Parkinson's disease
著者
書誌事項
Parkinson's disease
（Advances in neurology, v. 91）
Lippincott Williams & Wilkins, c2003
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Based on the XIVth International Congress on Parkinson's Disease, this volume provides a comprehensive account of the state of the art in the study and treatment of Parkinson's disease and related disorders. The book reviews the latest advances in all aspects of research and patient care, including neurobiology, genetics, epidemiology, PET and SPECT imaging, pharmacotherapy, surgical treatment, and management of comorbid and related conditions. Coverage of this title includes current recommendations for medical treatment of early and advanced Parkinson's disease, a detailed assessment of the benefits of deep brain stimulation, and guidelines for management of sleep disorders, depression, psychosis, and dementia in Parkinson's disease.
目次
Section I. Parkinson's Disease, Past and Present 1 Functional Anatomy of the Basal Ganglia in Parkinson's Disease 2 Parkinson Revisited: Pathophysiology of Motor Signs 3 The Role of Non Dopamine Neurons in Parkinson's Disease 4 Biochemistry of Parkinson's Disease 5 New Insights in Parkinson's Disease Therapy: Can Levodopa-induced Dyskinesia Ever be Manageable? 6 Imaging of Dopamine Receptors in Parkinson's Disease 7 The Molecular Mechanisms of Dopamine Toxicity 8 Free Radical and Nitric Oxidase Toxicity 9 Neuroregeneration 10 Estrogens and Aging 11 Estrogens and Parkinson's Disease Section II. Epidemiology ands Genetics 12 Burden of Parkinson's Disease: The Caregivers 13 Gene Expression and Oxidative Stress 14 Environmental Causes of Parkinson's Disease: Twin Studies 15 Overview of the Genetics of Parkinsonism 16 Hereditary Tauopathies and Parkinsonism 17 Alpha-Synuclein and Parkinsonism Section III. Imaging in Parkinson's Disease 18 Functional Brain Imaging in Parkinson's Disease 19 Single Photon Emission Tomography and Dopamine Transporter Imaging in Parkinson's Disease Section IV. Medical Treatment of Parkinson's Disease 20 Mechanisms (Pathophysiology) of Treatment Complications 21 How To Manage the Patient with Early Parkinson's Disease? 22 How To Manage the Patient with Advanced Parkinson's Disease? 23 Strategies To Modify Levodopa Treatment 24 Position of COMT Inhibition in Parkinson's Disease 25 Renaissance of Amantadine 26 Clinical Comparisons of Dopamine Agonists? 27 Dopaminergic Drugs in Development 28 Non-Dopaminergic Drugs in Development Section V. Surgical Treatment of Parkinson's Disease 29 Deep Brain Stimulation: What Does it Offer and Promise? 30 Surgery for Parkinson's Disease, the Five W's: Why, Who, What, Where and When Section VI. Comorbid Conditions 31 Preclinical Versus Clinical Neuroprotection 32 Sleep Disorders in Parkinson's Disease 33 Sleep AttacksuFacts and Fiction: A Critical View 34 Dopamine Agonists, Sleep Disorders and Driving in Parkinson's Disease 35 Dystonia in Parkinsonian Syndromes 36 Treatment of Dystonia in Parkinson's Disease 37 Parkinson's Disease is a Neuropsychiatric Disorder 38 Depression in Parkinson's Disease Section VII. Related Disorders 39 Differential Diagnosis of Parkinsonism 40 Essential Tremor and Parkinsonism 41 Dopa Responsive Dystonia: Genetic and Biochemical Aspects 42 Dementia in Parkinson's Diseas
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