pH-Induced Switchable Vesicular Aggregation of Zwitterionic and Anionic Phospholipids

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  • Kentaro Suzuki
    Research Center of Life Science as Complex Systems, The University of Tokyo
  • Kensuke Kurihara
    Department of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo
  • Yusaku Okura
    Department of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo
  • Taro Toyota
    Research Center of Life Science as Complex Systems, The University of Tokyo
  • Tadashi Sugawara
    Research Center of Life Science as Complex Systems, The University of Tokyo

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Abstract

<jats:title>Abstract</jats:title> <jats:p>Giant vesicles (GVs) comprising zwitterionic and anionic phospholipids (DOPC and POPG, respectively) at a molar ratio of 90:10 formed a sparse network of aggregates that dissociated into isolated GVs reversibly depending on the pH of the dispersion (pH range, 7.0–2.5). This reversibility was due to the fluctuations in the composition of as-grown GVs.</jats:p>

Journal

  • Chemistry Letters

    Chemistry Letters 41 (10), 1084-1086, 2012-10

    Oxford University Press (OUP)

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