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Kojima Misaki, Degawa Masakuni Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 47 (3), 606-610, 2024-03-08

...Furthermore, testosterone propionate (TP)-treatment of castrated males and intact females restored and changed, respectively, these mRNA levels to those of intact males....

DOI Web Site PubMed 参考文献18件

Kojima Misaki, Suto Jun-ichi, Degawa Masakuni Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 47 (2), 383-388, 2024-02-08

...involved in testosterone biosynthesis process and by differences in the levels of testosterone released from testes....

DOI Web Site PubMed 参考文献23件

入路, 光雄, 本郷, 悠貴, 風藤, 行紀, 米田, 道夫 General and Comparative Endocrinology 347 114423-, 2024-02-01

...Hsd17b12a and Hsd17b12b catalyzed the conversion of androstenedione (AD) to testosterone (T) and estrone (E1) to E2....

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丹羽 俊朗 薬学雑誌 144 (2), 197-202, 2024-02-01

...Regarding the CYP3A subfamily, the effects of various compounds including endogenous steroid hormones on the 6β-hydroxylation of steroid hormones, such as testosterone, progesterone, and cortisol, were...

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清永 康平, 松田 貴雄, 南 達也 日本臨床スポーツ医学会誌 32 (1), 143-153, 2024-01-31

<p>（緒言）男子では身長増加に伴う循環血液量の増加に伴い，希釈性貧血が生じ，女子では月経による失血にて貧血が生じると考えられてきた．これまで内分泌的成熟による影響を考慮されたものがなく，スポーツを行う児童・生徒についてphase 毎に貧血に関わる鉄欠乏の状態を観察した．</p><p>（方法）9 歳から17 歳のスポーツ活動を行う男子209 名，女子140 名の計349 …

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Ye Sha, Huang Yepei, Lu Yi, Li Xiaoyan, Ye Meiling, Lu Hongyu, Shi Junhua, Huang Jian, Cai Hong Endocrine Journal 71 (1), 45-54, 2024

...Liquid chromatography-tandem mass spectrometry was used to measure androgen indicators, including testosterone, sex hormone-binding globulin (SHBG), free testosterone (FT), dihydrotestosterone (DHT), androstenedione...

DOI Web Site PubMed 参考文献33件

ODA Kaede, YOSHIDA Maya, IRSHAD Abdul Razaq, KANAZAWA Tomomi, TAKAHASHI Toru Journal of Reproduction and Development 70 (1), 25-29, 2024

...The levels of estrogens, including equilin, estrone and estardiol-17β exhibited a dose-dependent increase in fluorescence counts, whereas other steroids, such as progesterone, testosterone, and cortisol...

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Wu Jiao, Zhao Yinan, Zhao Shan, Gao Jinglin, Wang Shijie Food Science and Technology Research advpub (0), 2024

...In this study, we evaluated the inhibitory effects of extracts of bee bread from <i>L. flavibasis</i> (BBLF) on testosterone propionate (TP)-induced BPH in mice by prostate index, histopathological examination...

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Takehara Mai, Kyakuno Mitsuki, Okamoto Kazuko, Tazawa Ichiro, Furuno Nobuaki, Furumitsu Megumi, Ukena Kazuyoshi, Imamura Takuya, Takeuchi Takashi, Hayashi Toshinori Endocrine Journal 71 (2), 181-191, 2024

...Removal of the testes reduced blood testosterone levels. The body weight and abdominal girth of the newts were increased compared with normal male newts....

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大崎 雄介, 白川 仁 日本栄養・食糧学会誌 77 (2), 103-108, 2024

<p>ビタミンKは特定のタンパク質の翻訳後修飾 (Gla化) を介して血液凝固や骨恒常性などに寄与する一方で, 脳や精巣などのGla化活性が低い組織にも高濃度で分布するが, その意義は不明であった。我々は遺伝子発現を網羅的に解析した結果から, ビタミンKが抗炎症作用を有していることを見出し, その機序には核内因子<i>κ</i>B (NF<i>κ</i>B) …

DOI Web Site 参考文献17件

Shirakawa Tomoya, Fink Julius, Hotta Zen-u, Shimada Yosuke, Lu Yan, Du Junhua, Matsushita Kazuhito, Hori Satoshi, Ide Hisamitsu, Horie Shigeo Endocrine Journal 71 (3), 265-272, 2024

...The participants consisted of 12,547 outpatients, whose serum testosterone level was measured....

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Yamamura Yoshiko, Fukami Maki, Matsuyama Misayo, Sawada Hirotake Ｃｌｉｎｉｃａｌ　Ｐｅｄｉａｔｒｉｃ　Ｅｎｄｏｃｒｉｎｏｌｏｇｙ 33 (1), 17-22, 2024

...Only the older brother had prolactin deficiency and testicular growth without elevated testosterone levels....

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Nakamichi Tatsuya, Kawamura Tomoyuki, Nishigaki Satsuki, Odagiri Shino, Yuyama Yoshihiko, Nishikawa-Nakamura Naoko, Hotta Yuko, Hamazaki Takashi Ｃｌｉｎｉｃａｌ　Ｐｅｄｉａｔｒｉｃ　Ｅｎｄｏｃｒｉｎｏｌｏｇｙ 33 (2), 59-65, 2024

...LH/FSH ratio (p = 0.04) and total testosterone levels (p = 0.03) were significantly higher in the oligomenorrhea group than in the non-oligomenorrhea group....

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Kanno Junko, Miura Akinobu, Kawashima Sayaka, Shima Hirohito, Suzuki Dai, Kamimura Miki, Fujiwara Ikuma, Kamimura Masayuki, Uematsu Mitsugu, Kudo Masataka, Kikuchi Atsuo Endocrine Journal advpub (0), 2024

...There are no other reports on the long-term effects of testosterone treatment for the SCA....

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坂本 佳奈, 伊方 敏勝, 茅嶋 理絵, 水谷 望, 西村 祐紀, 増口 信一 日本形成外科学会会誌 43 (12), 739-744, 2023-12-20

...Alongside the potential need for testosterone replacement therapy due to trauma-induced hypogonadism, psychological support remains crucial.</p>...

DOI

松田 貴雄, 清永 康平, 久保 徳彦, 松本 善企, 内田 和宏 日本臨床スポーツ医学会誌 31 (3), 527-533, 2023-08-31

<p>（目的）大分県スポーツ優秀指定選手のメディカルチェック結果から高校生女子スポーツ選手の貧血，鉄欠乏の状況を検討した．</p><p>（方法）高校生女子スポーツ選手162 名の血色素量の値から四分位区分して血液検査の結果を検討した．</p><p>（結果）血色素量の平均値・中央値は12.9g/dl で一般女性平均より低かった．血色素量での第1 四分位群は第4 …

DOI Web Site 医中誌

松井 崇, 船橋 大介, 内沢 彰子, 近藤 衣美, 下山 寛之, 平岡 拓晃, 増地 克之, 岡田 弘隆 武道学研究 56 (Supplement), S_54-S_54, 2023-08-26

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Ohkuma Mahito, Maruyama Takuma, Ishii Toshiyuki, Igarashi Nozomi, Azuma Keiko, Inoue Tatsuya, Obata Ryo, Miyachi Ei-ichi, Kaneda Makoto 日医大誌 90 (4), 333-345, 2023-08-25

...<b>Conclusions: </b>Progesterone, but not estrogen or testosterone, activated glutamate release in the mouse retina....

DOI Web Site PubMed 参考文献52件

Kaneko Tomoko, Kumagai Hiroshi, Yoshikawa Toru, Tsujimoto Takehiko, Miyauchi Takashi, Tanaka Kiyoji, Maeda Seiji The Journal of Physical Fitness and Sports Medicine 12 (4), 101-106, 2023-07-25

...Before and after the intervention, we measured the circulating levels of estradiol and testosterone and calculated the estradiol/testosterone ratio in overweight and obese men....

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Toshiro Niwa, Misaki Tani, Anna Suzuki, Mizuho Murakami Drug Metabolism and Bioanalysis Letters 16 (2), 73-80, 2023-07

...The inhibition strength of azole antifungal agents against cortisol 6β-hydroxylation catalyzed by all CYP3A subfamilies was similar to that of testosterone 6β-hydroxylation....

DOI Web Site Web Site 被引用文献1件

板倉 厳一郎 関西大学東西学術研究所紀要 56 A29-A45, 2023-07-01

Though often pigeonholed as a spy novel, John le Carre’s A Most Wanted Man (2008) provides an insight into the post-9/11 intellectual climate. As if to confirm the author’s place on the political …

DOI 機関リポジトリ HANDLE ほか1件

Chad Tang, Alexander D. Sherry, Cara Haymaker, Tharakeswara Bathala, Suyu Liu, Bryan Fellman, Lorenzo Cohen, Ana Aparicio, Amado J. Zurita, Alexandre Reuben, Enrica Marmonti, Stephen G. Chun, Jay P. Reddy, Amol Ghia, Sean McGuire, Eleni Efstathiou, Jennifer Wang, Jianbo Wang, Patrick Pilie, Craig Kovitz, Weiliang Du, Samantha J. Simiele, Rachit Kumar, Yerko Borghero, Zheng Shi, Brian Chapin, Daniel Gomez, Ignacio Wistuba, Paul G. Corn JAMA Oncology 9 (6), 825-, 2023-06-01

...Combination of MDT with intermittent hormone therapy may allow for excellent disease control while facilitating prolonged eugonadal testosterone intervals....

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Kuraoka Sakiko, Iwamuro Masaya, Satomi Takuya, Yamazaki Tatsuhiro, Hamada Kenta, Kono Yoshiyasu, Kanzaki Hiromitsu, Kato Hironari, Otsuka Fumio, Okada Hiroyuki Acta Medica Okayama 77 (3), 235-241, 2023-06

...At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone....

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Wang Jing, Pan Xinyao, Zhou Jing, Li Xin, Sun Yan, Wang Ling Drug Discoveries & Therapeutics 17 (2), 87-94, 2023-04-30

<p>Diminished ovarian reserve (DOR) refers to the decline in fertility caused by the loss of normal ovarian function. DOR is associated with adverse reactions to ovarian stimulation during <i>in …

DOI Web Site PubMed 参考文献68件

清永 康平, 南 達也, 松田 貴雄 日本臨床スポーツ医学会誌 31 (2), 324-333, 2023-04-30

<p>（緒言）これまで低エストラジオール（E2）が女性アスリートのスポーツ障害，特に疲労骨折の危険因子とされているが，今回，男性ホルモンである総テストステロン（T）低値が危険因子であるかどうかを検討した．</p><p>（方法）2019 年9 月から2021 年8 月までスポーツ障害で受診した8 歳から19 歳の女子スポーツ選手の105 …

DOI Web Site 医中誌

Andrea Zovi, Francesco Ferrara, Roberto Langella, Fabiola Cavallaro, Antonio Vitiello Reviews in Medical Virology 33 (4), 2023-04-16

...Men, due to higher production of Testosterone (TLT), are more vulnerable than females....

