第7補体欠損症に合併した髄膜炎菌感染症

• 小崎 真規子

  国立病院東京医療センター総合診療科

• 尾藤 誠司

  国立病院東京医療センター総合診療科

• 新保 卓郎

  京都大学附属病院総合診療部

• 伊藤 澄信

  国立病院東京医療センター総合診療科

• 青木 誠

  国立病院東京医療センター総合診療科

書誌事項

タイトル別名

• Meningococcemia Associated with C7 Deficiency

抄録

We report a 20-year-old woman who developed meningococcemia. The patient developed fever, vomiting and skin rash, then was sent to our hospital for shock. Physical and laboratory examination revealed septic shock and DIC. Her blood culture grew Neisseria meningitidis (W135). She recovered promptly with PCG, gabexate mesilate and intensive care for shock.<BR>Hemolytic activities of the patient's complement were less than 12/CHSO during the course. Screening for each component of the complements suggested that this patient had deficiency of C7.<BR>Meningococcal disease has seldom seen in Japan. Early recognition is essential so that appropriate antibiotic therapy and supportive care can be promptly started because shock and death may ensure within hours after onset of symptoms.

収録刊行物

• 感染症学雑誌

  感染症学雑誌 74 (9), 720-723, 2000

  一般社団法人 日本感染症学会

キーワード

• meningococcemia
• C7 deficiency
• shock

詳細情報

• CRID: 1390282680024404608
• NII論文ID: 10008713478
• NII書誌ID: AN00047715
• DOI: 10.11150/kansenshogakuzasshi1970.74.720
• ISSN: 1884569X
• ISSN: 03875911
• PubMed: 11068366
• Web Site: https://search.jamas.or.jp/link/ui/2001049115
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可