検索結果 323 件

Komatsubara Tadashi, Tazawa Hiroshi, Hasei Joe, Omori Toshinori, Sugiu Kazuhisa, Mochizuki Yusuke, Demiya Koji, Yoshida Aki, Fujiwara Tomohiro, Kunisada Toshiyuki, Urata Yasuo, Kagawa Shunsuke, Ozaki Toshifumi, Fujiwara Toshiyoshi Acta Medica Okayama 78 (2), 151-161, 2024-04

...We previously demonstrated the therapeutic potential of two telomerase-specific replication-competent oncolytic adenoviruses, OBP-301 and tumor suppressor p53-armed OBP-702, in human STS cells....

DOI 機関リポジトリ

Uotani, Koji, Tazawa, Hiroshi, Hasei, Joe, Fujiwara, Tomohiro, Yoshida, Aki, Yamakawa, Yasuaki, Omori, Toshinori, Sugiu, Kazuhisa, Komatsubara, Tadashi, Kondo, Hiroya, Morita, Takuya, Kiyono, Masahiro, Yokoo, Suguru, Hata, Toshiaki, Kunisada, Toshiyuki, Takeda, Ken, Urata, Yasuo, Fujiwara, Toshiyoshi, Ozaki, Toshifumi PLoS ONE 19 (2), e0298292-, 2024-02-20

...OBP-401-mediated GFP expression was significantly associated with the therapeutic efficacy of OBP-401 in human bone and soft-tissue sarcomas....

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佐々木 剛, 新泉 一美, 春口 麻衣, 清田 直樹, 山田 孝 作業療法 43 (1), 51-60, 2024-02-15

...もOBPの影響を与えていることが明らかとなった．また，OBPの実施意向のある作業療法士は有意にOBPの必要性を認識しており，OBPの知識の深化と信念形成が今後のOBP推進の一助となることが示唆された．...

DOI Web Site

木口 尚人, 齋藤 さわ子 作業療法 43 (1), 42-50, 2024-02-15

<p>作業を用いた実践を促進するより良い講習会のあり方の示唆を得るため，作業を用いた評価技術講習会に参加した作業療法士の作業を用いた実践における困難や不安感（以下，障壁）および作業を用いる実践頻度に対する認識の変化を調査した．受講後，セラピストに起因する作業を用いた評価に加え介入への障壁が低減し，講習会1ヵ月後の時点で作業を用いる実践頻度が増加していた．環境とクライアントに起因する障壁の変化はな…

DOI

Hashimoto, Masashi, Kuroda, Shinji, Kanaya, Nobuhiko, Kadowaki, Daisuke, Yoshida, Yusuke, Sakamoto, Masaki, Hamada, Yuki, Sugimoto, Ryoma, Yagi, Chiaki, Ohtani, Tomoko, Kumon, Kento, Kakiuchi, Yoshihiko, Yasui, Kazuya, Kikuchi, Satoru, Yoshida, Ryuichi, Tazawa, Hiroshi, Kagawa, Shunsuke, Yagi, Takahito, Urata, Yasuo, Fujiwara, Toshiyoshi British Journal of Cancer 130 (7), 1187-1195, 2024-02-05

...and increased TRMs in OBP-702-uninjected tumors....

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小山 進, 山脇 洋輔, 安川 圭司 心身医学 64 (1), 53-59, 2024

<p><b>背景</b>：われわれの先行研究は，腹側被蓋野（VTA）ドパミン神経のレプチン応答の有無や高脂肪食飼育時のドパミンを介した神経興奮性の促進を明らかにした．高脂肪食飼育マウスは易肥満（Ob-P）群と肥満抵抗（Ob-R）群に分かれることが知られている．本研究では，Ob-PマウスではOb-Rマウスに比べて，レプチン/ドパミン作用を介してVTAドパミン神経の興奮性が高まるのではないかという仮…

DOI Web Site 医中誌

黒崎 空, 佐々木 秀一, 田口 晴貴, 柴原 一陽, 隈部 俊宏 神奈川作業療法研究 14 (1), 1-10, 2024

<p>膠芽腫術後患者に対して，重要な作業への復帰を促進するためにAid for Decision-making in Occupation Choice（ADOC）と作業機能障害の種類と評価を用いたOccupation Based Practice（OBP）を行い，退院後の健康関連QOLへの影響を検討した．ADOCでは，ADLよりも仕事や余暇に関する作業が多く抽出された．健康関連QOLや作業機能…

DOI

Tamura, Shuta, Tazawa, Hiroshi, Hori, Naoto, Li, Yuncheng, Yamada, Motohiko, Kikuchi, Satoru, Kuroda, Shinji, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi PLoS ONE 18 (11), e0294491-, 2023-11-16

...Wild-type and KRAS-mutant CRC cells were sensitive to OBP-301 and OBP-702, whereas BRAF-mutant CRC cells were sensitive to OBP-702 but resistant to OBP-301....

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杉原 るる, 松尾 薫, 武田 重昭, 加我 宏之 日本都市計画学会関西支部研究発表会講演概要集 21 (0), 17-20, 2023-07-29

...本研究では、大阪ビジネスパーク（OBP）を対象に､知識創造の視点から屋外空間が持つワークプレイスとしての可能性を探ることを目的とした｡ 調査は、2022年9月にOBPの屋外の着座空間構成について現地調査を実施した。同年11月にワーカーの利用状況についてアンケート調査を実施した。...

DOI Web Site 参考文献2件

Ryohei H. Suzuki, Takumi Hanada, Yoshinobu Hayashi, Shuji Shigenobu, Kiyoto Maekawa, Masaru K. Hojo Insect Molecular Biology 32 (4), 424-435, 2023-04-05

...First, we identified 31 odorant‐binding proteins (OBPs), and three chemosensory protein A (CheA) from the genome data....

DOI 参考文献76件

Araki, Hiroyuki, Tazawa, Hiroshi, Kanaya, Nobuhiko, Kajiwara, Yoshinori, Yamada, Motohiko, Hashimoto, Masashi, Kikuchi, Satoru, Kuroda, Shinji, Yoshida, Ryuichi, Umeda, Yuzo, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi Molecular Therapy - Oncolytics 27 3-13, 2022-12-15

...Further in vivo experiments would be warranted to evaluate the survival benefit of tumor-bearing mice in combination therapy with OBP-702 and PD-1 blockade....

DOI 機関リポジトリ Web Site ほか1件 被引用文献1件 参考文献45件

Kajiwara, Yoshinori, Tazawa, Hiroshi, Yamada, Motohiko, Kanaya, Nobuhiko, Fushimi, Takuro, Kikuchi, Satoru, Kuroda, Shinji, Ohara, Toshiaki, Noma, Kazuhiro, Yoshida, Ryuichi, Umeda, Yuzo, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi Cancer Immunology, Immunotherapy 72 (5), 1285-1300, 2022-11-27

...OBP-702 significantly inhibited GEM-resistant PAN02 tumor growth by suppressing GM-CSF-mediated MDSC accumulation....

DOI 機関リポジトリ PDF ほか1件 参考文献52件

千福 恵子, 佐々木 香純 産業衛生学雑誌 64 (5), 238-243, 2022-09-20

DOI Web Site PubMed 参考文献15件

石光, 俊彦, 本多, 勇晴, 高橋, 知里, 里中, 弘志, 岩嶋, 義雄, 藤乘, 嗣泰, Toshihiko, Ishimitsu, Takeaki, Honda, Chisako, Takahashi, Hiroshi, Satonaka, Yoshio, Iwashima, Akihiro, Tojo Dokkyo Journal of Medical Sciences 49 (1), 9-15, 2022-07-25

高血圧治療ガイドラインでは，診察室血圧（OBP）は1-2分間隔で測定を繰り返し，安定した2回の測定値の平均で評価することとされているが，数多い高血圧患者の実地診療において測定を繰り返すことは難しく，1回の測定で評価される場合も多い．本研究では診察室血圧が高値を呈する高血圧患者において，深呼吸後に測定を繰り返すことによる血圧の変化を検討した． …

機関リポジトリ 医中誌

Yukako Tatsumi, Michihiro Satoh, Kei Asayama, Takahisa Murakami, Takuo Hirose, Azusa Hara, Megumi Tsubota-Utsugi, Ryusuke Inoue, Masahiro Kikuya, Kyoko Nomura, Hirohito Metoki, Atsushi Hozawa, Hideki Katagiri, Yutaka Imai, Takayoshi Ohkubo Journal of Hypertension 40 (7), 1336-1343, 2022-07

...Participants with OBP-defined SDH had a significantly higher estimated mean fasting blood glucose; blood glucose at 30, 60 and 120 min; and HOMA-IR and a lower Matsuda–DeFronzo index than participants...

DOI Web Site 参考文献36件

Wang, Jin, Sakai, Kenji, Kiwa, Toshihiko Molecules 27 (12), 3917-, 2022-06-18

...Computational docking and prediction tools were utilized for OBPs peptide characterization and analysis....

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Jin Wang, Kenji Sakai, Toshihiko Kiwa Molecules 27 (12), 3917-, 2022-06-18

...Computational docking and prediction tools were utilized for OBPs peptide characterization and analysis....

DOI Web Site 参考文献41件

Ogawa, Toshihiro, Kikuchi, Satoru, Tabuchi, Motoyasu, Mitsui, Ema, Une, Yuta, Tazawa, Hiroshi, Kuroda, Shinji, Noma, Kazuhiro, Ohara, Toshiaki, Kagawa, Shunsuke, Urata, Yasuo, Fujiwara, Toshiyoshi Molecular Therapy-Oncolytics 25 249-261, 2022-06-16

...OBP-702 showed cytotoxicity to both GC cells and CAFs but not to NGFs....

機関リポジトリ

Masuda Tomoya, Tazawa Hiroshi, Hashimoto Yuuri, Ieda Takeshi, Kikuchi Satoru, Kuroda Shinji, Noma Kazuhiro, Urata Yasuo, Kagawa Shunsuke, Fujiwara Toshiyoshi Acta Medica Okayama 76 (2), 203-215, 2022-04

...OBP-301 significantly inhibited the EMT phenotype via E1 accumulation. EMT cancer cells were susceptible to OBP-301 via massive autophagy induction....

DOI 機関リポジトリ 医中誌

Cheng Qu, Zhao-kai Yang, Su Wang, Hai-peng Zhao, Feng-qi Li, Xin-ling Yang, Chen Luo Frontiers in Physiology 13 2022-03-08

...Odorant-binding proteins (OBPs) as the first-step of recognizing volatiles, transport odors through sensillum lymph to odorant receptors (ORs)....

DOI Web Site 被引用文献1件

Cristina M. Crava, Yuriy V. Bobkov, Giorgia Sollai, Gianfranco Anfora, Roberto Crnjar, Alberto Maria Cattaneo Frontiers in Ecology and Evolution 9 2022-02-03

...supporting an olfactory function for this appendage, including odorant receptors (ORs), antennal ionotropic receptors (A-IRs), sensory neuron membrane proteins (SNMPs), and odorant-binding proteins (OBPs...

