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Keiji Murayama, Hikari Okita, Hiroyuki Asanuma Bulletin of the Chemical Society of Japan 96 (10), 1179-1187, 2023-10

<jats:title>Abstract</jats:title> <jats:p>In this account, we discuss applications of artificial nucleic acids, acyclic threoninol nucleic acid (aTNA) and serinol nucleic acid (SNA). …

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Zujur, Denise, Al-Akashi, Ziadoon, 中村, アンナ, 趙, 成珠, Takahashi, Kazuma, 有富, 静, Theoputra, William, 上谷, 大介, 中山, 功一, 池谷, 真 Frontiers in Cell and Developmental Biology 11 2023-05-10

...stepwise differentiation method to generate matrix-rich cartilage spheroids from induced pluripotent stem cell-derived mesenchymal stem/stromal cells (iMSCs) via the induction of neural crest cells under xeno-free...

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Iwasaki Mio Journal of Proteome Data and Methods 5 (0), 12-, 2023

...<p>Xeno-free culture system is useful for research of regenerative medicine, but variability in passaging steps sometimes affects reproducibility....

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Tsuyoshi Takamura, Hiroshi Nagashima, Hitomi Matsunari, Shuichiro Yamanaka, Yatsumu Saito, Yoshitaka Kinoshita, Toshinari Fujimoto, Kei Matsumoto, Kazuaki Nakano, Hirotaka James Okano, Eiji Kobayashi, Takashi Yokoo Journal of Clinical Medicine 11 (23), 7237-, 2022-12-06

...xeno-metanephroi and renal progenitor cells should be established....

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Toshiro Iwagawa, Hiroki Masumoto, Hitoshi Tabuchi, Kenzaburo Tani, Bruce R. Conklin, Sumiko Watanabe The Journal of Gene Medicine 25 (2), 2022-12-04

<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Exon‐skipping is a powerful genetic tool, especially when delivering genes using an AAV‐mediated full‐length …

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高田, 圭, 中谷, 良子, 森部, 江美子, 山崎-藤垣, 静香, 藤井, 麻衣, 古田, 昌代, 末盛, 博文, 川瀬, 栄八郎 Regenerative Therapy 21 553-559, 2022-12

...[Methods] To establish clinical-grade hESC lines, we used xeno-free chemically defined medium StemFit AK03N with the LM-E8 fragments instead of feeder cells....

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Fujisawa, Yuki, Ming, Lu, Yamada, Daisuke, Takao, Tomoka, Takarada, Takeshi STEM Cell Research & Therapy 13 (1), 515-, 2022-11-12

...Here, we established an hPSC-derived MKX-tdTomato reporter cell line and tested the induction ratio of MKX-tdTomato(+) cells using our stepwise/xeno-free differentiation protocol....

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Yan-Da Li, Yu-Bo Zhang, Karol Szawaryn, Di-Ying Huang, Chen-Yang Cai Arthropod Systematics & Phylogeny 80 411-422, 2022-08-18

...Based on its distinctive morphology and the phylogenetic results, <jats:italic>Xenostanus</jats:italic> is placed in the tribe Xenostanini Li, Szawaryn & Cai <jats:bold>trib. nov....

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Alexandra Kammen, Jonathon Cavaleri, Jordan Lam, Adam C. Frank, Xenos Mason, Wooseong Choi, Marisa Penn, Kaevon Brasfield, Barbara Van Noppen, Stuart B. Murray, Darrin Jason Lee Frontiers in Neurology 13 2022-08-09

<jats:p>Early research into neural correlates of obsessive compulsive disorder (OCD) has focused on individual components, several network-based models have emerged from more recent data on …

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Ying Hua, Kenji Yoshimochi, Junjun Li, Kazuhiro Takekita, Motoshi Shimotsuma, Lingjun Li, Xiang Qu, Jingbo Zhang, Yoshiki Sawa, Li Liu, Shigeru Miyagawa Stem Cell Research & Therapy 13 (1), 223-, 2022-06-03

...To satisfy the sizable requirement for clinical applications of hiPSCs, large-scale, expansion-oriented, xeno-free, and cost-effective media are critical....

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Yoko Masuzawa, Manabu Kitazawa Materials 15 (10), 3687-, 2022-05-20

...A major challenge to the growth and proliferation of iPSCs is the maintenance of their undifferentiated status in xeno- and feeder-free conditions....

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Shuji Miyagawa, Akira Maeda, Chiyoshi Toyama, Shuhei Kogata, Chizu Okamatsu, Riho Yamamoto, Kazunori Masahata, Masafumi Kamiyama, Hiroshi Eguchi, Masahito Watanabe, Hiroshi Nagashima, Masahito Ikawa, Katsuyoshi Matsunami, Hiroomi Okuyama Frontiers in Immunology 13 2022-04-14

...The complement system therefore is still an important recognition and effector mechanism in xeno-rejection....

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高橋, 和利, 大久保, 周子, 中村, 美千子, 岩崎, 未央, 川原, 優香, 田畑, 剛, 宮本, 洋佑, Woltjen, Knut, 山中, 伸弥 Cell Reports Methods 2 (2), 2022-02-28

...Xeno-free culture systems have expanded the clinical and industrial application of human pluripotent stem cells (PSCs)....

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Shuichiro Yamanaka Clinical and Experimental Nephrology 26 (6), 491-500, 2022-02-09

...Generating nephrons from syngeneic stem cells to increase self-cell ratio in xeno-tissues can reduce the risk of xeno-rejection....

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Dimitrios Xenos, Pavlos Texakalidis, Constantine L. Karras, Nikhil K. Murthy, Marinos Kontzialis, Dennis J. Rivet, John Reavey-Cantwell World Neurosurgery 158 258-267.e1, 2022-02

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上谷, 大介, 竹中, 菜々, 本池, 総太, 加治屋, 幹人, 赤星, 哲平, 趙, 成珠, 柴田, 光章, 千田, 将, 豊岡, やよい, 櫻井, 英俊, 栗原, 英見, 池谷, 真 npj Regenerative Medicine 7 17-, 2022

...We modified a previous MSC induction method to work under xeno-free conditions....

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松本, 太郎, 副島, 一孝, 樫村, 勉, 李, 予昕, 風間, 智彦, 萩倉, 一博, 山元, 智衣, 長岡, 悠紀 研究紀要 10 34-39, 2022

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LF Alegría-Acevedo, MF Gutiérrez, J Perdigão, A Núñez, L Méndez-Bauer, A Dávila-Sanchez, A Reis, AD Loguercio Operative Dentistry 47 (1), 107-120, 2022-01-01

...Universal [AMB]; 4) Clearfil Universal Bond [CFU]; 5) Futurabond U [FBU]; 6) One Coat 7 Universal [OCU]; 7) Peak Universal Bond [PUB]; 8) Prime&Bond Elect [PBE]; 9) Scotchbond Universal Adhesive [SBU]; 10) Xeno...

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Hiroyuki Asanuma, Yukiko Kamiya, Hiromu Kashida, Keiji Murayama Chemical Communications 58 (25), 3993-4004, 2022

<jats:p>We review the chemical structures of XNAs with non-ribose scaffolds, their hybridization abilities, and their unique behaviors with a particular focus on the acyclic XNAs.</jats:p>

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池本 哲也, 島田 光生, 齋藤 裕, 寺奥 大貴, 山田 眞一郎, 森根 裕二 移植 57 (Supplement), s162_2-s162_2, 2022

...</p><p>【方法】ヒト脂肪由来幹細胞を用いて我々の開発したInsulin-producing cell(IPC)分化誘導法を新規3次元培養法(RCP peace)・xeno-antigen freeの方法へ改変し、in vitro/ in vivo assayを行った。良好な本研究の結果を基にAMEDの研究にapplyした。　...

DOI

Xu, Huaigeng, 北, 悠人, Bang, Uikyu, Gee, Peter, 堀田, 秋津 STAR Protocols 2 (4), 100965-, 2021-12-17

...Here, we describe the optimized protocol to introduce a single nucleotide change or a loxP site insertion in feeder-free, xeno-free iPSCs by utilizing MaxCyte and 4D-Nucleofector electroporators....

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Susumu Horikoshi, Mikihito Kajiya, Souta Motoike, Mai Yoshino, Shin Morimoto, Hiroki Yoshii, Tomoya Ogawa, Hisakatsu Sone, Tomoyuki Iwata, Kazuhisa Ouhara, Shinji Matsuda, Noriyoshi Mizuno, Hidemi Kurihara Biomedicines 9 (10), 1408-, 2021-10-07

...Human bone marrow-derived MSCs were cultured with xeno-free/serum-free (XF) growth medium....

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Syeda M. Bakht, Manuel Gomez‐Florit, Tara Lamers, Rui L. Reis, Rui M. A. Domingues, Manuela E. Gomes Advanced Functional Materials 31 (46), 2021-08-11

...In summary, this xeno‐free nanoscale CNC fibrillar matrix allows the biofabrication of hierarchical living constructs, opening new opportunities not only for developing physiologically relevant 3D in vitro...

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Paulina Hennig, Gabriele Fenini, Michela Di Filippo, Tugay Karakaya, Hans-Dietmar Beer Biomedicines 9 (7), 707-, 2021-06-22

...Via binding of ubiquitin chains, p62 acts in an anti-inflammatory manner as an adaptor for the auto-, xeno-, and mitophagy-dependent degradation of proteins, pathogens, and mitochondria....

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Hiroki Takeuchi, Mikiko Nishioka, Tadashi Maezawa, Yuko Kitano, Kento Terada-Yoshikawa, Ryota Tachibana, Manabu Kato, Suong-hyu Hyon, Yuki Gen, Kayo Tanaka, Kuniaki Toriyabe, Masafumi Nii, Eiji Kondo, Tomoaki Ikeda Cells 10 (6), 1435-, 2021-06-08

...Therefore, the development of xeno-free human sperm cryopreservative reagents that could overcome the aforementioned problems is warranted....

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Keiji Murayama, Hiroyuki Asanuma ChemBioChem 22 (15), 2507-2515, 2021-06-02

...<jats:title>Abstract</jats:title><jats:p>Xeno nucleic acids (XNAs) are analogues of DNA and RNA that have a non‐ribose artificial scaffold....

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Kathleen Van Beylen, Ioannis Papantoniou, Jean-Marie Aerts Frontiers in Bioengineering and Biotechnology 9 624890-, 2021-05-24

...The results showed that expanding human periosteum-derived progenitor cells in spinner flasks using xeno-free medium and Star-Plus microcarriers, does not affect the potency, identity or viability of the...

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Yukina Kuwahara, Karin Yoshizaki, Hidetaka Nishida, Hiroaki Kamishina, Sadatoshi Maeda, Katsura Takano, Naoki Fujita, Ryohei Nishimura, Jun-ichiro Jo, Yasuhiko Tabata, Hideo Akiyoshi Frontiers in Veterinary Science 8 2021-04-28

...Manufacture of MSC-EVs for clinical application mandates removal of the xeno-proteins, including fetal bovine serum....

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Naritaka Tamaoki, Stefan Siebert, Takuya Maeda, Ngoc-Han Ha, Meghan L. Good, Yin Huang, Suman Kumar Vodnala, Juan J. Haro-Mora, Naoya Uchida, John F. Tisdale, Colin L. Sweeney, Uimook Choi, Julie Brault, Sherry Koontz, Harry L. Malech, Yasuhiro Yamazaki, Risa Isonaka, David S. Goldstein, Masaki Kimura, Takanori Takebe, Jizhong Zou, David F. Stroncek, Pamela G. Robey, Michael J. Kruhlak, Nicholas P. Restifo, Raul Vizcardo 2021-04-26

...Notably, our organoid system can be performed in a scalable, autologous, and xeno-free condition, thereby providing an important model of human definitive yolk sac development and allows for efficient...

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吉松, 誠芳, 大西, 弘恵, 趙, 成珠, 林, 泰之, 桑田, 文彦, 椛, 慎治, 奧山, 英晃, 河合, 良隆, 樋渡, 直, 岸本, 曜, Sakamoto, Tatsunori, 池谷, 真, 大森, 孝一 Stem Cell Research 52 102233-, 2021-04

...For the relevance to prospective future clinical application, induction was conducted under xeno-free/serum-free conditions....

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Laura Beani, Romano Dallai, Federico Cappa, Fabio Manfredini, Marco Zaccaroni, Maria Cristina Lorenzi, David Mercati Scientific Reports 11 (1), 2021-03-31

...<jats:italic>Polistes dominula</jats:italic> paper wasps infected by the strepsipteran parasite <jats:italic>Xenos vesparum</jats:italic> avoid all colony tasks, cluster on vegetation where parasite dispersal...

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Zihao Chen, Long Hu, Bao-Ting Zhang, Aiping Lu, Yaofeng Wang, Yuanyuan Yu, Ge Zhang International Journal of Molecular Sciences 22 (7), 3605-, 2021-03-30

...<jats:p>Aptamers are short single-stranded DNA, RNA, or synthetic Xeno nucleic acids (XNA) molecules that can interact with corresponding targets with high affinity....

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佐々木, 啓子, 和田, 啓爾, 松岡, 耕二, SASAKI, Yusuke, WADA, Keiji, MATUOKA, Koozi 千葉科学大学紀要 (14) 15-20, 2021-03-28

...Cancer chemoprevention relies on the use of naturally occurring or synthetic chemicals, known as xeno biotics, to suppress carcinogen s, through a mechanism via induction of phase I and phase II drug metabolizing...

機関リポジトリ 医中誌

Keiji Murayama, Hikari Okita, Takumi Kuriki, Hiroyuki Asanuma Nature Communications 12 (1), 804-, 2021-02-05

...<jats:title>Abstract</jats:title><jats:p>Evolution of xeno nucleic acid (XNA) world essentially requires template-directed synthesis of XNA polymers....

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Van T. Hoang, Quynh-Mai Trinh, Dam Thi Minh Phuong, Hue Thi Hong Bui, Le Minh Hang, Nguyen Thi Hong Ngan, Nguyen Thi Tuyet Anh, Phung Yen Nhi, Trinh Thi Hong Nhung, Ha Thi Lien, Tu Dac Nguyen, Liem Nguyen Thanh, Duc M. Hoang Cytotherapy 23 (1), 88-99, 2021-01

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Abe Rei, Yamauchi Kazuyo, Kuniyoshi Kazuki, Suzuki Takane, Matsuura Yusuke, Ohtori Seiji, Takahashi Kazuhisa Journal of Rural Medicine 16 (3), 143-147, 2021

...However, the clinical application of these technologies requires the reduction of xeno-materials....

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BAMBA Kenzo, OZAWA Midori, TAMAI Miho, SHIMBO Emiko, SHINDO Hiromasa, OTA Takuo, AHN Sungho, KOHARA Arihiro, TAGAWA Yoh-ichi Translational and Regulatory Sciences 3 (3), 77-82, 2021

...This xeno-free freezing medium was shown to have the potential for application in the cryopreservation of cells used in regenerative medicine.</p>...

DOI Web Site 参考文献19件

池本 哲也, 齋藤 裕, 宮崎 克己, 沖川 昌平, 寺奥 大貴, 山田 眞一郎, 森根 裕二, 島田 光生 移植 56 (Supplement), s502-s502, 2021

...</p><p>【方法】手術時に破棄される皮下脂肪（徳島大学病院IRB承認3090）からADSCに分離精製後、樹立したxeno-antigen free/2-step/3次元大量培養法でIPCを分化誘導し、cell quality評価・ in vivo解析を行った。...

DOI

絵野沢 伸 Organ Biology 28 (2), 168-169, 2021

DOI

Laura Beani, Marta Mariotti Lippi, Nadia Mulinacci, Fabio Manfredini, Lorenzo Cecchi, Claudia Giuliani, Corrado Tani, Niccolò Meriggi, Duccio Cavalieri, Federico Cappa PLOS ONE 15 (12), e0242486-, 2020-12-16

...<jats:p>Paper wasps (<jats:italic>Polistes dominula</jats:italic>), parasitized by the strepsipteran <jats:italic>Xenos vesparum</jats:italic>, are castrated and desert the colony to gather on plants where...

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Arne Hinrichs, Evamaria O. Riedel, Nikolai Klymiuk, Andreas Blutke, Elisabeth Kemter, Matthias Längin, Maik Dahlhoff, Barbara Keßler, Mayuko Kurome, Valeri Zakhartchenko, Eva‐Maria Jemiller, David Ayares, Martin Bidlingmaier, Florian Flenkenthaler, Martin Hrabĕ de Angelis, Georg J. Arnold, Bruno Reichart, Thomas Fröhlich, Eckhard Wolf Xenotransplantation 28 (2), 2020-11-25

...The intrinsic growth potential of porcine xeno‐organs may impair their long‐term function after orthotopic transplantation in non‐human primate models....

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Yukiko Kamiya, Tadashi Satoh, Atsuji Kodama, Tatsuya Suzuki, Keiji Murayama, Hiromu Kashida, Susumu Uchiyama, Koichi Kato, Hiroyuki Asanuma Communications Chemistry 3 (1), 156-, 2020-11-06

...<jats:title>Abstract</jats:title><jats:p>Xeno nucleic acids, which are synthetic analogues of natural nucleic acids, have potential for use in nucleic acid drugs and as orthogonal genetic biopolymers and...

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Helen Hammer, Felix Schmidt, Philip Marx-Stoelting, Oliver Pötz, Albert Braeuning Archives of Toxicology 95 (1), 117-133, 2020-11-04

..., therefore, compared the hepatic levels of important CYP enzymes and transporters in different experimental systems in vivo and in vitro, namely Wistar rats, C57/Bl6 mice, mice humanized for the two xeno-sensing...

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Umezawa Akihiro, Sato Yoji, Kusakawa Shinji, Amagase Rin, Akutsu Hidenori, Nakamura Kazuaki, Kasahara Mureo, Matsubara Yoichi, Igarashi Takashi JMA Journal 3 (4), 287-294, 2020-10-15

...To avoid exposure of ESCs to animal products in culture media, a xeno-free cultivating system has been established....

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Furihata, Tomokazu, Miyaji, Hirofumi, Nishida, Erika, Kato, Akihito, Miyata, Saori, Shitomi, Kanako, Mayumi, Kayoko, Kanemoto, Yukimi, Sugaya, Tsutomu, Akasaka, Tsukasa Journal of biomedical materials research. Part B, Applied biomaterials 108 (7), 3033-3044, 2020-10

...Recombinant human collagen peptide, developed based on human collagen type I, contains an arginyl-glycyl-aspartic acid (RGD)-rich motif to enhance cell behavior and is anticipated as a xeno-free polymer...

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Elisabeth Kemter, Angelika Schnieke, Konrad Fischer, Peter J Cowan, Eckhard Wolf Current Opinion in Genetics & Development 64 60-65, 2020-10

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Tetsuya Ikemoto, Kazunori Tokuda, Yuma Wada, Luping Gao, Katsuki Miyazaki, Shinichiro Yamada, Yu Saito, Satoru Imura, Yuji Morine, Mitsuo Shimada Pancreas 49 (9), 1225-1231, 2020-09-08

...<jats:p>We isolated ADSCs from adipose tissue of 4 patients (one patient with T1DM and 3 nondiabetic patients), who underwent surgery and differentiated them into IPCs with using a 2-step xeno-antigen...