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Koichi Furukawa, Kogo Takamiya, Yuhsuke Ohmi, Robiul H. Bhuiyan, Orie Tajima, Keiko Furukawa FEBS Open Bio 13 (9), 1615-1624, 2023-04-06

...Although serum levels of testosterone in the male mice were extremely low, testosterone accumulated in the interstitial tissues, including Leydig cells, and seemed not to be transferred into the seminiferous...

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吉田 智紀, 楠田 哲士, 下川 優紀, 織田 拓 日本野生動物医学会誌 28 (1), 25-34, 2023-04-05

<p>　飼育下シャモア（<i>Rupicapra rupicapra</i>）において，糞中のステロイドホルモン動態から，雌雄の繁殖季節や雌の発情周期などの繁殖生理を明らかにすることを目的とした。雄2頭と雌1頭から糞を採取し，雄ではテストステロン（T）およびアンドロステンジオン（AD）を，雌ではプロジェステロン（P4），エストラジオール-17β（E2），エストロン（E1）およびコルチゾールを酵素…

DOI Web Site Web Site ほか1件 参考文献23件

R Matsumoto, K Murakumo, R Nozu, D Acuña-Marrero, JR Green, SJ Pierce, CA Rohner, H Reyes, SM Green, ADM Dove, ML Torres, AR Hearn Endangered Species Research 50 125-131, 2023-03-23

...Additionally, 3 steroid hormones (estradiol, testosterone, and progesterone) were analyzed in blood plasma from 6 female sharks (11-12 m TL)....

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Kitajima, Michio, Kajimura, Itsuki, Kitajima, Yuriko, Murakami, Naoko, Matsumura, Asako, Matsumoto, Kanako, Harada, Ayumi, Hasegawa, Yuri, Miura, Kiyonori Journal of Ovarian Research 16 (1), 52-, 2023-03-15

...Markedly elevated serum testosterone, LH, and AMH levels were noted. Mild hirsutism and clitoromegaly were presented....

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Aono, Kentaro, 青野, 健太郎 福岡大学薬学集報 23 51-58, 2023-03

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Kojima Misaki, Degawa Masakuni, Nemoto Kiyomitsu Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 46 (3), 482-487, 2023-03-01

...level of <i>CUX2</i> mRNA were detected in the liver of both breeds, and levels were significantly decreased in males by castration and increased in castrated males and intact females by administering testosterone...

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Hiroshi Yoshida, Masaya Uno, Keisuke Ogimoto, Mayumi Kobayashi-Kato, Yasuhito Tanase, Mitsuya Ishikawa, Tomoyasu Kato International Journal of Gynecological Pathology 42 (3), 308-314, 2023-02-21

...A 30-yr-old transgender man with an intrauterine tumor, an ovarian mass, and a 2-yr history of testosterone use was referred to us for treatment....

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HASUNUMA, Kansuke, NAKATA, Mariko, 小川, 園子 筑波大学心理学研究 61 1-23, 2023-02-17

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Takashi Yazawa, Mohammad Sayful Islam, Yoshitaka Imamichi, Hiroyuki Watanabe, Kazuhide Yaegashi, Takanori Ida, Takahiro Sato, Takeshi Kitano, Shigenori Matsuzaki, Akihiro Umezawa, Yuki Muranishi Animals 13 (4), 622-, 2023-02-10

...Because human HSD17B1 showed strong activity for the conversion of androstenedione into testosterone, similar to HSD17B1/Hsd17b1 in other species, we also discuss the biological significance of human placental...

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齋藤, 昇 岡山大学農学部学術報告 112 19-22, 2023-02-01

...Several experiments involving electrical lesion, testosterone implantation, and the detection of the immediately-early gene expression in birds expressing copulatory behavior suggested that nST and nucleus...

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Nobuyuki Kutsukake, Migaku Teramoto, Seijiro Honma, Yusuke Mori, Takafumi Ishida, Toshikazu Hasegawa acta ethologica 26 (1), 45-58, 2023-02

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Mengwei Li, Noriyoshi Usui, Shoichi Shimada International Journal of Molecular Sciences 24 (3), 2203-, 2023-01-22

...The present review examined studies that focused on the association between prenatal testosterone exposure and ASD development, as well as sex-specific behaviors in individuals with ASD....

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Ramiro Manzano-Nunez, Marta Santana-Dominguez, Jesus Rivera-Esteban, Clara Sabiote, Elena Sena, Juan Bañares, Frank Tacke, Juan M. Pericàs Journal of Clinical Medicine 12 (3), 856-, 2023-01-20

...Meta-regression showed that rises in NAFLD prevalence were mediated through increases in metabolic syndrome prevalence and higher levels of HOMA-IR, free androgen index, and total testosterone....

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Kento Ikegawa, Yukihiro Hasegawa Frontiers in Endocrinology 14 2023-01-20

...The adrenal gland is considered an important organ in 11KT production because CYP11B1, which catalyzes testosterone to 11OHT, is expressed in the adrenal glands....

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Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Jae Young Jang, Ha-Na Lee Cancer Research and Treatment 55 (1), 196-218, 2023-01-15

...Previously, we reported that endogenous and exogenous testosterone are associated with colorectal cancer (CRC) development and submucosal invasion....

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Indrashis Bhattacharya, Souvik Dey Frontiers in Endocrinology 13 1086276-, 2023-01-04

...<jats:p>Leydig cells (Lc) reside in the interstitial compartment of the testis and are the target of Luteinising hormone (LH) for Testosterone (T) production, thus critically regulates male fertility....

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麻生, 敬子 Endocrine journal 70 (1), 59-67, 2023-01

type:Article

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Tatsuya Higashi, Saki Aso, Hiroaki Horisaki, Takenori Ito, Sakurako Tanaka, Shoichi Nishimoto-Kusunose, Shoujiro Ogawa, Kazuhiko Kato, Hisamitsu Ide Clinica Chimica Acta 538 157-163, 2023-01

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Masahiro Uchida, Teruaki Iwamoto, Kazumitsu Yamasaki, Fumiko Kariya, Shoko Konishi Reproductive Medicine and Biology 22 (1), 2023-01

...Testosterone showed weak negative correlations with the 2D:4D ratio in the left (<jats:italic>r</jats:italic> = −0.142, <jats:italic>p</jats:italic>  = 0.058) and right (<jats:italic>r</jats:italic> = ...

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Françoise Diaz-Rojas, Michiko Matsunaga, Yukari Tanaka, Takefumi Kikusui, Kazutaka Mogi, Miho Nagasawa, Kohei Asano, Nobuhito Abe, Masako Myowa Journal of Cognitive Neuroscience 35 (3), 396-420, 2023

...We measured oxytocin and testosterone, paternity-related psychological traits, and neural response to infant-interaction videos using fMRI in first-time fathers and childless men at three time points (...

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Akisada Hiroko, Hasegawa Mari, Ishihara Takashi, Akisada Naohiro, Ochi Satoshi, Nogami Keiji Ｃｌｉｎｉｃａｌ　Ｐｅｄｉａｔｒｉｃ　Ｅｎｄｏｃｒｉｎｏｌｏｇｙ 32 (2), 90-97, 2023

...All three girls with a CED of 9–11 g/m² had primary hypogonadism, and the boy with a CED of 24 g/m² had high LH and FSH levels, suggesting testosterone deficiency...

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Ide Hisamitsu Endocrine Journal 70 (7), 655-662, 2023

...Age-related testosterone decline is closely associated with sarcopenia and muscle deterioration, while testosterone decline is linked with the etiology and prevention of diseases such as angina pectoris...

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Ishikawa Keisuke, Tsujimura Akira, Miyoshi Miho, Miyoshi Yuto, Ogasa Taiki, Hiramatsu Ippei, Uesaka Yuka, Nozaki Taiji, Shirai Masato, Kobayashi Kazuhiro, Horie Shigeo Endocrine Journal 70 (9), 883-890, 2023

...This study comprised 110 men with low testosterone concentration of <3.0 ng/mL who underwent testosterone replacement treatment....

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Watanabe Tetsuhiro, Okabe Saori, Sakamoto Shohei Endocrine Journal 70 (10), 1015-1021, 2023

...The blood testosterone level normalized at 41 weeks....

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石阪 賢太, 吉江 幹浩, 津留 涼也, 安曇 麻奈, 草間 和哉, 田村 和広 日本薬理学会年会要旨集 97 (0), 2-B-P-089-, 2023

...Treatment with butyrate suppressed the db-cAMP-stimulated testosterone production....

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坂本 多穗, 清水 聡史, 児玉 昌美, 黒川 洵子 日本薬理学会年会要旨集 97 (0), 2-B-S35-2-, 2023

...In vitro analysis shows that estradiol, but not testosterone, enhances gene expression....

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Nagata Chisato, Wada Keiko, Yamakawa Michiyo, Nakashima Yuma, Hayashi Makoto, Takeda Noriyuki, Yasuda Keigo Endocrine Journal 70 (3), 267-273, 2023

...Shorter sleep duration was significantly associated with the higher total, bioavailable, and free testosterone levels....

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Shirai Masato, Tsujimura Akira, Mizushima Kazuhiko, Tsuru Takamitsu, Kurosawa Makoto, Kure Akimasa, Uesaka Yuka, Nozaki Taiji, Kobayashi Kazuhiro, Horie Shigeo Endocrine Journal 70 (4), 403-409, 2023

...<p>Late-onset hypogonadism (LOH) is generally treated with testosterone replacement therapy....

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GOTO Akira, YOSHIDA Nanako, NAKADA Ken, INOUE Yoichi, HISAEDA Keiichi, INABA Toshio, DOMOTO Nanami, ISHIGURO Yuki, ITOH Megumi, TAKAHASHI Eiji, SASAKI Motoki, MATSUI Motozumi Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 85 (5), 551-556, 2023

...The testosterone levels are a useful indicator of the immunocastration effect on cryptorchid bulls....

