuquan Zhang, Shuquan Rao, Hongbao Cao, Xiangrong Zhang, Qiang Wang, Yong Xu, Jing Sun, Chun Wang, Jiu Chen, Xijia Xu, Ning Zhang, Lin Tian, Jianmin Yuan, Guoqiang Wang, Lei Cai, Mingqing Xu, Ancha Baranova Journal of Clinical Investigation 132 (3), 2022-02-01

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Nariko Katayama, Atsuo Nakagawa, Satoshi Umeda, Yuri Terasawa, Takayuki Abe, Chika Kurata, Yohei Sasaki, Dai Mitsuda, Toshiaki Kikuchi, Hajime Tabuchi, Masaru Mimura Journal of Affective Disorders 298 644-655, 2022-02

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Jian Yang, Jingjing Zhou, Jia Zhou, Haixia Wang, Zuoli Sun, Xuequan Zhu, Yi He, Albert H.C. Wong, Fang Liu, Gang Wang Journal of Psychiatric Research 146 172-178, 2022-02

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Penghong Liu, Mingxue Gao, Zhifen Liu, Yanyan Zhang, Hongwei Tu, Lei Lei, Peiyi Wu, Aixia Zhang, Chunxia Yang, Gaizhi Li, Ning Sun, Kerang Zhang Frontiers in Neuroscience 15 2022-01-28

...disorder (MDD)....

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Keiko Yamaguchi, Masaya Ito, Yoshitake Takebayashi, Masaru Horikoshi, Stefan G. Hofmann Clinical Psychology & Psychotherapy 29 (4), 1481-1487, 2022-01-28

...Using an online survey, 1521 participants (406 with major depressive disorder; 479 with one or more anxiety disorders; and 636 with both) answered the Affective Style Questionnaire and measures of emotion...

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Madiha Rasheed, Rabia Asghar, Sundas Firdoos, Nadeem Ahmad, Amina Nazir, Kakar Mohib Ullah, Noumin Li, Fengyuan Zhuang, Zixuan Chen, Yulin Deng International Journal of Molecular Sciences 23 (3), 1294-, 2022-01-24

...<jats:p>Major depressive disorder (MDD) is a neuropsychiatric disorder, which remains challenging to diagnose and manage due to its complex endophenotype....

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Tatyana Strekalova, Yanzhi Liu, Daniel Kiselev, Sharafuddin Khairuddin, Jennifer Lok Yu Chiu, Justin Lam, Ying-Shing Chan, Dmitrii Pavlov, Andrey Proshin, Klaus-Peter Lesch, Daniel C. Anthony, Lee Wei Lim Psychopharmacology 239 (3), 663-693, 2022-01-24

...depression disorder (MDD)....

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Felix Brandl, Benedikt Weise, Satja Mulej Bratec, Nazia Jassim, Daniel Hoffmann Ayala, Teresa Bertram, Markus Ploner, Christian Sorg Neuropsychopharmacology 47 (5), 1071-1080, 2022-01-20

...<jats:title>Abstract</jats:title><jats:p>Major depressive disorder (MDD), anxiety disorders (ANX), and chronic pain (CP) are closely-related disorders with both high degrees of comorbidity among them and...

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Tatsuo Akechi, Izumi Mishiro, Shinji Fujimoto Psycho-Oncology 31 (6), 929-937, 2022-01-20

...<jats:title>Abstract</jats:title><jats:sec><jats:title>Objective</jats:title><jats:p>To estimate the risk of major depressive disorder (MDD) in adolescent and young adult (AYA) patients with cancer in...

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Hitoshi Sakurai, Kengo Yonezawa, Hideaki Tani, Masaru Mimura, Michael Bauer, Hiroyuki Uchida Pharmacopsychiatry 55 (04), 193-202, 2022-01-19

...AXS-05 (a combination of dextromethorphan and bupropion) and ansofaxine hydrochloride showed a positive result over placebo in a phase III study for major depressive...

