Lipid modification of proteins : a practical approach
著者
書誌事項
Lipid modification of proteins : a practical approach
（The practical approach series）
IRL Press at Oxford University, c1992
- : pbk
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注記
Includes bibliographical references and index
内容説明・目次
- 巻冊次
-
: pbk ISBN 9780199632732
内容説明
Recent developments have shown that proteins can undergo a diverse range of modifications by lipid which can dramatically effect their structural and functional properties. These modifications include acylation, isoprenylation, and the attachment of glycolipid. Lipid modifications of proteins play important roles in cellular signalling, protein targeting and cellular growth and differentiation - the enzymes which catalyse these reactions are alreadt being seen as
novel therapeutic targets. The biochemical, cell biological, and molecular biological techniques being used in this rapidly expanding field are becoming increasingly sophisticated.
Lipid Modification of Proteins: A Practical Approach is a unique guide to the latest methods in use, written by the acknowledged experts in the field. Detailed protocols are provided for all the key techniques, and the relevant background material is included. This book will be an essential manual for a wide range of scientists studying the modification of protein by lipids, including membrane and protein biochemists, cell biologists, immunologists, bacteriologists, parasitologists,
and virologists.
目次
- A. J. Turner: The diversity of lipid modifications
- R. A. J. McIlhinney: Labelling of cell proteins with radioactive fatty acids and methods for studying palmitolyacyl transferase
- D. A. Rudnick, R J. Duronio, & J. I. Gordon: Methods for studying myristoyl-CoA: protein N-myristoyltransferase
- A. Aitken: Structure determination of acylated proteins
- N. M. Hooper: Identification of a glycosyl-phosphatidylinositol anchor of membrane proteins
- M. G. Low: Phospholipases that degrade the glycosyl-phosphatidyl inositol anchor of membr4ane proteins
- M. C. Field & A. K menon: Biosynthesis of flycosyl-phosphatidylinositol membrane protein anchors
- M. A. J. Ferguson: Chemical and enzymic analysis of glycosyl-phosphatidylinositol anchors
- M. H. Gelb, C. C. Farnsworth, & J. A. Glomset: Structural analysis of prenylated proteins
- S. Hayashi & H. C. Wu: Identification and characterization of lipid-modified proteins in bacteria.
- 巻冊次
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ISBN 9780199632749
内容説明
Recent developments have shown that proteins can undergo a diverse range of modifications by lipid which can dramatically effect their structural and functional properties. This book provides a unique guide to the latest methods in use, written by acknowledged experts in the field
目次
- The diversity of lipid moodifications of proteins, Anthony J.Turner
- Labelling of cell proteins with radioactive fatty acids and methods for studying malmitoyl-acyl transferase, A.J,McIlhinney
- Methods for studying myristoyl-CoA - protein N-myriostoyltransferase, David A.Rudnick, Robert J.Durino, Jeffery I.Gordon
- structure determination of acylated proteins, Alastair Aitken
- identification of a glycosyl-phosphatidylinositol anchor on membrane proteins, Nigel M.Hooper
- phospholipases that degrade the glycosyl-phosphatidylinositol anchor of membrane proteins, Martin G.Low
- biosynthesis of glycosyl-phosphatidylinositol membrane protein anchors, Mark C.Field, Anant K.Menon
- chemical and enzymic analysis of glycosyl-phosphatidylinositol anchors, A.J.Ferguson
- structural analysis of prenylated proteins, Michael H.Gelb, Christopher C.Farnsworth, John A.Glomset
- identification and characterization of lipid-modified proteins in bacteria, Shigeru Hayashi, Henry C.Wu.
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