Cyclodextrins

Comprehensive Supramolecular Chemistry covers for the first time in eleven detailed volumes the exciting inter- and multidisciplinary area of modern supramolecular chemistry. This subject, which has now reached an astonishing diversity and complexity, has developed at a remarkably rapid pace following the initial discoveries of crown ethers and cryptands in the late sixties.The numerous references, including many recent citations, constitute an unrivalled in-depth source for direct entry to the widespread primary literature on any aspect of this most highly topical area. The many carefully selected illustrations and instructive schematic representations make the chapters easily readable.

Volume 1 - Molecular Recognition: Receptors for Cationic Guests. Volume 2 - Molecular Recognition: Receptors for Molecular Guests. Volume 3 - Cyclodextrins. Volume 4 - Supramolecular Reactivity and Transport: Bioorganic Systems. Volume 5 - Supramolecular Reactivity and Transport: Bioinorganic Systems. Volume 6 - Solid-State Supramolecular Chemistry: Crystal Engineering. Volume 7 - Solid-State Supramolecular Chemistry: Two- and Three-Dimensional Inorganic Networks. Volume 8 - Physical Methods in Supramolecular Chemistry. Volume 9 - Templating Self-Assembly and Self-Organization. Voulme 10 - Supramolecular Technology. Volume 11 - Cumulative Index.

The total number of papers, conferences, abstracts and patents dedicated to cyclodextrins by the end of 1995 will be about 12,000 in number. This vast number of publications deals with the chemistry (structure, chemical reactivity), biology (enzymology, metabolism, toxicity, direct therapeutic effects), inclusion complex forming capacity and its consequences, and industrial utilization of cyclodextrins (in drugs, foods, cosmetics, chromatography, catalysis biotechnology, diagnostics etc) in unlimited numbers of products and technologies.This volume pulls all this information together, covering the chemistry, biology and industrial application of cyclodextrins as molecular encapsulating agents in research methods, analytical procedures, industrial technologies and products.

Historical background (J. Szejtli). Chemistry, physical and biological properties and preparation (J. Szejtli). Industrial production of cyclodextrins (G. Schmid). Cyclodextrin derivatives (L. Jicsinszky, H. Hashimoto, E. Fenyvesi, A. Ueno). Inclusion of guest molecules, selectivity and molecular recognition by cyclodextrins (J. Szejtli). Measurement of cyclodextrin complex stability constants (K.A. Connors). Preparation of cyclodextrin complexes (L. Szente). Analytical methods for cyclodextrins, cyclodextrin derivatives, and cyclodextrin complexes (L. Szente). Crystallographic studies (K. Harata). Specific guest types (E. Fenyvesi, L. Szente, N.K. Russell, M. McNamara). Reactivity of included guests (T.Osa, I. Suzuki). Cyclodextrins as enzyme models (M. Komiyama, H. Shigekawa). Applications of cyclodextrins in biotechnology (R. Bar). Aspects of drug formulation with cyclodextrins (T. Nagai, H. Ueda). Pharmaceutical use of cyclodextrins in various drug formulations (K. Uekama, T. Irie). Cyclodextrins in foods, cosmetics, and toiletries (H. Hashimoto). Cyclodextrins in pesticides (L. Szente, J. Szejtli). Cyclodextrins in chromatography (D.J. Snopek, E. Smolkova-Keulemansova, T. Cserhati, K.H. Gahm, A.M. Stalcup). Separation, removal, or enrichment of components on preparative scale (A. Harada, B. Zsadon). Cyclodextrins as reagents in analytical chemistry and diagnostics (W.L. Hinze, W. Day, R.P. Frankewich, K.N. Thimaiah, J. Szejtli). Use of cyclodextrins in chemical products and processes (J. Szejtli). Enzymology of cyclodextrins (G. Schmid).