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Laurence Dion-Albert, Alice Cadoret, Ellen Doney, Fernanda Neutzling Kaufmann, Katarzyna A. Dudek, Beatrice Daigle, Lyonna F. Parise, Flurin Cathomas, Nalia Samba, Natalie Hudson, Manon Lebel, Frederic Aardema, Lahcen Ait Bentaleb, Janique Beauchamp, Hicham Bendahmane, Elise Benoit, Lise Bergeron, Armando Bertone, Natalie Bertrand, Felix-Antoine Berube, Pierre Blanchet, Janick Boissonneault, Christine J. Bolduc, Jean-Pierre Bonin, Francois Borgeat, Richard Boyer, Chantale Breault, Jean-Jacques Breton, Catherine Briand, Jacques Brodeur, Krystele Brule, Lyne Brunet, Sylvie Carriere, Carine Chartrand, Rosemarie Chenard-Soucy, Tommy Chevrette, Emmanuelle Cloutier, Richard Cloutier, Hugues Cormier, Gilles Cote, Joanne Cyr, Pierre David, Luigi De Benedictis, Marie-Claude Delisle, Patricia Deschenes, Cindy D. Desjardins, Gilbert Desmarais, Jean-Luc Dubreucq, Mimi Dumont, Alexandre Dumais, Guylaine Ethier, Carole Feltrin, Amelie Felx, Helen Findlay, Linda Fortier, Denise Fortin, Leo Fortin, Nathe Francois, Valerie Gagne, Marie-Pierre Gagnon, Marie-Claude Gignac-Hens, Charles-Edouard Giguere, Roger Godbout, Christine Grou, Stephane Guay, Francois Guillem, Najia Hachimi-Idrissi, Christophe Herry, Sheilah Hodgins, Saffron Homayoun, Boutheina Jemel, Christian Joyal, Edouard Kouassi, Real Labelle, Denis Lafortune, Michel Lahaie, Souad Lahlafi, Pierre Lalonde, Pierre Landry, Veronique Lapaige, Guylaine Larocque, Caroline Larue, Marc Lavoie, Jean-Jacques Leclerc, Tania Lecomte, Cecile Lecours, Louise Leduc, Marie-France Lelan, Andre Lemieux, Alain Lesage, Andree Letarte, Jean Lepage, Alain Levesque, Olivier Lipp, David Luck, Sonia Lupien, Felix-Antoine Lusignan, Richard Lusignan, Andre J. Luyet, Alykhanhthi Lynhiavu, Jean-Pierre Melun, Celine Morin, Luc Nicole, Francois Noel, Louise Normandeau, Kieron O’Connor, Christine Ouellette, Veronique Parent, Marie-Helene Parizeau, Jean-Francois Pelletier, Julie Pelletier, Marc Pelletier, Pierrich Plusquellec, Diane Poirier, Stephane Potvin, Guylaine Prevost, Marie-Josee Prevost, Pierre Racicot, Marie-France Racine-Gagne, Patrice Renaud, Nicole Ricard, Sylvie Rivet, Michel Rolland, Marc Sasseville, Gabriel Safadi, Sandra Smith, Nicole Smolla, Emmanuel Stip, Jakob Teitelbaum, Alfred Thibault, Lucie Thibault, Stephanye Thibault, Frederic Thomas, Christo Todorov, Valerie Tourjman, Constantin Tranulis, Sonia Trudeau, Gilles Trudel, Nathalie Vacri, Luc Valiquette, Claude Vanier, Kathe Villeneuve, Marie Villeneuve, Philippe Vincent, Marcel Wolfe, Lan Xiong, Angela Zizzi, Matthew Campbell, Gustavo Turecki, Naguib Mechawar, Caroline Menard Nature Communications 13 (1), 164-, 2022-01-10

...<jats:title>Abstract</jats:title><jats:p>Prevalence, symptoms, and treatment of depression suggest that major depressive disorders (MDD) present sex differences....