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Maeda-Usui Ayaka, Sato Takeshi, Nakano Satsuki, Kusakawa Moe, Kin Takane, Takahashi Nobuhiro, Motojima Yukiko, Asanuma Hiroshi, Hida Mariko, Ishii Tomohiro, Kuroda Tatsuo, Hasegawa Tomonobu Ｃｌｉｎｉｃａｌ　Ｐｅｄｉａｔｒｉｃ　Ｅｎｄｏｃｒｉｎｏｌｏｇｙ 32 (2), 119-122, 2023

...The parents assigned the infant as male, considering the 46,XY karyotype, normal testosterone secretion, possible male identity, and the natural history of PHS....

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Motohashi Masaya, Wempe Michael F., Mutou Tomoko, Okayama Yuya, Kansaku Norio, Takahashi Hiroyuki, Ikegami Masahiro, Asari Masao, Wakui Shin Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃａｌ　Ｓｃｉｅｎｃｅｓ 48 (6), R1-, 2023

...<p><b><i>Editor’s Announcement</i></b><br><br><b><i>In utero</i>-exposed di(<i>n</i>-butyl) phthalate induce dose dependent, age-related changes of morphology and testosterone-biosynthesis enzymes/associated...

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DOLIN Aurelia, SCHWEIGER Peter, WASELAU Martin, EGERBACHER Monika, WALTER Ingrid Ｊｏｕｒｎａｌ　ｏｆ　Ｅｑｕｉｎｅ　Ｓｃｉｅｎｃｅ 34 (2), 37-46, 2023

...classification, progression, and prognosis in human SCSTs, on an exemplary grapefruit-size equine GCT within the left ovary of a 13-year-old mare with stallion-like behavior and elevated testosterone...

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Narita Chisato, Takubo Noriyuki, Sammori Manami, Matsumura Yuko, Shimura Kazuhiro, Ozaki Rie, Haruna Hidenori, Narumi Satoshi, Ishii Tomohiro, Hasegawa Tomonobu, Shimizu Toshiaki Ｃｌｉｎｉｃａｌ　Ｐｅｄｉａｔｒｉｃ　Ｅｎｄｏｃｒｉｎｏｌｏｇｙ 32 (4), 235-238, 2023

...Gonadotropin levels were high, whereas testosterone levels were low. A pelvic magnetic resonance imaging (MRI) revealed a hypoplastic uterus; however, no gonads could be identified....

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RAWAN Ahmad Farid, LANGAR Hikmatullah, MUNETOMO Maho, YAMAMOTO Yuki, KAWANO Kohei, KIMURA Koji Journal of Reproduction and Development 69 (6), 337-346, 2023

...Additionally, we assessed the influence of IGF-1 on androstenedione (A4), progesterone (P4), and testosterone (T) production in TCs....

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宮宗 秀伸, 高野 海哉, 吉岡 広陽, 松野 義晴, 李 忠連, 倉升 三幸, 小川 夕輝, 横田 理, 伊藤 正裕 日本毒性学会学術年会 50.1 (0), O3-33-, 2023

...We observed a dose-dependent increase in serum CORT levels on PND 10, and serum testosterone levels were significantly increased only in high-dosed-CORT mice....

DOI

Ariyasu Daisuke, Nagamatsu Fusa, Aso Keiko, Akiba Kazuhisa, Hasegawa Yukihiro Endocrine Journal 70 (1), 59-67, 2023

...<p>5α-reductase type 2 (5αRD2) deficiency is a 46,XY disorder of sex development caused by impaired conversion of testosterone (T) to dihydrotestosterone (DHT)....

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Bao Zhouzhou, He Wei, Di Wen, Gao Hua Endocrine Journal 70 (3), 275-280, 2023

...She had a remarkable elevation of total testosterone, dehydroepiandrosterone sulfate and androstenedione. Pelvic ultrasonography showed normal morphology of the uterus and bilateral ovaries....

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永井 寛子, 佐藤 花純, 野村 収作 日本感性工学会論文誌 22 (2), 129-134, 2023

...In this study, we developed a protocol for quantitative analysis of three sex hormones, which are testosterone, progesterone, and estradiol, simultaneously from a single fingernail sample....

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Gallegos-Reyes Marco A, Antaño-Martínez Alejandro R, Alcaraz-Contreras Yolanda, Alegría-Torres Jorge A, Robles Juvencio, Yáñez-Barrientos Eunice, Martinez-Alfaro Minerva Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃａｌ　Ｓｃｉｅｎｃｅｓ 48 (8), 481-486, 2023

...Whereas melatonin therapy reduced serum testosterone to levels lower than those in control rats, silymarin increased serum testosterone to levels higher than those in controls....

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森 大輝, 満倉 靖恵, 沼田 洋輔, 林田 健一郎 日本薬理学会年会要旨集 97 (0), 2-B-P-041-, 2023

...Although testosterone, the primary male hormone secreted by the testicles, has been demonstrated to increase pain thresholds in humans and animals, whether testicle size affects pain thresholds is unknown...

DOI Web Site

溝上 顕子, 杜 海妍, 佐野 朋美, 山脇 洋輔, 自見 英治郎, 兼松 隆 日本薬理学会年会要旨集 97 (0), 2-B-P-019-, 2023

...Furthermore, co-stimulation with Aβ and testosterone amplified autophagic vacuoles, strengthening the link between testosterone and Aβ-induced autophagy....

DOI Web Site

Zheng Tian, Yagi Masayuki, Ogura Mari, Terasaka Takeshi, Kuwabara Shoji, Yonei Yoshikazu Glycative Stress Research 9 (4), 206-220, 2022-12-31

...insulin: IRI, HbA1c, fasting plasma glucose: FPG, skin AGE fluorescence: SAF), and endocrine-related blood tests (insulin-like growth factor-I: IGF-I, dehydroepiandrosterone-sulfate: DHEA-s, estradiol: E2, testosterone...

DOI Web Site 医中誌

Hikari Koyasu, Hironobu Takahashi, Ikuto Sasao, Saho Takagi, Miho Nagasawa, Takefumi Kikusui Animals 13 (1), 146-, 2022-12-30

...In addition, individual male cats with low testosterone levels were more likely to interact with an experimenter....

DOI Web Site 参考文献48件

Alan L. Ho, Nathan R. Foster, Alex J. Zoroufy, Jordan D. Campbell, Francis Worden, Katharine Price, Douglas Adkins, Daniel W. Bowles, Hyunseok Kang, Barbara Burtness, Eric Sherman, Roscoe Morton, Luc G.T. Morris, Zaineb Nadeem, Nora Katabi, Pamela Munster, Gary K. Schwartz Journal of Clinical Oncology 40 (36), 4240-4249, 2022-12-20

...Total and free testosterone levels increased by a mean of 61.2% and 48.8%, respectively, after enzalutamide....

DOI Web Site 被引用文献2件

Congshun Ma, Qianru Xiang, Ge Song, Xuefei Wang Frontiers in Pharmacology 13 2022-12-16

...Some studies have shown that serum testosterone (T), luteinizing hormone (LH), the LH/follicule-stimulating hormone (FSH) ratio, fasting glucose, fasting insulin, HOMA-IR and lipid levels are reduced in...

DOI Web Site 被引用文献1件

Yuki Ishinoda, Asuka Uto, Yoshifumi Yamada, Maki Okazaki, Hidetomo Asada, Seina Wakamatsu, Isao Kurihara, Hironori Shibata, Tomohiro Ishii, Tomonobu Hasegawa, Hiroo Kumagai, Akira Kasuga BMC Endocrine Disorders 22 (1), 2022-12-02

...Additional testing revealed low cortisol, high adrenocorticotropic hormone, and low testosterone and dehydroepiandrosterone sulfate, indicating congenital adrenal hyperplasia....

DOI PDF Web Site 被引用文献1件

二村 吉継 喉頭 34 (2), 108-112, 2022-12-01

...The administration of testosterone, a male hormone, for the treatment of gender incongruence induces physical masculinization, including changing the sound of the voice....

DOI Web Site 参考文献8件

荒木 博賢, 伊藤 克弘, 五十嵐 篤, 三浦 高慶, 宮﨑 有, 三品 睦輝, 奥野 博 泌尿器科紀要 68 (11), 337-343, 2022-11-30

...Serum testosterone level was tested in 20 patients, and five showed testosterone recovery ≥0.5 ng/ml....

DOI HANDLE Web Site ほか1件

Himari Matsusaka, Tao Wu, Kai Furuya, Tomoe Yamada-Kato, Lanlan Bai, Hiroshi Tomita, Eriko Sugano, Taku Ozaki, Tohru Kiyono, Isao Okunishi, Tomokazu Fukuda Scientific Data 9 (1), 2022-11-29

...The testosterone or dihydroxy testosterone (DHT) circulates through the blood, binds to the androgen receptor (AR) in the cytoplasm, and finally enters the nucleus to activate downstream target genes....

DOI PDF Web Site 参考文献17件

Baris Ata, Nathalie Vermeulen, Edgar Mocanu, Luca Gianaroli, Kersti Lundin, Satu Rautakallio-Hokkanen, Juha S Tapanainen, Anna Veiga Human Reproduction Update 29 (2), 177-196, 2022-11-14

...Testosterone levels seem to be lower during and after COVID-19, but long-term data are lacking; disease severity may be associated with testosterone levels....

DOI PDF 被引用文献1件

Hidenobu Miyaso, Kaiya Takano, Kenta Nagahori, Zhong-Lian Li, Shinichi Kawata, Miyuki Kuramasu, Yuki Ogawa, Hirotaka Yoshioka, Yoshiharu Matsuno, Satoshi Yokota, Masahiro Itoh Scientific Reports 12 (1), 2022-11-12

...We observed a dose-dependent increase in serum CORT levels on PND 10, and serum testosterone levels were significantly increased only in high-dosed-CORT mice....

DOI PDF Web Site 参考文献52件

Kota Shiozawa, Misato Maeda, Hsin-Jung Ho, Tomoko Katsurai, Md. Zakir Hossain Howlader, Kimiko Horiuchi, Yumi Sugita, Yusuke Ohsaki, Afifah Zahra Agista, Tomoko Goto, Michio Komai, Hitoshi Shirakawa Nutrients 14 (22), 4761-, 2022-11-10

...<jats:p>Late-onset hypogonadism, a male age-related syndrome characterized by a decline in testosterone production in the testes, is commonly treated with testosterone replacement therapy, which has adverse...

DOI Web Site 参考文献41件

Kumi Hirokawa, Ayaka Kasuga, Kiyoaki Matsumoto, Yasuko Omori, Yukie Masui, Takeshi Nakagawa, Madoka Ogawa, Yoshiko Ishioka, Hiroki Inagaki, Kazunori Ikebe, Yasumichi Arai, Tatsuro Ishizaki, Kei Kamide, Yasuyuki Gondo Geriatrics & Gerontology International 22 (12), 1040-1046, 2022-11-09

...Salivary testosterone concentrations were positively associated with better cognitive performance in older men and women....

