<i>p</i>-Aminophenyl Alkyl Ether-based 19F MRI Probe for Specific Detection and Imaging of Hypochlorite Ion

• Tomohiro Doura

  INAMORI Frontier Research Center, Kyushu University

• Qi An

  INAMORI Frontier Research Center, Kyushu University

• Fuminori Sugihara

  Department of Systems Science, Graduate School of Informatics, Kyoto University

• Tetsuya Matsuda

  Department of Systems Science, Graduate School of Informatics, Kyoto University

• Shinsuke Sando

  INAMORI Frontier Research Center, Kyushu University

Abstract

We report a 19F MRI probe for the specific detection and imaging of −OCl. Our designed probe, having p-aminophenyl alkyl scaffold, reacted expeditiously with −OCl to produce a trifluoroethanol. Concomitant with the reaction, the 19F chemical shift changed by 2.6 ppm, allowing the visualization of −OCl-dependent probe-to-product conversion using 19F MRI.

Journal

• Chemistry Letters

  Chemistry Letters 40 (12), 1357-1359, 2011-11-19

  Oxford University Press (OUP)

Keywords

• General Chemistry

Details

• CRID: 1360565169064929152
• NII Article ID: 10030221016
• NII Book ID: AA00603318
• DOI: 10.1246/cl.2011.1357
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/40/12/1357/55606238/cl.2011.1357.pdf
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