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Yusuke Matsuzaka, Kayoko Urashima, Shintaro Sakai, Yoshiro Morimoto, Shinji Kanegae, Hirohisa Kinoshita, Akira Imamura, Hiroki Ozawa Neuropsychopharmacology Reports 42 (1), 120-123, 2022-01-05

...depressive disorder, double depression, and chronic major depression....

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Jingyu Lin, Yunai Su, Xiaozhen Lv, Qi Liu, Gang Wang, Jing Wei, Gang Zhu, Qiaoling Chen, Hongjun Tian, Kerang Zhang, Xueyi Wang, Nan Zhang, Hong Yan, Ying Wang, Xin Yu, Tianmei Si European Archives of Psychiatry and Clinical Neuroscience 272 (5), 887-896, 2022-01-05

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Koshiyama, Daisuke, Miura, Kenichiro, 根本, 清貴, Okada, Naohiro, Matsumoto, Junya, Fukunaga, Masaki, Hashimoto, Ryota Human Brain Mapping 43 (1), 182-193, 2022-01

...Moreover, the COCORO study found that schizophrenia, bipolar disorder (n = 211) and autism spectrum disorder (n = 126), but not major depressive disorder (n = 398), share similar white matter microstructural...

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降籏, 隆二, Otsuki, Rei, Hasegawa, Naomi, Tsuboi, Takashi, Numata, Shusuke, Yasui-Furukori, Norio, Kashiwagi, Hiroko, Hori, Hikaru, Ochi, Shinichiro, Muraoka, Hiroyuki, Onitsuka, Toshiaki, Komatsu, Hiroshi, Takeshima, Masahiro, Hishimoto, Akitoyo, Nagasawa, Tatsuya, Takaesu, Yoshikazu, Nakamura, Toshinori, Asami, Takeshi, Miura, Kenichiro, Matsumoto, Junya, Ohi, Kazutaka, Yasuda, Yuka, Iida, Hitoshi, Ogasawara, Kazuyoshi, Hashimoto, Naoki, Ichihashi, Kayo, Yamada, Hisashi, Watanabe, Koichiro, Inada, Ken, Hashimoto, Ryota Sleep Medicine 89 23-30, 2022-01

...Data from 2146 inpatients with schizophrenia and 1031 inpatients with major depressive disorder were analyzed....

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Ryo Mitoma, Shunsuke Tamura, Hiroshi Tateishi, Takako Mitsudo, Ichiro Tanabe, Akira Monji, Yoji Hirano Journal of Affective Disorders Reports 7 100277-, 2022-01

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Nasrin Abdoli, Nader Salari, Niloofar Darvishi, Sima Jafarpour, Mina Solaymani, Masoud Mohammadi, Shamarina Shohaimi Neuroscience & Biobehavioral Reviews 132 1067-1073, 2022-01

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Kasumi Yasuda, Shinichi Yamada, Shinya Uenishi, Natsuko Ikeda, Atsushi Tamaki, Yuji Ohoshi, Tomikimi Tsuji, Shun Takahashi Neuropsychobiology 81 (3), 204-214, 2022

...This study aimed to elucidate the relationship between hippocampal subfield volume and cognitive function in patients with SCZ, bipolar disorder (BP), and major depressive disorder (MDD)....

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Sarah H. Lisanby, Shawn M. McClintock, William V. McCall, Rebecca G. Knapp, C. Munro Cullum, Martina Mueller, Zhi-De Deng, Abeba A. Teklehaimanot, Matthew V. Rudorfer, Elisabeth Bernhardt, George Alexopoulos, Samuel H. Bailine, Mimi C. Briggs, Emma T. Geduldig, Robert M. Greenberg, Mustafa M. Husain, Styliani Kaliora, Vassilios Latoussakis, Lauren S. Liebman, Georgios Petrides, Joan Prudic, Peter B. Rosenquist, Shirlene Sampson, Kristen G. Tobias, Richard D. Weiner, Robert C. Young, Charles H. Kellner The American Journal of Geriatric Psychiatry 30 (1), 15-28, 2022-01

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Xiaoyu Yu, Ying Bai, Bing Han, Minzi Ju, Tianci Tang, Ling Shen, Mingyue Li, Li Yang, Zhao Zhang, Guoku Hu, Jie Chao, Yuan Zhang, Honghong Yao Journal of Extracellular Vesicles 11 (1), 2022-01

...<jats:title>Abstract</jats:title><jats:p>Major depressive disorder (MDD) is the most prevalent psychiatric disorder worldwide and severely limits psychosocial function and quality of life, but no effective...