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Takashi Yazawa, Takahiro Sato, Takanori Ida Journal of the Endocrine Society 6 (Supplement_1), A718-A719, 2022-11-01

...JSBMB, 2020), we found that porcine AKR1C1 can convert androstenedione into testosterone (T) and is expressed in adrenal, testis and ovary....

DOI PDF

Alaa Ibrahim Ali, Wassan Nori Mohammed Hassan, Sumaya Alrawi Current Women s Health Reviews 18 (4), 2022-11

...body mass index and blood pressure for all besides the blood sampling for estimation of a follicular stimulating hormone, luteinizing hormone, prolactin, estradiol, sex hormone-binding globulin, total testosterone...

DOI Web Site Web Site 被引用文献1件

Kumi Hirokawa, Yasuhito Fujii, Toshiyo Taniguchi, Morihiro Tsujishita Comprehensive Psychoneuroendocrinology 12 100158-, 2022-11

DOI Web Site Web Site 参考文献48件

José Carlos Fernández-García, Rocío Barrios-Rodríguez, Maite Asenjo-Plaza, Bruno Ramos-Molina, María Molina-Vega, Antonio Guzmán-Guzmán, Luis Moreno-León, Elena M. Yubero-Serrano, Francisca Rius-Díaz, Sergio Valdés, Miguel Ángel Martínez-González, José Juan Jiménez-Moleón, Francisco J. Tinahones Metabolism 136 155290-, 2022-11

DOI Web Site Web Site 被引用文献1件

Hibi Hatsuki, Tokoro Mikiko, Sugie Miho, Ohori Tadashi, Sonohara Megumi, Fukunaga Noritaka, Asada Yoshimasa Nagoya Journal of Medical Science 84 (4), 839-847, 2022-11

...The serum zinc concentration did not relate with age, sperm concentration, sperm motility, luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone, and body mass index (BMI)....

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片岡 智哉 薬学雑誌 142 (11), 1129-1136, 2022-11-01

...We have clarified the effects of testosterone on the tissue structure and endothelial function of the corpus cavernosum using castrated rats....

DOI Web Site Web Site ほか1件 参考文献20件

Tomoya Kataoka, Hiroto Ito, Taiki Mori, Yuji Hotta, Akimasa Sanagawa, Yasuhiro Maeda, Yoko Furukawa-Hibi, Kazunori Kimura International Journal of Impotence Research 2022-10-30

DOI PDF Web Site 参考文献31件

David Alarcón-Alarcón, David Cabañero, Jorge de Andrés-López, Magdalena Nikolaeva-Koleva, Simona Giorgi, Gregorio Fernández-Ballester, Asia Fernández-Carvajal, Antonio Ferrer-Montiel Nature Communications 13 (1), 6304-, 2022-10-22

...TRPM8-mediated antinociception effects required the presence of endogenous testosterone in males....

DOI PDF Web Site 被引用文献1件

Kazuyoshi Shigehara, Yuki Kato, Kouji Izumi, Atsushi Mizokami Journal of Clinical Medicine 11 (20), 6202-, 2022-10-20

...Many randomized control studies have also supported the beneficial effect of testosterone replacement therapy (TRT) on muscle volume and strength among men with low to normal testosterone levels....

DOI Web Site 被引用文献1件

Hayato Nomura, Hayato Terayama, Daisuke Kiyoshima, Ning Qu, Kosuke Shirose, Shuhei Tetsu, Shogo Hayashi, Kou Sakabe, Takeshi Suzuki Applied Sciences 12 (20), 10409-, 2022-10-15

...DEX administration did not affect serum testosterone levels, some testicular mRNA related to spermatogenesis, and oxidative stress factors....

DOI Web Site 参考文献48件

Imai Hideyuki, Nishikawa Hiroto, Suzuki Asami, Kodama Eriko, Iida Tatsuya, Mikura Kentaro, Hashizume Mai, Kigawa Yasuyoshi, Tadokoro Rie, Sugisawa Chiho, Endo Kei, Iizaka Toru, Otsuka Fumiko, Nagasaka Shoichiro Internal Medicine 61 (19), 2899-2903, 2022-10-01

...On an examination in our department in May, blood tests showed low gonadotropin and testosterone levels, indicative of secondary hypogonadism....

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Mingying Ma, Tianhao Wu, Gongwei Sun, Sichun Zhang Analytical Biochemistry 653 114719-, 2022-09

DOI Web Site Web Site 被引用文献1件

Tomoya Kataoka, Ayako Fukamoto, Yuji Hotta, Akimasa Sanagawa, Yasuhiro Maeda, Yoko Furukawa-Hibi, Kazunori Kimura Sexual Medicine 10 (5), 100550-100550, 2022-08-05

...kg testosterone; T(25) per week, wherein the rats were subcutaneously injected with 25 mg/kg testosterone per week; and T(100), wherein the rats were subcutaneously injected with 100 mg/kg testosterone...

DOI PDF Web Site ほか1件 参考文献40件

B.M. Clanner‐Engelshofen, L.M. Ständer, T. Steegmüller, T. Kämmerer, L.H. Frommherz, P.‐C. Stadler, A. Gürtler, M. Reinholz Journal of the European Academy of Dermatology and Venereology 36 (12), 2499-2503, 2022-08-04

...Incubation for 30 days with anabolic steroids (testosterone and trenbolone) as well as retinol and retinoic acid (isotretinoin) yielded a reduced mite density....

DOI Web Site Web Site 被引用文献1件

Jan Vollert, Nils Trewartha, Deborah Kemkowski, Alexander Felix Cremer, Peter K. Zahn, Daniel Segelcke, Esther M. Pogatzki‐Zahn European Journal of Pain 26 (9), 1938-1949, 2022-08-02

...The magnitude of CPM and offset effects was weakly influenced by sex and testosterone levels, indicating an area for future research, rather than clinical significance....

DOI Web Site Web Site 被引用文献1件

Yusuke Oe, Shinichi Ogino, Masanori Kobayashi, Hiroyuki Kojima, Takayuki Terukina, Takanori Kanazawa, Hiromu Kondo Journal of Pharmaceutical Sciences 111 (8), 2322-2329, 2022-08

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Mami Kobayashi, Hideaki Yagasaki, Kei Tamaru, Yumiko Mitsui, Takeshi Inukai Endocrinology, Diabetes & Metabolism Case Reports 2022 2022-08-01

...He grew close to his final height, and his testes developed with normal LH, increased FSH, normal testosterone, and reduced AMH corresponding to puberty at 13.5 years of age....

DOI XML XML 参考文献15件

S. Mastromattei, T. Todisco, L. Chioma, G. Ubertini, M. G. Pattumelli, D. Fintini, M. Cappa Journal of Endocrinological Investigation 45 (12), 2377-2384, 2022-07-28

DOI PDF Web Site 被引用文献1件

Hikari Koyasu, Hironobu Takahashi, Moeka Yoneda, Syunpei Naba, Natsumi Sakawa, Ikuto Sasao, Miho Nagasawa, Takefumi Kikusui PLOS ONE 17 (7), e0269589-, 2022-07-27

...Notably, individuals with low cortisol and testosterone concentrations were highly tolerant, making high-density living easy....

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Kehinde S. Olaniyi, Al-amin M. Bashir, Stephanie E. Areloegbe, Isaiah W. Sabinari, Christopher O. Akintayo, Adesola A. Oniyide, Ayodeji Aturamu PLOS ONE 17 (7), e0272124-, 2022-07-26

...</jats:p> </jats:sec> <jats:sec id="sec003"> <jats:title>Results</jats:title> <jats:p>The rat model of PCOS had increased body weight and ovarian weight, 1-hr postload glucose and plasma insulin, testosterone...

DOI Web Site 被引用文献1件

Tanja Restin, Nastassja Byland, Clarissa D. Voegel, Pearl La Marca-Ghaemmaghami, Markus R. Baumgartner, Dirk Bassler, Thomas Kraemer, Tina M. Binz Analytical and Bioanalytical Chemistry 414 (20), 6201-6211, 2022-07-04

...quantification of four eCBs (2-arachidonoylglycerol (2-AG), anandamide (AEA), oleoylethanolamide (OEA), palmitoylethanolamide (PEA)) and five steroid hormones (cortisol, cortisone, androstenedione, progesterone, testosterone...

DOI PDF Web Site 被引用文献1件

Isanna Murro, Giuseppe Lisco, Carmen Di Noia, Luisa Lampignano, Roberta Zupo, Vito Angelo Giagulli, Edoardo Guastamacchia, Vincenzo Triggiani, Giovanni De Pergola Endocrine, Metabolic & Immune Disorders - Drug Targets 22 (8), 798-806, 2022-07

...These inspire a decrease in both total and free testosterone levels in men and FT3 and FT4 levels in women, particularly after a pregnancy....

DOI Web Site Web Site 被引用文献1件

Yusuke Yoshino, Yoshitaka Wakabayashi, Takatoshi Kitazawa Current HIV Research 20 (4), 321-326, 2022-07

...<jats:sec> <jats:title>Background:</jats:title> <jats:p>Recently, male hypogonadism was reported to be prevalent in people living with HIV (PLWH), even in cases diagnosed based on the serum free testosterone...

DOI Web Site Web Site 参考文献21件

Hyun Gyung Lee, Chan Jong Kim Annals of Pediatric Endocrinology & Metabolism 27 (2), 83-89, 2022-06-30

...Recent investigations have reported an alternative ("backdoor") route for DHT formation that bypasses fetal testicular testosterone....

DOI PDF Web Site 被引用文献1件

Qing Li, Li Zhang, Zhengguo Zhang, Yuhan Wang, Chongwen Zuo, Shumin Bo Frontiers in Physiology 13 2022-06-29

...BDNF, VEGF-A, cortisol, testosterone, blood lactic acid were measured and cognitive function was assessed by Stroop test (CWST) and Digital Span test (DST) before, immediately after, and 30 min after HIIT...

DOI Web Site 被引用文献1件

Hideaki Nakatsuji, Tetsuhiko Ikeda, Atsushi Hashizume, Masahisa Katsuno, Gen Sobue, Takashi Nakajima Frontiers in Neurology 13 2022-06-24

...<jats:p>Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's disease, is a rare, slowly progressive, incurable, and hereditary neurodegenerative disease caused by the testosterone-dependent...