DOI Web Site 被引用文献1件

Daisuke Kaneda, Tomoko Iehara, Ken Kikuchi, Yohei Sugimoto, Norio Nakagawa, Shigeki Yagyu, Mitsuru Miyachi, Eiichi Konishi, Toshiyuki Sakai, Hajime Hosoi Pediatrics International 64 (1), 2022-01

...OBP‐801 inhibited cell proliferation and growth in all the cell lines....

DOI Web Site Web Site ほか1件 参考文献28件

Ikeuchi Katsuma, Nishida Seiji, Orita Yasushi, Sakamoto Chiaki Asian Journal of Occupational Therapy 18 (1), 199-207, 2022

...<p><b>Introduction:</b> Occupation-based practice (OBP) is seldom performed for people with severe acute cerebrovascular accidents (CVA)....

DOI Web Site 医中誌 参考文献9件

千福 恵子, 佐々木 香純 産業衛生学雑誌 63 (6), 304-309, 2021-11-20

DOI Web Site Web Site ほか2件 被引用文献1件 参考文献10件

Tatsuya Kubota, Tatsuhiko Saito, Naotaka Y. Chikasada, Osamu Sandanbata Geophysical Research Letters 48 (21), e2021GL094255-, 2021-11-03

...<jats:title>Abstract</jats:title><jats:p>This study reports an ocean‐bottom pressure gauge (OBP) network, S‐net, which captured meteotsunamis with amplitudes as small as a few cm, and investigates its...

DOI Web Site Web Site ほか1件 被引用文献8件 参考文献50件

後藤 紀史, 寺岡 睦 作業療法 40 (5), 691-698, 2021-10-15

...作業に根ざした実践2.0（Occupation-Based Practice 2.0）は，クライエントの作業機能障害の改善と，クライエントを取り巻く環境で生じる信念対立に対処していく方法である．本報告では，回復期リハビリテーション病棟入院中の脳卒中後遺症を呈したクライエントに対して，OBP 2.0を用いた評価と介入を実施し，回復期リハビリテーション病棟におけるOBP 2.0の臨床有用性を検討した．その...

DOI Web Site 医中誌

Shirakawa, Yasuhiro, Tazawa, Hiroshi, Tanabe, Shunsuke, Kanaya, Nobuhiko, Noma, Kazuhiro, Koujima, Takeshi, Kashima, Hajime, Kato, Takuya, Kuroda, Shinji, Kikuchi, Satoru, Kagawa, Shunsuke, Katsui, Kuniaki, Kanazawa, Susumu, Urata, Yasuo, Fujiwara, Toshiyoshi European Journal of Cancer 153 98-108, 2021-08

...OBP-301 sensitises human cancer cells to ionising radiation by inhibiting DNA repair, and radiation enhances coxsackievirus and adenovirus receptor-mediated OBP-301 infection on the contrary....

機関リポジトリ

Yasuhiro Shirakawa, Hiroshi Tazawa, Shunsuke Tanabe, Nobuhiko Kanaya, Kazuhiro Noma, Takeshi Koujima, Hajime Kashima, Takuya Kato, Shinji Kuroda, Satoru Kikuchi, Shunsuke Kagawa, Kuniaki Katsui, Susumu Kanazawa, Yasuo Urata, Toshiyoshi Fujiwara European Journal of Cancer 153 98-108, 2021-08

DOI Web Site Web Site 被引用文献2件 参考文献33件

Atsushi Ugajin, Katsuhisa Ozaki Frontiers in Insect Science 1 2021-07-30

...), and found that three OBP genes showed enriched expression in the foreleg tarsus....

DOI Web Site 参考文献53件

長谷部 将大, 古桧山 建吾 作業療法 40 (3), 351-358, 2021-06-15

今回，回復期リハビリテーション病棟（以下，回復期病棟）に入院した3事例に対して，「作業機能障害の種類と評価（以下，CAOD）」を用いて，作業機能障害の重症度に着目した価値のある作業に根ざした実践を行った．3事例は異なる経過を辿るも，3事例とも作業機能障害の重症度は改善を示した．そして，その経過を比較検討した結果，作業機能障害の重症度は事例の作業環境や作業の特性によって変動しやすく，対象者に作業を…

DOI Web Site 医中誌

Sugiu, Kazuhisa, Tazawa, Hiroshi, Hasei, Joe, Yamakawa, Yasuaki, Omori, Toshinori, Komatsubara, Tadashi, Mochizuki, Yusuke, Kondo, Hiroya, Osaki, Shuhei, Fujiwara, Tomohiro, Yoshida, Aki, Kunisada, Toshiyuki, Ueda, Koji, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi Cancer Chemotherapy and Pharmacology 88 (3), 513-524, 2021-06-10

...Here, we demonstrate the chemosensitizing effect of OBP-702 in human OS cells....

DOI 機関リポジトリ PDF ほか1件 被引用文献1件 参考文献42件

Kakiuchi, Yoshihiko, Kuroda, Shinji, Kanaya, Nobuhiko, Kumon, Kento, Tsumura, Tomoko, Hashimoto, Masashi, Yagi, Chiaki, Sugimoto, Ryoma, Hamada, Yuki, Kikuchi, Satoru, Nishizaki, Masahiko, Kagawa, Shunsuke, Tazawa, Hiroshi, Urata, Yasuo, Fujiwara, Toshiyoshi Molecular Therapy 29 (10), 2920-2930, 2021-05-21

...EVs isolated from the supernatant of HCT116 human colon carcinoma cells treated with OBP-301 were confirmed to contain OBP-301, and they showed cytotoxic activity (apoptosis and autophagy) similar to OBP...

DOI 機関リポジトリ Web Site ほか1件 被引用文献1件 参考文献40件

Osamu Sandanbata, Shingo Watada, Tung-Cheng Ho, Kenji Satake Geophysical Journal International 226 (3), 1975-1985, 2021-05-17

..., indicating the effects due to the four factors are detectable by high-sampling OBP gauges that are deployed over broad oceanic regions....

DOI PDF PDF 被引用文献3件 参考文献29件

梶　正史, 大神　浩一郎 ネットワークポリマー論文集 42 (3), 84-89, 2021-05-10

...ジフェニレンエーテル構造を有する4,4’- オキシビス（グリシジルオキシベンゼン）（OBGB）と4,4’- オキシビスフェノール（OBP）を反応させた場合，結晶性の硬化物を与えることが分かっている。硬化剤としてOBP に対して4,4’- ジアミノジフェニルスルホン（ DDS）を併用した場合，DDS の割合が30 wt％まで結晶性の硬化物を与えることを確認した。...

DOI Web Site

Omori, Toshinori, Tazawa, Hiroshi, Yamakawa, Yasuaki, Osaki, Shuhei, Hasei, Joe, Sugiu, Kazuhisa, Komatsubara, Tadashi, Fujiwara, Tomohiro, Yoshida, Aki, Kunisada, Toshiyuki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi PLoS ONE 16 (4), e0250643-, 2021-04-22

...In this study, we investigated the radiosensitizing effect of OBP-301 in human STS cells....

DOI 機関リポジトリ Web Site 被引用文献1件 参考文献44件

大野 勘太, 川俣 祐李菜, 友利 幸之介, 澤田 辰徳 作業療法 40 (2), 178-185, 2021-04-15

上肢整形外科疾患患者に対する作業を基盤とした実践（Occupation-based practice）の有効性を検証することを目的に，システマティックレビューとメタアナリシスを実施した．PubMed，Web of Scienceを使用し全335編を精読し，4編が適合論文となった．機能障害を測定する効果指標においては，対照群との有意な改善は認められなかった．一方で，Disability of …

DOI Web Site 医中誌

Rie Sano, Yoichiro Takahashi, Haruki Fukuda, Megumi Harada, Akira Hayakawa, Takafumi Okawa, Rieko Kubo, Haruo Takeshita, Junichi Tsukada, Yoshihiko Kominato Scientific Reports 11 (1), 7325-, 2021-04-01

...These findings suggest that<jats:italic>OBP2B</jats:italic>could be co-regulated by the + 22.6-kb site of<jats:italic>ABO</jats:italic>.</jats:p>...

DOI PDF Web Site 被引用文献2件 参考文献39件

Tatsuya Kubota, Tatsuhiko Saito, Hiroaki Tsushima, Ryota Hino, Yusaku Ohta, Syuichi Suzuki, Daisuke Inazu Geophysical Research Letters 48 (7), e2020GL091664-, 2021-03-30

...We applied this method to the OBP data of the 2011 Tohoku‐Oki earthquake....

DOI Web Site Web Site ほか1件 被引用文献5件 参考文献70件

Karen Rihani, Jean-François Ferveur, Loïc Briand Biomolecules 11 (4), 509-, 2021-03-30

...Odorant-binding proteins (OBPs) form a family of proteins involved in chemoreception....

DOI Web Site 被引用文献2件

沈 吉穎, 許 俊卿, 今村 都 Co*Design 9 57-77, 2021-01-31

...しかし、近年、梅田をはじめとする近隣の新興ビジネスエリアとの競争において劣勢に立たされ、OBP地区のエリアマネジメントを担う大阪ビジネスパーク協議会（以下OBP協議会とする）では同地区の相対的な魅力の低下が問題視され、再活性化が喫緊の課題になっている。しかしながら、こうしたエリアの再活性化という課題はOBP地区に特有のものではない。...

DOI HANDLE Web Site

Yano, Shuya, Tazawa, Hiroshi, Kishimoto, Hiroyuki, Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Hoffman, Robert M. International Journal of Molecular Sciences 22 (2), 879-, 2021-01-17

...We generated three types of telomerase-specific replication-competent oncolytic adenovirus: OBP-301; a green fluorescent protein (GFP)-expressing adenovirus, OBP-401; and Killer-Red-armed OBP-301....

機関リポジトリ

Shuya Yano, Hiroshi Tazawa, Hiroyuki Kishimoto, Shunsuke Kagawa, Toshiyoshi Fujiwara, Robert M. Hoffman International Journal of Molecular Sciences 22 (2), 879-, 2021-01-17

...We generated three types of telomerase-specific replication-competent oncolytic adenovirus: OBP-301; a green fluorescent protein (GFP)-expressing adenovirus, OBP-401; and Killer-Red-armed OBP-301....

DOI Web Site 参考文献120件

Yoichiro Dobashi, Daisuke Inazu Frontiers in Earth Science 8 2021-01-12

...OBP data....

DOI Web Site 被引用文献1件 参考文献91件

Yuji Yamamoto, Atsushi Mukai, Toru Ikushima, Yasuo Urata, Shigeru Kinoshita, Junji Hamuro, Morio Ueno, Chie Sotozono Scientific Reports 10 (1), 2020-12-01

...The purpose of this study was to investigate the ability of a pluripotent epigenetic regulator OBP-801 (OBP) to ameliorate extracellular matrix formation in a rabbit model of GFS....