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Shota Minami, Masaki Kato, Shunichiro Ikeda, Masafumi Yoshimura, Satsuki Ueda, Yosuke Koshikawa, Yoshiteru Takekita, Toshihiko Kinoshita, Keiichiro Nishida Neuropsychobiology 81 (6), 475-483, 2022

<jats:p><b><i>Introduction:</i></b> Functional connectivity is attracting increasing attention for understanding the pathophysiology of depression and predicting the therapeutic efficacy of …

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野田 賀大 日本生物学的精神医学会誌 33 (2), 71-76, 2022

うつ病の病態生理の1つに神経可塑性仮説があるが，rTMS療法はまさに脳内ネットワークの神経可塑性を神経修飾することで治療効果を発揮する物理学的な治療法である。これまでの先行研究からは，rTMSの治療メカニズムには，分子レベルではGABA，NMDA，AMPA，BDNFなどが関与していることが示唆されており，神経画像レベルでは安静時機能的MRI計測によるDLPFCと膝下部前帯状皮質の機能的結合性，デ…

DOI

中谷 善彦, 矢口 真菜美, 荻野 和樹, 野口 理沙子, 山本 直樹, 天野 託 日本薬理学会年会要旨集 96 (0), 3-B-P-201-, 2022

...However, accumulating evidence has indicated that inflammation in the brain may be a key factor in the pathophysiological mechanisms of developing symptoms of major depressive disorder....

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吉田 小莉, 濱田 祐輔, 佐藤 大介, 成田 道子, 山中 章弘, 葛巻 直子, 成田 年 日本薬理学会年会要旨集 95 (0), 1-YIA-34-, 2022

...This maladaptation triggers several kinds of disorders, like major depressive disorder (MDD), psychosomatic disease, and immune dysfunction....

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袴田 優子 日本生物学的精神医学会誌 33 (4), 169-177, 2022

記憶バイアスは，ネガティブな情動刺激に対して生じる情報処理上の偏り「認知バイアス」の一つである。認知バイアスは，ストレスに関連した精神障害の発症と維持・増悪に寄与することから，その病態解明研究において客観的に記述可能な認知行動学的測定単位であるとともに，ストレス関連精神症状に対する有効性が明らかとなっている心理介入法「認知バイアス緩和アプローチ」の重要な治療標的でもある。記憶バイアスとは，ネガテ…

DOI

松崎 広和 日本薬理学会年会要旨集 96 (0), 1-B-W03-1-, 2022

...<p>Major depressive disorder (MDD) is a common and recurrent psychiatric disease, however, the pathogenesis of MDD remains poorly understood....

DOI Web Site

宮田 茂雄 日本薬理学会年会要旨集 96 (0), 3-B-S30-2-, 2022

...<p>Major depressive disorder (MDD) is a highly prevalent psychiatric disorder that is associated with physical impairment, medical comorbidity, and mortality worldwide....

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長谷川 眞也, 毛利 彰宏, 國澤 和生, 窪田 悠力, 倉橋 仁美, 小菅 愛加, 山本 康子, 齋藤 邦明, 鍋島 俊隆 日本薬理学会年会要旨集 95 (0), 1-YIA-12-, 2022

...<p>Chronic stress contributes to the pathogenesis of major depressive disorder (MDD)....

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安藤 千紘, 萩原 雅子, 西谷 直也, 永安 一樹, 白川 久志, 金子 周司 日本薬理学会年会要旨集 95 (0), 2-YIA-52-, 2022

...<p>Major depressive disorder is one of the largest medical and social problems worldwide....

