検索結果 23 件

Azusa Yamato, Hidekazu Nagano, Yue Gao, Tatsuma Matsuda, Naoko Hashimoto, Akitoshi Nakayama, Kazuyuki Yamagata, Masataka Yokoyama, Yingbo Gong, Xiaoyan Shi, Siti Nurul Zhahara, Takashi Kono, Yuki Taki, Naoto Furuki, Motoi Nishimura, Kentaro Horiguchi, Yasuo Iwadate, Masaki Fukuyo, Bahityar Rahmutulla, Atsushi Kaneda, Yoshinori Hasegawa, Yusuke Kawashima, Osamu Ohara, Tetsuo Ishikawa, Eiryo Kawakami, Yasuhiro Nakamura, Naoko Inoshita, Shozo Yamada, Noriaki Fukuhara, Hiroshi Nishioka, Tomoaki Tanaka Communications Biology 5 (1), 2022-11-27

...Targeted capture sequencing and copy number analysis of 36 genes and nontargeted proteomics analysis were performed on fresh-frozen samples from 121 sporadic GHomas/somatotroph PitNETs....

DOI PDF Web Site 被引用文献1件 参考文献39件

Watanabe Daisuke, Yagasaki Hideaki, Kojika Satoru, Ogiwara Masakazu, Kinouchi Hiroyuki, Nakane Takaya, Inukai Takeshi Endocrine Journal 66 (5), 403-408, 2019

...<p>GH-secreting pituitary adenomas (GHomas) are rare in the pediatric population....

DOI Web Site PubMed ほか1件 被引用文献1件 参考文献26件

Tetsuhiko Sato, Hirotaka Komaba, Tetsuya Nagatani, Tadashi Watanabe, Yugo Kishida, Masafumi Fukagawa Journal of the Endocrine Society 3 (1), 52-61, 2018-11-14

...), and 14 with non–GH-producing pituitary adenomas (non-GHomas), before and after endoscopic transsphenoidal surgery (eTSS)....

DOI PDF 被引用文献1件

中島 孝, 岩佐 将充, 金森 寛充, 牛越 博昭, 川崎 雅規, 西垣 和彦, 小椋 弘樹, 石田 成吏洋, 島袋 勝也, 宮崎 龍彦, 竹村 博文, 湊口 信也 心臓 48 (7), 774-780, 2016

...GHomaに対する下垂体腫瘍摘出術の既往およびPPNADがある. 今のところ心臓腫瘍は認めていない.</p><p> 2症例の4腫瘍はいずれも病理学的には粘液腫であった. CNCは遺伝性疾患であり家族内発症し, 高率に心臓腫瘍を合併する. またCNCに合併する心臓腫瘍は再発率が高い. 心臓腫瘍未発症の家族も含め, 永年の注意深い経過観察が必要である.</p>...

DOI 医中誌

富永 篤, 木下 康之, 栗栖 薫 Japanese Journal of Neurosurgery 25 (8), 637-645, 2016

<p> 下垂体腫瘍, 特に機能性下垂体腺腫およびincidentalomaに対する手術適応について述べる.</p><p> 下垂体腺腫に対する治療法には手術療法, 薬物療法, 放射線療法があるが, 特に機能性下垂体腺腫では手術療法と薬物療法の選択が重要である.</p><p> 機能性腺腫のうち成長ホルモン産生腺腫, adrenocorticotropin stimulating hormone …

DOI Web Site 医中誌 参考文献26件

Edo Naoki, Morita Koji, Suzuki Hisanori, Takeshita Akira, Miyakawa Megumi, Fukuhara Noriaki, Nishioka Hiroshi, Yamada Shozo, Takeuchi Yasuhiro Endocrine Journal 63 (5), 469-477, 2016

...The GH nadir at the first postoperative year evaluation may be insufficient in patients with normalized IGF-1 with low insulin resistance immediately following complete resection of GHoma....

DOI Web Site PubMed 被引用文献1件 参考文献37件

Yuji Tani, Shozo Yamada, Naoko Inoshita, Yukio Hirata, Masayoshi Shichiri Scientific Reports 5 (1), 10878-, 2015-06-03

...Positive PRR immunoreactivity was detected more often in surgically resected, growth hormone-producing adenomas (GHomas) than in nonfunctional pituitary adenomas....

DOI PDF Web Site 被引用文献7件 参考文献43件

Kenta Koketsu, Daizo Yoshida, Kyongsong Kim, Yudo Ishii, Shigeyuki Tahara, Akira Teramoto, Akio Morita International Journal of Endocrinology 2015 1-7, 2015

...Double fluorescence immunohistochemistry of Gremlin and CD34 was performed in pituitary adenoma tissues obtained during transsphenoidal surgery in 45 cases (7 PRLoma, 17 GHoma, 2 ACTHoma, and 2 TSHoma)...

DOI PDF XML 参考文献36件

Federico Gatto, Richard Feelders, Rob van der Pas, Johan M. Kros, Fadime Dogan, Peter M. van Koetsveld, Aart-Jan van der Lelij, Sebastian J. C. M. M. Neggers, Francesco Minuto, Wouter de Herder, Steven W. J. Lamberts, Diego Ferone, Leo J. Hofland Endocrinology 154 (12), 4715-4725, 2013-12-01

...However, its expression was significantly lower in GHomas and PRLomas, compared with NFPAs (P &lt; .01). GRK2 expression was higher in PRLomas and NFPAs compared with GHomas (P &lt; .05)....

DOI PDF 被引用文献2件

TANAKA Toshihide, KATO Naoki, AOKI Ken, WATANABE Mitsuyoshi, ARAI Takao, HASEGAWA Yuzuru, ABE Toshiaki Neurologia medico-chirurgica 53 (10), 707-711, 2013

This report describes a rare case of a patient with growth hormone (GH)-secreting pituitary adenoma with malignant transformation resulting in multiple metastases to the dura mater of the cerebral …

DOI Web Site PubMed ほか1件 参考文献43件

D Dworakowska, E Wlodek, C A Leontiou, S Igreja, M Cakir, M Teng, N Prodromou, M I Góth, S Grozinsky-Glasberg, M Gueorguiev, B Kola, M Korbonits, A B Grossman Endocrine-Related Cancer 16 (4), 1329-1338, 2009-12

...We studied tissue from 16 non-functioning pituitary adenomas (NFPAs), six GH-omas, six prolactinomas and six ACTH-omas, all collected at transsphenoidal surgery; 16 normal autopsy pituitaries were used...

DOI XML XML 被引用文献5件

Alexander Gorshtein, Hadara Rubinfeld, Efrat Kendler, Marily Theodoropoulou, Vesna Cerovac, Günter K Stalla, Zvi R Cohen, Moshe Hadani, Ilan Shimon Endocrine-Related Cancer 16 (3), 1017-1027, 2009-09

...anti-proliferative efficacy of the mTOR inhibitor, rapamycin, and its orally bioavailable analog RAD001 on the GH-secreting pituitary tumor GH3 and MtT/S cells and in human GH-secreting pituitary adenomas (GH-omas...

DOI XML XML 被引用文献1件

Osamura Robert Y., Egashira Noboru, Kajiya Hanako, Takei Mao, Tobita Maya, Miyakoshi Takashi, Inomoto Chie, Takekoshi Susumu, Teramoto Akira Ａｃｔａ　Ｈｉｓｔｏｃｈｅｍｉｃａ　ｅｔ　Ｃｙｔｏｃｈｅｍｉｃａ 42 (4), 95-104, 2009

...Growth hormone (GH)-producing adenomas (GHomas) are one of the most frequently-occurring pituitary adenomas....

DOI Web Site PubMed ほか1件 被引用文献5件 参考文献27件

Federica Barbieri, Adriana Bajetto, Ralf Stumm, Alessandra Pattarozzi, Carola Porcile, Gianluigi Zona, Alessandra Dorcaratto, Jean-Louis Ravetti, Francesco Minuto, Renato Spaziante, Gennaro Schettini, Diego Ferone, Tullio Florio Clinical Cancer Research 14 (16), 5022-5032, 2008-08-12

...identified in 63% and 78% of GHomas and NFPAs, respectively....

DOI PDF 被引用文献6件

A. Lania, M. Filopanti, S. Corbetta, M. Losa, E. Ballaré, P. Beck-Peccoz, A. Spada The Journal of Clinical Endocrinology & Metabolism 88 (4), 1692-1696, 2003-04-01

...Increasing cAMP by forskolin caused a protein kinase A-dependent increase of ERK activity (287 ± 37%) in GH-omas and had no effect in NFPA....

DOI PDF 被引用文献1件

ONO, Hideko, MORII, Ken, TAMURA, Tetsuro, TANAKA, Ryuichi Acta medica et biologica 51 (1), 25-30, 2003-03

...Methods: ISH and immunohistochemistry (IHC) were performed on serial frozen sections of three normal pituitary glands and tumors (10 GH-omas, 5 PRL-omas, 2 ACTH-omas, 10 nonfunctioning adenomas, 3 craniopharyngiomas...

機関リポジトリ HANDLE 医中誌

池田 輝雄, 郷間 雅之 獣医臨床皮膚科 8 (3), 23-32, 2002

本稿ではこれまで報告されているプロトテカ属およびプロトテカ症についての知見を概説する。プロトテカ属は，緑藻類に属するが色素を持たない腐生性の病原体であり，自然界に常在し，犬，猫，牛，人をはじめ広範囲の動物にプロトテカ症を引き起こす。<i>P. zopfii</i>および<i>P. wickerhamii</i>の2藻種がプロトテカ症の原因病原体であると報告されている。犬，牛，人のプロトテカ症は重…

DOI 医中誌 参考文献47件

IUCHI TOSHIHIKO, SAEKI NAOKATSU, UCHINO YOSHIO, HIGUCHI YOSHINORI, TATSUNO ICHIRO, NAKAMURA SUSUMU, YASUDA TOSHIYUKI, YAMAURA AKIRA Endocrine Journal 47 (SupplMarch), S77-S79, 2000

...We investigated the relation among tumor proliferative potential, tumor volume and invasion of GHomas to CS. <i>Materials & Methods</i> 15 patients with GHoma aged 20-59 years were enrolled....

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春名 眞一, 深見 雅也, 森山 寛, 神尾 正己 頭頸部外科 8 (1), 69-73, 1998

Pituitary tumor of 11 patients were excised via the endonasal-transsphenoidal approach. Their age ranged from 21 to 64 years, and the disease was non-functional in 4 cases, GHoma in 4, PRLoma in 2 …

DOI 被引用文献1件

山田 良雄, 矢吹 駿一, 郷間 光安 日本作物学会紀事 67 (3), 407-409, 1998

The wastewater from seed disinfecting, which precedes to the raising of rice seedlings, has a problem in terms of environmental pollution. The authors therefore examined a way of management to spray …

DOI Web Site

山田 良雄, 矢吹 駿一, 郷間 光安 日本作物学会関東支部会報 11 (0), 16-17, 1996

水稲の共同育苗を中心として、種子消毒の廃液処理について、河川への汚染を中心に問題化され始めている。特別な処理施設や機械を必要とせず、現在使用している機械等を活用し、安全・簡易で費用がかからない、廃液の利用(処理法)について報告する。

DOI

鬼頭 晃, 吉田 純, 景山 直樹 Neurological Surgery 脳神経外科 15 (7), 797-803, 1987-07-10

DOI 医中誌

恩田 清, 田中 隆一, 村上 直人, 鈴木 康夫, 山崎 一徳 Neurologia medico-chirurgica 26 (12), 937-944, 1986

The cytotoxic action of 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) is considered to be mainly the result of alkylation of deoxyribonucleic acid …

DOI Web Site PubMed ほか1件