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Karen Duffy, Sebastian Arangundy-Franklin, Philipp Holliger BMC Biology 18 (1), 112-, 2020-09-02

...<jats:title>Abstract</jats:title><jats:p>Modified nucleic acids, also called xeno nucleic acids (XNAs), offer a variety of advantages for biotechnological applications and address some of the limitations...

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Juliette Seremak, Ali Eroglu Cryopreservation and Freeze-Drying Protocols 2180 569-579, 2020-08-15

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Takashi Yokoo, Shuichiro Yamanaka, Eiji Kobayashi Xenotransplantation 27 (5), e12622-, 2020-08-06

<jats:title>Abstract</jats:title><jats:p>Allogeneic kidney transplantation not only dramatically improves the prognosis and quality of life of patients with end‐stage renal disease who require …

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池口, 良輔, 青山, 朋樹, 松田, 秀一, 池谷, 真, Kamiya, Daisuke, Ando, Maki, Takeuchi, Hisataka, Akieda, Shizuka, Nakayama, Koichi, Matsuda, Shuichi, Ikeya, Makoto Scientific reports 10 (1), 2020-07-21

...The purpose of this study is to investigate the efficacy and mechanism of the Bio three-dimensional (3D) conduit composed of xeno-free human induced pluripotent stem cell-derived mesenchymal stem cells...

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Sadaki Mitsuzawa, Chengzhu Zhao, Ryosuke Ikeguchi, Tomoki Aoyama, Daisuke Kamiya, Maki Ando, Hisataka Takeuchi, Shizuka Akieda, Koichi Nakayama, Shuichi Matsuda, Makoto Ikeya Scientific Reports 10 (1), 2020-07-21

...The purpose of this study is to investigate the efficacy and mechanism of the Bio three-dimensional (3D) conduit composed of xeno-free human induced pluripotent stem cell–derived mesenchymal stem cells...

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Diem Huong Hoang, Tu Dac Nguyen, Hoang-Phuong Nguyen, Xuan-Hung Nguyen, Phuong Thi Xuan Do, Van Duc Dang, Phuong Thi Minh Dam, Hue Thi Hong Bui, Mai Quynh Trinh, Duc Minh Vu, Nhung Thi My Hoang, Liem Nguyen Thanh, Uyen Thi Trang Than Frontiers in Molecular Biosciences 7 119-, 2020-06-24

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Yoko Kawase-Koga, Yasuyuki Fujii, Daiki Yamakawa, Marika Sato, Daichi Chikazu Regenerative Therapy 14 128-135, 2020-06

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Denise Zujur, Kosuke Kanke, Shoko Onodera, Shoichiro Tani, Jenny Lai, Toshifumi Azuma, Xiaonan Xin, Alexander C. Lichtler, David W. Rowe, Taku Saito, Sakae Tanaka, Hideki Masaki, Hiromitsu Nakauchi, Ung-il Chung, Hironori Hojo, Shinsuke Ohba Regenerative Therapy 14 19-31, 2020-06

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VINAGRE Alexandra, RAMOS João, MARQUES Fernando, CHAMBINO Ana, MESSIAS Ana, MATA António Dental Materials Journal 39 (3), 397-406, 2020-05-27

...Two etch-and-rinse (Optibond™FL, Prime&Bond^®NT™) and three self-etch (Clearfil™SE Bond, Xeno^®III, Xeno^®V⁺) adhesive systems were evaluated on 159 occlusal restorations...

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Jonathan Bayerl, Muneef Ayyash, Tom Shani, Yair Manor, Ohad Gafni, Yael Kalma, Alejandro Aguilera-Castrejon, Mirie Zerbib, Hadar Amir, Daoud Sheban, Shay Geula, Nofar Mor, Leehee Weinberger, Vladislav Krupalnik, Bernardo Oldak, Nir Livnat, Shadi Tarazi, Shadi Tawil, Lior Lasman, Suhair Hanna, Noa Novershtern, Dalit Ben-Yosef, Sergey Viukov, Jacob H. Hanna 2020-05-24

...We establish that simultaneous inhibition of SRC-NFκB, WNT/ßCATENIN and PKC signalling pathways is essential for enabling expansion of teratoma competent fully naïve human PSCs in defined or xeno-free...

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Tomokazu Furihata, Hirofumi Miyaji, Erika Nishida, Akihito Kato, Saori Miyata, Kanako Shitomi, Kayoko Mayumi, Yukimi Kanemoto, Tsutomu Sugaya, Tsukasa Akasaka Journal of Biomedical Materials Research Part B: Applied Biomaterials 108 (7), 3033-3044, 2020-05-09

...:title><jats:p>Recombinant human collagen peptide, developed based on human collagen type I, contains an arginyl‐glycyl‐aspartic acid (RGD)‐rich motif to enhance cell behavior and is anticipated as a xeno‐free...

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Elisabetta Prina, Mahetab H. Amer, Laura Sidney, Maximilian Tromayer, Jonathan Moore, Robert Liska, Marina Bertolin, Stefano Ferrari, Andrew Hopkinson, Harminder Dua, Jing Yang, Ricky Wildman, Felicity R. A. J. Rose Advanced Biosystems 4 (6), 2000016-, 2020-04-24

...Human limbal epithelial stem cells (hLESCs) are seeded within the microniches in xeno‐free conditions to investigate their ability to repopulate the crypts and the expression of various differentiation...

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Bjorn John Stephen, Nidhi Pareek, Mohd Saeed, Mohd Adnan Kausar, Safikur Rahman, Manali Datta Frontiers in Immunology 11 2020-03-24

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Maria Elisabetta Federica Palamà, Georgina Margaret Shaw, Simonetta Carluccio, Daniele Reverberi, Laura Sercia, Luana Persano, Dario Pisignano, Katia Cortese, Francis Peter Barry, Josephine Mary Murphy, Chiara Gentili Frontiers in Bioengineering and Biotechnology 8 90-, 2020-02-14

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Tzu-Cheng Sung, Hsing-Fen Li, Akon Higuchi, S. Suresh Kumar, Qing-Dong Ling, Yu-Wen Wu, Thierry Burnouf, Michiyo Nasu, Akihiro Umezawa, Kuei-Fang Lee, Han-Chow Wang, Yung Chang, Shih-Tien Hsu Biomaterials 230 119638-, 2020-02

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Yohei Sato, Laura Passerini, Brian D Piening, Molly Javier Uyeda, Marianne Goodwin, Silvia Gregori, Michael P Snyder, Alice Bertaina, Maria‐Grazia Roncarolo, Rosa Bacchetta Clinical & Translational Immunology 9 (11), 2020-01

...Both allogeneic and autologous CD4<jats:sup>LVFOXP3</jats:sup> cells protect from xeno‐GvHD after two sequential infusions of effector T cells....

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Daisuke Kamiya, Nana Takenaka-Ninagawa, Souta Motoike, Mikihito Kajiya, Teppei Akaboshi, Chengzhu Zhao, Mitsuaki Shibata, Sho Senda, Yayoi Toyooka, Hidetoshi Sakurai, Hidemi Kurihara, Makoto Ikeya SSRN Electronic Journal 2020

DOI 被引用文献2件

RINNOVATI Riccardo, XENOS Socrate, BELTRAME Andrea, MARIGO Andrea, FORNI Giulia, MORINI Maria Ｊｏｕｒｎａｌ　ｏｆ　Ｅｑｕｉｎｅ　Ｓｃｉｅｎｃｅ 31 (3), 45-48, 2020

<p>A neurofibroma was excised from the subcutis on the medial side of the left thigh of a 15-year-old Warmblood gelding, which had shown lameness of the left hind limb. No other …

DOI Web Site Web Site ほか1件 参考文献7件

林 一広 ファルマシア 56 (3), 254-254, 2020

De novo protein designは計算化学を用いて自然界に存在しないタンパク質を新たに設計する手法であり，生物進化のみでは辿り着けない人智を超えたタンパク質の獲得に繋がる可能性が期待されている．立体配座の自由エネルギー状態を低く保つことで安定構造を持つ新規タンパク質の創製が達成されており，本分野は目覚しい進歩を遂げている．一方，立体配座の変換を伴うタンパク質の機能制御を志向した設計は…

DOI 医中誌

Hino Masato, Karasaki Noriko, Tatsuke Tsuneyuki, Morokuma Daisuke, Masuda Akitsu, Mon Hiroaki, Jae Man Lee, Kusakabe Takahiro Ｊｏｕｒｎａｌ　ｏｆ　Ｉｎｓｅｃｔ　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ　ａｎｄ　Ｓｅｒｉｃｏｌｏｇｙ 89 (1), 1_009-1_016, 2020

<p> In insect cell culture, a fetal bovine serum is often used to maintain the cellular physiological conditions, irrespective of its relatively high cost and unstable supply. Several serum-free …

DOI Web Site

Chengjuan Qu, Maria Brohlin, Paul J Kingham, Peyman Kelk Cell and Tissue Research 380 (1), 93-105, 2019-12-30

...<jats:title>Abstract</jats:title><jats:p>This study was aimed to investigate the effects of cGMP xeno-/serum-free medium (XSF, Irvine Scientific) on the properties of human dental pulp stem cells (DPSCs...

DOI PDF Web Site 被引用文献3件

A. M. Kolkmann, M. J. Post, M. A. M. Rutjens, A. L. M. van Essen, P. Moutsatsou Cytotechnology 72 (1), 111-120, 2019-12-28

...FBM™, TesR™ and Essential 8™ are commercially available xeno-free media developed for human PSCs and fibroblasts, with the highest potential to sustain bovine myoblast proliferation....

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Anna Zecin-Deren, Monika Lukomska-Szymanska, Agata Szczesio-Wlodarczyk, Ireneusz Piwonski, Jerzy Sokolowski, Barbara Lapinska Applied Sciences 10 (1), 124-, 2019-12-23

...Two universal (Single Bond Universal and Prime & Bond One Select) and two self-etch adhesives (Adper Easy One and Xeno V) were tested....