DOI Web Site 被引用文献1件

Hallgerdur Lind Kristjansdottir, Dan Mellström, Peter Johansson, Magnus Karlsson, Liesbeth Vandenput, Mattias Lorentzon, Hans Herlitz, Claes Ohlsson, Ulf H. Lerner, Catharina Lewerin Archives of Osteoporosis 17 (1), 85-, 2022-06-23

...Men with anemia had higher serum levels of fibroblast growth factor 23 (iFGF23) (<jats:italic>p</jats:italic> < 0.001) and phosphate (<jats:italic>p</jats:italic> = 0.001) and lower serum levels of testosterone...

DOI PDF Web Site 被引用文献1件

Hiroe Okada, Haruhiko Kanasaki, Tuvshintugs Tumurbaatar, Zolzaya Tumurgan, Aki Oride, Satoru Kyo Reproductive Biology and Endocrinology 20 (1), 2022-06-21

...-1 gene expression by 3.20 ± 0.44-fold; testosterone also increased kisspeptin protein expression....

DOI PDF Web Site 被引用文献1件 参考文献39件

Daniel Dahlberg, Jutta Rummel, Sonia Distante, Gustavo Antonio De Souza, Maria Ekman Stensland, Espen Mariussen, Helge Rootwelt, Øyvind Voie, Bjørnar Hassel Fluids and Barriers of the CNS 19 (1), 45-, 2022-06-04

...Tumor volume correlated with cyst fluid concentrations of growth hormone and testosterone. Survival correlated inversely with cyst fluid concentration of erythropoietin....

DOI PDF Web Site 被引用文献1件

Sofia Cienfuegos, Sarah Corapi, Kelsey Gabel, Mark Ezpeleta, Faiza Kalam, Shuhao Lin, Vasiliki Pavlou, Krista A. Varady Nutrients 14 (11), 2343-, 2022-06-03

...Interestingly, muscle mass and muscular strength were not negatively affected by these reductions in testosterone....

DOI Web Site 被引用文献1件

Toshihisa Komori International Journal of Molecular Sciences 23 (10), 5776-, 2022-05-21

...Osteocalcin (Bglap/Bglap2) is required for the alignment of apatite crystals parallel to the collagen fibers; however, it does not physiologically work as a hormone that regulates glucose metabolism, testosterone...

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Selma Waaijers, Agustini Utari, Rick H. A. van der Doelen, Sultana M. H. Faradz, Renate Hensen‐Lodewijk, Andre J. Olthaar, Paul J. Geutjes, Fred C. Sweep, Hedi L. Claahsen‐van der Grinten, Antonius E. van Herwaarden Clinical Endocrinology 98 (1), 41-48, 2022-05-15

...After starting glucocorticoid treatment, the steroid concentrations in the hair of CAH patients decreased significantly for androstenedione (73%) and testosterone (59%) after 6 months....

DOI Web Site Web Site 被引用文献1件

Ryan D Paulukinas, Clementina A Mesaros, Trevor M Penning Endocrinology 163 (7), bqac068-, 2022-05-13

...We also found that once 11K-T is formed, it is inactivated to 11β-hydroxy-testosterone (11β-OH-T) by 11β-hydroxysteroid dehydrogenase type 1 (HSD11B1)....

DOI PDF PDF 被引用文献2件

Rania Abdel-Latif, Moustafa Fathy, Hend Ali Anwar, Muhammad Naseem, Thomas Dandekar, Eman M. Othman Antioxidants 11 (5), 863-, 2022-04-28

...administration of kinetin with cisplatin significantly restored testicular oxidative stress parameters, corrected the distorted sperm quality parameters and histopathological changes, enhanced levels of serum testosterone...

DOI Web Site 被引用文献1件

Ali AbuMadighem, Sholom Shuchat, Eitan Lunenfeld, Gilad Yossifon, Mahmoud Huleihel Biofabrication 14 (3), 035004-, 2022-04-20

...The responsiveness of the system to the addition of testosterone and retinoic acid to the culture medium during the experiment was also investigated....

DOI Web Site Web Site 被引用文献1件

Dani Permana, Ksenia Niesel, Mark James Ford, Hirofumi Ichinose ACS Omega 7 (16), 13932-13941, 2022-04-18

DOI Web Site 被引用文献1件

Soejima, Yoshiaki, Otsuka, Yuki, Tokumasu, Kazuki, Nakano, Yasuhiro, Harada, Ko, Nakamoto, Kenta, Sunada, Naruhiko, Sakurada, Yasue, Hasegawa, Kou, Hagiya, Hideharu, Ueda, Keigo, Otsuka, Fumio Medicina-Lithuania 58 (4), 536-, 2022-04-13

...Examination revealed a high Aging Male's Symptoms (AMS) score of 44 and low free testosterone (FT) level of 5.5 pg/mL, which meet the Japanese criteria of late-onset hypogonadism (LOH) syndrome....

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Yoshiaki Soejima, Yuki Otsuka, Kazuki Tokumasu, Yasuhiro Nakano, Ko Harada, Kenta Nakamoto, Naruhiko Sunada, Yasue Sakurada, Kou Hasegawa, Hideharu Hagiya, Keigo Ueda, Fumio Otsuka Medicina 58 (4), 536-, 2022-04-13

...Examination revealed a high Aging Male’s Symptoms (AMS) score of 44 and low free testosterone (FT) level of 5.5 pg/mL, which meet the Japanese criteria of late-onset hypogonadism (LOH) syndrome....

DOI Web Site 被引用文献4件 参考文献36件

T. Durá-Travé, F. Gallinas-Victoriano Journal of Endocrinological Investigation 45 (8), 1577-1585, 2022-04-12

...and free testosterone)....

DOI PDF Web Site 被引用文献1件

Marina Vabistsevits, George Davey Smith, Eleanor Sanderson, Tom G. Richardson, Bethan Lloyd-Lewis, Rebecca C. Richmond Communications Biology 5 (1), 337-, 2022-04-08

...Our results indicate that, while most of the hypothesised mediators are affected by childhood adiposity, only IGF-1 (OR: 1.08 [1.03: 1.15]), testosterone (total/free/bioavailable ~ OR: 1.12 [1.05: 1.20...

DOI PDF Web Site 被引用文献1件

Ghazale Tefagh, Moloud Payab, Mostafa Qorbani, Farshad Sharifi, Yasaman Sharifi, Mahbubeh Sadat Ebrahimnegad Shirvani, Farzad Pourghazi, Rasha Atlasi, Zhaleh Shadman, Nafiseh Rezaei, Erfan Mohammadi-Vajari, Bagher Larijani, Mahbube Ebrahimpur Scientific Reports 12 (1), 2022-04-06

...Furthermore, while Vitamin E supplementation decreases LH and testosterone concentrations, it increases FSH and progestrone concentrations....

DOI PDF Web Site 被引用文献1件

Kazutoshi Fujita, Makoto Matsushita, Eri Banno, Marco A De Velasco, Koji Hatano, Norio Nonomura, Hirotsugu Uemura International Journal of Urology 29 (8), 793-798, 2022-04-06

...Additionally, the gut microbiota can serve as a source of testosterone, which affects prostate cancer progression....

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Yiting Xu, Weijie Cao, Yun Shen, Junling Tang, Yufei Wang, Xiaojing Ma, Yuqian Bao BMC Endocrine Disorders 22 (1), 2022-04-05

...Serum estradiol (E<jats:sub>2</jats:sub>), total testosterone (TT), and sex hormone binding globulin (SHBG) were measured by chemiluminescent microparticle immunoassays....

DOI PDF Web Site 被引用文献1件

Kojima Misaki, Degawa Masakuni Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 45 (4), 508-516, 2022-04-01

...OCT1 and renal OAT1, were primarily due to the difference in serum testosterone concentration....

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Yamamoto, Yukichika, Otsuka, Yuki, Sunada, Naruhiko, Tokumasu, Kazuki, Nakano, Yasuhiro, Honda, Hiroyuki, Sakurada, Yasue, Hagiya, Hideharu, Hanayama, Yoshihisa, Otsuka, Fumio Journal Of Clinical Medicine 11 (7), 1955-, 2022-03-31

...mimicking myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is the most common symptom in long COVID patients, a retrospective analysis was performed for 39 male patients in whom serum free testosterone...

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Yukichika Yamamoto, Yuki Otsuka, Naruhiko Sunada, Kazuki Tokumasu, Yasuhiro Nakano, Hiroyuki Honda, Yasue Sakurada, Hideharu Hagiya, Yoshihisa Hanayama, Fumio Otsuka Journal of Clinical Medicine 11 (7), 1955-, 2022-03-31

...mimicking myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is the most common symptom in long COVID patients, a retrospective analysis was performed for 39 male patients in whom serum free testosterone...

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Emily R McMullen‐Tabry, Andrew P Sciallis, Stephanie L Skala Histopathology 80 (6), 946-953, 2022-03-22

...Cervical transitional cell metaplasia and superficial clusters of small basophilic cells have been described in the context of gender‐affirming testosterone therapy; these findings may be misdiagnosed...

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Akira Takamata, Yuri Nishimura, Ayano Oka, Mayuna Nagata, Natsumi Kosugi, Sayaka Eguchi, Hiroko Negishi, Keiko Morimoto Nutrients 14 (6), 1235-, 2022-03-15

...Food intake induced by glucoprivation was greater in the ORX group than the Sham group, and the glucoprivation-induced food intake was inversely correlated with plasma testosterone concentration....

DOI Web Site 参考文献41件

Anya E Taylor, Meredith A Ware, Emily Breslow, Laura Pyle, Cameron Severn, Kristen J Nadeau, Christine L Chan, Megan M Kelsey, Melanie Cree-Green Journal of the Endocrine Society 6 (7), 2022-03-09

...Testosterone better predicted PCOS status compared to 11-oxyandrogens (receiver operating characteristic curve analysis: 11-OHA4 area under the curve [AUC] = 0.620, 11-OHT AUC = 0.638; testosterone AUC...

DOI PDF PDF 被引用文献1件

Shlomit Jessel, Sarah A. Weiss, Matthew Austin, Amit Mahajan, Katrina Etts, Lin Zhang, Lilach Aizenbud, Ana Luisa Perdigoto, Michael Hurwitz, Mario Sznol, Kevan C. Herold, Harriet M. Kluger Frontiers in Oncology 12 836859-, 2022-03-08

...In select cases, there was evidence of spontaneous rebound in free testosterone levels after an initial decline....