DOI Web Site

Sodeyama Noriko, Tachikawa Hirokazu, Takahashi Sho, Aiba Miyuki, Haraguchi Yayoi, Arai Tetsuaki The Tohoku Journal of Experimental Medicine 257 (3), 261-271, 2022

...“Not receiving compensation for damages” was a risk factor common to major depressive disorder and suicidal ideation....

DOI 機関リポジトリ HANDLE ほか3件 被引用文献1件 参考文献26件

KATO TADAFUMI 順天堂醫事雑誌 68 (1), 17-24, 2022

...Major depressive disorder, on the other hand, is a disorder in which only depressive states occur, and the two are sometimes referred to together as “mood disorders....

DOI Web Site Web Site ほか1件 参考文献27件

毛利 彰宏, 國澤 和生, 齋藤 邦明, 鍋島 俊隆 日本薬理学会年会要旨集 95 (0), 3-S35-2-, 2022

...<p>Tryptophan (TRP) is metabolized via the kynurenine (KYN) pathway, which is related to the pathogenesis of major depressive disorder (MDD)....

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Mizuguchi Daisuke, Omiya Yasuhiro, Takano Takeshi, Nakamura Mitsuteru, Higuchi Masakazu, Shinohara Shuji, So Mirai, Tokuno Shinichi 生体医工学 Annual60 (Abstract), 247_1-247_1, 2022

...We analyzed correlations between the CF and scores of self-administered questionnaires (BDI and PHQ-9), collected twice from the 33 patients with major depressive disorders....

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髙﨑 一朗 日本薬理学会年会要旨集 96 (0), 4-B-S43-3-, 2022

...<p>Major depressive disorder (MDD) is a common psychiatric disorder worldwide; however, the cure rate remains low. Therefore, it is necessary to develop additional safe and effective antidepressants....

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出山 諭司, 南 雅文, 金田 勝幸 日本薬理学会年会要旨集 96 (0), 4-B-S43-1-, 2022

<p>We previously found that intracerebroventricular injections of resolvin E1 (RvE1) and E2 (RvE2) produce antidepressant-like effects in lipopolysaccharide (LPS)-induced depression model mice. …

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Victor M. Tang, Bernard Le Foll, Daniel M. Blumberger, Daphne Voineskos Brain Sciences 12 (1), 48-, 2021-12-30

...<jats:p>Major depressive disorder (MDD) and alcohol use disorder (AUD) are leading causes of disability, and patients are frequently affected by both conditions....

DOI Web Site 被引用文献1件

Javier R. Caso, Karina S. MacDowell, Ana González-Pinto, Saínza García, Javier de Diego-Adeliño, Mar Carceller-Sindreu, Fernando Sarramea, Javier Caballero-Villarraso, Patricia Gracia-García, Concepción De la Cámara, Luis Agüera, María L. Gómez-Lus, Claudio Alba, Juan M. Rodríguez, Juan C. Leza Translational Psychiatry 11 (1), 645-, 2021-12-21

...<jats:title>Abstract</jats:title><jats:p>Although alterations in the gut microbiota have been linked to the pathophysiology of major depressive disorder (MDD), including through effects on the immune response...

DOI PDF Web Site 被引用文献1件

Ryogo Umetsu, Mizuki Tanaka, Yoko Nakayama, Yamato Kato, Natsumi Ueda, Yuri Nishibata, Shiori Hasegawa, Kiyoka Matsumoto, Noriaki Takeyama, Kazuhiro Iguchi, Hiroyuki Tanaka, Eiichi Hinoi, Naoki Inagaki, Masatoshi Inden, Yoshinori Muto, Mitsuhiro Nakamura Frontiers in Pharmacology 12 2021-12-20

...“Mood disorders” and “major depressive disorder” were significant disease terms related to montelukast....

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Annakarina Mundorf, Jutta Peterburs, Sebastian Ocklenburg Frontiers in Systems Neuroscience 15 733898-, 2021-12-14

...With the notable exception of major depressive disorder, all reviewed disorders were associated with distinct patterns of alterations in structural hemispheric asymmetries....