DOI PDF Web Site 参考文献52件

Sina Cassau, Jürgen Krieger Cell and Tissue Research 383 (1), 21-33, 2020-11-27

...Besides odorant-binding proteins (OBPs) and olfactory receptors, so-called sensory neuron membrane proteins (SNMPs) are indicated to play a critical role in the detection of certain odorants....

DOI PDF Web Site 被引用文献4件

梶　正史, 大神　浩一郎 ネットワークポリマー論文集 41 (6), 252-259, 2020-11-10

...さらに，4,4’- オキシビスフェノール（OBP）との反応物は257.4 ℃と高い融点を持つ結晶性の硬化物を与えるとともに，熱伝導率は0.32 W/m・K であり，非結晶性のDGBPA 硬化物に対して約1.5 倍の値を示した。</p>...

DOI Web Site

Mochizuki, Yusuke, Tazawa, Hiroshi, Demiya, Koji, Kure, Miho, Kondo, Hiroya, Komatsubara, Tadashi, Sugiu, Kazuhisa, Hasei, Joe, Yoshida, Aki, Kunisada, Toshiyuki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi Cancer Immunology, Immunotherapy 70 1405-1417, 2020-11-05

...The cytopathic activity of OBP-502 in both cells was analyzed using the XTT assay....

機関リポジトリ

Runxian Yao, Mingming Zhao, Ling Zhong, Yi Li, Dazhi Li, Ziniu Deng, Xianfeng Ma Pest Management Science 77 (3), 1214-1225, 2020-10-21

...The aim of this study was to characterize the functional OBPs of <jats:italic>B. minax</jats:italic> and identify specific volatile organic compounds in the <jats:italic>Citrus</jats:italic> genus as OBP...

DOI Web Site Web Site 被引用文献1件

Marc Delcroix, Salma Sylla, Ricardo Hueso, François Colas, David Baratoux EPSC 14 775-, 2020-10-08

...a68I6Vp2pjxj8B79r/xd4E8LLD/AMKR8bWiw/8ACZeNdB8KPfMw+P1wZv7Pi1mS8W1Ai+0vAkJuIFZnrr/+GiP2uv8Aof8A4Df+GG8bf/RDUhn6x0V+Tn/DRH7XX/Q//Ab/AMMN42/+iGo/4aI/a6/6H/4Df+GG8bf/AEQ1AH6x0V+Th/aH/a6/6H/4Df8Ahh/G/wDT9obP86...

DOI 被引用文献1件

Itziar Garate-Lopez, Ricardo Hueso, Yeon Joo Lee, Valeria Mangano, Kandis Lea Jessup, Javier Peralta, Agustin Sanchez-Lavega, Joe Zender, Johannes Benkhoff, Go Murakami, Manuel Scherf 2020-10-08

...4xZ2Xnzp2Lixcv4u233wYhBDNnzmS0FsOGDYNQKPzXtxUOh4Pt27dj/PjxCAsL+1cKxIyMDFy6dAmBgYG081MoVKD/x9QeLDWM8xzX4T3F1cXYobkDo/qOgpaGVqvfu3TpgokTJ7a6Xlpaiq+++gpjxoyBvb09LCwsUF1dzayUlKvxttDS+v/3qKurtxm72dbWVkVl2l56SsEqkUggFosRGxvL/Obp6YlOnTqhrq5OxYe2k5NT...

DOI 被引用文献1件

Ryota Nakano, Masatoshi Hirabayashi 2020-10-08

...JY4iD0cPvW4qXIyY8FNff+3s0IZLL5PtQ8IGrgVs+9q4aVK9TD2IHMSLi0BQk/rsgA3VUQ799ABv+/BwecMdiQ+4C9C3MgYNcs4PgiqGJJ61Tr28gPZ7q21y1siyRei0iCs35C/C/efPwaFcTVv76WXzygYdxxXuvQPhnPwcsXnSqiU+p+JMW3CUfv+KKK6iIrzQNLjm77NVfoDz6gg21NcAv78OBP69HvScM61NK8MKSGxFGwUgY4TqW8kU7DMsi9cCMBQKuQWMBL5eqwxy47JDJBXF5TD7b4oj43frdHkS2...

DOI 被引用文献1件

Yohei Sugimoto, Yoshiki Katsumi, Tomoko Iehara, Daisuke Kaneda, Chihiro Tomoyasu, Kazutaka Ouchi, Hideki Yoshida, Mitsuru Miyachi, Shigeki Yagyu, Ken Kikuchi, Kunihiko Tsuchiya, Yasumichi Kuwahara, Toshiyuki Sakai, Hajime Hosoi Molecular Cancer Therapeutics 19 (10), 1992-2000, 2020-10-01

...However, Western blotting and cell-cycle analysis revealed that OBP-801 did not activate the P21-RB pathway in some cell lines. p21 knockout indicated that p21 did not dominate the OBP-801 antitumor effect...

DOI PDF 被引用文献1件 参考文献41件

Tanimoto, Terutaka, Tazawa, Hiroshi, Ieda, Takeshi, Nouso, Hiroshi, Tani, Morimichi, Oyama, Takanori, Urata, Yasuo, Kagawa, Shunsuke, Noda, Takuo, Fujiwara, Toshiyoshi Molecular Therapy - Oncolytics 18 14-23, 2020-09-25

...OBP-301 and OBP-702 significantly suppressed the growth of subcutaneous CHP-134 tumors....

機関リポジトリ

Ishikawa, Wataru, Kikuchi, Satoru, Ogawa, Toshihiro, Tabuchi, Motoyasu, Tazawa, Hiroshi, Kuroda, Shinji, Noma, Kazuhiro, Nishizaki, Masahiko, Kagawa, Shunsuke, Urata, Yasuo, Fujiwara, Toshiyoshi Molecular Therapy - Oncolytics 18 262-271, 2020-09-25

...OBP-401 synergistically suppressed the viability of human gastric cancer cells in combination with PTX. PTX enhanced the antitumor effect of OBP-401 due to enhanced viral replication in cancer cells....

機関リポジトリ

Andrea Belgrano, Sebastián Villasante Population Ecology 63 (1), 102-107, 2020-09-24

...To create bridges between them, we develop an Ocean's Benefits to People (OBP) framework that embraces the blue economy, equity, the UN SDGs goals and support an Ecosystem‐Based Management (EBM) for the...

DOI Web Site Web Site 被引用文献1件

Mizutani, Ayumu, Yomogida, Kiyoshi, Tanioka, Yuichiro Journal of Geophysical Research, Oceans 125 (9), e2020-, 2020-09

...Based on this comparison, we adopted a band-pass filter of 0.05–0.15 Hz to remove ocean-bottom acceleration components from the OBP data....

HANDLE

Mao-Ye Li, Xiu-Yun Jiang, Yu-Zhe Qi, Yuan-Jie Huang, Shi-Guang Li, Su Liu Journal of Insect Science 20 (5), 1-, 2020-09-01

...These OBPs displayed high amino acid identity with their respective orthologs in other lepidopterans, and several conserved motifs were identified within these OBPs....

DOI PDF 被引用文献1件

Ayumu Mizutani, Kiyoshi Yomogida, Yuichiro Tanioka Journal of Geophysical Research: Oceans 125 (9), 2020-08-25

...Based on this comparison, we adopted a band‐pass filter of 0.05–0.15 Hz to remove ocean‐bottom acceleration components from the OBP data....

DOI Web Site Web Site ほか2件 被引用文献6件

Koujima, Takeshi, Tazawa, Hiroshi, Ieda, Takeshi, Araki, Hiroyuki, Fushimi, Takuro, Shoji, Ryohei, Kuroda, Shinji, Kikuchi, Satoru, Yoshida, Ryuichi, Umeda, Yuzo, Teraishi, Fuminori, Urata, Yasuo, Mizuguchi, Hiroyuki, Fujiwara, Toshiyoshi Molecular Therapy - Oncolytics 17 107-117, 2020-06-26

...OBP-702 infection suppressed ERK signaling and inhibited PDAC cell migration and invasion more efficiently than OBP-301....

DOI 機関リポジトリ Web Site ほか1件 被引用文献6件 参考文献54件

Khasim Cali, Krishna C. Persaud Scientific Reports 10 (1), 2020-03-03

...<jats:title>Abstract</jats:title><jats:p>The binding pockets of odorant binding proteins from <jats:italic>Anopheles gambiae (OBP1</jats:italic> and <jats:italic>OBP47)</jats:italic> were analysed using...

DOI PDF Web Site 被引用文献1件

Alexey Androsov, Olaf Boebel, Jens Schröter, Sergey Danilov, Andreas Macrander, Ioana Ivanciu Journal of Geophysical Research: Oceans 125 (3), e2019JC015469-, 2020-03

...Furthermore, despite good agreement in the amplitude of variability, the in situ and simulated OBP show only modest correlation.</jats:p>...

DOI Web Site Web Site ほか2件 被引用文献1件

Tazawa, Hiroshi, Hasei, Joe, Yano, Shuya, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi Cancers 12 (2), 2020-02-18

...), and tumor suppressor p53-armed OBP-702....

機関リポジトリ

Hiroshi Tazawa, Joe Hasei, Shuya Yano, Shunsuke Kagawa, Toshifumi Ozaki, Toshiyoshi Fujiwara Cancers 12 (2), 478-, 2020-02-18

...), and tumor suppressor p53-armed OBP-702....

DOI Web Site 被引用文献1件

Yusuke Chihara, Yosuke Iizumi, Mano Horinaka, Motoki Watanabe, Wakana Goi, Mie Morita, Emi Nishimoto, Yoshihiro Sowa, Tadaaki Yamada, Koichi Takayama, Toshiyuki Sakai International Journal of Oncology 2020-01-24

DOI 参考文献42件

Kanaya, Nobuhiko, Kuroda, Shinji, Kakiuchi, Yoshihiko, Kumon, Kento, Tsumura, Tomoko, Hashimoto, Masashi, Morihiro, Toshiaki, Kubota, Tetsushi, Aoyama, Katsuyuki, Kikuchi, Satoru, Nishizaki, Masahiko, Kagawa, Shunsuke, Tazawa, Hiroshi, Mizuguchi, Hiroyuki, Urata, Yasuo, Fujiwara, Toshiyoshi Molecular Therapy 28 (3), 794-804, 2020-01-10

...Here, we examined the potential of OBP-502, an OBP-301 variant, as an agent for inducing immunogenic cell death (ICD) and synergistically enhancing the efficacy of OBP-502 with PD-1 Ab using CT26 murine...