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Nicholas Castle, Ethan Kuehl, John Jones, Allan Treiman Meteoritics & Planetary Science 55 (1), 3-19, 2019-12-15

...The abundance of Ca in olivine in the xeno‐lithologies suggests a set of crustal, rather than deep mantle, lithologies....

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Jin Zhou, Yuan‐yuan Jiang, Huan Chen, Yi‐chao Wu, Li Zhang Cell Proliferation 53 (2), 2019-12-09

...Anti‐tumour activity of Tan‐Ⅰ was accessed by subcutaneous xeno‐transplanted tumour model of human ovarian cancer in nude mice....

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Anais Sahabian, Malte Sgodda, Ortwin Naujok, Rabea Dettmer, Julia Dahlmann, Felix Manstein, Tobias Cantz, Robert Zweigerdt, Ulrich Martin, Ruth Olmer Cells 8 (12), 1571-, 2019-12-04

...Optimal control during the differentiation process was attained in chemically-defined and xeno-free suspension culture, and high flexibility of the workflow was achieved by the introduction of an efficient...

DOI Web Site 被引用文献1件

Ya-Tzu Chen, May-Jywan Tsai, Nini Hsieh, Ming-Jei Lo, Meng-Jen Lee, Henrich Cheng, Wen-Cheng Huang Stem Cell Research & Therapy 10 (1), 2019-12

...Many studies have investigated MSC expansion efficacy of all kinds of culture medium formulations, such as growth factor-supplemented or xeno-free medium....

DOI PDF Web Site 被引用文献1件

Konrad Fischer, Beate Rieblinger, Rabea Hein, Riccardo Sfriso, Julia Zuber, Andrea Fischer, Bernhard Klinger, Wei Liang, Krzysztof Flisikowski, Mayuko Kurome, Valeri Zakhartchenko, Barbara Kessler, Eckhard Wolf, Robert Rieben, Reinhard Schwinzer, Alexander Kind, Angelika Schnieke Xenotransplantation 27 (1), e12560-, 2019-10-08

...We previously demonstrated efficient generation of pigs with multiple xeno‐transgenes placed at a single genomic locus....

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Kyungsook Kim, Sophia Bou-Ghannam, Hallie Thorp, David W. Grainger, Teruo Okano Scientific Reports 9 (1), 14415-, 2019-10-08

<jats:title>Abstract</jats:title><jats:p>Cell-based therapies are increasingly focused on allogeneic stem cell sources because of several advantages in eliminating donor variability (e.g., aging and …

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John Ong, Junzhe Zhao, Alexander W. Justin, Athina E. Markaki Biotechnology and Bioengineering 116 (12), 3457-3468, 2019-10-06

...In this minireview, we report current literature and critically discuss the synthesis, mechanical properties, biological effects and uses, biodegradability and cost of albumin hydrogels as a xeno‐free,...

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Thomas J. Bartosh, Joni H. Ylostalo Cells 8 (9), 1031-, 2019-09-05

...This study demonstrated that extensively expanded MSCs can be activated in 3D culture through spheroid formation in both FBS-containing and xeno-free media....

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Pavlos Texakalidis, Nektarios Charisis, Stefanos Giannopoulos, Dimitrios Xenos, Leonardo Rangel-Castilla, Apostolos K. Tassiopoulos, Pascal Jabbour, Jonathan A. Grossberg, Theofilos Machinis World Neurosurgery 129 503-513.e2, 2019-09

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Souta Motoike, Mikihito Kajiya, Nao Komatsu, Susumu Horikoshi, Tomoya Ogawa, Hisakatsu Sone, Shinji Matsuda, Kazuhisa Ouhara, Tomoyuki Iwata, Noriyoshi Mizuno, Tsuyoshi Fujita, Makoto Ikeya, Hidemi Kurihara International Journal of Molecular Sciences 20 (16), 3970-, 2019-08-15

...Human bone marrow-derived MSCs were cultured in xeno-free/serum-free medium....

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Ana Engler‐Pinto, Selma Siéssere, Ana Calefi, Luiz Oliveira, Edilson Ervolino, Sérgio de Souza, Flávia Furlaneto, Michel Reis Messora Clinical Oral Implants Research 30 (10), 962-976, 2019-07-28

...In PRF, XENO, and PRF‐XENO groups, defects were filled with 0.1 ml of L‐PRF, 0.1 ml of XENO, and a mixture of 0.1 ml of L‐PRF plus 0.1 ml of XENO, respectively....

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Ikemoto, Tetsuya, Feng, Rui, Iwahashi, Shu-ichi, Yamada, Shinichiro, Saito, Yu, Morine, Yuji, Imura, Satoru, Matsuhisa, Munehide, Shimada, Mitsuo Scientific Reports 9 10759-, 2019-07-24

...We established a 3D culture using a human recombinant peptide (RCP) petaloid μ-piece with xeno-antigen free reagents....

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John C. Chaput, Piet Herdewijn Angewandte Chemie International Edition 58 (34), 11570-11572, 2019-07-19

...<jats:title>Abstract</jats:title><jats:p>The term “xeno‐nucleic acids”, abbreviated XNA, has grown in popularity to the point that it has become a catch‐all phrase for almost any unnatural nucleic acid...

DOI Web Site Web Site ほか2件 被引用文献8件

John C. Chaput, Piet Herdewijn Angewandte Chemie 131 (34), 11694-11696, 2019-07-19

...<jats:title>Abstract</jats:title><jats:p>Der Begriff der “xeno‐Nukleinsäuren”, abgekürzt als XNA, hat in der vergangenen Zeit stetig an Popularität gewonnen und ist heutzutage zu einem Sammelbegriff für...

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Mitsuhiro Sekijima, Hisashi Sahara, Akira Shimizu, Takehiro Iwanaga, Takahiro Murokawa, Yuichi Ariyoshi, Thomas Pomposelli, Mohsen Khosravi Maharlooei, Megan Sykes, Kazuhiko Yamada Xenotransplantation 26 (6), 2019-07-10

...We first prepared the Hyb‐thy in the donor pigs 2‐3 weeks before xeno‐Tx. We performed six cases of Hyb‐thy preparation in six juvenile miniature swine....

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Hélène Serra, Martin Scholze, Rolf Altenburger, Wibke Busch, Hélène Budzinski, François Brion, Selim Aït-Aïssa Chemosphere 227 334-344, 2019-07

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Ryo Ohta, Ryohichi Sugimura, Akira Niwa, Megumu K. Saito Journal of Visualized Experiments (148) 2019-06-16

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Esraa Mohamed Abdel Moniem, Mona Mahmoud EL-Batran, Ahmed Mahmoud Halawa, Dina Hazem Gomaa, Ghada Nour Eldeen, Riham Mohamed Aly Stem Cell Investigation 6 15-15, 2019-06

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Georgy Sagaradze, Olga Grigorieva, Peter Nimiritsky, Nataliya Basalova, Natalia Kalinina, Zhanna Akopyan, Anastasia Efimenko International Journal of Molecular Sciences 20 (7), 1656-, 2019-04-03

...We manufactured 36 MSC-CM samples based on different xeno-free serum-free chemically defined media (DMEM-LG or MSC NutriStem® XF) using original protocols and considered total concentrations of regeneration-associated...

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Bettina Mannerström, Riku O. Paananen, Ahmed G. Abu-Shahba, Jukka Moilanen, Riitta Seppänen-Kaijansinkko, Sippy Kaur Scientific Reports 9 (1), 2019-04-02

...Commercially available serum- and xeno-free defined media were also screened for small ncRNA contamination....

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Yulius Hermanto, Takakuni Maki, Yasushi Takagi, Susumu Miyamoto, Jun Takahashi Journal of Neuroscience Research 97 (7), 828-845, 2019-03-20

...In the present study, we established a xeno‐free system to induce forebrain OPCs from hPSCs....

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Tomoyuki Kawase, Masaki Nagata, Kazuhiro Okuda, Takashi Ushiki, Yoko Fujimoto, Mari Watanabe, Akira Ito, Koh Nakata International Journal of Molecular Sciences 20 (5), 1053-, 2019-02-28

...These findings suggest that the novel culture medium featuring PRFext offers advantages by shortening the culture period and excluding possible risks associated with xeno-factors without negatively altering...

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Ulf Diekmann, Hanna Wolling, Rabea Dettmer, Isabell Niwolik, Ortwin Naujok, Falk F. R. Buettner Scientific Reports 9 (1), 2019-01-30

...Next, fetal calf serum and bovine serum albumin present in the standard medium were replaced by a custom-made and xeno-free B-27....

DOI PDF Web Site 被引用文献1件

Bin Jiang, Li Yan, Xiaoyan Wang, Enqin Li, Kyle Murphy, Kyle Vaccaro, Yingcui Li, Ren-He Xu Stem Cells 37 (5), 572-581, 2019-01-21

...shown that hPSCs can differentiate in two dimensions or three dimensions to MSCs (ps-MSCs) via embryonic (mesoderm and neural crest) or extraembryonic (trophoblast) cell types under serum-containing or xeno-free...

DOI PDF Web Site ほか2件 被引用文献1件

Anna Zecin-Deren, Jerzy Sokolowski, Agata Szczesio-Wlodarczyk, Ireneusz Piwonski, Monika Lukomska-Szymanska, Barbara Lapinska Molecules 24 (2), 345-, 2019-01-18

...The highest SBS was obtained for Single Bond Universal applied in three layers, while the lowest, for Xeno V applied in one layer....