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Sarah R. Moore, Thorhildur Halldorsdottir, Jade Martins, Susanne Lucae, Bertram Müller-Myhsok, Nikola S. Müller, Charlotte Piechaczek, Lisa Feldmann, Franz Joseph Freisleder, Ellen Greimel, Gerd Schulte-Körne, Elisabeth B. Binder, Janine Arloth Translational Psychiatry 11 (1), 632-, 2021-12-13

...Depressive Disorder (MDD) specifically in males and females in the cingulate cortex....

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島田 京司, 庄司 雅紀, 藤原 篤子, 恩田 光子 社会薬学 40 (2), 98-104, 2021-12-10

<p>Depression requires continuous long-term treatment. However, many patients drop out from their treatment program. The purpose of this study is to investigate the current status of pharmacists’ …

DOI 医中誌

Lamiece Hassan, Niels Peek, Karina Lovell, Andre F. Carvalho, Marco Solmi, Brendon Stubbs, Joseph Firth Molecular Psychiatry 27 (2), 1248-1255, 2021-12-07

...<jats:title>Abstract</jats:title><jats:p>People with severe mental illness (SMI; including schizophrenia/psychosis, bipolar disorder (BD), major depressive disorder (MDD)) experience large disparities...

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Viktoriya L. Nikolova, Megan R. B. Smith, Lindsay J. Hall, Anthony J. Cleare, James M. Stone, Allan H. Young JAMA Psychiatry 78 (12), 1343-, 2021-12-01

...Differences in beta diversity were consistently observed only for major depressive disorder and psychosis and schizophrenia....

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Ryoko Hiratsuka, Maho Aoyama, Kento Masukawa, Yoichi Shimizu, Jun Hamano, Yukihiro Sakaguchi, Miwa Watanabe, Tatsuya Morita, Yoshiyuki Kizawa, Satoru Tsuneto, Yasuo Shima, Mitsunori Miyashita Journal of Pain and Symptom Management 62 (6), 1154-1164, 2021-12

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David M. Kern, M. Soledad Cepeda, Frank Wiegand BMC Psychiatry 21 (1), 2021-12

...depressive disorder (MDD) who experience suicidal ideation or a suicide attempt (SI/SA)....

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Neslihan Altunsoy, Didem Sücüllüoğlu Di̇ki̇ci̇, Fikret Poyraz Çökmüş, Hüseyin Murat Özkan, Kadir Aşçibaşi, Deniz Alçi, Erkan Kuru, Serra Yüzeren, Ömer Aydemi̇r Asian Journal of Psychiatry 66 102883-, 2021-12

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Eve Cosker, Marie Moulard, Cédric Baumann, Amandine Luc, Karine Angioi-Duprez, Vincent Laprévote, Raymund Schwan, Thomas Schwitzer Journal of Affective Disorders 295 453-462, 2021-12

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Jian Zhong Yang, Chuan Yuan Kang, Jing Yuan, Yan Zhang, Yu Jun Wei, Li Xu, Fang Zhou, Xinxin Fan Psychoneuroendocrinology 134 105432-, 2021-12

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Jack F. Webster, Salvatore Lecca, Christian Wozny Frontiers in Behavioral Neuroscience 15 2021-11-26

...<jats:p>The lateral habenula (LHb) is a key brain region implicated in the pathology of major depressive disorder (MDD)....

DOI Web Site 被引用文献1件

Shu Liu, Jianbo Xiu, Caiyun Zhu, Kexin Meng, Chen Li, Rongrong Han, Tingfu Du, Lanlan Li, Lingdan Xu, Renjie Liu, Wanwan Zhu, Yan Shen, Qi Xu Nature Communications 12 (1), 6937-, 2021-11-26

...However, it is unclear whether RNA methylation plays a critical role in the pathophysiology of major depression disorder (MDD)....