機関リポジトリ

Yusuke Shiota, Takeshi Sakurai Odorant Binding and Chemosensory Proteins 325-344, 2020

DOI Web Site Web Site 参考文献38件

尾﨑 まみこ 日本毒性学会学術年会 47.1 (0), S11-3-, 2020

...昆虫の苦味受容については2000年ごろまではほとんどわかっておらず、私達とイタリアの研究グループがほぼ同時にハエの味覚器で苦味受容細胞を機能的に特定することに成功したが、その細胞が、経口毒の検出に関わって緊急な嘔吐反応を引き起こすきっかけとなっていることは、味覚器における匂い物質結合蛋白質(gustatory OBP)の関与に気づいた私達の研究によって初めて明らかとなった。...

DOI

Karen Rihani, Stéphane Fraichard, Isabelle Chauvel, Nicolas Poirier, Thomas Delompré, Fabrice Neiers, Teiichi Tanimura, Jean-François Ferveur, Loïc Briand Communications Biology 2 (1), 425-, 2019-11-22

...We mapped the cells expressing OBP19b and compared the electrophysiological responses of a single taste sensillum to several amino acids: OBP19b mutant flies showed a reduced response compared to control...

DOI PDF Web Site 被引用文献1件 参考文献57件

Elizabeth A Scheuermann, Dean P Smith Genetics 213 (3), 897-909, 2019-11-01

...(OBP83a)....

DOI PDF 被引用文献1件

Peipei Xu, Weiming Cai PLOS Genetics 15 (10), e1008465-, 2019-10-18

DOI Web Site 被引用文献2件

Frederick Yoo, Zachary M. Soler, Jennifer K. Mulligan, Kristina A. Storck, Jensine M. Lamira, Whitney N. Pasquini, Jonathan B. Hill, Tegan E. Noonan, Brandon J. Washington, Rodney J. Schlosser International Forum of Allergy & Rhinology 9 (10), 1151-1158, 2019-08-23

...In localization studies, OBP concentrations were significantly higher in OC than IT mucus (<jats:italic>p</jats:italic> = 0.006)....

DOI Web Site Web Site 被引用文献3件

Fujiwara, Toshiyoshi Annals of gastroenterological surgery 3 (4), 396-404, 2019-07-05

...We constructed an attenuated adenovirus 5 vector (telomelysin, OBP-301) in which the hTERT promoter element drives expression of E1 genes....

機関リポジトリ 医中誌

Toshiyoshi Fujiwara Annals of Gastroenterological Surgery 3 (4), 396-404, 2019-07

...We constructed an attenuated adenovirus 5 vector (telomelysin, <jats:styled-content style="fixed-case">OBP</jats:styled-content>‐301) in which the <jats:styled-content style="fixed-case">hTERT</jats:styled-content...

DOI Web Site Web Site ほか1件 被引用文献5件

髙野 大貴, 寺岡 睦 作業療法 38 (3), 358-364, 2019-06-15

...作業に根ざした実践（Occupation-Based Practice 2.0：OBP 2.0）は，クライエントの作業機能障害を評価しつつ，それを取り巻く信念対立に対処していく方法論である．本報告では，地域在住で脳卒中後遺症を有するクライエントに対してOBP 2.0を用いた評価と介入を実施し，訪問作業療法（訪問OT）におけるOBP 2.0の臨床有用性を検討した．その結果，作業機能障害の改善と生活機能...

DOI Web Site 医中誌

Uqba Khan, Talia Biran, Allyson J. Ocean, Elizabeta C. Popa, Joseph T. Ruggiero, Doru Paul, Chelsea Garcia, David Carr-Locke, Reem Sharaiha, Yasuo Urata, Manish A. Shah Journal of Clinical Oncology 37 (15_suppl), TPS4145-TPS4145, 2019-05-20

...Results of a phase I study of OBP-301 in solid tumor pts demonstrated the safety and efficacy of intra-tumoral injection of OBP-301....

DOI Web Site 被引用文献1件

Yuji Itoh, Takuya Nishimura, Keisuke Ariyoshi, Hiroyuki Matsumoto Journal of Geophysical Research: Solid Earth 124 (4), 4205-4230, 2019-04

...Uplift at the OBP sites does not constrain the absolute slip magnitude between the updip and downdip sides of the OBP sites but requires the slip in the updip side to be smaller than that in the downdip...

DOI Web Site Web Site ほか1件 被引用文献10件 参考文献87件

T. Beuvier, I. Probert, L. Beaufort, B. Suchéras-Marx, Y. Chushkin, F. Zontone, A. Gibaud Nature Communications 10 (1), 2019-02-14

...The curvation of coccoliths allows inference of a positive correlation between cell nucleus, OBPS and coccolith sizes.</jats:p>...

DOI PDF Web Site 被引用文献1件

Chihiro Tomoyasu, Ken Kikuchi, Daisuke Kaneda, Shigeki Yagyu, Mitsuru Miyachi, Kunihiko Tsuchiya, Tomoko Iehara, Toshiyuki Sakai, Hajime Hosoi Oncology Reports 2019-02-01

DOI

M. Falchetto, G. Ciossani, F. Scolari, A. Di Cosimo, S. Nenci, L. M. Field, A. Mattevi, J.‐J. Zhou, G. Gasperi, F. Forneris Insect Molecular Biology 28 (3), 431-443, 2019-01-17

...The monomeric structure shows the typical OBP folding, constituted by six α‐helical elements interconnected by three disulphide bridges....

DOI Web Site Web Site 被引用文献1件

Tomoya Muramoto, Yoshihiro Ito, Daisuke Inazu, Laura M. Wallace, Ryota Hino, Syuichi Suzuki, Spahr C. Webb, Stuart Henrys Geophysical Research Letters 46 (1), 303-310, 2019-01-13

...We undertake barotropic modeling to remove oceanographic signals from data from an OBP array deployed offshore New Zealand in 2014/2015....

DOI Web Site Web Site ほか3件 被引用文献5件 参考文献18件

Neha Soleja, Ovais Manzoor, Preeti Nandal, Mohd. Mohsin Organic & Biomolecular Chemistry 17 (9), 2413-2422, 2019

...<p>Upon binding of alcohols, Obp_IIa undergoes conformational changes resulting in transfer of energy in the form of FRET from donor to the acceptor fluorophore.</p>...

DOI Web Site 被引用文献2件

Anastasios Kollias, Emelina Stambolliu, Konstantinos G. Kyriakoulis, Areti Gravvani, George S. Stergiou The Journal of Clinical Hypertension 21 (2), 148-155, 2018-12-25

...However, there was a trend toward higher attended than unattended OBP at higher OBP levels....

DOI Web Site Web Site 被引用文献1件

Jennifer S. Sun, Shuke Xiao, John R. Carlson Open Biology 8 (12), 180208-, 2018-12

...Here we describe the identification of the first Obps and some cardinal properties of these proteins....

DOI Web Site Web Site 被引用文献1件

Jun-Feng Cheng, Ting Yu, Zhong-Jian Chen, Yu-Peng Chen, Lei Gao, Wen-Hu Zhang, Bo Jiang, Xue Bai, Jun Liu, Yong-Yue Lu 2018-10-25

...We found that 1) at the adult developmental stage, there were 14 highly expressed OBPs (FPKM>100) in <jats:italic>B. dorsalis</jats:italic> and 7 highly expressed OBPs in <jats:italic>B. minax</jats:italic...

DOI PDF Web Site ほか1件 被引用文献1件

Chihiro Tomoyasu, Ken Kikuchi, Daisuke Kaneda, Shigeki Yagyu, Mitsuru Miyachi, Kunihiko Tsuchiya, Tomoko Iehara, Toshiyuki Sakai, Hajime Hosoi Oncology Reports 2018-10-22

DOI

Tatsuya Kubota, Tatsuhiko Saito, Yoshihiro Ito, Yoshihiro Kaneko, Laura M. Wallace, Syuichi Suzuki, Ryota Hino, Stuart Henrys Journal of Geophysical Research: Solid Earth 123 (10), 8767-8779, 2018-10

...When this event occurred, ocean bottom pressure gauges (OBPs), installed ~170 km south of the source area, clearly recorded direct tsunami from the source to OBPs (~ −1.5 cm), and tsunami from coastal...

DOI Web Site Web Site ほか3件 被引用文献12件 参考文献36件

Asada Akikazu, Hayakawa Hideki, Yanase Natsuki, Abe Kanae, Sakurai Fuminori, Mizuguchi Hiroyuki, Urata Yasuo Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 41 (10), 1615-1619, 2018-10-01

...We measured the GFP₅₀ titers for three types of recombinant adenoviruses (OBP-401, OBP-1101, and OBP-1106)....

DOI Web Site Web Site ほか2件 参考文献26件

Paolo Pelosi, Jiao Zhu, Wolfgang Knoll Sensors 18 (10), 3248-, 2018-09-27

...In particular, soluble olfaction proteins, including odorant-binding proteins (OBPs) of vertebrates and insects, chemosensory proteins (CSPs) and Niemann-Pick type C2 (NPC2) proteins possess interesting...

DOI Web Site 被引用文献1件

Megumi Watanabe, Shunsuke Kagawa, Kazuya Kuwada, Yuuri Hashimoto, Kunitoshi Shigeyasu, Michihiro Ishida, Shuichi Sakamoto, Atene Ito, Satoru Kikuchi, Shinji Kuroda, Hiroyuki Kishimoto, Shuta Tomida, Ryuichi Yoshida, Hiroshi Tazawa, Yasuo Urata, Toshiyoshi Fujiwara Cancer Science 109 (10), 3263-3271, 2018-09-23

...styled-content style="fixed-case">GFP</jats:styled-content>)‐expressing attenuated adenovirus in which the telomerase promoter regulates viral replication (TelomeScan, <jats:styled-content style="fixed-case">OBP...

DOI Web Site Web Site ほか2件 被引用文献4件 参考文献32件

Jennifer S Sun, Nikki K Larter, J Sebastian Chahda, Douglas Rioux, Ankita Gumaste, John R Carlson eLife 7 e39249-, 2018-09-19

...Remarkably, loss of Obp59a and humidity response leads to an increase in desiccation resistance....

DOI PDF Web Site ほか1件 被引用文献1件

Hisako Ono, Yoshihiro Sowa, Mano Horinaka, Yosuke Iizumi, Motoki Watanabe, Mie Morita, Emi Nishimoto, Tetsuya Taguchi, Toshiyuki Sakai Breast Cancer Research and Treatment 171 (1), 43-52, 2018-05-11

DOI PDF Web Site 被引用文献4件 参考文献35件

Alison McAfee, Abigail Chapman, Immacolata Iovinella, Ylonna Gallagher-Kurtzke, Troy F. Collins, Heather Higo, Lufiani L. Madilao, Paolo Pelosi, Leonard J. Foster Scientific Reports 8 (1), 5719-, 2018-04-09

...and OBP18)....

DOI PDF Web Site 被引用文献3件

Eguchi Kazuo, Miyashita Hiroshi, Shimada Kazuyuki, ABC-J II investigators Vascular Failure 2 (2), 66-73, 2018-03-31

...3: normal OBP and high CBP; and Group 4 as both normal....

DOI Web Site 参考文献29件

Immacolata Iovinella, Alison McAfee, Guido Mastrobuoni, Stefan Kempa, Leonard J. Foster, Paolo Pelosi, Francesca Romana Dani 2018-02-07

...Sequence analysis shows that four proteins can be assigned to the odorant-binding protein (OBP)-like class, which bear some similarity to insect OBPs, but so far are only reported in some Chelicerata....

DOI Web Site 被引用文献1件

HAN Wei, WANG Baosheng, FENG Zhenqian, ZHAO Baokang, YU Wanrong, TANG Zhu IEICE Transactions on Communications E101.B (3), 825-834, 2018

...., the limited on-board processing (OBP), insufficient link resources and long propagation delay....

DOI Web Site 参考文献12件

Toshiya Takamura, Mano Horinaka, Shusuke Yasuda, Seijiro Toriyama, Yuichi Aono, Yoshihiro Sowa, Tsuneharu Miki, Osamu Ukimura, Toshiyuki Sakai Oncology Reports 2017-12-01

DOI

Huan Liu, Xiao-Feng Zhao, Lang Fu, Yi-Ye Han, Jin Chen, Yong-Yue Lu Scientific Reports 7 (1), 2017-11-21

...These results indicate that <jats:italic>Bdor</jats:italic>OBP2 may play an essential role in the molecular mechanism underlying <jats:italic>B. dorsalis</jats:italic> olfactory perception of ME....

DOI PDF Web Site 被引用文献1件

Nurit Eliash, Nitin K. Singh, Starlin Thangarajan, Noa Sela, Dena Leshkowitz, Yosi Kamer, Ilia Zaidman, Ada Rafaeli, Victoria Soroker Scientific Reports 7 (1), 2017-10-12

...These include Niemann-Pick disease protein, type C2 (NPC2), gustatory receptors (GRs), ionotropic receptors (IRs), sensory neuron membrane proteins (SNMPs) and odorant binding proteins (OBP)....

DOI PDF Web Site 被引用文献1件

Iyan E. Mulia, Daisuke Inazu, Takuji Waseda, Aditya Riadi Gusman Journal of Geophysical Research: Oceans 122 (10), 7924-7937, 2017-10

...Since most of the OBP gauges are located inside the source region, the recorded tsunami signals exhibit significant offsets from surface measurements due to coseismic seafloor deformation effects....

DOI Web Site Web Site 被引用文献14件 参考文献41件

Makoto Akiyama, Yoshihiro Sowa, Tomoyuki Taniguchi, Motoki Watanabe, Shingo Yogosawa, Jo Kitawaki, Toshiyuki Sakai Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 25 (8), 1245-1252, 2017-09-21

...We investigated the efficacy and molecular mechanisms of three combined treatments (TCTs)—a novel histone deacetylase (HDAC) inhibitor OBP-801/YM753, 5-fluorouracil (5-FU), and paclitaxel (PTX)—in human...

DOI Web Site 被引用文献1件 参考文献31件

Martina Černá, Barbora Kuntová, Pavel Talacko, Romana Stopková, Pavel Stopka Scientific Reports 7 (1), 11674-, 2017-09-15

...Thus, we suggest that MUPs and potentially also OBPs are important components of female vaginal advertising of the house mouse.</jats:p>...

DOI PDF Web Site 被引用文献1件

Chia‐Wei Hsu, Isabella Velicogna Geophysical Research Letters 44 (17), 8953-8961, 2017-09-09

...We evaluate the GRACE‐derived SLF using ocean bottom pressure (OBP) data from stations in the tropics, where OBP errors are the lowest....

DOI Web Site Web Site 被引用文献2件

Yasuaki Yamakawa, Hiroshi Tazawa, Joe Hasei, Shuhei Osaki, Toshinori Omori, Kazuhisa Sugiu, Tadashi Komatsubara, Kouji Uotani, Tomohiro Fujiwara, Aki Yoshida, Toshiyuki Kunisada, Yasuo Urata, Shunsuke Kagawa, Toshifumi Ozaki, Toshiyoshi Fujiwara Cancer Science 108 (9), 1870-1880, 2017-08-03

...Although tumor‐specific replicating oncolytic adenovirus <jats:styled-content style="fixed-case">OBP</jats:styled-content>‐301 induces an antitumor effect in an osteosarcoma tumor, it cannot prevent bone...

DOI Web Site Web Site ほか2件 被引用文献2件 参考文献47件

Paolo Pelosi, Immacolata Iovinella, Jiao Zhu, Guirong Wang, Francesca R. Dani Biological Reviews 93 (1), 184-200, 2017-05-07

...<jats:title>ABSTRACT</jats:title><jats:p>Odorant‐binding proteins (<jats:styled-content style="fixed-case">OBPs</jats:styled-content>) and chemosensory proteins (<jats:styled-content style="fixed-case"...

DOI Web Site Web Site 被引用文献2件

小池 日登美 糖尿病診療マスター 15 (5), 370-374, 2017-05

DOI

Toshinori Sato, Seiya Hasegawa, Akihiro Kono, Hajime Shiobara, Takeo Yagi, Tomoaki Yamada, Masanao Shinohara, Norihisa Usui Geophysical Research Letters 44 (6), 2710-2715, 2017-03-25

...Most large SSEs occur under the ocean, and continuous OBP measurements have been used previously for their detection....

DOI Web Site Web Site 被引用文献10件 参考文献19件

Bart Rymen, Ayako Kawamura, Sabine Schäfer, Christian Breuer, Akira Iwase, Michitaro Shibata, Miho Ikeda, Nobutaka Mitsuda, Csaba Koncz, Masaru Ohme-Takagi, Minami Matsui, Keiko Sugimoto Plant Physiology 173 (3), 1750-1762, 2017-02-06

DOI Web Site 被引用文献7件

S Yano, K Takehara, H Kishimoto, H Tazawa, Y Urata, S Kagawa, M Bouvet, T Fujiwara, R M Hoffman Cancer Gene Therapy 24 (2), 45-47, 2017-01-20

DOI PDF Web Site 被引用文献4件

Hirakawa Haruo, Nishi Yasuyuki 耳鼻咽喉科臨床　補冊 148 (0), 10-11, 2017

...OBPE without any other significant findings on routine examination was diagnosed in 24 patients....

DOI Web Site 参考文献2件

Hirakawa Haruo, Sugimoto Ichiro 耳鼻咽喉科臨床　補冊 151 (0), 10-11, 2017

...Tofisopam, which is effective for normalizing sympathetic hypersensitivity, was administered to 13 dizzy patients with OBPE with no other abnormal findings....

DOI Web Site 参考文献1件

LIU Yanqing, DONG Liang IEICE Transactions on Communications E100.B (8), 1489-1497, 2017

...Several OFDM subcarriers are selected to accommodate the adjusting weights for OBP and PAPR reduction....

DOI Web Site 参考文献24件

平川 治男, 杉本 一郎 耳鼻咽喉科臨床 110 (5), 359-363, 2017

...Tofisopam, which is effective for normalizing sympathetic hypersensitivity, was administered to 13 dizzy patients with OBPE with no other abnormal findings....

DOI Web Site Web Site ほか1件 参考文献1件

Teppei Onishi, Hiroshi Tazawa, Yuuri Hashimoto, Makoto Takeuchi, Takeshi Otani, Shuji Nakamura, Fuminori Sakurai, Hiroyuki Mizuguchi, Hiroyuki Kishimoto, Yuzo Umeda, Yasuhiro Shirakawa, Yasuo Urata, Shunsuke Kagawa, Toshiyoshi Fujiwara Scientific Reports 6 (1), 2016-11-30

...Moreover, intraperitoneal administration of HOZOT cells loaded with OBP-401/F35 significantly suppressed peritoneally disseminated tumor growth in mice....

DOI PDF Web Site 被引用文献1件 参考文献35件

Elena Ramirez‐Parra, Juan Perianez‐Rodriguez, Sara Navarro‐Neila, Inmaculada Gude, Miguel A. Moreno‐Risueno, Juan C. del Pozo New Phytologist 213 (4), 1787-1801, 2016-11-17

...<jats:styled-content style="fixed-case">OBP</jats:styled-content>4 controls cell elongation and differentiation in root cells....

DOI Web Site Web Site ほか2件 被引用文献2件

Nikki K Larter, Jennifer S Sun, John R Carlson eLife 5 e20242-, 2016-11-15

...The results lay a foundation for an incisive analysis of Obp function. The map identifies a sensillum type that contains a single abundant Obp, Obp28a....

DOI PDF Web Site ほか1件 被引用文献3件

Shuya Yano, Kiyoto Takehara, Hiroyuki Kishimoto, Hiroshi Tazawa, Yasuo Urata, Shunsuke Kagawa, Michael Bouvet, Toshiyoshi Fujiwara, Robert M. Hoffman Oncotarget 7 (51), 85273-85282, 2016-11-11

DOI Web Site 被引用文献2件

Wei Zhang, Arun Wanchoo, Almudena Ortiz-Urquiza, Yuxian Xia, Nemat O. Keyhani Scientific Reports 6 (1), 2016-10-21

...> (<jats:italic>OBP3</jats:italic>) gene....

DOI PDF Web Site 被引用文献1件

Cecilia Peralta‐Ferriz, James H. Morison, John M. Wallace Geophysical Research Letters 43 (17), 9183-9191, 2016-09-14

...After cross validation, two predictors—North Pole OBP record and wind‐OBP coupling from maximum covariance analysis—explain 50% of the total variance of the Arctic OBP....

DOI Web Site Web Site ほか3件 被引用文献1件

Seijiro Toriyama, Mano Horinaka, Shusuke Yasuda, Tomoyuki Taniguchi, Yuichi Aono, Toshiya Takamura, Yukako Morioka, Tsuneharu Miki, Osamu Ukimura, Toshiyuki Sakai Molecular Cancer Therapeutics 15 (9), 2066-2075, 2016-09-01

...Therefore, we conjectured that the apoptosis induced by OBP-801 and celecoxib is at least partially dependent on DR5....

DOI PDF 被引用文献2件 参考文献32件

田中 啓規, 寺岡 睦, 佐伯 昌彦 作業療法 35 (4), 436-444, 2016-08-15

DOI Web Site 医中誌

Shinya Sato, Keisuke Katsushima, Keiko Shinjo, Akira Hatanaka, Fumiharu Ohka, Shugo Suzuki, Aya Naiki-Ito, Norihito Soga, Satoru Takahashi, Yutaka Kondo Cancer Research 76 (14), 4192-4204, 2016-07-14

...Here, we examined the molecular effects of a HDAC inhibitor, OBP-801, on AR expression and tumor cell growth in prostate cancers....