DOI Web Site 被引用文献1件

Kentaro Nakamura Current Stem Cell Research & Therapy 14 (1), 52-56, 2019-01-14

...In the trend, a cell transplantation platform named CellSaic, which is a combination of xeno-free recombinant scaffolds in a cell aggregate-like shape, was developed....

DOI Web Site 被引用文献9件

Madison McGrath, Edmund Tam, Martina Sladkova, Athbah AlManaie, Matthew Zimmer, Giuseppe Maria de Peppo Stem Cell Research & Therapy 10 (1), 2019-01-11

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Noel Ye Naung, Warwick Duncan, Rohana De Silva, Dawn Coates European Journal of Oral Sciences 127 (2), 99-111, 2019-01-07

...In this study we localized, quantified, and characterized <jats:styled-content style="fixed-case">MSC</jats:styled-content>s from palatal periosteum cultured in serum‐free, xeno‐free Essential 8 medium...

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Tzu-Cheng Sung, Cheng-Hui Liu, Wei-Lun Huang, Yu-Chun Lee, S. Suresh Kumar, Yung Chang, Qing-Dong Ling, Shih-Tien Hsu, Akon Higuchi Biomaterials Science 7 (12), 5467-5481, 2019

...<p>Efficient differentiation of human ES and iPS cells into cardiomyocytes was successively developed on biomaterials under xeno-free conditions.</p>...

DOI Web Site 被引用文献1件

Li-Hua Chen, Tzu-Cheng Sung, Henry Hsin-Chung Lee, Akon Higuchi, Huan-Chiao Su, Kuan-Ju Lin, Yu-Ru Huang, Qing-Dong Ling, S. Suresh Kumar, Abdullah A. Alarfaj, Murugan A. Munusamy, Michiyo Nasu, Da-Chung Chen, Shih-Tien Hsu, Yung Chang, Kuei-Fang Lee, Han-Chow Wang, Akihiro Umezawa Biomaterials Science 7 (10), 4345-4362, 2019

...<p>Xeno-free culture and cardiomyocyte differentiation of human embryonic stem cells on vitronectin-grafted hydrogels by adjusting surface charge and elasticity.</p>...

DOI Web Site 被引用文献2件

LEE Haesun, HWANG In-Sul, PARK Mi-Ryung, KWAK Tae-Uk, BYUN Sung June, LEE Hwi-Cheul, YANG Hyeon, OCK Sun-A, HWANG Seongsoo, OH Keon Bong 日本繁殖生物学会　講演要旨集 112 (0), P-101-P-101, 2019

...In addition, simultaneous expression of thrombomodulin (TBM) in the pig was reported to contribute extended survival of cardiac xeno-grafted monkey....

DOI

Lars Burdorf, Agnes M. Azimzadeh, Richard N. Pierson Current Opinion in Organ Transplantation 23 (6), 621-627, 2018-12

...xenotransplantation, and discuss possible additional genetic modifications and other interventions that may further advance the use of pulmonary xenografts towards clinical applications based on known mechanisms of xeno...

DOI Web Site 被引用文献1件

Jastin Link, Cosima Thon, Denny Schanze, Ruta Steponaitiene, Juozas Kupcinskas, Martin Zenker, Ali Canbay, Peter Malfertheiner, Alexander Link Molecular Nutrition & Food Research 63 (2), 2018-11-20

<jats:sec><jats:title>Scope</jats:title><jats:p>Diet is amongst the most crucial factors contributing to the multistep process of carcinogenesis. The role of exogenous microRNAs (miRNAs) is still …

DOI Web Site Web Site ほか1件 被引用文献1件

André L. Rodrigues, Carlos A. V. Rodrigues, Ana R. Gomes, Sara F. Vieira, Sara M. Badenes, Maria M. Diogo, Joaquim M.S. Cabral Biotechnology Journal 14 (4), 2018-11-12

...These results are validated with a second cell line and the culture is successfully adapted to fully xeno‐free conditions....

DOI Web Site Web Site ほか1件 被引用文献1件

Hiya Lahiri, Sourav Mishra, Rupa Mukhopadhyay Langmuir 35 (27), 8875-8888, 2018-11-06

DOI Web Site 被引用文献1件

Monica Suryana Tjin, Alvin Wen Choong Chua, Aida Moreno-Moral, Li Yen Chong, Po Yin Tang, Nathan Peter Harmston, Zuhua Cai, Enrico Petretto, Bien Keem Tan, Karl Tryggvason Nature Communications 9 (1), 4432-, 2018-10-30

...Herein, we report a completely xeno-free and defined culture system utilizing these laminins which enables robust expansion of adult human skin keratinocytes....

DOI PDF Web Site 被引用文献3件

Laura Beani, Federico Cappa, Fabio Manfredini, Marco Zaccaroni PLOS ONE 13 (10), e0205201-, 2018-10-24

DOI Web Site 被引用文献1件

S. Chafino, D. López-Escardó, G. Benelli, H. Kovac, E. Casacuberta, X. Franch-Marro, J. Kathirithamby, D. Martín Scientific Reports 8 (1), 14176-, 2018-09-21

...In <jats:italic>Xenos vesparum</jats:italic> Rossi (Strepsiptera: Stylopidae), a derived species of the holometabolous endoparasitic order Strepsiptera, neotenic females reach sexual maturity without the...

DOI PDF Web Site 被引用文献5件

Heather Akin, Sara K. Yeo, Christopher D. Wirz, Dietram A. Scheufele, Dominique Brossard, Michael A. Xenos, Elizabeth A. Corley Journal of Responsible Innovation 6 (1), 50-74, 2018-09-12

DOI Web Site 被引用文献1件

Yong Liu, Hai Wei Xu, Lei Wang, Shi Ying Li, Cong Jian Zhao, Jie Hao, Qi You Li, Tong Tao Zhao, Wei Wu, Yi Wang, Qi Zhou, Cheng Qian, Liu Wang, Zheng Qin Yin Cell Discovery 4 (1), 2018-09-11

...We developed a clinical-grade human embryonic stem cell (hESC) line, Q-CTS-hESC-2, under xeno-free conditions that differentiated into retinal pigment epithelial cells (Q-CTS-hESC-2-RPE)....

DOI PDF Web Site 被引用文献3件

Sangeetha Kandoi, Praveen kumar L, Bamadeb Patra, Prasanna Vidyasekar, Divya Sivanesan, Vijayalakshmi S., Rajagopal K., Rama Shanker Verma Scientific Reports 8 (1), 2018-08-20

...We used platelet lysate (PL) as a xeno-free, allogeneic replacement for FBS and compared the biological and functional characteristics of MSC processed and expanded with PL and FBS by explant and enzymatic...

DOI PDF Web Site 被引用文献1件

Christopher M. Whitford, Saskia Dymek, Denise Kerkhoff, Camilla März, Olga Schmidt, Maximilian Edich, Julian Droste, Boas Pucker, Christian Rückert, Jörn Kalinowski Journal of Biological Engineering 12 (1), 2018-08-14

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Carlos AV Rodrigues, Teresa P Silva, Diogo ES Nogueira, Tiago G Fernandes, Yas Hashimura, Robin Wesselschmidt, Maria Margarida Diogo, Brian Lee, Joaquim MS Cabral Journal of Chemical Technology & Biotechnology 93 (12), 3597-3606, 2018-07-13

...</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>In this work, the novel vertical‐wheel single‐use bioreactors were used for the first time for the expansion of hiPSC under xeno‐free...

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RC Ferreira-Filho, C Ely, RC Amaral, JA Rodrigues, J-F Roulet, A Cassoni, AF Reis Operative Dentistry 43 (4), 391-397, 2018-07-01

...</jats:sec> <jats:sec> <jats:title>Methods and Materials:</jats:title> <jats:p>Four adhesive systems were used to perform IDS: a one-step self-etch (Xeno...

DOI PDF 被引用文献2件

Christopher J. Rivard, Tatsu Tanabe, Miguel A. Lanaspa, Hironosuke Watanabe, Shunichiro Nomura, Ana Andres-Hernando, Krystle Garth, Mitsuhiro Sekijima, Takuji Ishimoto, Yuichi Ariyoshi, Gabriela E. Garcia, Jigesh Shah, Boyd Lennan, Masayuki Tasaki, Thomas Pomposelli, Akira Shimizu, David H. Sachs, Richard J. Johnson, Kazuhiko Yamada Transplant International 31 (10), 1164-1177, 2018-06-05

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Francesco Agostini, Francesca Maria Rossi, Donatella Aldinucci, Monica Battiston, Elisabetta Lombardi, Stefania Zanolin, Samuele Massarut, Pier Camillo Parodi, Alessandro Da Ponte, Giovanni Tessitori, Barbara Pivetta, Cristina Durante, Mario Mazzucato Stem Cell Research & Therapy 9 (1), 130-, 2018-05-11

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Boglárka Zámbó, Zsuzsa Bartos, Orsolya Mózner, Edit Szabó, György Várady, Gyula Poór, Márton Pálinkás, Hajnalka Andrikovics, Tamás Hegedűs, László Homolya, Balázs Sarkadi Scientific Reports 8 (1), 2018-05-10

...<jats:title>Abstract</jats:title><jats:p>The ABCG2 membrane protein is a key xeno- and endobiotic transporter, modulating the absorption and metabolism of pharmacological agents and causing multidrug resistance...