DOI PDF Web Site 被引用文献1件

Yuri Sakai, Chong Chen, Atsuhito Toyomaki, Naoki Hashimoto, Kan Kitagawa, Takao Inoue, Asumi Sato, Keisuke Makihara, Rie Kameyama, Yumi Wakatsuki, Niki Udo, Ryosuke Shirakawa, Takashi Yokota, Shin Nakagawa, Ichiro Kusumi Frontiers in Behavioral Neuroscience 15 2021-11-22

...We found that in patients diagnosed with major depressive disorder or persistent depressive disorder (<jats:italic>n</jats:italic> = 8), the program resulted in a significant reduction in depressive symptoms...

DOI Web Site 被引用文献1件 参考文献23件

Ikuo Otsuka, Hanga Galfalvy, Jia Guo, Masato Akiyama, Dan Rujescu, Gustavo Turecki, Akitoyo Hishimoto, J. John Mann Psychological Medicine 53 (6), 2689-2697, 2021-11-18

...</jats:p></jats:sec><jats:sec id="S0033291721004700_sec_a3" sec-type="results"><jats:title>Results</jats:title><jats:p>PRSs for major depressive disorder, bipolar disorder, schizophrenia, ADHD, alcohol...

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Ting Sun, Qian Chen, Yan Li BMC Psychiatry 21 (1), 576-, 2021-11-17

...<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Individuals with major depressive disorder (MDD) have high suicidal ideation....

DOI PDF Web Site 被引用文献1件

Jing Wang, Steven W H Chau, Siu Ping Lam, Yaping Liu, Jihui Zhang, Ngan Yin Chan, Maxine M S Cheung, Mandy Wai Man Yu, Jessie C T Tsang, Joey W Y Chan, Bei Huang, Shirley X Li, Vincent Mok, Yun Kwok Wing Journal of Neurology, Neurosurgery & Psychiatry 93 (9), 1010-1017, 2021-11-11

...depressive disorder (MDD)....

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Miguel A. Ortega, Miguel Angel Alvarez-Mon, Cielo García-Montero, Oscar Fraile-Martinez, Guillermo Lahera, Jorge Monserrat, Luis Muñoz-Merida, Fernando Mora, Roberto Rodríguez-Jiménez, Sonia Fernandez-Rojo, Javier Quintero, Melchor Álvarez-Mon Biomedicines 9 (11), 1659-, 2021-11-10

...<jats:p>Major Depressive Disorder (MDD) represents a major global health concern, a body-mind malady of rising prevalence worldwide nowadays....

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Jessica M. Klerk‐Sluis, Marloes J. Huijbers, Stephan Löcke, Jan Spijker, Philip Spinhoven, Anne E. M. Speckens, Henricus G. Ruhe Depression and Anxiety 39 (2), 113-122, 2021-11-09

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Julie Kristine Knudsen, Thomas Yssing Michaelsen, Caspar Bundgaard-Nielsen, René Ernst Nielsen, Simon Hjerrild, Peter Leutscher, Gregers Wegener, Suzette Sørensen Scientific Reports 11 (1), 21869-, 2021-11-08

...<jats:title>Abstract</jats:title><jats:p>Differences in gut microbiota composition have been observed in patients with major depressive disorder (MDD) compared to healthy individuals....

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Yiyun Liu, Haiyang Wang, Siwen Gui, Benhua Zeng, Juncai Pu, Peng Zheng, Li Zeng, Yuanyuan Luo, You Wu, Chanjuan Zhou, Jinlin Song, Ping Ji, Hong Wei, Peng Xie Translational Psychiatry 11 (1), 568-, 2021-11-08

...<jats:title>Abstract</jats:title><jats:p>Major depressive disorder (MDD) is a serious mental illness....

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Norma Angélica Labra Ruiz, Daniel Santamaría Del Ángel, Norma Osnaya Brizuela, Armando Valenzuela Peraza, Hugo Juárez Olguín, Mónica Punzo Soto, David Calderón Guzmán International Journal of Neuropsychopharmacology 25 (1), 46-53, 2021-11-01

...<jats:title>Abstract</jats:title> <jats:p>Major depressive disorder (MDD) is one of the most common psychiatric illnesses in the general population....

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