DOI PDF 被引用文献2件 参考文献50件

Shuhei Osaki, Hiroshi Tazawa, Joe Hasei, Yasuaki Yamakawa, Toshinori Omori, Kazuhisa Sugiu, Tadashi Komatsubara, Tomohiro Fujiwara, Tsuyoshi Sasaki, Toshiyuki Kunisada, Aki Yoshida, Yasuo Urata, Shunsuke Kagawa, Toshifumi Ozaki, Toshiyoshi Fujiwara Scientific Reports 6 (1), 28953-, 2016-06-30

...The molecular mechanism underlying the chemosensitizing effect of OBP-301 was evaluated in aspects of apoptosis induction....

DOI PDF Web Site 被引用文献8件 参考文献49件

Peipei Xu, Haiying Chen, Lu Ying, Weiming Cai Scientific Reports 6 (1), 27705-, 2016-06-14

...Here, we report that the DOF transcription factor <jats:italic>OBP4</jats:italic> negatively regulates cell proliferation and expansion. OBP4 is a nuclear protein....

DOI PDF Web Site 被引用文献2件

Akiyama,Makoto, Mori,Taisuke, Ito,Fumitake, Matsushima,Hiroshi, Kitawaki,Jo 日本産科婦人科學會雜誌 68 (2), 522-, 2016-02-01

NDLデジタルコレクション 医中誌

Lai Xu, Joseph Ziegelbauer, Rong Wang, Wells W. Wu, Rong-Fong Shen, Hartmut Juhl, Yaqin Zhang, Amy Rosenberg Clinical Cancer Research 22 (3), 773-784, 2016-01-31

<jats:title>Abstract</jats:title> <jats:p>Purpose: To gain insight into factors involved in tumor progression and metastasis, we examined the role of noncoding RNAs in the biologic …

DOI PDF 被引用文献1件

Liu Rui, Zhu Tizheng, Li Jian, Wu Tao, Li Qian, Meng Yaqian, Cao Qiang, Zhang Min Food Science and Technology Research 22 (1), 101-109, 2016

...The solubility of OBP increased from 8.1 to 11.3 mg/mL. The average molecular weights of raw OBP (rOBP) and superfine ground OBP (sOBP) were 655.6 and 489.6 kDa, respectively....

DOI Web Site 参考文献31件

河平 一宏, 木原 綾子, 谷口 彰冶 皮膚の科学 15 (5), 332-336, 2016

第1例：40歳代，女性。10歳頃よりアトピー性皮膚炎と診断され，治療を受け寛解・増悪を繰り返していた。41歳時に，四肢と背部に小丘疹が出現し，増悪したため当院を受診した。第2例：30歳代，女性。幼少期よりアトピー性皮膚炎と診断され治療を受けてきた。両下腿に丘疹が出現し増加した。症状が増悪したため当院を受診した。2例とも病理検査にてアミロイド苔癬と診断し，ステロイド内服・外用，抗ヒスタミン剤を内服…

DOI 医中誌

平川 治男, 西 康行 耳鼻咽喉科臨床 109 (9), 611-616, 2016

...OBPE without any other significant findings on routine examination was diagnosed in 24 patients....

DOI Web Site Web Site ほか1件 被引用文献2件 参考文献4件

Robert A. Smith, Dana N. Raugi, Vincent H. Wu, Sally S. Leong, Kate M. Parker, Mariah K. Oakes, Papa Salif Sow, Selly Ba, Moussa Seydi, Geoffrey S. Gottlieb Antimicrobial Agents and Chemotherapy 59 (12), 7437-7446, 2015-12

..., we evaluated the<jats:italic>in vitro</jats:italic>activity of the investigational nucleoside analog BMS-986001 (2′,3′-didehydro-3′-deoxy-4′-ethynylthymidine; also known as censavudine, festinavir, OBP...

DOI Web Site 被引用文献1件

Jun Niu, Yinlei Chen, Jiyong An, Xinyu Hou, Jian Cai, Jia Wang, Zhixiang Zhang, Shanzhi Lin Scientific Reports 5 (1), 2015-10-08

...material for industrial and medicinal application in China, but the complex regulatory mechanisms of carbon source partitioning into terpenoid biosynthetic pathway (TBP) and oil biosynthetic pathway (OBP...

DOI PDF Web Site 被引用文献1件

Christine Missbach, Heiko Vogel, Bill S. Hansson, Ewald Groβe-Wilde Chemical Senses 40 (9), 615-626, 2015-09-16

DOI PDF 被引用文献1件

Melanie Larisika, Caroline Kotlowski, Christoph Steininger, Rosa Mastrogiacomo, Paolo Pelosi, Stefan Schütz, Serban F. Peteu, Christoph Kleber, Ciril Reiner‐Rozman, Christoph Nowak, Wolfgang Knoll Angewandte Chemie International Edition 54 (45), 13245-13248, 2015-09-14

...<jats:title>Abstract</jats:title><jats:p>An olfactory biosensor based on a reduced graphene oxide (rGO) field‐effect transistor (FET), functionalized by the odorant‐binding protein 14 (OBP14) from the...

DOI Web Site Web Site ほか1件 被引用文献2件

河平 一宏, 木原 綾子, 谷口 彰治 臨床皮膚科 69 (8), 548-553, 2015-07-01

DOI Web Site 医中誌

Michael M. Watkins, David N. Wiese, Dah‐Ning Yuan, Carmen Boening, Felix W. Landerer Journal of Geophysical Research: Solid Earth 120 (4), 2648-2671, 2015-04

...Ocean bottom pressure (OBP) time series derived from the mascon solutions are shown to have greater correlation with in situ data than do spherical harmonic solutions (increase in correlation coefficient...

DOI Web Site Web Site 被引用文献13件

R. Dwi Susanto, Y. Tony Song Journal of Geophysical Research: Oceans 120 (4), 2844-2855, 2015-04

...Here we have demonstrated a plausible approach to derive the ITF transport proxy using satellite altimetry sea surface height (SSH), gravimetry ocean bottom pressure (OBP) data, in situ measurements from...

DOI Web Site Web Site ほか3件 被引用文献5件

Akiyama,Makoto, Mori,Taisuke, Sawada,Morio, Kuroboshi,Haruo, Tatsumi,Hiroshi, Yamamoto,Takuro, Ito,Fumitake, Matsushima,Hiroshi, Iwasaku,Kazuhiro, Kitawaki,Jo 日本産科婦人科學會雜誌 67 (2), 1014-, 2015-02-01

NDLデジタルコレクション 医中誌

Mohammad Yusuf Mulla, Elena Tuccori, Maria Magliulo, Gianluca Lattanzi, Gerardo Palazzo, Krishna Persaud, Luisa Torsi Nature Communications 6 (1), 6010-, 2015-01-16

...<jats:title>Abstract</jats:title><jats:p>Peripheral events in olfaction involve odorant binding proteins (OBPs) whose role in the recognition of different volatile chemicals is yet unclear....

DOI PDF Web Site 被引用文献5件

Javier Varas, Katja Graumann, Kim Osman, Mónica Pradillo, David E. Evans, Juan L. Santos, Susan J. Armstrong The Plant Journal 81 (2), 329-346, 2015-01

<jats:title>Summary</jats:title><jats:p>The movement of chromosomes during meiosis involves location of their telomeres at the inner surface of the nuclear envelope. Sad1/<jats:styled-content …

DOI Web Site Web Site 被引用文献4件

滝口 和樹, 木田 仁, 田川 義之, 亀田 正治 流体工学部門講演会講演論文集 2015 (0), _1112-1_-_1112-2_, 2015

...We developed a collecting device like olfactory mechanism of animals: thin film of water including odorant binding proteins (OBPs), which play a major role in transport of hydrophobic odor molecules to...

DOI Web Site

河平 一宏, 木原 綾子, 蔭山 充, 谷口 彰治 皮膚の科学 14 (4), 175-178, 2015

症例は70歳代，女性。以前より他院呼吸器内科で咳と慢性副鼻腔炎のため増悪時のみ治療をされていた。2012年6月頃より全指趾爪の肥厚，成長遅延，一部の黄色変化をきたし，上記病院皮膚科で黄色爪症候群と診断されたが治療されなかったため同月当院を受診した。当科でも黄色爪症候群と診断し，クラリスロマイシン内服，ステロイド外用による治療を行ったが効果なかった。しかし，副鼻腔炎に対して処方された辛夷清肺湯内服…

DOI 医中誌

KIDA Hitoshi, TSUKADA Satoshi, TAGAWA Yoshiyuki, SATO Ryoichi, KAMEDA Masaharu Mechanical Engineering Journal 2 (4), 15-00244-15-00244, 2015

...Two kinds of OBPs derived from <i>Bombyx mori</i> (Pheromone Binding Protein 1: PBP1, General Odorant Binding Protein 2: GOBP2) were used as additive in pure water....

DOI Web Site 参考文献20件

折舘 伸彦, 高橋 秀聡, 百束 紘, 佐野 大佑 耳鼻と臨床 60 (Suppl.1), S70-S74, 2014-11-20

...その結果、放射線耐性細胞株に対する OBP-301 感染と放射線治療の併用は <i>in vitro</i> および <i>in vivo</i> で単独治療と比較して有意に高い抗腫瘍効果を発揮し、相乗効果が認められた。 OBP-301 感染は用量依存性に DNA 修復能に関連する複合体の発現増加を抑制した。...

DOI 医中誌

Hae Woo Lee, Andrew Christie, Jason A. Starkey, Erik K. Read, Seongkyu Yoon Journal of Chemical Technology & Biotechnology 90 (2), 291-302, 2014-09-29

<jats:title>Abstract</jats:title><jats:sec><jats:title>BACKGROUND</jats:title><jats:p>In the production of therapeutic proteins using Chinese hamster ovary (<jats:styled-content …

DOI Web Site Web Site 被引用文献2件

C. Petrick, H. Dobslaw, I. Bergmann‐Wolf, N. Schön, K. Matthes, M. Thomas Journal of Geophysical Research: Oceans 119 (8), 5190-5202, 2014-08

...<jats:title>Abstract</jats:title><jats:p>One decade of time‐variable gravity field observations from the GRACE satellite mission reveals low‐frequency ocean bottom pressure (OBP) variability of up to 2.5...

DOI Web Site Web Site 被引用文献1件

寺岡 睦, 京極 真 作業療法 33 (3), 249-258, 2014-06-15

DOI Web Site 医中誌 被引用文献1件

Xiao Zhou, Katja Graumann, Lennart Wirthmueller, Jonathan D.G. Jones, Iris Meier Journal of Cell Biology 205 (5), 677-692, 2014-06-02

<jats:p>Although a plethora of nuclear envelope (NE) transmembrane proteins (NETs) have been identified in opisthokonts, plant NETs are largely unknown. The only known NET homologues in plants are …

DOI PDF 被引用文献6件

Akinobu Furutani, Yoshihiro Sowa, Hitoshi Fujiwara, Eigo Otsuji, Toshiyuki Sakai Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 21 (5), 281-286, 2014-05-30

...Western blot analysis showed that OBP-801/YM753 suppressed the expression of thymidylate synthase induced by 5-FU....