DOI Web Site 被引用文献2件

Marcelo Rodrigues Dos Santos, Thomas W. Storer Endocrinology and Metabolism Clinics of North America 51 (1), 187-204, 2022-03

DOI Web Site Web Site 被引用文献1件

Mustafa Sait Gonen, Annamaria De Bellis, Emre Durcan, Giuseppe Bellastella, Paolo Cirillo, Lorenzo Scappaticcio, Miriam Longo, Basak Ecem Bircan, Serdar Sahin, Cem Sulu, Hande Mefkure Ozkaya, Dildar Konukoglu, Fatma Ferda Kartufan, Fahrettin Kelestimur Hormone and Metabolic Research 54 (03), 153-161, 2022-03

...Patients with COVID-19 had lower free T3, IGF-1, and total testosterone levels, and higher cortisol and prolactin levels when compared with controls....

DOI PDF 被引用文献3件

Can Li, Zhanhong Ye, Anna Jin Xia Zhang, Jasper Fuk Woo Chan, Wenchen Song, Feifei Liu, Yanxia Chen, Mike Yat Wah Kwan, Andrew Chak Yiu Lee, Yan Zhao, Bosco Ho Yin Wong, Cyril Chik Yan Yip, Jian Piao Cai, David Christopher Lung, Siddharth Sridhar, Dongyan Jin, Hin Chu, Kelvin Kai Wang To, Kwok Yung Yuen Clinical Infectious Diseases 75 (1), e974-e990, 2022-02-18

...<jats:title>Results</jats:title> <jats:p>Besides self-limiting respiratory tract infection, intranasal SARS-CoV-2 challenge caused acute decrease in sperm count, serum testosterone...

DOI PDF PDF 被引用文献1件

Sawako Yamauchi, Kousuke Yamamoto, Kazushige Ogawa Biomedicines 10 (2), 487-, 2022-02-18

...Based on previous studies revealing inhibition of testosterone production by P4, we propose that local feedback machinery between Leydig cells and adjacent interstitial Mø regulates testosterone production...

DOI Web Site 被引用文献2件

Linda H Lidborg, Catharine Penelope Cross, Lynda G Boothroyd eLife 11 e65031-, 2022-02-18

...<jats:p>Humans are sexually dimorphic: men and women differ in body build and composition, craniofacial structure, and voice pitch, likely mediated in part by developmental testosterone....

DOI PDF Web Site ほか1件 被引用文献1件

Yasuko Fujisawa, Hiroyuki Ono, Alu Konno, Ikuko Yao, Hiroaki Itoh, Takashi Baba, Kenichirou Morohashi, Yuko Katoh-Fukui, Mami Miyado, Maki Fukami, Tsutomu Ogata Journal of the Endocrine Society 6 (4), 2022-02-15

...deprivation and oxidative stress-evoked apoptotic activation, imply that reduced fetal testosterone production is the primary underlying factor for the development of TDS in intrauterine hyponutrition...

DOI PDF PDF 参考文献63件

Yuta Sekine, Norikazu Hirose Pediatric Exercise Science 34 (1), 28-35, 2022-02-01

...In the collegiate and post-PHV groups, the testosterone-to-cortisol ratio increased post and at 15 minutes after exercise (<jats:italic>P</jats:italic> < .01)....

DOI XML XML 参考文献40件

Eto Eriko, Tani Kazumasa, Maki Jota, Hayata Kei, Masuyama Hisashi Acta Medica Okayama 76 (1), 51-56, 2022-02

...There was no significant difference in values other than QUICKI and testosterone between the women with and without PCOS....

DOI 機関リポジトリ 医中誌

Yamakawa Sho, Hayashida Kenji Journal of Plastic and Reconstructive Surgery 1 (1), 26-30, 2022-01-27

<p>Scrotal defects requiring reconstruction may occur after trauma, cancer, or infection. To maintain good testicular function, the ideal scrotal temperature should be slightly lower than the …

DOI 機関リポジトリ Web Site ほか1件 参考文献15件

Yonah Krakowsky, Emery Potter, Jason Hallarn, Bern Monari, Hannah Wilcox, Greta Bauer, Jacques Ravel, Jessica L. Prodger Frontiers in Cellular and Infection Microbiology 11 2022-01-21

...This review summarizes what is known of the epithelium and local microbiota of the testosterone-exposed vagina and the neovagina....

DOI Web Site 被引用文献1件

Zhongzhong Chen, Yunping Lei, Richard H. Finnell, Zhixi Su, Yaping Wang, Hua Xie, Fang Chen 2022-01-21

...The following transcriptomic analysis further demonstrated that the mutations in the<jats:italic>DNAH8</jats:italic>and<jats:italic>DNAH17</jats:italic>genes might affect the network regulation of testosterone...

DOI Web Site 被引用文献1件

Alireza Mansouri, Rasoul Kowsar, Mostafa Zakariazadeh, Hassan Hakimi, Akio Miyamoto Scientific Reports 12 (1), 717-, 2022-01-13

...., estradiol, progesterone, testosterone, dexamethasone, hydrocortisone, prednisone and calcitriol) could occupy the active site of the protease and could alter the interaction of spike protein with ACE2...

DOI PDF Web Site 被引用文献1件 参考文献67件

Tugce Apaydin, Bahadır Sahin, Saida Dashdamirova, Ceyda Dincer Yazan, Onur Elbasan, Can Ilgin, Hüseyin Bilgin, Haydar Kamil Cam, Gunel Bahramzada, Aleyna Kucuk, Goncagul Haklar, Hulya Iliksu Gozu Andrology 10 (6), 1038-1046, 2022-01-13

...Our second aim was to detect the relationship between free testosterone levels and disease prognosis and determine the impact of low‐free testosterone on admission to the intensive care unit....

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Hui Tao, Takahiro Mori, Heping Chen, Shuang Lyu, Akihito Nonoyama, Shoukou Lee, Ikuro Abe Nature Communications 13 (1), 95-, 2022-01-10

...Moreover, SptF also hydroxylates steroids, including androsterone, testosterone, and progesterone, with different regiospecificities....

DOI PDF Web Site 被引用文献4件 参考文献67件

Yoshida, Atsuko, Kaji, Takashi, Imaizumi, Junki, Shirakawa, Aya, Suga, Kenichi, Nakagawa, Ryuji, Maeda, Kazuhisa, Irahara, Minoru, Iwasa, Takeshi The Journal of Obstetrics and Gynaecology Research 48 (3), 866-868, 2022-01-06

...He was unaware of his pregnancy, resumed testosterone, and continued treatment until pregnancy was confirmed....

機関リポジトリ 医中誌

Kai Furuya, So Fujibayashi, Tao Wu, Kouhei Takahashi, Shin Takase, Ai Orimoto, Eriko Sugano, Hiroshi Tomita, Sayo Kashiwagi, Tohru Kiyono, Tsuyoshi Ishii, Tomokazu Fukuda BMC Genomic Data 23 (1), 2022-01-04

...Testosterone signaling is mediated by the androgen receptor (AR)....

DOI PDF Web Site 被引用文献1件 参考文献14件

Kenichiro Sakaguchi, Tomoko Suda, Nattapong Ninpetch, Kohei Kawano, Yojiro Yanagawa, Seiji Katagiri, Koji Yoshioka, Masashi Nagano Animal Science Journal 93 (1), 2022-01

...Blood was sampled from 0 to 104 h after the first pFSH administration and plasma pFSH, progesterone, androstenedione, testosterone, and estradiol‐17β concentrations were measured....

DOI Web Site Web Site ほか1件 参考文献25件

Manami Miyashita, Masakatsu Fujinoki Reproductive Medicine and Biology 21 (1), 2022-01

...Sera were obtained to determine testosterone concentrations. Sperm were analyzed by video‐microscopy....

DOI Web Site Web Site ほか1件 被引用文献3件 参考文献39件

Nicolas Sayegh, Umang Swami, Neeraj Agarwal JCO Oncology Practice 18 (1), 45-55, 2022-01

...Relugolix has been recently approved as the first oral gonadotropin-releasing hormone receptor antagonist agent with a superior cardiovascular side-effect profile, and serum testosterone suppression compared...

DOI Web Site 被引用文献2件

Selma F. Witchel, Tom Mazur, Christopher P. Houk, Peter A. Lee Hormone Research in Paediatrics 95 (6), 608-618, 2022

...Testosterone was isolated in 1935, and Alfred Jost showed that both circulating testosterone and diffusible anti-Mullerian hormone were needed for male development....

DOI Web Site 被引用文献1件

Salman Z Bhat, Adrian S Dobs European Endocrinology 18 (2), 133-, 2022

...JATENZO® (oral testosterone undecanoate; Clarus Therapeutics Inc., Northbrook, IL, US) is the first oral formulation of testosterone approved by the US Food and Drug Administration....

DOI 被引用文献1件

Aoki Makiko, Satoshi Suzuki, Ryouma Anzai Neuroergonomics and Cognitive Engineering 2022

...Subsequently, the correlation coefficient between the initial activation and testosterone concentration was calculated....

DOI

Noritoshi Kawate Reproductive Medicine and Biology 21 (1), 2022-01

...INSL3 levels are acutely upregulated by luteinizing hormone (LH), and the increase is smaller than that of testosterone in male ruminants, whereas the acute regulation of INSL3 by LH does not occur in...

DOI Web Site Web Site ほか1件 参考文献109件

Makoto Matsushita, Kazutoshi Fujita, Daisuke Motooka, Koji Hatano, Junya Hata, Mitsuhisa Nishimoto, Eri Banno, Kentaro Takezawa, Shinichiro Fukuhara, Hiroshi Kiuchi, Yue Pan, Toshifumi Takao, Akira Tsujimura, Shinichi Yachida, Shota Nakamura, Wataru Obara, Hirotsugu Uemura, Norio Nonomura The World Journal of Men's Health 40 (3), 517-, 2022

DOI Web Site Web Site 被引用文献1件 参考文献36件

Donbaloğlu Zeynep, Tuhan Hale, Çoban Özge Gizli, Kızılay Deniz Özalp, İsmailoğlu Eren, Önder Arif, Acar Sezer, Bedel Aynur, Çetiner Ebru Barsal, Singin Berna, Erdem Harun, Parlak Mesut Ｃｌｉｎｉｃａｌ　Ｐｅｄｉａｔｒｉｃ　Ｅｎｄｏｃｒｉｎｏｌｏｇｙ 31 (2), 68-76, 2022

...The serum free testosterone (fT) levels were positively correlated with the depression and anxiety scores and negatively correlated with the psychosocial PedsQL scores....

