Switching Reaction Pathways of Benzo[<i>b</i>]thiophen-3-yllithium and Benzo[<i>b</i>]furan-3-yllithium Based on High-resolution Residence-time and Temperature Control in a Flow Microreactor

• Tatsuro Asai

  The Research Association of Micro Chemical Process Technology (MCPT) in Kyoto, Kyoto University

• Atsushi Takata

  Yamada Chemical Co., Ltd

• Yousuke Ushiogi

  Yamada Chemical Co., Ltd

• Yoshiharu Iinuma

  Yamada Chemical Co., Ltd

• Aiichiro Nagaki

  Department of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University

• Jun-ichi Yoshida

  Department of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University

Abstract

Reaction-pathway control of benzo[b]thiophen-3-yllithium and benzo[b]furan-3-yllithium was accomplished in flow microreactor systems. We could switch between the reaction with an electrophile before ring-opening and that after ring-opening at will by choosing an appropriate residence-time and temperature.

Journal

• Chemistry Letters

  Chemistry Letters 40 (4), 393-395, 2011-03-12

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360283694088251520
• NII Article ID: 10028170699
• NII Book ID: AA00603318
• DOI: 10.1246/cl.2011.393
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/40/4/393/55605222/cl.2011.393.pdf
• Data Source:
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  • CiNii Articles
  • KAKEN