^<14>N NMR Spectra Sensitively Reflect Surface Curvature and Segmental Motion of Hydrophilic Headgroups in Lipid Bilayers and Micelles
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To study the surface curvature dependence of the dynamical structure of the headgroups of phospholipids forming bilayers and micelles, <SUP>14</SUP>N NMR spectra were measured for liposomes of phosphatidylcholine and for micelles of lysophosphatidylcholine. Choline <SUP>14</SUP>N NMR signals were observed for the micelles and small unilamellar vesicles, which involve high surface curvatures. The signals vanished, on the other hand, when the diameter was increased from 55 to 100 nm in unilamellar vesicles.
- Chemistry Letters
Chemistry Letters 1997(10), 1061-1062, 1997-10
The Chemical Society of Japan