DOI PDF Web Site 被引用文献1件

S.J. Lee, J.S. Kim, H.K. Chee, I.J. Yun, K.S. Park, H.S. Yang, J.H. Park Transplantation Proceedings 50 (4), 1167-1171, 2018-05

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Jeewaka E. Mohotti, Nicole S. Carter, Victor Jia Wei Zhang, Leon T. Lai, Christopher Xenos, Hamed Asadi, Ronil V. Chandra Journal of Neurosurgery: Pediatrics 21 (5), 471-477, 2018-05

<jats:p>Intracranial aneurysms in the neonate, presenting in the first 4 weeks of life, are exceedingly rare. They appear to have characteristics, including presentation and location, that vary from …

DOI XML XML 被引用文献1件

Hironosuke Watanabe, Hisashi Sahara, Shunichiro Nomura, Tatsu Tanabe, Dilrukshi K. Ekanayake‐Alper, Lennan K. Boyd, Nathan J. Louras, Arsenoi Asfour, Makenzie A. Danton, Siu‐Hong Ho, Scott J. Arn, Robert J. Hawley, Akira Shimizu, Takeshi Nagayasu, David Ayares, Marc I. Lorber, Megan Sykes, David H. Sachs, Kazuhiko Yamada Xenotransplantation 25 (5), e12391-, 2018-03-12

...Here, we report our initial results of pig‐to‐baboon xeno‐lung transplantation (<jats:styled-content style="fixed-case">XLT</jats:styled-content>x)....

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Tzu-Cheng Sung, Hsing-Fen Li, Akon Higuchi, Qing-Dong Ling, Jia-Sin Yang, Yeh-Chia Tseng, Chih-Hsien Pan Pan, Abdullah A. Alarfaj, Murugan A. Munusamy, Suresh Kumar, Shih-Tien Hsu, Kadarkarai Murugan Journal of Visualized Experiments (132) 2018-02-03

DOI Web Site

Amélie Vantaux, Reingsey Samreth, Eakpor Piv, Nimol Khim, Saorin Kim, Laura Berne, Sophy Chy, Dysoley Lek, Sovannaroth Siv, Walter R Taylor, Didier Ménard The Journal of Infectious Diseases 217 (10), 1561-1568, 2018-01-31

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Yi Deng, Shicheng Wei, Lei Yang, Weizhong Yang, Matthew S. Dargusch, Zhi‐Gang Chen Advanced Functional Materials 28 (11), 2018-01-17

...Such a well‐defined, xeno‐free 2D engineered microenvironment not only helps to accelerate the clinical development of hiPSCs, but also provides a safe and robust platform for the generation of osteoblast‐like...

DOI Web Site Web Site ほか2件 被引用文献1件

Daimon Atsushi, Tomoda Kiichiro, Morihara Yoshifumi, Asahi Michio 日本薬理学会年会要旨集 WCP2018 (0), PO4-4-13-, 2018

...Second, we attempted to differentiate the ES cell lines into EPC - like cells with a xeno-free method and could easily propagate enough quantities of the EPC-like cells for transplantations....

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Heidi Hongisto, Tanja Ilmarinen, Meri Vattulainen, Alexandra Mikhailova, Heli Skottman Stem Cell Research & Therapy 8 (1), 291-, 2017-12

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Yulius Hermanto, Tadashi Sunohara, Ahmad Faried, Yasushi Takagi, Jun Takahashi, Takakuni Maki, Susumu Miyamoto Journal of Neuroscience Research 96 (5), 863-874, 2017-11-07

...Strict regulation of cell therapy development requires the xeno‐free condition to eliminate clinical complications....

DOI Web Site Web Site 被引用文献1件

Hisashi Sahara, Mitsuhiro Sekijima, Yuichi Ariyoshi, Akihiro Kawai, Kohei Miura, Shiori Waki, Louras Nathan, Yusuke Tomita, Takehiro Iwanaga, Kazuaki Nakano, Hitomi Matsunari, Hiroshi Date, Hiroshi Nagashima, Akira Shimizu, Kazuhiko Yamada Xenotransplantation 25 (1), 2017-10-25

...Although <jats:styled-content style="fixed-case">CO</jats:styled-content> treatment did not prolong overall xeno lung graft survival, the recipient/donor <jats:styled-content style="fixed-case">CO</jats...

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James O.S. Hackland, Tom J.R. Frith, Oliver Thompson, Ana Marin Navarro, Martin I. Garcia-Castro, Christian Unger, Peter W. Andrews Stem Cell Reports 9 (4), 1043-1052, 2017-10

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Thierry Carrel, Lars Englberger, Jürg Schmidli General Thoracic and Cardiovascular Surgery 67 (1), 44-52, 2017-09-25

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Jun Wu, Marcela Vilarino, Keiichiro Suzuki, Daiji Okamura, Yanina Soledad Bogliotti, Insung Park, Joan Rowe, Bret McNabb, Pablo Juan Ross, Juan Carlos Izpisua Belmonte Scientific Reports 7 (1), 2017-09-05

...co-delivery of Cas9 mRNA and dual sgRNAs targeting the <jats:italic>PDX1</jats:italic> gene, which when combined with chimeric-competent human pluriopotent stem cells may serve as a suitable platform for the xeno-generation...

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Dionysios Xenos, Marija Kamceva, Simone Tomasi, Jessica A Cardin, Michael L Schwartz, Flora M Vaccarino Cerebral Cortex 28 (10), 3399-3413, 2017-08-18

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Dietram A. Scheufele, Michael A. Xenos, Emily L. Howell, Kathleen M. Rose, Dominique Brossard, Bruce W. Hardy Science 357 (6351), 553-554, 2017-08-11

<jats:p>Although views on human genome editing differ, all want public engagement</jats:p>

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Zhuochao Zhang, Xiao Li, Hong Zhang, Xuan Zhang, Hui Chen, Dengke Pan, Hongchen Ji, Liang Zhou, Juan Ling, Jingshi Zhou, Shuqiang Yue, Desheng Wang, Zhaoxu Yang, Kaishan Tao, Kefeng Dou Xenotransplantation 24 (5), 2017-07-17

...To better elucidate the process of inflammation in liver xenograft recipients, we utilized a modified heterotopic auxiliary liver xenotransplantation model for xeno‐immunological research....

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Naresh Polisetti, Lydia Sorokin, Naoki Okumura, Noriko Koizumi, Shigeru Kinoshita, Friedrich E. Kruse, Ursula Schlötzer-Schrehardt Scientific Reports 7 (1), 5152-, 2017-07-11

...Thus, the incorporation of chemically defined LN-511-E8 into biosynthetic scaffolds represents a promising approach for xeno-free corneal epithelial tissue engineering for ocular surface reconstruction...

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George Adamides, Christos Katsanos, Yisrael Parmet, Georgios Christou, Michalis Xenos, Thanasis Hadzilacos, Yael Edan Applied Ergonomics 62 237-246, 2017-07

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M. Rigante, G. La Rocca, L. Lauretti, G.Q. D’Alessandris, A. Mangiola, C. Anile, A. Olivi, G. Paludetti Acta Otorhinolaryngologica Italica 37 (3), 237-241, 2017-06

...I pazienti sono stati operati attraverso un approccio transnasale transfenoidale endoscopico, utilizzando un endoscopio Olympus NBI 4K UHD con ottica 4 mm 0 ° Ultra Telescope, lampada allo xeno 300 W (...

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Jan W. V. van Dijken, Ulla Pallesen European Journal of Oral Sciences 125 (4), 303-309, 2017-05-19

...In all cavities a single‐step self‐etch adhesive (Xeno V) was applied....

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Arantxa Blázquez-Prunera, José María Díez, Rodrigo Gajardo, Salvador Grancha Stem Cell Research & Therapy 8 (1), 103-, 2017-04-27

DOI PDF 被引用文献3件

Stavros T. Ponis, Pantelia-Anna Papanikolaou, Petros Katimertzoglou, Athanasia C. Ntalla, Konstantinos. I. Xenos Journal of Cleaner Production 149 1268-1277, 2017-04

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Michał Stefan Lach, Joanna P. Wroblewska, Ewelina Augustyniak, Katarzyna Kulcenty, Wiktoria Maria Suchorska Stem Cell Research 20 34-37, 2017-04

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Yen-Ming Chen, Li-Hua Chen, Meng-Pei Li, Hsing-Fen Li, Akon Higuchi, S. Suresh Kumar, Qing-Dong Ling, Abdullah A. Alarfaj, Murugan A. Munusamy, Yung Chang, Giovanni Benelli, Kadarkarai Murugan, Akihiro Umezawa Scientific Reports 7 (1), 45146-, 2017-03-23

...<jats:title>Abstract</jats:title><jats:p>Establishing cultures of human embryonic (ES) and induced pluripotent (iPS) stem cells in xeno-free conditions is essential for producing clinical-grade cells....

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R E Piddock, N Loughran, C R Marlein, S D Robinson, D R Edwards, S Yu, G E Pillinger, Z Zhou, L Zaitseva, M J Auger, S A Rushworth, K M Bowles Blood Cancer Journal 7 (3), e539-e539, 2017-03-10

...activation assays only dual PI3kδ/γ inhibition was able to induce MM apoptosis. shRNA lentiviral-mediated targeting of either PI3Kδ or PI3Kγ alone, or both in combination, increased survival of NSG mice xeno-transplanted...

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Sacha Reichman, Amélie Slembrouck, Giuliana Gagliardi, Antoine Chaffiol, Angélique Terray, Céline Nanteau, Anais Potey, Morgane Belle, Oriane Rabesandratana, Jens Duebel, Gael Orieux, Emeline F. Nandrot, José-Alain Sahel, Olivier Goureau Stem Cells 35 (5), 1176-1188, 2017-02-20

...To this purpose, we have developed a two-step xeno-free/feeder-free (XF/FF) culture system to efficiently differentiate hiPSCs into retinal cells....

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Alan Morris Nature Reviews Endocrinology 13 (4), 190-190, 2017-02-10

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Feng Huang, Maogen Chen, Weiqian Chen, Jian Gu, Jia Yuan, Yaoqiu Xue, Junlong Dang, Wenru Su, Julie Wang, Homayoun H. Zadeh, Xiaoshun He, Limin Rong, Nancy Olsen, Song Guo Zheng Frontiers in Immunology 8 68-, 2017-02-02

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Hiroki Uchida, Kuniyasu Niizuma, Yoshihiro Kushida, Shohei Wakao, Teiji Tominaga, Cesario V. Borlongan, Mari Dezawa Stroke 48 (2), 428-435, 2017-02

...</jats:p> </jats:sec> <jats:sec> <jats:title>Methods—</jats:title> <jats:p>We conducted mechanism-based experiments by transplanting serum/xeno-free cultured-human...