DOI Web Site 被引用文献1件 参考文献22件

Shigeyasu, Kunitoshi, Tazawa, Hiroshi, Hashimoto, Yuuri, Mori, Yoshiko, Nishizaki, Masahiko, Kishimoto, Hiroyuki, Nagasaka, Takeshi, Kuroda, Shinji, Urata, Yasuo, Goel, Ajay, Kagawa, Shunsuke, Fujiwara, Toshiyoshi Gut 2014-05-28

...capture live CTCs among millions of peripheral blood leukocytes using a green fluorescent protein (GFP)-expressing attenuated adenovirus, in which the telomerase promoter regulates viral replication (OBP...

機関リポジトリ

福山, 博文 地域政策科学研究 11 27-40, 2014-03

The purpose of this paper is to estimate both a performance model and a salary model of professional sports players by using a performance data in Major League Baseball (MLB), a performance data in …

機関リポジトリ Web Site

Cecilia Peralta-Ferriz, James H. Morison, John M. Wallace, Jennifer A. Bonin, Jinlun Zhang Journal of Climate 27 (4), 1445-1468, 2014-02-10

...The forcing and dynamics associated with the observed OBP changes are explored....

DOI PDF 被引用文献4件

Akiyama,Makoto, Mori,Taisuke, Sawada,Morio, Kuroboshi,Haruo, Tatsumi,Hiroshi, Yamamoto,Takuro, Matsushima,Hiroshi, Iwasaku,Kazuhiro, Kitawaki,Jo 日本産科婦人科學會雜誌 66 (2), 936-, 2014-02-01

NDLデジタルコレクション 医中誌

和田 萌実, 泉 典洋, 渡部 靖憲 土木学会論文集Ｂ１（水工学） 70 (4), I_1177-I_1182, 2014

...It has been observed that an ocean bottom presimeter (OBP) and an ocean bottom seismometer (OBS) were sagged to the deep ocean by approximately 1 km, which suggests the possibility of the generation of...

DOI Web Site 参考文献6件

Kandasamy Karthikeyan, Paramasivan Manivannan, Durairaj Rajesh Zoological science 31 (1), 31-36, 2014-01

DOI Web Site Web Site ほか1件 参考文献39件

Yano, Shuya, Tazawa, Hiroshi, Hashimoto, Yuuri, Shirakawa, Yasuhiro, Kuroda, Shinji, Nishizaki, Masahiko, Kishimoto, Hiroyuki, Uno, Futoshi, Nagasaka, Takeshi, Urata, Yasuo, Kagawa, Shunsuke, Hoffman, Robert M., Fujiwara, Toshiyoshi Clinical Cancer Research 19 (23), 6495-6505, 2013-12-01

...We investigated the efficacy of OBP-301 against quiescent cancer stem-like cells....

機関リポジトリ

Shuya Yano, Hiroshi Tazawa, Yuuri Hashimoto, Yasuhiro Shirakawa, Shinji Kuroda, Masahiko Nishizaki, Hiroyuki Kishimoto, Futoshi Uno, Takeshi Nagasaka, Yasuo Urata, Shunsuke Kagawa, Robert M. Hoffman, Toshiyoshi Fujiwara Clinical Cancer Research 19 (23), 6495-6505, 2013-12-01

...We investigated the efficacy of OBP-301 against quiescent cancer stem–like cells....

DOI PDF 被引用文献15件 参考文献39件

Tazawa Hiroshi, Kagawa Shunsuke, Fujiwara Toshiyoshi Acta Medica Okayama 67 (6), 333-342, 2013-12

...OBP-301-mediated cytopathic activity is significantly associated with induction of autophagy biomarkers....

DOI 機関リポジトリ PubMed ほか1件 被引用文献1件

Samuel S. C. Rund, Nicolle A. Bonar, Matthew M. Champion, John P. Ghazi, Cameron M. Houk, Matthew T. Leming, Zainulabeuddin Syed, Giles E. Duffield Scientific Reports 3 (1), 2494-, 2013-08-29

...The pre-dusk/dusk peaks in OBPs and takeout gene expression correspond with peak protein abundance at night and in turn coincide with the time of increased olfactory sensitivity to odorants requiring OBPs...

DOI PDF Web Site 被引用文献1件

Jean‐Marie Heydel, Alexandra Coelho, Nicolas Thiebaud, Arièle Legendre, Anne‐Marie Le Bon, Philippe Faure, Fabrice Neiers, Yves Artur, Jérôme Golebiowski, Loïc Briand The Anatomical Record 296 (9), 1333-1345, 2013-07-31

...Odorant‐binding proteins (OBPs), the first group of proteins have been investigated for many years....

DOI Web Site Web Site 被引用文献2件

TAKESHI YAMADA, MANO HORINAKA, MASAHIDE SHINNOH, TAKASHI YOSHIOKA, TSUNEHARU MIKI, TOSHIYUKI SAKAI International Journal of Oncology 43 (4), 1080-1086, 2013-07-30

DOI Web Site 被引用文献3件

Hideaki Takahashi, Hiroshi Hyakusoku, Chihiro Horii, Masahiro Takahashi, Goshi Nishimura, Takahide Taguchi, Norio Kondo, Atsuko Sakakibara, Yasuo Urata, Daisuke Sano Head & Neck 36 (3), 411-418, 2013-06

...This study evaluated the efficacy of combination treatment with OBP‐301, a telomerase‐specific replication‐selective adenovirus, and radiotherapy in overcoming radioresistance by examining its effect on...

DOI Web Site Web Site 被引用文献1件 参考文献38件

Takashi Yoshioka, Shingo Yogosawa, Takeshi Yamada, Jo Kitawaki, Toshiyuki Sakai Gynecologic Oncology 129 (2), 425-432, 2013-05

DOI Web Site Web Site 被引用文献8件 参考文献41件

Samuel SC Rund, James E Gentile, Giles E Duffield BMC Genomics 14 (1), 218-, 2013-04-03

...We reveal that OBPs have unique expression patterns as mosquitoes make the transition from LD to DD conditions....

DOI PDF 被引用文献1件

Hasei, Joe, Sasaki, Tsuyoshi, Tazawa, Hiroshi, Osaki, Shuhei, Yamakawa, Yasuaki, Kunisada, Toshiyuki, Yoshida, Aki, Hashimoto, Yuuri, Onishi, Teppei, Uno, Futoshi, Kagawa, Shunsuke, Urata, Yasuo, Ozaki, Toshifumi, Fujiwara, Toshiyoshi Molecular Cancer Therapeutics 12 (3), 314-325, 2013-03

...The cytopathic activity of OBP-702 was examined in OBP-301-sensitive (U2OS and HOS) and OBP-301-resistant (SaOS-2 and MNNG/HOS) human osteosarcoma cells....

DOI 機関リポジトリ PDF 被引用文献19件 参考文献50件

Walter S. Leal Annual Review of Entomology 58 (1), 373-391, 2013-01-07

...OBPs contribute to the sensitivity of the olfactory system by transporting odorants through the sensillar lymph, but there are competing hypotheses on how they act at the end of the journey....

DOI Web Site 被引用文献9件

新井 和乃, 成瀬 元, 川村 喜一郎, 入野 智久, 池原 研, 齋藤 有, 村山 雅史, 三浦 亮, 日野 亮太, 伊藤 喜宏, 稲津 大祐, 横川 美和, 泉 典洋 日本地質学会学術大会講演要旨 2013 (0), 042-, 2013

DOI

Stephen F. Garczynski, Brad S. Coates, Thomas R. Unruh, Scott Schaeffer, Derick Jiwan, Tyson Koepke, Amit Dhingra Insect Science 20 (5), 559-574, 2012-12-06

...Putative chemosensory proteins (12) and odorant binding proteins (OBPs) (18) were annotated, which included three putative general OBP (GOBP), one more than typically reported for other Lepidoptera....

DOI Web Site Web Site 被引用文献1件

Hanayama Yoshihisa, Uchida Haruhito Adam, Nakamura Yoshio, Makino Hirofumi Acta Medica Okayama 66 (6), 449-459, 2012-12

...Patients were considered to have morning hypertension when their self-measured systolic MHBPs were 135mmHg or higher, irrespective of their diastolic MHBP and office blood pressures (OBPs)....

DOI 機関リポジトリ PubMed ほか1件

Hashimoto, Yuuri, Tazawa, Hiroshi, Teraishi, Fuminori, Kojima, Toru, Watanabe, Yuichi, Uno, Futoshi, Yano, Shuya, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi PLoS ONE 7 (6), 2012-06-15

...OBP-301-mediated E1A was expressed within hypoxic areas of human xenograft tumors in mice....

機関リポジトリ

Takashi Matsuo Applied entomology and zoology 47 (2), 137-142, 2012-05

DOI PDF Web Site ほか2件 被引用文献3件 参考文献18件

Armin Köhl, Frank Siegismund, Detlef Stammer Journal of Geophysical Research: Oceans 117 (C4), C04032-, 2012-04

...OBP data owing to the fact that only the former two need to include the unresolved eddy signal....

DOI Web Site Web Site 被引用文献3件

Kuroda Shinji, Urata Yasuo, Fujiwara Toshiyoshi Acta Medica Okayama 66 (2), 83-92, 2012-04

...Additionally, we showed that a telomerase-dependent oncolytic adenovirus that we developed (OBP-301 [telomelysin]) produces profound radiosensitizing effects by inhibiting the MRN complex via the adenoviral...

DOI 機関リポジトリ PubMed ほか1件

A. Andalib, S. Akhtari, R. Rigal, G. Curnew, J.‐M. Leclerc, M. Vaillancourt, J.‐C. Tardif Internal Medicine Journal 42 (3), 260-266, 2012-03

...MH was defined in nondiabetic patients as an OBP <140/90 mmHg and an HBPM ≥135/85 mmHg, and in those with diabetes as an OBP <130/80 mmHg and an HBPM ≥125/75 mmHg....

DOI Web Site Web Site 被引用文献2件

Anneleen Cornelissen, Stephen C. Hardies, Olga V. Shaburova, Victor N. Krylov, Wesley Mattheus, Andrew M. Kropinski, Rob Lavigne Journal of Virology 86 (3), 1844-1852, 2012-02

...<jats:p> The 283,757-bp double-stranded DNA genome of <jats:named-content content-type="genus-species">Pseudomonas fluorescens</jats:named-content> phage OBP...

DOI Web Site 被引用文献2件

Xiao Zhou, Katja Graumann, David E. Evans, Iris Meier Journal of Cell Biology 196 (2), 203-211, 2012-01-23

<jats:p>Inner nuclear membrane Sad1/UNC-84 (SUN) proteins interact with outer nuclear membrane (ONM) Klarsicht/ANC-1/Syne homology (KASH) proteins, forming linkers of nucleoskeleton to cytoskeleton …

DOI PDF 被引用文献12件

ハラダ, エリコ, ナカガワ, ジュン, アサノ, ツナキ, タオカ, マサト, ソリマチ, ヒロユキ, イトウ, ヨシヒロ, アイガキ, トシロウ, マツオ, タカシ, Harada, Eriko, Nakagawa, Jun, Asano, Tsunaki, Taoka, Masato, Sorimachi, Hiroyuki, Ito, Yoshihiro, Aigaki, Toshiro, Matsuo, Takashi PLoS ONE 7 (1), e29710-1-e29710-11, 2012-01

...Two OBP genes, Obp57d and Obp57e, were involved in the evolution of host-plant preference in Drosophila sechellia....

DOI 機関リポジトリ HANDLE ほか1件 被引用文献4件 参考文献36件

Silvia Spinelli, Amandine Lagarde, Immacolata Iovinella, Pierre Legrand, Mariella Tegoni, Paolo Pelosi, Christian Cambillau Insect Biochemistry and Molecular Biology 42 (1), 41-50, 2012-01

DOI Web Site Web Site 被引用文献1件

香川 俊輔, 矢野 修也, 藤原 俊義 サイトメトリーリサーチ 22 (2), 21-25, 2012

<p>癌幹細胞は化学療法などに対し抵抗性を示し，癌の難治性と再発，進展に関与しているとされる。癌幹細胞に対する治療戦略としての腫瘍融解ウイルス療法の効果を検討した。胃癌細胞株から癌幹細胞様形質を呈するCD133 陽性細胞を分離し，これを胃癌幹細胞モデルとした。従来治療に抵抗性を示すCD133 陽性胃癌細胞にも我々の開発したテロメラーゼ特異的腫瘍融解ウイルス（Telomelysin）は効率的に細胞…

DOI 医中誌 参考文献18件

佐々木 剛, 田澤 大, 長谷井 嬢, 国定 俊之, 吉田 晶, 橋本 悠里, 矢野 修也, 吉田 亮介, 宇野 太, 香川 俊輔, 森本 裕樹, 浦田 泰生, 藤原 俊義, 尾﨑 敏文 岡山医学会雑誌 124 (2), 105-110, 2012

...最後に, OBP-301に感受性を認めなかったCAR陰性細胞株に対してOBP-405を用いて検討し, OBP-405が有効に作用することを確認した.　OBP-301やOBP-405を用いたウイルス療法は, 骨・軟部肉腫に対する新たな治療法となる可能性がある....

DOI 機関リポジトリ Web Site ほか1件 参考文献11件

Tomioka Sachiko, Aigaki Toshiro, Matsuo Takashi Genes & Genetic Systems 87 (5), 323-329, 2012

...Genes encoding two odorant-binding proteins, <i>Obp57d</i> and <i>Obp57e</i>, were identified to be involved in the behavioral adaptation of <i>Drosophila sechellia</i> to its host plant....

DOI Web Site Web Site ほか1件 参考文献20件

F. Siegismund, V. Romanova, A. Köhl, D. Stammer Journal of Geophysical Research: Oceans 116 (C7), C07021-, 2011-07

...Based on resulting uncertainties, a new OBP product is being produced by merging all three data sets....

DOI Web Site Web Site ほか2件 被引用文献1件

Fujiwara Toshiyoshi Acta Medica Okayama 65 (3), 151-162, 2011-06

...We constructed an attenuated adenovirus 5 vector (Telomelysin, OBP-301), in which the hTERT promoter element drives expression of E1 genes....

DOI 機関リポジトリ PubMed ほか1件

Camille Meslin, Fanny Brimau, Patricia Nagnan-Le Meillour, Isabelle Callebaut, Géraldine Pascal, Philippe Monget BMC Evolutionary Biology 11 (1), 148-, 2011-05-28

...<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>SAL1 (salivary lipocalin) is a member of the OBP (Odorant Binding Protein) family...

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Pranjal Bharali, Bolin Kumar Konwar Applied Biochemistry and Biotechnology 164 (8), 1444-1460, 2011-04-06

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Tsuyoshi Sasaki, Hiroshi Tazawa, Jo Hasei, Toshiyuki Kunisada, Aki Yoshida, Yuuri Hashimoto, Shuya Yano, Ryosuke Yoshida, Futoshi Uno, Shunsuke Kagawa, Yuki Morimoto, Yasuo Urata, Toshifumi Ozaki, Toshiyoshi Fujiwara Clinical Cancer Research 17 (7), 1828-1838, 2011-03-31

...OBP-301 antitumor effects were assessed using orthotopic tumor xenograft models. The fiber-modified OBP-301 (termed OBP-405) was used to confirm an antitumor effect on OBP-301–resistant sarcomas....

DOI PDF 被引用文献22件 参考文献50件

T. Schöne, W. Pandoe, I. Mudita, S. Roemer, J. Illigner, C. Zech, R. Galas Natural Hazards and Earth System Sciences 11 (3), 741-749, 2011-03-09

...., 2009) combines GPS technology and ocean bottom pressure (OBP) measurements....

DOI PDF 被引用文献1件

近藤 功庸, 山本 康貴, 愼 鏞光 農林業問題研究 47 (1), 150-153, 2011

...We calculate the input-based productivity (IBP) index and output-based productivity (OBP) index. The results suggest that Korea’s rice productivity has stagnated....

DOI 日本農学文献記事索引 Web Site 被引用文献1件 参考文献9件

黒田 新士, 藤原 俊哉, 白川 靖博, 山崎 泰源, 矢野 修也, 宇野 太, 田澤 大, 橋本 悠里, 渡辺 雄一, 野間 和広, 浦田 泰生, 香川 俊輔, 藤原 俊義 岡山医学会雑誌 123 (2), 103-109, 2011

...mutated）の活性化が抑制され結果的にDNA修復機構が阻害される．我々はOBP-301と放射線との併用が強力な相乗効果を生み出すことをマウスの皮下腫瘍モデルおよび食道癌同所性モデルにおいて証明した．これらの結果はOBP-301が将来有望な放射線増感剤となり得ることだけでなく，E1B55kDaタンパクを産生する腫瘍融解アデノウイルス製剤と放射線との併用が悪性腫瘍に対する有力な治療戦略となり得ることを...

DOI 機関リポジトリ Web Site ほか1件 参考文献22件

MAO Zhiwei, YUAN Kewei, WANG Xianmin IEICE Transactions on Communications E94-B (2), 508-514, 2011

...Simulation results are presented to demonstrate efficacy of the proposed algorithms in joint PICR, OBP, and PAPR reduction....

DOI Web Site 参考文献16件

Park Sung-Ji, Park Jeong Bae, Choi Dong-Ju, Youn Ho Joong, Park Chang Gyu, Ahn Young Keun, Shin Joon-Han, Kim Dong Woon, Rim Se Joong, Bae Jang Ho, Park Hyun Young, The Korean Hypertension Research Network Circulation Journal 75 (2), 357-365, 2011

...The purpose of this study is to present, within the group of patients with well-controlled office BP (OBP), the clinical predictors of MH and to evaluate the gap (ie, the `mask effect' (ME)) between OBP...

DOI Web Site 医中誌 被引用文献4件 参考文献54件

尾崎 俊也, 岡崎 誠 超音波検査技術抄録集 36 (0), S126-S126, 2011

DOI

Gunjan H Arya, Allison L Weber, Ping Wang, Michael M Magwire, Yazmin L Serrano Negron, Trudy F C Mackay, Robert R H Anholt Genetics 186 (4), 1475-1485, 2010-12-01

...We observed polymorphisms in Obp8a, Obp19a, Obp19b, and Obp19c associated with variation in olfactory responses and polymorphisms in Obp19d associated with variation in life span....

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Shinji Kuroda, Toshiya Fujiwara, Yasuhiro Shirakawa, Yasumoto Yamasaki, Shuya Yano, Futoshi Uno, Hiroshi Tazawa, Yuuri Hashimoto, Yuichi Watanabe, Kazuhiro Noma, Yasuo Urata, Shunsuke Kagawa, Toshiyoshi Fujiwara Cancer Research 70 (22), 9339-9348, 2010-11-14

...Thus, tumor cells infected with OBP-301 could be rendered sensitive to ionizing radiation....

DOI PDF 被引用文献23件

Jyunichiro Yasukawa, Sachiko Tomioka, Toshiro Aigaki, Takashi Matsuo Gene 467 (1-2), 25-34, 2010-11

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Yang Mao, Xianzhong Xu, Wei Xu, Yuko Ishida, Walter S. Leal, James B. Ames, Jon Clardy Proceedings of the National Academy of Sciences 107 (44), 19102-19107, 2010-10-18

...The odorant binding proteins (OBPs) in the female's antenna play a crucial, if yet imperfectly understood, role in sensing oviposition cues....

DOI Web Site 被引用文献2件

G. B. Mitchell, M. E. Clark, R. Lu, J. L. Caswell Veterinary Pathology 48 (6), 1054-1060, 2010-09-08

...Functional studies showed no effect of OBP on in vitro growth of Escherichia coli or Mannheimia haemolytica under iron-replete or iron-depleted conditions, nor did OBP opsonize bacteria for an enhanced...

DOI Web Site Web Site 被引用文献1件

Don P. Chambers, Josh K. Willis Journal of Atmospheric and Oceanic Technology 27 (8), 1395-1402, 2010-08-01

...globally with OBP computed from altimetry corrected for steric variations from Argo floats from January 2005 to December 2007....

DOI PDF 被引用文献1件

Huang, P, Kaku, H, Chen, J, Kashiwakura, Y, Saika, T, Nasu, Y, Urata, Y, Fujiwara, T, Watanabe, M, Kumon, H Cancer Gene Therapy 17 (7), 484-491, 2010-07

...The cell-killing effect of OBP-301 was confirmed in vitro in the RENCA cancer cells....

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Ryo Sakai, Shunsuke Kagawa, Yasumoto Yamasaki, Toru Kojima, Futoshi Uno, Yuuri Hashimoto, Yuichi Watanabe, Yasuo Urata, Noriaki Tanaka, Toshiyoshi Fujiwara Molecular Cancer Therapeutics 9 (6), 1884-1893, 2010-06-01

...adenoviral E1 from coinfected OBP-301 in trans....

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Cecilia Peralta‐Ferriz, James Morison Geophysical Research Letters 37 (10), 2010-05

...We derive a simple model of OBP response to runoff and precipitation minus evaporation (P‐E) that agrees in phase with the observations and is 10% larger.</jats:p>...

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P Huang, H Kaku, J Chen, Y Kashiwakura, T Saika, Y Nasu, Y Urata, T Fujiwara, M Watanabe, H Kumon Cancer Gene Therapy 17 (7), 484-491, 2010-02-19

DOI PDF Web Site 被引用文献4件