DOI Web Site 医中誌 参考文献39件

WEI Yu-Syuan, LIN Wan-Zhen, WANG Tse-En, LEE Wei-Yun, LI Sheng-Hsiang, LIN Fu-Jung, NIXON Brett, SIPILÄ Petra, TSAI Pei-Shiue Journal of Reproduction and Development 68 (3), 198-208, 2022

...Taken together, our data demonstrated that testosterone and sperm maturation status are key regulators of mouse epididymal QSOX1 protein expression and secretion.</p>...

DOI Web Site PubMed ほか1件 参考文献43件

児玉 美穂, 原 鐵晃, 頼 英美, 兒玉 尚志, 大森 由里子, 秋田 智之, 田中 純子 日本産科婦人科内視鏡学会雑誌 38 (1), 19-25, 2022

...</p><p>　The luteinizing hormone/follicle-stimulating hormone (LH/FSH) ratio, serum anti-Müllerian hormone and testosterone concentrations, antral follicle counts, and ovarian volume were significantly...

DOI Web Site 医中誌 参考文献19件

Ueta Yukiko, Aso Keiko, Haga Youichi, Takahashi Hiroyuki, Satoh Mari Ｃｌｉｎｉｃａｌ　Ｐｅｄｉａｔｒｉｃ　Ｅｎｄｏｃｒｉｎｏｌｏｇｙ 31 (3), 159-162, 2022

...Since his serum LH, FSH, and testosterone levels were low (< 0.3 mIU/mL, 0.08 mIU/mL, and < 0.03 ng/mL, respectively), Kallmann syndrome/normosmic hypogonadotropic hypogonadism was suspected...

DOI Web Site 医中誌 参考文献23件

Kim Yoon-Jae, Park Ji-Eun, Chung Jin-Yong, Kim Ji Young, Lee Seung Gee, Lee Seung-Jin, Yu Wook-Joon, Kim Hye Young, Kim Hyeon Jun, Koh Hyungjong, Bae Hae-Rahn, Yoo Young Hyun, Kim Jong-Min Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃａｌ　Ｓｃｉｅｎｃｅｓ 47 (8), 317-326, 2022

...<p>Testicular Leydig cells produce testosterone through the participation of steroidogenic proteins....

DOI Web Site Web Site ほか1件 参考文献31件

Cao Weijie, Xu Yiting, Shen Yun, Wang Yufei, Ma Xiaojing, Bao Yuqian Endocrine Journal 69 (8), 1007-1014, 2022

...Serum estradiol (E2), total testosterone (TT), sex hormone-binding globulin (SHBG), FSH, and LH were measured by chemiluminescent microparticle immunoassay....

DOI Web Site PubMed ほか1件 参考文献33件

毛利 惠子, 橋本 千絵, 柴田 翔平, 戸田 和弥, 清水 慶子 霊長類研究　Supplement 38 (0), 65-, 2022

...カラム保存と冷凍保存の尿中cortisol, testosterone, estrone-conjugates, pregnanediol-glucuronideを測定し比較したところ、両者の動態に違いはなかった。また、カラム保存した尿のコルチゾール量は冷凍保存の結果より高濃度であった。...

DOI

Nori Wassan, Harmoosh Shaima K., Abd Al-Badri Hadeel J. The Journal of Medical Investigation 69 (3.4), 191-195, 2022

...HOMA-IR, LDL, testosterone, and LH / FSH were higher in PCOS and strongly correlated with RDW with positive correlations. HDL was elevated and correlated negatively with RDW in PCOS....

DOI 機関リポジトリ Web Site ほか2件 参考文献28件

青野 健太郎, 松本 純一, 松本 太一, 池田 弥恵, 河村 莉奈, 山内 淳史 日本薬理学会年会要旨集 96 (0), 4-B-P-313-, 2022

...We previously showed that testosterone deficiency exacerbated porcine pancreatic elastase (PPE)-induced destruction of the alveolar structure in orchiectomy (ORX) mice, suggesting testosterone may have...

DOI Web Site

Furukawa Satoshi, Tsuji Naho, Hayashi Seigo, Kuroda Yusuke, Kimura Masayuki, Hayakawa Chisato, Takeuchi Kazuya, Sugiyama Akihiko Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃ　Ｐａｔｈｏｌｏｇｙ 35 (1), 37-44, 2022

...<p> We investigated the morphological effects of testosterone on placental development in a rat model of polycystic ovarian syndrome (PCOS)....

DOI Web Site Web Site ほか1件 参考文献30件

大西 克典, 河原 幸江, 岸 由紀, 大西 陽子, 西 昭徳 日本薬理学会年会要旨集 95 (0), 1-P-031-, 2022

...</p><p>In these approaches, only testosterone injections were able to increase the attractiveness of the unattractive male mice....

DOI Web Site

片岡 智哉, 真川 明将, 堀田 祐志, 日比 陽子, 木村 和哲 日本薬理学会年会要旨集 95 (0), 2-O-074-, 2022

...We investigated the effect of testosterone replacement therapy (TRT) on ED by DOX....

DOI Web Site

野末 彰子, 西出 健 日本産科婦人科内視鏡学会雑誌 38 (1), 111-117, 2022

...</p><p>　A PCOS-like condition was diagnosed, based on ovarian pathology and the high testosterone level preoperatively.</p><p>　PCOS without tumors has the risk of causing ovary torsion....

DOI Web Site 参考文献17件

Chen Jing, Minabe Shiori, Munetomo Arisa, Magata Fumie, Sato Marimo, Nakamura Sho, Hirabayashi Masumi, Ishihara Yasuhiro, Yamazaki Takeshi, Uenoyama Yoshihisa, Tsukamura Hiroko, Matsuda Fuko Endocrine Journal 69 (7), 797-807, 2022

...The present study aimed to investigate the role of <i>Kiss1</i>/kisspeptin in generating perinatal plasma LH and the consequent testosterone increase in male rats by comparing the plasma testosterone and...

DOI Web Site PubMed ほか1件 被引用文献2件 参考文献44件

Yoshimura Kai, Yamamoto Masaaki, Inoue Tomoya, Fukuoka Hidenori, Iida Keiji, Ogawa Wataru Endocrine Journal 69 (11), 1335-1342, 2022

<p>Coronavirus disease 2019 (COVID-19) is associated with endocrine disorders, but their long-term clinical course remains unclear. We here report the 15-month clinical course for an individual with …

DOI HANDLE Web Site ほか2件 被引用文献3件 参考文献52件

Nishikawa Mai, Ohara Naoki, Naito Yukiko, Amma Chihiro, Saito Yoshiaki, Tatematsu Kenjiro, Baoyindugurong Jinhua, Miyazawa Daisuke, Hashimoto Yoko, Okuyama Harumi Fundamental Toxicological Sciences 9 (1), 7-16, 2022

...The decreased testosterone and the concomitantly increased aldosterone may play a role in the aggravation by CAN of the genetic diseases (i.e., metabolic syndrome-like complications) in male SHRSP....

DOI Web Site 医中誌 参考文献30件

木口 倫一, 鈴木 堅太郎 日本薬理学会年会要旨集 95 (0), 3-O-103-, 2022

...Moreover, nerve injury-induced mechanical allodynia in female mice was prevented by administration of testosterone propionate, suggesting that androgens might determines sex differences of microglia....

DOI Web Site

Maeyama Takatoshi, Ichikawa Chihiro, Okada Yosuke, Sawada Akihisa, Inoue Masami, Takeuchi Makoto, Soh Hideki, Usui Noriaki, Etani Yuri, Kawai Masanobu Endocrine Journal 69 (3), 313-318, 2022

...Surgical removal of the tumor promptly normalized serum β-hCG and testosterone levels....

DOI Web Site PubMed ほか1件 参考文献9件

Urhan Emre, Karaca Zuleyha, Unuvar Gamze Kalin, Gundogan Kursat, Unluhizarci Kursad Endocrine Journal 69 (6), 649-658, 2022

...Mean total testosterone values were lower in male patients when compared to male controls; however, the difference was not significant....

DOI Web Site PubMed ほか1件 被引用文献3件 参考文献52件

宮宗 秀伸, 吉岡 広陽, 高野 海哉, 永堀 健太, 李 忠連, 倉升 三幸, 小川 夕輝, 松野 義晴, 伊藤 正裕 日本毒性学会学術年会 49.1 (0), S37-2-, 2022

<p>発達早期の環境要因は、雄性生殖器系に健康影響を引き起こすことが知られている。エストロゲンやアンドロゲンを含む性ホルモンの投与や内分泌かく乱物質を始めとする化学物質への曝露は児の雄性生殖器系の正常な発達に必要な各種ホルモンの血中レベルを変動させ、結果として精巣や精子形成に影響を生じるとされる。ここで、近年我々は、雄性生殖器系に健康影響を引き起こす発達早期の環境要因として、ストレスホルモンに着…

DOI

Aoki Masako, Uehara Shuichiro, Nishimaki Haruna, Aoki Ryoji, Kayama Kazunori, Nagano Nobuhiko, Urakami Tatsuhiko, Morioka Ichiro Endocrine Journal 69 (8), 919-926, 2022

...At birth, she also presented with clitoromegaly and elevated serum levels of 17α-hydroxyprogesterone, dehydroepiandrosterone, and testosterone at birth and experienced hyper-insulinemic hypoglycemia, which...

DOI Web Site PubMed ほか1件 参考文献22件

Akehi Yuko, Tanabe Makito, Yano Hiromi, Takashi Yuichi, Kawanami Daiji, Nomiyama Takashi, Yanase Toshihiko Endocrine Journal 69 (11), 1303-1312, 2022

...In the Japanese guidelines, a free testosterone (FT) <8.5 pg/mL is recommended for testosterone treatment....

DOI Web Site PubMed ほか1件 参考文献21件

大塚 雄一郎, 根本 俊光, 晝間 清, 山崎 一樹, 花澤 豊行 日本鼻科学会会誌 61 (4), 663-669, 2022

<p>Kallmann症候群は低ゴナドトロピン性の性腺機能低下症を主症候に，先天性嗅覚障害などを副症候とするまれな先天性疾患である。症例は56歳男性。大腿骨骨折を契機に著しい骨粗鬆症が認められた。女性様顔貌や高い音声から性腺機能低下症を疑われた。変声期がなく思春期を経過，女性化乳房，陰毛が少ない，腋毛がないこと，さらに陰茎と睾丸の発育抑制が認められた。先天性嗅覚障害で静脈性嗅覚検査は無反応であっ…

DOI Web Site 医中誌 参考文献4件

片岡 智哉, 深本 絢子, 堀田 祐志, 真川 明将, 前田 康博, 日比 陽子, 木村 和哲 日本薬理学会年会要旨集 96 (0), 2-B-O01-2-, 2022

...with 6.25, 25 or 100 mg/kg testosterone per week....

