Correlation among Suppression of Leukotriene B4 Release, Radical Scavenging Activity and Polyphenol Contents of Commercial Tea Extract

• Takasugi Mikako

  Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University

• Kitagawa Tomoko

  Faculty of Human Life Science, Yamaguchi Prefectural University

• Kato Masako

  Faculty of Human Life Science, Mimasaka University

• Maeda Noriko

  Graduate School of Health and Welfare, Yamaguchi Prefectural University

• Nagata Noriko

  Faculty of Human Life Science, Yamaguchi Prefectural University

• Niwa Junko

  Faculty of Human Life Science, Yamaguchi Prefectural University

• Shimada Kazuko

  Graduate School of Health and Welfare, Yamaguchi Prefectural University

Bibliographic Information

Other Title

• 各種市販茶のロイコトリエンＢ４放出抑制作用とラジカル消去活性およびポリフェノール含量との関係
• カクシュ シハンチャ ノ ロイコトリエン B4 ホウシュツ ヨクセイ サヨウ ト ラジカル ショウキョ カッセイ オヨビ ポリフェノール ガンリョウ トノ カンケイ

Abstract

Anti-allergic effects of 16 commercial available tea extracts were examined by measuring leukotriene B₄ (LTB₄) release from rat peritoneal cells (PC). LTB₄ production is accomplished by oxidative reactions catalyzed by 5-lipoxygenase. As several kinds of tea include polyphenols that have anti-oxidative effects, we also determined the contents of total polyphenol, flavonol and tannin, and examined DPPH radical scavenging activity of the tea extracts. Guava, sweet tea (Rubus suavissimus S. Lee), rooibos, Quercus salicina, green tea, sweet tea (family unknown) and loquat contained large amount of polyphenols. Flavonol was found in guava, and tannin was found in guava and sweet tea (Rubus suavissimus S. Lee). The extracts of green tea and sweet tea (Rubus suavissimus S. Lee) almost completely inhibited LTB₄ release from PC, while extracts of ground ivy leaves, guava and Quercus salicina inhibited release by less than 50%. We also examined the correlation between LTB₄ release and DPPH radical scavenging activity and between LTB₄ release and polyphenol, flavonol, or tannin content. LTB₄ release was negatively correlated with DPPH radical scavenging activity and total polyphenol contents, and this correlation was strong among the tea extracts that suppressed LTB₄ release. These results suggest that polyphenols in tea extracts may play an important role in the suppression of LTB₄ release and may also scavenge arachidonic acid peroxyradicals in the production of LTB₄.

Journal

• Nippon Shokuhin Kagaku Kogaku Kaishi

  Nippon Shokuhin Kagaku Kogaku Kaishi 55 (3), 87-94, 2008

  Japanese Society for Food Science and Technology

Keywords

• tea
• allergy
• leukotriene
• radical
• polyphenol

Details

• CRID: 1390282681385090048
• NII Article ID: 10021178285
• NII Book ID: AN10467499
• DOI: 10.3136/nskkk.55.87
• COI: 1:CAS:528:DC%2BD1cXks1egtLY%3D
• ISSN: 18816681
• ISSN: 1341027X
• NDL BIB ID: 9413662
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9413662
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed