検索結果 65 件

青木 信樹, 薄田 芳丸, 石塚 康夫, 若林 信人, 林 静一, 本間 康夫, 北村 亘子 日本化学療法学会雑誌 47 (Supplement1), 204-208, 1999

The pharmacokinetics of pazufloxacin mesilate (PZFX mesilate), a newly developed quinolone antimicrobial agent, were investigated in the elderly. The seven patients (71-88 years old) were classified …

DOI 医中誌 被引用文献2件 参考文献6件

青木 信樹, 甲田 豊, 高澤 哲也, 吉川 博子, 若林 伸人, 林 静一, 新田 功, 小浦方 洋一, 本間 康夫, 北村 宣子, 渡辺 京子 日本化学療法学会雑誌 44 (Supplement1), 295-304, 1996

We studied NM441, a new oral quinolone antimicrobial agent, and obtained the following results.<BR>1) Serum and urinary levels of NM394 were determined after oral administration of NM441 (200mg) to …

DOI 医中誌 被引用文献2件 参考文献5件

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 小浦方 洋一, 新田 功, 本間 康夫, 北村 亘子 日本化学療法学会雑誌 43 (Supplement2), 256-265, 1995

We studied a newly developed oral quinolone antimicrobial agent, pazufloxacin (PZFX), and obtained the following results<BR>1) Serum and urinary levels of PZFX were determined after oral …

DOI 医中誌 参考文献3件

青木 信樹, 薄田 芳丸, 若林 信人, 林 静一, 渡辺 京子, 本間 康夫 日本化学療法学会雑誌 43 (Supplement4), 52-60, 1995

We studied a newly developed cephem antibiotic, cefluprenam (CFLP), and obtained the following results.<BR>1) Clinical pharmacological studies of CFLP were conducted in 12 patients aged 70 to 97 …

DOI 医中誌 参考文献4件

青木 信樹, 薄田 芳丸, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 42 (Supplement1), 712-715, 1994

SY5555, a new oral penem, was administered to 13 patients with respiratory tract infection to evaluate its clinical efficacy. The patients' ages ranged from 21 to 77 years; 9 were male and 4 were …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 新田 功, 小浦方 洋一, 本間 康夫, 北村 宣子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 42 (Supplement4), 350-364, 1994

We studied a newly developed carbapenem, biapenem (BIPM), and obtained the following results.<BR>1) Clinical pharmacological studies of BIPM were conducted in 10 patients with renal dysfunction. The …

DOI

青木 信樹, 薄田 芳丸, 吉川 博子, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 新田 功, 本間 康夫, 北村 亘子 ＣＨＥＭＯＴＨＥＲＡＰＹ 42 (Supplement3), 172-183, 1994

We studied the pharmacokinetics of FK037, a newly developed cephalosporin antibiotic, in 12 patients with renal dysfunction.<BR>The drug was injected intravenously at a dose of 0.5g by drip infusion …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 小浦方 洋一, 新田 功, 本間 康夫, 北村 亘子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 42 (Supplement2), 401-409, 1994

We studied a newly developed β-lactamase inhibitor combined with penicillin, tazobactam/piperacillin (TAZ/PIPC), and obtained the following results.<BR>1) Clinical pharmacological studies of …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 The Japanese Journal of Antibiotics 46 (8), 637-646, 1993

腎機能障害患者における新規セフェム系抗生物質DQ-2556の体内動態について検討した。本剤1.0g静注後, 血中濃度の最大値は腎機能障害の程度にかかわらず投与5分後にみられ, その値に大きな差はみられなかった。一方, 血中濃度低下は腎機能障害が重度になるに従い緩除になり, 重度障害例, 特に血液透析導入例において著明であつた。すなわち血中濃度半減期(β相)は, 軽度障害例 …

DOI PubMed 医中誌

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 新田 功, 小浦方 洋一, 渡辺 京子, 本間 康夫, 北村 亘子 The Japanese Journal of Antibiotics 46 (12), 1063-1074, 1993

種々の腎機能障害患者において, 新経口セフェム剤S-1108の体内動態について検討した。本剤150mgを朝食後30分に経口投与した際の血中濃度のピーク値は投与3～6時間後に得られ, 腎機能低下が高度になるにつれ高い傾向を示し, 血中濃度の低下は, 腎機能障害が重度になるに従い緩徐となり, 特に血液透析導入例において著明であった。すなわち血中濃度半減期 (β相) は軽度障害例 …

DOI PubMed 医中誌 被引用文献1件

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 40 (Supplement1), 366-382, 1992

We studied a newly developed carbapenem, meropenem (MEPM), and obtained the following results.<BR>1) Clinical, pharmacological studies of MEPM were conducted in 14 patients with renal dysfunction. …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 高澤 哲也, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 40 (Supplement2), 371-381, 1992

We studied ME 1207 a new oral cephem, and obtained the following results.<BR>1) Serum and urinary levels of ME 1206 were determined after oral administration of ME 1207 200mg to 10 patients with …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 関根 理, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 40 (Supplement4), 312-318, 1992

We studied a newly developed cephalosporin, cefclidin (CFCL), and obtained the following results.<BR>1) The pharmacokinetics of cefclidin were evaluated in 6 patients on continuous ambulatory …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 The Japanese Journal of Antibiotics 45 (5), 530-538, 1992

ニューキノロン系抗菌剤 Levofloxacin (LVFX, DR-3355) について, 高齢者における基礎的・臨床的検討を行い, 以下の成績を得た。<BR>1. 体内動態<BR>種々の腎機能障害を有する高齢者にLVFX 100mgを朝食後30分に経口投与した際の血中・尿中濃度を測定した。腎機能障害の程度により軽度 (I), 中等度 (II), 高度 (III) …

DOI PubMed

青木 信樹, 薄田 芳丸, 甲田 豊, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 39 (Supplement1), 129-135, 1991

We studied a new cephalosporin antibiotic, cefpirome (CPR), and obtained the following results.<BR>1. Serum and urine levels of CPR were determined after intravenous drip infusion of 1.0 g to six …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 39 (Supplement4), 261-271, 1991

We studied a newly developed oral quinolone antimicrobial agent, sparfloxacin (SPFX), and obtained the following results.<BR>1) Serum and sputum levels of SPFX were determined after oral …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 高沢 哲也, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 39 (Supplement3), 372-384, 1991

We studied a newly developed carbapenem, panipenem/betamipron (PAPM/BP), and obtained the following results.<BR>1) Clinical pharmacological studies of PAPM/BP were conducted in 16 patients with …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 関根 理, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 39 (Supplement2), 420-424, 1991

Cefepime was used to treat 20 patients with respiratory tract infection, 1 with urinary tract infection and 1 with sepsis, meningitis, orbital cellulitis and multiple pulmonary abscesses caused by …

DOI

青木 信樹, 薄田 芳丸, 甲田 豊, 関根 理, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 38 (Supplement1), 133-142, 1990

We studied a new oral cephem, cefetamet pivoxil (CEMT-PI), and obtained the following results.<BR>1) Serum and urine levels of cefetamet (CEMT) were determined after oral administration of CEMT-PI …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 37 (Supplement2), 451-457, 1989

We used a new oral cephem antibiotic, cefdinir (CFDN), to treat 17 patients with respiratory and 1 with urinary tract infection, and to evaluate its efficacy and safety. The study was carried out …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 甲田 豊, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 37 (Supplement1), 172-177, 1989

We used a new oral cephem antibiotic, 7432-S, to treat 16 patients with respiratory tract infection, and to evaluate its efficacy and safety. The study was carried out from April to July 1986. The …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 37 (Supplement3), 309-313, 1989

We used a new oral cephem antibiotic, BMY-28100, to treat 8 patients with respiratory tract infections, and to evaluate its efficacy and safety. The patients consisted of 3 males and 5 females, aged …

DOI

青木 信樹, 宮崎 滋, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 36 (Supplement5), 427-433, 1988

We studied a new antibiotic, THR-221, in our clinic, and obtained the following results.<BR>1. Clinical pharmacological studies of THR-221 were conducted in 6 patients with renal dysfunction. The …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 36 (Supplement1), 470-477, 1988

We used a new oral cephem antibiotic, CS-807, to treat 26 patients with respiratory and 3 with urinary tract infections, and to evaluate its efficacy and safety. The study was carried out from …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 36 (Supplement2-Clinical), 620-624, 1988

NY-198 was administered orally to 9 patients with respiratory and 2 with urinary tract infection, and its efficacy and safety were studied. The study was carried out from September to December, …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 36 (Supplement6), 345-349, 1988

A new oral cephem antibiotic, cefotiam hexetil (CTM-HE), was given to 10 patients with respiratory and 1 with urinary tract infection, and its efficacy and safety were studied. The study was carried …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 36 (Supplement9-Clinical), 532-542, 1988

We used T-3262 a newly developed quinolone antibacterial agent, to treat 29 patients with respiratory and 2 with urinary tract infection, and studied its efficacy and safety. The study was carried …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 山作 房之輔, 鈴木 康稔, 若林 伸人, 林 静一, 新田 功, 本間 千鶴子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 36 (Supplement4), 256-260, 1988