DOI Web Site

木口 倫一, 雑賀 史浩, 波多野 裕, 日野 信次朗, 鈴木 堅太郎 日本薬理学会年会要旨集 96 (0), 2-B-O04-3-, 2022

...Gonadectomy (GDX) decreased in serum testosterone concentration and mechanical pain threshold in male mice....

DOI Web Site

岩鶴 果奈, 坂本 多穗, 竹下 舜也, 山下 ほのか, 黒川 洵子 日本薬理学会年会要旨集 96 (0), YIA04-4-, 2022

...In vitro analysis using C2C12 myotubes revealed that estradiol-treatment but not testosterone-treatment enhance mRNA expressions of these genes....

DOI Web Site

上西 正子, 望月 泰秀, 竹内 陽史郎, 田村 仁香, 堀家 由貴, 藤田 淳子, 高岡 理恵, 山崎 正之, 田中 早津紀, 志手 淳也 超音波医学 49 (1), 51-56, 2022

<p>症例は40歳代男性，主訴は労作時呼吸苦である．元来筋力トレーニングが趣味であり，6年前から筋力増強目的にAnabolic androgenic steroid（AAS）の一種であるデカン酸ナンドロロンを個人輸入し，使用していた．某年11月頃，高血圧と心拡大のため当院紹介．初診時の経胸壁心臓超音波検査では，左室腔拡大と全周性の左室壁肥厚，左室収縮能および拡張能の低下を認めた．血液生化学検査で…

DOI Web Site 医中誌 参考文献7件

KOHYAMA Kaoru, INOSHIMA Yasuo, KIYOTA Masashi Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 84 (1), 171-180, 2022

...Small increases in the serum testosterone signaled puberty in males aged 3 and 4 years....

DOI Web Site PubMed ほか1件 参考文献44件

香川 匠 日本毒性学会学術年会 49.1 (0), O-28-, 2022

<p>【背景・目的】</p><p>環境中に存在する化学物質の曝露による内分泌系や生殖機能への影響が懸念されている。食品や医療機器の滅菌に使用されるエチレンオキシドをはじめとして、動物試験において生殖機能及び性ホルモンに与える影響が懸念されているにも関わらず、ヒトの日常曝露における影響評価が十分ではない化学物質が多く存在する。本研究では汎用される化学物質のヒト血中レベルと性ホルモンとの関連性を調査…

DOI

WIMALARATHNE Hewage Dilhan Anuradha, WAKO Hiroaki, KAWATE Noritoshi Journal of Reproduction and Development 68 (5), 324-329, 2022

...Follicular cysts may retain the production of INSL3 during their formation but tend to lose the capacity for testosterone secretion....

DOI Web Site PubMed ほか1件 被引用文献1件 参考文献52件

Ueda Yuko, Suzuki Kentaro, Kajimoto Mizuki, Fujimoto Kota, Mahendroo Mala, Ema Masatsugu, Yamada Gen, Hara Isao Experimental Animals 71 (4), 451-459, 2022

...The 5-α reductase type 2 encoded by the SRD5A2 gene has been suggested to be a crucial enzyme for male sexual differentiation, as it converts testosterone (T) into DHT in the local urogenital organs....

DOI Web Site PubMed ほか1件 被引用文献1件 参考文献51件

SHINYA So, YOHANNES Yared Beyene, IKENAKA Yoshinori, NAKAYAMA Shouta MM, ISHIZUKA Mayumi, FUJITA Shoichi Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 84 (12), 1665-1672, 2022

...To better understand the properties of CYP-dependent metabolism, <i>in vitro</i> metabolic activity studies were performed using ethoxyresorufin, pentoxyresorufin and testosterone as...

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Mima Yasuyuki, Sugishita Yodo, Meng Lingbo, Nishimura Sandy, Suzuki-Takahashi Yuki, Hashiba Moka, Ideta Rio, Matsuyama Natsumi, Furuyama Sayako, Nakajima Mariko, Iwahata Hideyuki, Takae Seido, Horage-Okutsu Yuki, Suzuki Nao Journal of St. Marianna University 13 (2), 137-147, 2022

...</p><p><b>Results</b>: Compared to the control group, the levels of E2 were significantly suppressed while the testosterone and AMH levels increased in the AI group....

DOI Web Site 医中誌 参考文献28件

Laura D. Locati, Stefano Cavalieri, Cristiana Bergamini, Carlo Resteghini, Elena Colombo, Giuseppina Calareso, Luigi Mariani, Pasquale Quattrone, Salvatore Alfieri, Paolo Bossi, Francesca Platini, Iolanda Capone, Lisa Licitra Journal of Clinical Oncology 39 (36), 4061-4068, 2021-12-20

...eligible when the following criteria were met: histologic diagnosis of AR-overexpressing SGC, measurable disease according to RECIST 1.1, clinical and/or radiologic progression on ADT, suppressed serum testosterone...

DOI Web Site 被引用文献4件

Fabio Vescini, Iacopo Chiodini, Alberto Falchetti, Andrea Palermo, Antonio Stefano Salcuni, Stefania Bonadonna, Vincenzo De Geronimo, Roberto Cesareo, Luca Giovanelli, Martina Brigo, Francesco Bertoldo, Alfredo Scillitani, Luigi Gennari International Journal of Molecular Sciences 22 (24), 13640-, 2021-12-20

...Hypogonadal patients may be treated with testosterone replacement therapy....

DOI Web Site 被引用文献1件

James M Smoliga, Lucas K Fogaca, Jessica S Siplon, Abigail A Goldburt, Franziska Jakobs BMJ 375 e067849-, 2021-12-15

...or inappropriate reporting can lead to claims of statistically significant (yet, biologically meaningless) biomarker associations, using as a model the relation between a common surrogate of prenatal testosterone...

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Leticia R. de Oliveira, Carlos A. Longui, Guilherme Guaragna-Filho, José L. da Costa, Rafael Lanaro, Maria I. Chiamolera, Maricilda P. de Mello, André M. Morcillo, Andrea T. Maciel-Guerra, Gil Guerra-Junior Sexual Development 16 (4), 266-269, 2021-12-14

...This study aimed to determine a testosterone (T) cutoff level that indicates an adequate testicular function using LC-MS/MS after stimulation with recombinant human chorionic gonadotropin (rhCG) in a single...

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Selinay Başak Erdemli‐Köse, Anıl Yirün, Aylin Balci‐Özyurt, Pınar Erkekoğlu Journal of Applied Toxicology 42 (6), 981-994, 2021-12-07

...thimerosal (TT): 1‐μM testosterone + 0.75‐μM estradiol + 1.15‐μM thimerosal, high estradiol/low testosterone + thimerosal (ET): 0.1‐μM testosterone + 7.5‐μM estradiol + 1.15‐μM thimerosal, high testosterone...

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Cristina Aguirre-Portolés, Riley Payne, Aspen Trautz, J. Kevin Foskett, Christopher A. Natale, John T. Seykora, Todd W. Ridky Cancer Research 81 (23), 5991-6003, 2021-12-01

...This testosterone activity required an influx of zinc, activation of MAPK, and nuclear translocation of YAP....

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Takeshi Akiyoshi, Rina Naitou, Ayuko Imaoka, Mitsue Miyazaki, F. Peter Guengerich, Katsunori Nakamura, Koujiro Yamamoto, Hisakazu Ohtani Int. Journal of Clinical Pharmacology and Therapeutics 59 (12), 745-752, 2021-12-01

DOI

Iwata Takehiro, Maruyama Yuki, Kawada Tatsushi, Sadahira Takuya, Katayama Satoshi, Takamoto Atsushi, Sako Tomoko, Wada Koichiro, Edamura Kohei, Kobayashi Yasuyuki, Araki Motoo, Watanabe Masami, Watanabe Toyohiko, Nasu Yasutomo Acta Medica Okayama 75 (6), 705-711, 2021-12

...In the multivariate analysis, no actor was associated with testosterone recovery....

DOI 機関リポジトリ 医中誌

Meganne N. Ferrel, Sentia Iriana, I. Raymond Thomason, Christy L. Ma, Katsiaryna Tsarova, Brent D. Wilson, Stephen H. McKellar, John J. Ryan BMC Cardiovascular Disorders 21 (1), 2021-11-22

...The patient also reported a 20-year history of performance enhancing drugs including testosterone....

DOI PDF Web Site 被引用文献1件

João Paulo L. F. Guilherme, Ekaterina A. Semenova, Oleg V. Borisov, Andrey K. Larin, Ethan Moreland, Edward V. Generozov, Ildus I. Ahmetov European Journal of Applied Physiology 122 (2), 415-423, 2021-11-18

...Based on these five SNPs, the number of testosterone-increasing alleles was positively associated with testosterone levels in male athletes (<jats:italic>P</jats:italic> = 0.048) and greater strength performance...

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Kristian Leisegang, Shubhadeep Roychoudhury, Petr Slama, Renata Finelli Antioxidants 10 (11), 1834-, 2021-11-18

...Male hypogonadism, characterized by reduced testosterone, is commonly seen in ageing males, and has a complex relationship as a risk factor and a comorbidity in age-related noncommunicable chronic diseases...

DOI Web Site 被引用文献1件

Suzanne H. Austin, Jesse S. Krause, Rechelle Viernes, Victoria S. Farrar, April M. Booth, Rayna M. Harris, Frédéric Angelier, Candice Lee, Annie Bond, John C. Wingfield, Matthew M. MacManes, Rebecca M. Calisi Frontiers in Endocrinology 12 2021-11-11

...Males generally responded quickly following nest loss by increasing circulating testosterone, but this response was muted when nest loss occurred early in reproduction....

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Tomoko Yoshida, Kenji Matsumoto, Mami Miyado, Yoshimichi Miyashiro, Haruhiko Sago, Reiko Horikawa, Maki Fukami European Journal of Endocrinology 185 (5), K7-K11, 2021-11-01

...<jats:sec> <jats:title>Introduction</jats:title> <jats:p>The two major androgens in humans are testosterone (T) and dihydrotestosterone (DHT)....

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Hui Li, Daniel J Spade Reproduction 162 (5), F147-F167, 2021-11-01

...Phthalates disrupt the seminiferous cord formation and maturation, Sertoli cell function, biosynthesis of testosterone in Leydig cells, and impair germ cell survival and development, producing characteristic...

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