Synthesis of Spirooxindoles from Carbamoyl Chlorides via Cyclopropyl Methine C(sp³)–H Activation Using Palladium Catalyst

• Tsukano Chihiro

  Graduate School of Pharmaceutical Sciences, Kyoto University

• Okuno Masataka

  Graduate School of Pharmaceutical Sciences, Kyoto University

• Takemoto Yoshiji

  Graduate School of Pharmaceutical Sciences, Kyoto University

Bibliographic Information

Other Title

• Synthesis of Spirooxindoles from Carbamoyl Chlorides via Cyclopropyl Methine C(sp3)–H Activation Using Palladium Catalyst

Abstract

The synthesis of spirooxindoles fused with cyclopropanes from carbamoyl chlorides, via methine C(sp³)–H activation, is reported. The regioselectivity of C–H activation in the presence of competitive C–H bonds at the appropriate position was investigated under the optimized conditions.

Journal

• Chemistry Letters

  Chemistry Letters 42 (7), 753-755, 2013

  The Chemical Society of Japan

Details

• CRID: 1390001204588372480
• NII Article ID: 10031183283
• NII Book ID: AA00603318
• DOI: 10.1246/cl.130228
• COI: 1:CAS:528:DC%2BC3sXhtF2ntbfP
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/42/7/753/55641235/cl.130228.pdf
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed