DNA Binding and Cleaving Activity of Antitumor Metal Complex: Sodium <i>trans</i>-dinitrobis(2,4-pentanedionato)cobalt(III)

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  • Hiroshi Tamura
    Faculty of Engineering, Kansai University3-3-35 Yamate-cho, Suita, Osaka
  • Hiroyuki Fujita
    Faculty of Engineering, Kansai University3-3-35 Yamate-cho, Suita, Osaka

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Abstract

<jats:title>Abstract</jats:title> <jats:p>The antitumor metal complex, sodium trans-dinitrobis(2,4-pentanedionato)cobalt(III) bound to adenine rich regions of DNA helix and caused single strand scission under the irradiation of light.</jats:p>

Journal

  • Chemistry Letters

    Chemistry Letters 26 (8), 711-712, 1997-08-01

    Oxford University Press (OUP)

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