DOI Web Site 被引用文献29件 参考文献30件

Gerard F. Curley, Mirjana Jerkic, Steve Dixon, Grace Hogan, Claire Masterson, Daniel O’Toole, James Devaney, John G. Laffey Critical Care Medicine 45 (2), e202-e212, 2017-02

...We wished to compare mesenchymal stem/stromal cells from human umbilical cord, grown in xeno-free conditions, with mesenchymal stem/stromal cells from human bone marrow, in a rat model of <jats:italic...

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A. Blázquez-Prunera, C. R. Almeida, M. A. Barbosa Stem Cells International 2017 1-12, 2017

...For their use in human therapies, it is necessary to culture hMSC in xeno-free conditions....

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Chika Miyagi-Shiohira, Naoya Kobayashi, Issei Saitoh, Masami Watanabe, Yasufumi Noguchi, Masayuki Matsushita, Hirofumi Noguchi Cell Medicine 9 (1-2), 15-20, 2017-01

...free), and TC protector (serum free, xeno free)....

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Mimmi Patrikoski, Michelle Hui Ching Lee, Laura Mäkinen, Xiu Min Ang, Bettina Mannerström, Michael Raghunath, Susanna Miettinen Stem Cells International 2017 1-14, 2017

...to support adipose stem cell (ASC) proliferation, metabolism, and multilineage differentiation was studied under different conditions: fetal bovine serum- (FBS-) and human serum- (HS-) based media and xeno...

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Elias Uhlin, Harriet Rönnholm, Kelly Day, Malin Kele, Kristiina Tammimies, Sven Bölte, Anna Falk Stem Cell Research 18 22-25, 2017-01

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J. Behaegel, S. Ní Dhubhghaill, C. Koppen, N. Zakaria Stem Cells International 2017 1-11, 2017

...Good manufacturing practice and xeno-free culture protocols could reduce potential health risks but are not yet a common practice worldwide....

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J-H Jang, H-Y Kim, S-M Shin, C-O Lee, DS Kim, K-K Choi, S-Y Kim Operative Dentistry 42 (1), 19-29, 2017-01-01

...The adhesive systems were Clearfil SE bond (CS), a two-step self-etch adhesive, and Xeno V (XE), a one-step self-etch adhesive....

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M. Cimino, R. M. Gonçalves, C. C. Barrias, M. C. L. Martins Stem Cells International 2017 1-13, 2017

...However, regulatory guidelines encourage novel xeno-free alternatives to define safer and standardized protocols for hMSC expansion that preserve their intrinsic therapeutic potential....

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Kunihiko Morihiro, Yuuya Kasahara, Satoshi Obika Molecular BioSystems 13 (2), 235-245, 2017

...<p>Xeno nucleic acids (XNAs) are a group of chemically modified nucleic acid analogues that have been applied to various biological technologies such as antisense oligonucleotides, siRNAs and aptamers....

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井手 健太郎, 坂井 寛, 田中 友加, 大段 秀樹 Organ Biology 24 (2), 143-146, 2017

...Therefore, TLR-MyD88 signaling can be a therapeutic target in managing the xeno-carbohydrate antigen-reactive B cell response....

DOI 医中誌

Xiaoping Bao, Xiaojun Lian, Timothy A. Hacker, Eric G. Schmuck, Tongcheng Qian, Vijesh J. Bhute, Tianxiao Han, Mengxuan Shi, Lauren Drowley, Alleyn T. Plowright, Qing-Dong Wang, Marie-Jose Goumans, Sean P. Palecek Nature Biomedical Engineering 1 (1), 2016-12-05

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Nathan T Orr, Daniel L Davenport, David J Minion, Eleftherios S Xenos Vascular 25 (4), 339-345, 2016-12-05

<jats:sec><jats:title>Objective</jats:title><jats:p> Endoluminal aortic aneurysm repair is suitable within certain anatomic specifications. This study aims to compare 30-day outcomes of endovascular …

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Lothar Lauterboeck, Debapriya Saha, Anamika Chatterjee, Nicola Hofmann, Birgit Glasmacher Biopreservation and Biobanking 14 (6), 530-538, 2016-12

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Meng Fatt Leong, Hong Fang Lu, Tze Chiun Lim, Chan Du, Nina K.L. Ma, Andrew C.A. Wan Acta Biomaterialia 46 266-277, 2016-12

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Malin Kele, Kelly Day, Harriet Rönnholm, Jens Schuster, Niklas Dahl, Anna Falk Stem Cell Research 17 (3), 474-478, 2016-11

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中瀬 悠太, 野村 周平, 枝廣 雅美, 櫛引 敬嗣 昆蟲．ニューシリーズ 19 (4), 139-144, 2016-10-05

<p>キイロスズメバチの働き蜂と，それに内部寄生したスズメバチネジレバネの雌雄それぞれ1個体をヨウ素エタノールによるヨウ素染色を行ったのちヘキサメチルジシラザンにより乾燥標本とし，マイクロCTを用いて観察を行った．その結果，スズメバチの内部組織，および体内のネジレバネについて非破壊で詳細な観察を行うことができた．スズメバチの体内の筋肉，消化管，針，寄生しているネジレバネの雄の囲蛹の内部の蛹の筋肉…

DOI Web Site

Mien T.X. Nguyen, Elena Okina, Xiaoran Chai, Kok Hian Tan, Outi Hovatta, Sujoy Ghosh, Karl Tryggvason Stem Cell Reports 7 (4), 802-816, 2016-10

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Sylwia Bobis-Wozowicz, Katarzyna Kmiotek, Karolina Kania, Elzbieta Karnas, Anna Labedz-Maslowska, Malgorzata Sekula, Sylwia Kedracka-Krok, Jacek Kolcz, Dariusz Boruczkowski, Zbigniew Madeja, Ewa K. Zuba-Surma Journal of Molecular Medicine 95 (2), 205-220, 2016-09-16

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Marcelo Araya‐Salas, Grace Smith‐Vidaurre Methods in Ecology and Evolution 8 (2), 184-191, 2016-09-08

...We analyse geographic variation in long‐billed hermit hummingbirds (<jats:italic>Phaethornis longirostris</jats:italic>) songs obtained from Xeno‐Canto....

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Masaaki Watanabe, Helen Zemack, Helene Johansson, Louise Hagbard, Carl Jorns, Meng Li, Ewa Ellis PLOS ONE 11 (9), e0161383-, 2016-09-06

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LS Lopes, FS Calazans, R Hidalgo, LL Buitrago, F Gutierrez, A Reis, AD Loguercio, MO Barceleiro Operative Dentistry 41 (5), 465-480, 2016-09-01

...</jats:p> <jats:p>Conclusions: The six-month clinical behavior of Xeno Select Universal Adhesive depends on the bonding strategy used....

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Miho Isoda, Jun Kohyama, Akio Iwanami, Tsukasa Sanosaka, Keiko Sugai, Ryo Yamaguchi, Takuya Matsumoto, Masaya Nakamura, Hideyuki Okano Neuroscience Research 110 18-28, 2016-09

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Parul Choudhary, Heather Booth, Alex Gutteridge, Beata Surmacz, Irene Louca, Juliette Steer, Julie Kerby, Paul John Whiting Stem Cells Translational Medicine 6 (2), 490-501, 2016-08-24

...Here we show development of an efficient method for deriving homogeneous RPE populations in a period of 45 days using an adherent, monolayer system and defined xeno-free media and matrices....

DOI PDF Web Site 被引用文献1件

Yongjia Fan, Fan Zhang, Emmanuel S. Tzanakakis ACS Biomaterials Science & Engineering 3 (8), 1510-1518, 2016-08-09

DOI Web Site 被引用文献2件

Michael A. Cacciatore, Nick Browning, Dietram A. Scheufele, Dominique Brossard, Michael A. Xenos, Elizabeth A. Corley Public Understanding of Science 27 (1), 11-28, 2016-07-25

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Sara Pijuan-Galitó, Christoffer Tamm, Jens Schuster, Maria Sobol, Lars Forsberg, Catherine L. R. Merry, Cecilia Annerén Nature Communications 7 (1), 2016-07-13

...Here we present a completely defined, xeno-free medium that supports long-term propagation of hPS cells on uncoated tissue culture plastic....

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Leona Yi-Fan Su, Michael A. Cacciatore, Xuan Liang, Dominique Brossard, Dietram A. Scheufele, Michael A. Xenos Information, Communication & Society 20 (3), 406-427, 2016-05-09

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CE Pena, JA Rodrigues, C Ely, M Giannini, AF Reis Operative Dentistry 41 (3), 249-257, 2016-05-01

...One restoration was lost during the trial (Xeno V+ etch; p&gt;0.05)....

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Alexandros Tsironis, Christos Katsanos, Michail Xenos 2016 IEEE Global Engineering Education Conference (EDUCON) 2016-04

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Huimin Zhai, Michael Hrabar, Regine Gries, Gerhard Gries, Robert Britton Chemistry – A European Journal 22 (18), 6190-6193, 2016-03-22

...<jats:title>Abstract</jats:title><jats:p>The sex pheromone of the endoparasitoid insect <jats:italic>Xenos peckii</jats:italic> (Strepsiptera: Xenidae) was recently identified as (7<jats:italic>E</jats...