A new oral macrolide antibiotic, RU 28965, was used to treat 21 patients with respiratory tract infection, and its efficacy and safety were studied.<BR>The study was carried out from March 1986 to …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 34 (Supplement2), 414-426, 1986

A new oral cephem antibiotic T-2588 was used to treat 41 patients with respiratory tract infection, 5 with urinary tract infection and 1 with fever unknown origin, and its safety and efficacy were …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 34 (Supplement4), 421-430, 1986

Serum and/or urine levels of ticarcillin (TIPC) and clavulanic acid (CVA) were determined during treatment 6 patients with BRL 28500, a formulation of clavulanic acid (CVA) and ticarcillin …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 34 (Supplement3), 203-211, 1986

L-105, a new broad-spectrum injectable cephalosporin, was used to treat 24 patients with respiratory tract infection, and its efficacy and safety were studied. The study was carried out from July, …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 34 (Supplement5), 457-465, 1986

A new oral cephem antibiotic, cefuroxime axetil (CXM-AX) was administered to total 28 patients consisting of 26 with respiratory tract infections and 2 with urinary tract infections, and its …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 清水 武昭, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 33 (Supplement2), 203-208, 1985

Bile and serum levels of sultamicillin were determined after oral administration of 375 mg sultamicillin to 2 patients with obstructive jaundice, and urinary recovery rate was determined in one …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 清水 武昭, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 33 (Supplement1), 300-304, 1985

Azthreonam was studied in 12 patients: 8 with respiratory tract infections and 4 with urinary tract infections, and the following results were obtained.<BR>Azthreonam was used intravenously at a …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 33 (Supplement6), 357-366, 1985

Cefixime (CFIX) was administered to a total of 35 patients: 34 with respiratory tract infections, 1 with urinary tract infection. It was given orally twice a day at a dose of 200mg to the patients …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 33 (Supplement7), 253-262, 1985

BAY o 9867 was administered to 43 patients: 40 respiratory tract infection, 3 urinary tract infection.It was given orally at a dose of 600 mg/day to the patients with respiratory tract infection and …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 33 (Supplement4), 433-441, 1985

Imipenem/Cilastatin sodium (MK-0787/MK-0791) was administered intravenously, at a dose of 1.0g (0.5g as MK-0787) by drip infusion for 30 minutes, into 2 patients with renal insufficiency, and its …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 清水 武昭, 若林 伸人, 林 静一, 新田 功, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 32 (Supplement7), 364-370, 1984

A new antibiotic, ceftriaxone (CTRX, Ro 13-9904), has been studied in the clinica, resulting in the following findings.<BR>1) CTRX was administered to 21 patients: 16 with respiratory tract …

DOI 医中誌

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 新田 功, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 32 (Supplement1), 209-213, 1984

DL-8280, 200 to 900 mg/day, was administered orally to 20 patients with respiratory tract infection. Clinical effects were excellent in 2 patients, good in 12, fair in 2, and undetermined in 4, thus …

DOI

関根 理, 薄田 芳丸, 青木 信樹, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 32 (Supplement6), 253-256, 1984

TMS-19-Q was administered orally to 13 patients with respiratory tract infection, resulting in the clinical responses as excellent in 1, good in 7 and fair in 5. No adverse reaction was observed. …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 田中 富美子, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 32 (Supplement8), 250-256, 1984

Lenampicillin (KBT-1585), 1, 000 mg/day, was administered orally to 22 patients with respiratory tract infections, and the following results were obtained.<BR>Clinical response of KBT-1585 was …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 清水 武昭, 若林 伸人, 林 静一, 新田 功, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 32 (Supplement3), 490-497, 1984

Clinical studies on AT-2266, a newly synthesized antimicrobial compound, were carried out in this clinic and the following results were obtained.<BR>1. AT-2266 was administered to a total of 30 …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 清水 武昭, 若林 伸人, 林 静一, 新田 功, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 32 (Supplement5), 222-228, 1984

A new antibiotic MT-141 has been studied in the clinic, resulting the following findings.<BR>1. MT-141 was administered to 21 patients: 18 with respiratory tract infection, 1 with urinary tract …

DOI

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 31 (Supplement1), 334-342, 1983

Cefpiramide (CPM, SM-1652) has been studied in clinic, and the following results were obtained.<BR>1) Cefpiramide was injected 1.5g iv twice a day for 2.5 days into the patient (A) with normal renal …

DOI Web Site 医中誌

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 若林 伸人, 林 静一, 新田 功, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 31 (Supplement3), 353-359, 1983

Ceftaziclime, (CAZ, SN401), a new broad-spectrum injectable cephalosporin, was studied in 21 patients: 20 with respiratory tract infections and 1 with urinary tract infection, and the following …

DOI Web Site 医中誌

中川 圭一, 小山 優, 斉藤 玲, 富沢 磨須美, 岡本 正敏, 木下 与四男, 武部 和夫, 熊坂 義裕, 小坂 志朗, 中村 光男, 今村 憲市, 町田 光司, 佐々木 和雄, 成田 祥耕, 田村 豊一, 高橋 清仁, 小林 正資, 馬場 恒春, 柾木 尚義, 林 泉, 玉木 重, 勝 正孝, 滝塚 久志, 黒木 達郎, 北本 治, 小林 宏行, 藤森 一平, 小花 光夫, 小林 芳夫, 三井 健司, 関根 理, 薄田 芳丸, 小柳 武久, 張 達聰, 若林 伸人, 林 静一, 渡辺 京子, 高頭 正長, 大山 馨, 清水 隆作, 栗村 統, 中田 将風, 桑島 恵一, 中西 幸三, 村上 光, 今井 淳子, 内田 英男, 田原 實, 田中 恒男, 竹内 文生, 出口 浩一 感染症学雑誌 56 (11), 982-1002, 1982

われわれは新しく開発されたマクロライド系抗生物質9, 3′′-di-0-acetyl midecamycin (MOM) につき急性扁桃炎を対象とし, 対照薬としてJosamycin (JM) を使用した二重盲検試験により両薬剤の薬効を比較検討する機会を得た.<BR>1日投与量としてMoM を 600 mg, JM を 1,200 mg経口投与し, 服用期間は7日間とした. …

DOI Web Site PubMed ほか1件

薄田 芳丸, 田尻 正記, 湯浅 保子, 中村 享道, 関根 理, 青木 信樹, 林 静一, 渡辺 京子, 橋本 俊広, 服部 信之 ＣＨＥＭＯＴＨＥＲＡＰＹ 30 (Supplement2), 91-97, 1982

The <I>in vivo</I> dynamics of BRL25000 were investigated following a single oral administration of 375 mg [2 tablets of 187. 5 mg of BRL25000 containing 125 mg (pfa) amoxicillin trihydrate and …

DOI Web Site 医中誌 被引用文献1件

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 塚田 芳久, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 29 (Supplement1), 433-440, 1981

A new antibiotic cefmenoxime (CMX, SCE-1365) has been studied in the clinic, and the following results were obtained.<BR>1. Cefmenoxime was administered to 21 patients; 16 respiratory tract …

DOI Web Site 医中誌

青木 信樹, 関根 理, 薄田 芳丸, 湯浅 保子, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 28 (Supplement7), 361-369, 1980

A new antibiotic 6059-S has been studied in the clinic, and the following results were obtained.<BR>1. 6059-S was injected intravenously at a dose of 1 g into the 12 patients with various renal …

DOI Web Site 医中誌

薄田 芳丸, 関根 理, 青木 信樹, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子, 重栖 幹夫, 笠井 一弘 ＣＨＥＭＯＴＨＥＲＡＰＹ 28 (Supplement1), 293-303, 1980

1) Clinical pharmacological studies of cefotaxime (HR 756, CTX) were conducted in patients with various renal function. The results are shown in Tables 1, 2 and 3, and Fig. 1, 2, 3, 4, 5 and 6. …

DOI Web Site 医中誌

薄田 芳丸, 関根 理, 青木 信樹, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 28 (Supplement2), 122-126, 1980

1) Clinical pharmacological studies were conducted with cefadroxil in the patients of impaired renal function. Cefadroxil was administered orally at a single 500 mg dose, and its concentration in …

DOI Web Site 医中誌

青木 信樹, 関根 理, 薄田 芳丸, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 28 (Supplement6), 341-353, 1980

Cefoperazone (CPZ, T-1551) has been studied in clinic, and the following results were obtained.<BR>1) CPZ was injected intravenously at a dose of 1, 000 mg into the 5 patients with various renal …

DOI Web Site 医中誌

関根 理, 薄田 芳丸, 青木 信樹, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 28 (Supplement3), 233-236, 1980

After the oral administration of 0.5g Cefroxadine (CGP-9000, CXD) to patients with various renal failures, the serum levels of this antibiotic were measured. As the degree of renal impairment …

DOI Web Site 医中誌

関根 理, 薄田 芳丸, 青木 信樹, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 27 (Supplement7), 205-208, 1979

Cefaclor was administered orally to 15 patients with respiratory tract infection and to 5 patients with urinary tract infection.<BR>The clinical effectiveness was good in 11, fair in 3, and poor in …

DOI Web Site 医中誌

青木 信樹, 関根 理, 薄田 芳丸, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 27 (Supplement6), 323-327, 1979

Cefuroxime has been studied clinically, and the following results were obtained.<BR>1. Cefuroxime was administered to 23 patients: 20 respiratory tract infection, 1 pyothorax, and 2 urinary trct …

DOI Web Site 医中誌

薄田 芳丸, 関根 理, 青木 信樹, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 27 (Supplement4), 84-87, 1979

Bacampicillin was used in 14 cases (acute bronchitis 4 cases, acute tonsillitis 3 cases, emphysema 3 cases, bronchiectasis one case, lung abscess one case, chronic bronchitis? one case and fever of …

DOI Web Site 医中誌

青木 信樹, 関根 理, 薄田 芳丸, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 27 (Supplement1), 104-108, 1979

Mezlocillin has been studied clinically, and the following results were obtained.<BR>1. Mezlocillin was injected at a dose of 2g to the patients with various renal function, and the blood …

DOI Web Site 医中誌

関根 理, 薄田 芳丸, 青木 信樹, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 27 (Supplement2), 187-192, 1979

1. After 0.5g of Cefsulodin (SCE-129, CFS) was injected intravenously into the patients with renal failure, serum concentrations were measured.<BR>The decrease of CFS levels in the serum slightly …

DOI Web Site 医中誌

関根 理, 薄田 芳丸, 青木 信樹, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 27 (Supplement5), 161-166, 1979

1. Concentrations of cefamandole in urine were estimated in the patients with renal failure at various stages after 1 g of cefamandole was injected intravenously. The more severe were the degree of …

DOI Web Site 医中誌

薄田 芳丸, 関根 理, 青木 信樹, 清水 武昭, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 27 (Supplement3), 297-303, 1979

1) Clinical pharmacological studies of cefotiam (SCE-963) were conducted in patients with various renal function. The serum concentrations of cefotiam in the patients 1, 3, 5, 8 and 24 hours after …

DOI Web Site 医中誌

関根 理, 薄田 芳丸, 青木 信樹, 若林 伸人, 林 静一, 渡辺 享子 ＣＨＥＭＯＴＨＥＲＡＰＹ 26 (Supplement2), 295-300, 1978

1) The concentration in blood of a new synthetic penicillin PC-904 was measured in patients with impaired renal function. The results indicated that the blood level of the penicillin was lowered …

DOI Web Site 医中誌

関根 理, 薄田 芳丸, 青木 信樹, 若林 伸人, 林 静一, 武田 元, 庭山 昌俊, 蒲沢 知子 ＣＨＥＭＯＴＨＥＲＡＰＹ 26 (Supplement1), 267-271, 1978

1. Cefoxitin was administered to 20 patients ; 16 respiratory tract infections, 2 urinary tract infections and 2 sepsis (suspected).<BR>2. Cefoxitin was given intravenously at a daily dose of 2 to 4 …

DOI Web Site 医中誌

薄田 芳丸, 関根 理, 青木 信樹, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 25 (9), 2589-2594, 1977

1) Clinical pharmacological studies of ticarcillin were conducted in patients with impaired renal function.The ticarcillin concentrations in the serum of patients 1, 2, 4, 6, 24 hours after an …

DOI Web Site 医中誌

関根 理, 薄田 芳丸, 青木 信樹, 若林 伸人, 林 静一, 渡辺 京子 ＣＨＥＭＯＴＨＥＲＡＰＹ 25 (7), 1952-1957, 1977

KW-1062 is a new aminoglycoside antibiotic with potent antimicrobial activity against gram-negative bacteria.<BR>1. After a single intramusclar injection of 40 mg of KW-1062 to patients with …

DOI Web Site 医中誌

近藤 金助, 林 靜一, 森重 新一 日本農芸化学会誌 15 (8), 727-736, 1939

(1) 所謂大豆粕より稀薄なアルカリ溶液を用ゐて抽出調製した蛋白を40%の尿素液に溶解して然る後,此の蛋白尿素水溶液に純酒精を滴加して分別を試みた.<br> (2) 其の結果として酒精低濃度にて雪出する(A),酒精高濃度にて雪出する(B)及び酒精が高濃度に達しても特定のpH價を與へなければ雪出しない所の(C)の3部に分別したが(A)を更に(a)及び(b)に分別したのである.<br> (3) …

DOI