CeCl3·7H2O/LiI: A Novel Reagent System for the Synthesis of 4-Iodotetrahydropyrans via Prins Cyclization

• J S Yadav

  Division of Organic Chemistry, Indian Institute of Chemical Technology

• B V Subba Reddy

  Division of Organic Chemistry, Indian Institute of Chemical Technology

• G G K S Narayana Kumar

  Division of Organic Chemistry, Indian Institute of Chemical Technology

• G Madhusudhan Reddy

  Division of Organic Chemistry, Indian Institute of Chemical Technology

Abstract

Homoallylic alcohols undergo smooth coupling with a variety of aldehydes in the presence of CeCl3·7H2O–LiI reagent system in refluxing dichloroethane under neutral conditions to produce the corresponding 4-iodotetrahydropyran derivatives in high yields. The spirocyclic-4-iodotetrahydropyrans are obtained in case of cyclic ketones.

Journal

• Chemistry Letters

  Chemistry Letters 36 (3), 426-427, 2007-02-17

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360846644041130624
• NII Article ID: 10018829830
• NII Book ID: AA00603318
• DOI: 10.1246/cl.2007.426
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/36/3/426/55593264/cl.2007.426.pdf
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