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Sara M. Badenes, Tiago G. Fernandes, Cláudia S. M. Cordeiro, Shayne Boucher, David Kuninger, Mohan C. Vemuri, Maria Margarida Diogo, Joaquim M. S. Cabral PLOS ONE 11 (3), e0151264-, 2016-03-21

DOI Web Site 被引用文献5件

Ryoichi Miyamoto, Tatsuya Oda, Shinji Hashimoto, Tomohiro Kurokawa, Yuki Inagaki, Osamu Shimomura, Yusuke Ohara, Keiichi Yamada, Yoshimasa Akashi, Tsuyoshi Enomoto, Mikio Kishimoto, Hideto Yanagihara, Eiji Kita, Nobuhiro Ohkohchi Cancer Science 107 (4), 514-520, 2016-03-04

...amounts (scarce, <jats:styled-content style="fixed-case">MIAP</jats:styled-content>aCa‐2; moderate, Bx<jats:styled-content style="fixed-case">PC</jats:styled-content>‐3; and abundant, Capan‐1 and Ope‐xeno...

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Hyunah Lee, Donggyu Nam, Jae-Kyung Choi, Marcos J. Araúzo-Bravo, Soon-Yong Kwon, Holm Zaehres, Taehee Lee, Chan Young Park, Hyun-Wook Kang, Hans R. Schöler, Jeong Beom Kim Scientific Reports 6 (1), 20708-, 2016-02-05

...This feeder-free and xeno-free culture method using DAS-NG will facilitate the generation of clinical-grade hPSC.</jats:p>...

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Ayesh K. Seneviratne, Gillian I. Bell, Stephen E. Sherman, Tyler T. Cooper, David M. Putman, David A. Hess Stem Cells 34 (4), 873-887, 2016-01-19

...Here we demonstrate that prospectively purified UCB ALDHhi cells expand efficiently under serum-free, xeno-free conditions with minimal growth factor supplementation....

DOI PDF Web Site ほか2件 被引用文献1件

Alvaro Plaza Reyes, Sandra Petrus-Reurer, Liselotte Antonsson, Sonya Stenfelt, Hammurabi Bartuma, Sarita Panula, Theresa Mader, Iyadh Douagi, Helder André, Outi Hovatta, Fredrik Lanner, Anders Kvanta Stem Cell Reports 6 (1), 9-17, 2016-01

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Jieun Jung, Jong-Wan Kim, Ho-Jin Moon, Jin Young Hong, Jung Keun Hyun Stem Cells International 2016 1-12, 2016

...In this study, we selectively expanded stem cells from human dental pulp in an initial culture using NSC media under xeno- and serum-free conditions....

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松田 幸樹, 高橋 依子, 多々良 友博, 刈谷 龍昇, 岡田 誠治 サイトメトリーリサーチ 26 (1), 23-29, 2016

...In this study, we established non-irradiated GVHD mice model by xeno-transplantaion of human PBMC into BALB/c Rag-2/Jak3 double deficient (BALB/c R/J) mice....

DOI 医中誌

NAGAYA Masaki, WATANABE Masahito, KOBAYASHI Mirina, NAKANO Kazuaki, ARAI Yoshikazu, ASANO Yoshinori, TAKEISHI Toki, UMEKI Ikuma, FUKUDA Tooru, YASHIMA Sayaka, TAKAYANAGI Shuko, WATANABE Nobuyuki, ONODERA Masafumi, MATSUNARI Hitomi, UMEYAMA Kazuhiro, NAGASHIMA Hiroshi Journal of Reproduction and Development 62 (5), 511-520, 2016

...Cell or tissue transplantation studies using fluorescent markers should be conducted, wherein the xeno-antigenicity of the fluorescent proteins does not affect engraftment or graft survival....

DOI Web Site Web Site ほか2件 被引用文献1件 参考文献40件

Akon Higuchi, Shih-Hsuan Kao, Qing-Dong Ling, Yen-Ming Chen, Hsing-Fen Li, Abdullah A. Alarfaj, Murugan A. Munusamy, Kadarkarai Murugan, Shih-Chang Chang, Hsin-Chung Lee, Shih-Tien Hsu, S. Suresh Kumar, Akihiro Umezawa Scientific Reports 5 (1), 18136-, 2015-12-14

...substrates (30.4 kPa) tended to differentiate after five days of culture, whereas the hPSCs cultured on the optimal elastic substrates (25 kPa) maintained their pluripotency for over 20 passages under xeno-free...

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Alan Tin-Lun Lam, Jian Li, Allen Kuan-Liang Chen, William R. Birch, Shaul Reuveny, Steve Kah-Weng Oh BioResearch Open Access 4 (1), 242-257, 2015-12

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Ameneh Omidi, Iraj Ragerdi Kashani, Mohammad Akbari, Keywan Mortezaee, Soudabeh Ghasemi, Cordian Beyer, Adib Zendedel Biochemistry and Cell Biology 93 (6), 619-625, 2015-12

...<jats:p> An embryo has the capability to accept allo- or xeno-geneic cells, which probably makes it an ideal candidate for stem cell transplantation of various cerebral cortex abnormalities, such as cortical...

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Angelos Oikonomopoulos, Welmoed K. van Deen, Aida-Rae Manansala, Precious N. Lacey, Tamera A. Tomakili, Alyssa Ziman, Daniel W. Hommes Scientific Reports 5 (1), 16570-, 2015-11-13

...Human BMMSC and AdMSC were expanded in media supplemented with either human platelet lysates (HPL), serum-free media/xeno-free FDA-approved culture medium (SFM/XF), or fetal bovine serum (FBS) and the...

DOI PDF Web Site 被引用文献3件

Juan Wang, Jie Hao, Donghui Bai, Qi Gu, Weifang Han, Lei Wang, Yuanqing Tan, Xia Li, Ke Xue, Pencheng Han, Zhengxin Liu, Yundan Jia, Jun Wu, Lei Liu, Liu Wang, Wei Li, Zhonghua Liu, Qi Zhou Stem Cell Research & Therapy 6 (1), 223-, 2015-11-12

...induced by the Xeno reagents....

DOI PDF Web Site ほか1件 被引用文献2件

Siqin Wu, Jan Johansson, Outi Hovatta, Anna Rising Cellular and Molecular Life Sciences 73 (7), 1479-1488, 2015-10-01

DOI PDF Web Site ほか1件 被引用文献1件

M. Athanassiou-Papaefthymiou, P. Papagerakis, S. Papagerakis Journal of Dental Research 94 (11), 1591-1600, 2015-09-21

...In addition, we report the clonal expansion and isolation of human LGR5<jats:sup>+ve</jats:sup> cells from the hERM in xeno-free culture conditions....

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Per Bengtson, Bobby G. Ng, Jaak Jaeken, Gert Matthijs, Hudson H. Freeze, Erik A. Eklund Journal of Inherited Metabolic Disease 39 (1), 107-114, 2015-09-03

<jats:title>Abstract</jats:title><jats:p>ALG1‐CDG (formerly CDG‐Ik) is a subtype of congenital disorders of glycosylation (CDG) where the genetic defect disrupts the synthesis of the lipid‐linked …

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Dimitrios Xenos, David Grégoire, Stéphane Morel, Peter Grassl Journal of the Mechanics and Physics of Solids 82 48-60, 2015-09

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HM El-Damanhoury, M Gaintantzopoulou Operative Dentistry 40 (5), 480-491, 2015-09-01

...The materials tested were Adper Easy Bond, Clearfil S3 Bond, iBond, Optibond All-in-One, Xeno IV, and Adper Single Bond Plus as a control....

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C Sabatini, Z Wu Operative Dentistry 40 (5), 548-557, 2015-09-01

...Only MicroPrime B bonded with Xeno IV and iBond with no desensitizer demonstrated a significant reduction in SBS after three months (p=0.034 and p=0.002, respectively)....

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Tsuneo Takenaka, Tsutomu Inoue, Takashi Miyazaki, Matsuhiko Hayashi, Hiromichi Suzuki Journal of Bone and Mineral Research 31 (2), 455-462, 2015-08-19

<jats:title>ABSTRACT</jats:title> <jats:sec> <jats:title> </jats:title> <jats:p>Although fibroblast growth factor (FGF) 23 was recently identified …

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Neil H Riordan, Marialaura Madrigal, Jason Reneau, Kathya de Cupeiro, Natalia Jiménez, Sergio Ruiz, Nelsy Sanchez, Thomas E Ichim, Francisco Silva, Amit N Patel Journal of Translational Medicine 13 (1), 232-, 2015-07-17

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Yoon Lee, So‐Youn An, Yoon‐Jung Park, Frank H. Yu, Joo‐Cheol Park, Deog‐Gyu Seo Scanning 38 (1), 36-42, 2015-07-16

...Cells from an immortalized mouse odontoblast cell line (MDPC‐23) were cultured with six different dental adhesive systems (diluted to concentrations of 0.5% for 4 h): Adper Easy Bond (EB), Xeno V (XV),...

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Hwajung Kim, Wayne J. Hawthorne, Hee Jung Kang, Yoo Jin Lee, Jong‐Ik Hwang, Sunghoon Hurh, Han Ro, Jong Cheol Jeong, Bumrae Cho, Jaeseok Yang, Curie Ahn Xenotransplantation 22 (4), 260-272, 2015-07

...Clearly then human <jats:styled-content style="fixed-case">TBM</jats:styled-content> has complement regulatory effects as well as anticoagulant effects in xeno‐immune response, and it is a promising target...

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Jeanette Beers, Kaari L. Linask, Jane A. Chen, Lauren I. Siniscalchi, Yongshun Lin, Wei Zheng, Mahendra Rao, Guokai Chen Scientific Reports 5 (1), 11319-, 2015-06-11

...Factors limiting the adoption of iPSC technology include the cost of developing lines and the time period that it takes to characterize and bank them, particularly when integration free, feeder free and Xeno-free...

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