Cyclic AMP Detection by Electrode Modified with 17mer Oligopeptide

• Katayama Yoshiki

  Department of Chemical Science and Technology, Faculty of Engineering, Kyushu University

• Ohuchi Yuya

  Department of Chemical Science and Technology, Faculty of Engineering, Kyushu University

• Nakayama Masamichi

  Department of Chemical Science and Technology, Faculty of Engineering, Kyushu University

• Maeda Mizuo

  Department of Chemical Science and Technology, Faculty of Engineering, Kyushu University

• Higashi Hideyoshi

  Mitsubishi Kasei Institute for Life Sciences

• Kudo Yoshihisa

  Laboratory of Cellular Neurobiology, School of Life Science, Tokyo University of Pharmacy and Life Science

Abstract

An oligopeptide (17mer) which recognizes cyclic AMP was designed and applied to electrochemical detection of cAMP. Redox peak currents on cyclic voltammograms of ferrocyanide/ferricyanide redox couple with Au electrode which was modified with the peptide showed response dependently on the cAMP concentration, while the electrode showed only slight response to ATP that is a structural analog of cAMP.

Journal

• Chemistry Letters

  Chemistry Letters 26 (9), 883-884, 1997

  The Chemical Society of Japan

Keywords

• General Chemistry

Details

• CRID: 1390001204574469888
• NII Article ID: 10002614742
• NII Book ID: AA00603318
• DOI: 10.1246/cl.1997.883
• COI: 1:CAS:528:DyaK2sXmt1Kqs7k%3D
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/26/9/883/56073936/cl.1997.883.pdf
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed